{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:20:28Z","timestamp":1792084828587,"version":"4.4.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.neulet.2007.03.051","type":"journal-article","created":{"date-parts":[[2007,3,31]],"date-time":"2007-03-31T11:19:10Z","timestamp":1175339950000},"page":"78-82","source":"Crossref","is-referenced-by-count":19,"title":["Nerve growth factor in serum is a marker of the stage of alcohol disease"],"prefix":"10.1016","volume":"419","author":[{"given":"Maria C.","family":"Jockers-Scher\u00fcbl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armin","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"Kuhn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedel","family":"Reischies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Danker-Hopfe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz G.","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Rentzsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Hellweg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2007.03.051_bib1","unstructured":"Alcohol, the brain, and behavior, Mechanisms of addiction, Alcohol Res. Health 24 (2000) 12\u201315."},{"key":"10.1016\/j.neulet.2007.03.051_bib2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0306-4522(88)90217-5","article-title":"New perspectives in basal forebrain organization of spezial relevance for neuropsychiatric disorders: the striatopallidal, amygdaloid, and corticopetal components of substantia innominata","volume":"27","author":"Alheid","year":"1988","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2007.03.051_bib3","doi-asserted-by":"crossref","first-page":"10440","DOI":"10.1073\/pnas.91.22.10440","article-title":"Emotional stress induced by parachute jumping enhances blood nerve growth factor levels and the distribution of nerve growth factor receptors in lymphocytes","volume":"91","author":"Aloe","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neulet.2007.03.051_bib4","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1530-0277.1996.tb01076.x","article-title":"Changes in human plasma nerve growth factor level after chronic alcohol consumption and withdrawal","volume":"20","author":"Aloe","year":"1996","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.neulet.2007.03.051_bib5","series-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"1994"},{"key":"10.1016\/j.neulet.2007.03.051_bib6","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s002340050342","article-title":"Incidental white-matter foci on MRI in \u201chealthy\u201d subjects: evidence of subtle cognitive dysfunction","volume":"38","author":"Baum","year":"1996","journal-title":"Neuroradiology"},{"key":"10.1016\/j.neulet.2007.03.051_bib7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.neulet.2007.03.051_bib8","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/s00702-005-0361-x","article-title":"Chronic alcohol intoxication in rats leads to a strong but transient increase in NGF levels in distinct brain regions","volume":"113","author":"Gericke","year":"2006","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.neulet.2007.03.051_bib9","first-page":"43","article-title":"An improved rapid and highly sensitive enzyme immunoassay for nerve growth factor","volume":"1","author":"Hellweg","year":"1989","journal-title":"Technique J. Methods Cell. Mol. Biol."},{"key":"10.1016\/j.neulet.2007.03.051_bib10","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1101\/lm.2606","article-title":"Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signalling as a biological marker of early impairment","volume":"13","author":"Hellweg","year":"2006","journal-title":"Learn. Mem."},{"key":"10.1016\/j.neulet.2007.03.051_bib11","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s007020050100","article-title":"The time course of nerve growth factor content in different neuropsychiatric diseases: a unifying hypothesis","volume":"105","author":"Hellweg","year":"1998","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.neulet.2007.03.051_bib12","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/j.1530-0277.2006.00026.x","article-title":"Big news in alcohol addiction: new findings on growth factor pathways BDNF, insulin and GDNF","volume":"30","author":"Janak","year":"2006","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.neulet.2007.03.051_bib13","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.pnpbp.2006.09.006","article-title":"Nerve growth factor serum concentrations rise after successful cognitive behavioural therapy of generalized anxiety disorder","volume":"31","author":"Jockers-Scher\u00fcbl","year":"2007","journal-title":"Prog. Neuropsychoph. Biol. Psych."},{"key":"10.1016\/j.neulet.2007.03.051_bib14","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/10253890310001638145","article-title":"Measurement of nerve growth factor serum concentrations in a psychologically stressful situation in men","volume":"7","author":"Lang","year":"2004","journal-title":"Stress"},{"key":"10.1016\/j.neulet.2007.03.051_bib15","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0304-3940(03)00403-8","article-title":"Nerve growth factor serum concentrations in healthy human volunteers: physiological variance and stability","volume":"344","author":"Lang","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2007.03.051_bib16","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1176\/appi.ajp.159.4.674-a","article-title":"Nerve growth factor and smoking cessation","volume":"159","author":"Lang","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neulet.2007.03.051_bib17","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00702-003-0100-0","article-title":"State of the art of the neurotrophin hypothesis in psychiatric disorders: implications and limitations","volume":"111","author":"Lang","year":"2004","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.neulet.2007.03.051_bib18","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/S0166-2236(96)10058-8","article-title":"Nerve growth factor: from neurotrophin to neurokine","volume":"19","author":"Levi-Montalcini","year":"1996","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neulet.2007.03.051_bib19","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.ne.19.030196.001445","article-title":"Physiology of the neurotrophins","volume":"19","author":"Lewin","year":"1996","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.neulet.2007.03.051_bib20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.pharmthera.2003.10.002","article-title":"Recent advances in the neurobiology of alcoholism: the role of adenosine","volume":"101","author":"Maillard","year":"2004","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.neulet.2007.03.051_bib21","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1136\/jnnp.2004.045708","article-title":"Alcohol and the nervous system","volume":"75","author":"McIntosh","year":"2004","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neulet.2007.03.051_bib22","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1192\/bjp.175.2.114","article-title":"Alcohol and the brain","volume":"175","author":"Nutt","year":"1999","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.neulet.2007.03.051_bib23","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1176\/ajp.139.9.1136","article-title":"The global deterioration scale (GDS) for assessment of primary degenerative dementia","volume":"139","author":"Reisberg","year":"1982","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neulet.2007.03.051_bib24","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00004714-198111000-00006","article-title":"Development of optimal treatment tactics for alcohol withdrawal. I. Assessment and effectiveness of supportive care","volume":"1","author":"Shaw","year":"1981","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.neulet.2007.03.051_bib25","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BFb0031026","article-title":"The physiological function of nerve growth factor in the central nervous system: comparison with the periphery","volume":"109","author":"Thoenen","year":"1987","journal-title":"Rev. Physiol. Biochem. Pharmacol."},{"key":"10.1016\/j.neulet.2007.03.051_bib26","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1111\/j.1530-0277.2006.00120.x","article-title":"Possible role of nerve growth factor in the pathogenesis of alcohol dependence","volume":"30","author":"Yoon","year":"2006","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.neulet.2007.03.051_bib27","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1017\/S0033291700014811","article-title":"SIDAM\u2014a structured interview for the diagnosis of dementia of the Alzheimer type, multi-infarct dementia and dementias of other aetiology according to ICD-10 and DSM-III-R","volume":"21","author":"Zaudig","year":"1991","journal-title":"Psychol. Med."},{"key":"10.1016\/j.neulet.2007.03.051_bib28","doi-asserted-by":"crossref","unstructured":"A. Ziegenhorn, O. Schulte-Herbr\u00fcggen, H. Danker-Hopfe, M. Malbranc, H.D. Hartung, D. Anders, U.E. Lang, E. Steinhagen-Thiessen, R. Schaub, R. Hellweg, Serum neurotrophins\u2014a study on the time course and influencing factors in a large old age sample, Neurobiol. Aging, 2006 (Epub ahead of print).","DOI":"10.1016\/j.neurobiolaging.2006.06.011"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394007003758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394007003758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T23:26:32Z","timestamp":1556321192000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394007003758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0304394007003758"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2007.03.051","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}