{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:30:34Z","timestamp":1792711834336,"version":"4.5.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1016\/j.neulet.2008.07.041","type":"journal-article","created":{"date-parts":[[2008,7,23]],"date-time":"2008-07-23T08:22:41Z","timestamp":1216801361000},"page":"46-50","source":"Crossref","is-referenced-by-count":150,"title":["Treatment of chronic thoracic spinal cord injury patients with autologous Schwann cell transplantation: An interim report on safety considerations and possible outcomes"],"prefix":"10.1016","volume":"443","author":[{"given":"Hooshang","family":"Saberi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pouria","family":"Moshayedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid-Reza","family":"Aghayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Arjmand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed-Kazem","family":"Hosseini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed-Hassan","family":"Emami-Razavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vafa","family":"Rahimi-Movaghar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsin","family":"Raza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoumeh","family":"Firouzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2008.07.041_bib1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0079-6123(06)61015-7","article-title":"Update on the treatment of spinal cord injury","volume":"161","author":"Baptiste","year":"2007","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.neulet.2008.07.041_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3727\/000000005783983106","article-title":"Survival, integration, and axon growth support of glia transplanted into the chronically contused spinal cord","volume":"14","author":"Barakat","year":"2005","journal-title":"Cell Transplant."},{"key":"10.1016\/j.neulet.2008.07.041_bib3","doi-asserted-by":"crossref","first-page":"14069","DOI":"10.1073\/pnas.0507063102","article-title":"Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice","volume":"102","author":"Cummings","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neulet.2008.07.041_bib4","first-page":"107","article-title":"Assessment of the malignant potential of mitogen stimulated human Schwann cells","volume":"4","author":"Emery","year":"1999","journal-title":"J. Peripher. Nerv. Syst."},{"key":"10.1016\/j.neulet.2008.07.041_bib5","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1055\/s-2000-10920","article-title":"Cultivating human Schwann cells for tissue engineering of peripheral nerves","volume":"32","author":"Fansa","year":"2000","journal-title":"Handchir. Mikrochir. Plast. Chir."},{"key":"10.1016\/j.neulet.2008.07.041_bib6","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/sj.sc.3102007","article-title":"Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials","volume":"45","author":"Fawcett","year":"2007","journal-title":"Spinal Cord"},{"key":"10.1016\/j.neulet.2008.07.041_bib7","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1093\/brain\/awh657","article-title":"Autologous olfactory ensheathing cell transplantation in human spinal cord injury","volume":"128","author":"Feron","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.neulet.2008.07.041_bib8","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neulet.2006.03.070","article-title":"Transplantation of Schwann cells to subarachnoid space induces repair in contused rat spinal cord","volume":"402","author":"Firouzi","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2008.07.041_bib9","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1002\/jnr.20029","article-title":"Acute transplantation of olfactory ensheathing cells or Schwann cells promotes recovery after spinal cord injury in the rat","volume":"75","author":"Garcia-Alias","year":"2004","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neulet.2008.07.041_bib10","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.expneurol.2004.11.033","article-title":"Demyelination and Schwann cell responses adjacent to injury epicenter cavities following chronic human spinal cord injury","volume":"192","author":"Guest","year":"2005","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2008.07.041_bib11","first-page":"1488","article-title":"Influence of patients\u2019 age on functional recovery after transplantation of olfactory ensheathing cells into injured spinal cord injury","volume":"116","author":"Huang","year":"2003","journal-title":"Chin. Med. J. (Engl.)"},{"key":"10.1016\/j.neulet.2008.07.041_bib12","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1089\/152581601317211015","article-title":"Human intrathecal transplantation of peripheral blood stem cells in amyotrophic lateral sclerosis","volume":"10","author":"Janson","year":"2001","journal-title":"J. Hematother. Stem Cell Res."},{"key":"10.1016\/j.neulet.2008.07.041_bib13","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/jnen\/63.9.919","article-title":"Long-term denervation in humans causes degeneration of both contractile and excitation\u2013contraction coupling apparatus, which is reversible by functional electrical stimulation (FES): a role for myofiber regeneration?","volume":"63","author":"Kern","year":"2004","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neulet.2008.07.041_bib14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3171\/spi.2005.3.3.0173","article-title":"Clinical experience using incubated autologous macrophages as a treatment for complete spinal cord injury: phase I study results","volume":"3","author":"Knoller","year":"2005","journal-title":"J. Neurosurg. Spine"},{"key":"10.1016\/j.neulet.2008.07.041_bib15","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/sj.sc.3102010","article-title":"Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design","volume":"45","author":"Lammertse","year":"2007","journal-title":"Spinal Cord"},{"key":"10.1016\/j.neulet.2008.07.041_bib16","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1046\/j.1537-2995.2001.41020276.x","article-title":"Quantitation of genomic DNA in plasma and serum samples: higher concentrations of genomic DNA found in serum than in plasma","volume":"41","author":"Lee","year":"2001","journal-title":"Transfusion"},{"key":"10.1016\/j.neulet.2008.07.041_bib17","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/00007632-199302000-00020","article-title":"Lumbar spinal stenosis: clinical\/radiologic therapeutic evaluation in 145 patients. Conservative treatment or surgical intervention?","volume":"18","author":"Onel","year":"1993","journal-title":"Spine"},{"key":"10.1016\/j.neulet.2008.07.041_bib18","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1089\/neu.2006.23.453","article-title":"Schwann cell transplantation for repair of the adult spinal cord","volume":"23","author":"Oudega","year":"2006","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2008.07.041_bib19","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1089\/ten.2005.11.913","article-title":"Treatment of complete spinal cord injury patients by autologous bone marrow cell transplantation and administration of granulocyte\u2013macrophage colony stimulating factor","volume":"11","author":"Park","year":"2005","journal-title":"Tissue Eng."},{"key":"10.1016\/j.neulet.2008.07.041_bib20","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.biopha.2003.05.001","article-title":"Transplantation treatment of spinal cord injury patients","volume":"57","author":"Rabinovich","year":"2003","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.neulet.2008.07.041_bib21","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/nm0798-814","article-title":"Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats","volume":"4","author":"Rapalino","year":"1998","journal-title":"Nat. Med."},{"key":"10.1016\/j.neulet.2008.07.041_bib22","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/284264a0","article-title":"Axons from CNS neurons regenerate into PNS grafts","volume":"284","author":"Richardson","year":"1980","journal-title":"Nature"},{"issue":"Suppl.","key":"10.1016\/j.neulet.2008.07.041_bib23","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/3-211-27577-0_25","article-title":"Macrophages and dendritic cells treatment of spinal cord injury: from the bench to the clinic","volume":"93","author":"Schwartz","year":"2005","journal-title":"Acta Neurochir."},{"key":"10.1016\/j.neulet.2008.07.041_bib24","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.juro.2006.08.059","article-title":"The effects of spinal cord injury on psychogenic sexual arousal in males","volume":"177","author":"Sipski","year":"2007","journal-title":"J. Urol."},{"key":"10.1016\/j.neulet.2008.07.041_bib25","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/sj.sc.3102008","article-title":"Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures","volume":"45","author":"Steeves","year":"2007","journal-title":"Spinal Cord"},{"key":"10.1016\/j.neulet.2008.07.041_bib26","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1007\/s10571-006-9007-2","article-title":"Bone marrow stem cells and polymer hydrogels: two strategies for spinal cord injury repair","volume":"26","author":"Sykova","year":"2006","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.neulet.2008.07.041_bib27","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1227\/01.NEU.0000245591.16087.89","article-title":"Review of treatment trials in human spinal cord injury: issues, difficulties, and recommendations","volume":"59","author":"Tator","year":"2006","journal-title":"Neurosurgery"},{"key":"10.1016\/j.neulet.2008.07.041_bib28","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/sj.sc.3102009","article-title":"Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion\/exclusion criteria and ethics","volume":"45","author":"Tuszynski","year":"2007","journal-title":"Spinal Cord"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030439400801015X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030439400801015X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T21:58:01Z","timestamp":1557698281000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030439400801015X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S030439400801015X"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2008.07.041","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}