{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T04:22:09Z","timestamp":1789878129450,"version":"4.0.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.neulet.2009.03.077","type":"journal-article","created":{"date-parts":[[2009,3,30]],"date-time":"2009-03-30T21:54:44Z","timestamp":1238450084000},"page":"44-48","source":"Crossref","is-referenced-by-count":92,"title":["Regional brain gray matter abnormalities in patients with bipolar II disorder: A comparison study with bipolar I patients and healthy controls"],"prefix":"10.1016","volume":"456","author":[{"given":"Tae Hyon","family":"Ha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyooseob","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hyoung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Eun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2009.03.077_bib1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.biopsych.2005.03.022","article-title":"Changes in gray matter volume in patients with bipolar disorder","volume":"58","author":"Adler","year":"2005","journal-title":"Biol. Psychiatry"},{"issue":"Suppl. 1","key":"10.1016\/j.neulet.2009.03.077_bib2","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/S0165-0327(00)00203-2","article-title":"Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders","volume":"59","author":"Akiskal","year":"2000","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib3","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1176\/ajp.152.8.1139","article-title":"T2 hyperintensities in bipolar disorder: magnetic resonance imaging comparison and literature meta-analysis","volume":"152","author":"Altshuler","year":"1995","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib4","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994"},{"key":"10.1016\/j.neulet.2009.03.077_bib5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0165-0327(98)00142-6","article-title":"The emerging epidemiology of hypomania and bipolar II disorder","volume":"50","author":"Angst","year":"1998","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib6","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1176\/ajp.156.12.1986","article-title":"Rostral and orbital prefrontal cortex dysfunction in the manic state of bipolar disorder","volume":"156","author":"Blumberg","year":"1999","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib7","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0149-7634(02)00007-6","article-title":"Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex","volume":"26","author":"Cardinal","year":"2002","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neulet.2009.03.077_bib8","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/j.1399-5618.2005.00230.x","article-title":"Evidence for orbitofrontal pathology in bipolar disorder and major depression, but not in schizophrenia","volume":"7","author":"Cotter","year":"2005","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib9","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/j.1749-6632.1999.tb09292.x","article-title":"Prefrontal cortical-amygdalar metabolism in major depression","volume":"877","author":"Drevets","year":"1999","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.neulet.2009.03.077_bib10","first-page":"31","article-title":"Heritable factors in the severity of affective illness","volume":"11","author":"Dunner","year":"1976","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib11","doi-asserted-by":"crossref","first-page":"6159","DOI":"10.1523\/JNEUROSCI.20-16-06159.2000","article-title":"Dissociable neural responses in human reward systems","volume":"20","author":"Elliott","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2009.03.077_bib12","series-title":"Structured Clinical Interview for DSM-IV Axis I disorder","author":"First","year":"1996"},{"key":"10.1016\/j.neulet.2009.03.077_bib13","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1006\/nimg.2001.1037","article-title":"Thresholding of statistical maps in functional neuroimaging using the false discovery rate","volume":"15","author":"Genovese","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.neulet.2009.03.077_bib14","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1006\/nimg.2001.0786","article-title":"A voxel-based morphometric study of ageing in 465 normal adult human brains","volume":"14","author":"Good","year":"2001","journal-title":"Neuroimage"},{"key":"10.1016\/j.neulet.2009.03.077_bib15","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib16","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0165-0327(99)00154-8","article-title":"MRI-based measurements of temporal lobe and ventricular structures in patients with bipolar I and bipolar II disorders","volume":"60","author":"Hauser","year":"2000","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib17","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.biopsych.2005.01.002","article-title":"Fronto-thalamo-striatal gray and white matter volumes and anisotropy of their connections in bipolar spectrum illnesses","volume":"57","author":"Haznedar","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib18","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1600-0447.1993.tb03372.x","article-title":"The distinction of bipolar II disorder from bipolar I and recurrent unipolar depression: results of a controlled family study","volume":"87","author":"Heun","year":"1993","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.neulet.2009.03.077_bib19","series-title":"Social Class and Mental Illness: A Community Study","author":"Hollingshead","year":"1958"},{"key":"10.1016\/j.neulet.2009.03.077_bib20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1001\/archpsyc.60.3.261","article-title":"A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder","volume":"60","author":"Judd","year":"2003","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib21","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1001\/archpsyc.65.9.1017","article-title":"Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder","volume":"65","author":"Kempton","year":"2008","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib22","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1097\/WNR.0b013e328310af58","article-title":"Abnormal corticostriatal activity during fear perception in bipolar disorder","volume":"19","author":"Killgore","year":"2008","journal-title":"Neuroreport"},{"key":"10.1016\/j.neulet.2009.03.077_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1399-5618.2008.00435.x","article-title":"Volumetric neuroimaging investigations in mood disorders: bipolar disorder versus major depressive disorder","volume":"10","author":"Konarski","year":"2008","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib24","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1399-5618.2006.00282.x","article-title":"Stroop performance in bipolar disorder: further evidence for abnormalities in the ventral prefrontal cortex","volume":"8","author":"Kronhaus","year":"2006","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib25","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0006-3223(02)01350-1","article-title":"Regional prefrontal gray and white matter abnormalities in bipolar disorder","volume":"52","author":"Lopez-Larson","year":"2002","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib26","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1034\/j.1399-5618.2003.00041.x","article-title":"Oral choline decreases brain purine levels in lithium-treated subjects with rapid-cycling bipolar disorder: a double-blind trial using proton and lithium magnetic resonance spectroscopy","volume":"5","author":"Lyoo","year":"2003","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib27","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4088\/JCP.v68n0205","article-title":"Health-related quality of life in euthymic bipolar disorder patients: differences between bipolar I and II subtypes","volume":"68","author":"Maina","year":"2007","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib28","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.biopsych.2004.06.021","article-title":"Meta-analysis of magnetic resonance imaging brain morphometry studies in bipolar disorder","volume":"56","author":"McDonald","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib29","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1177\/070674370404901202","article-title":"Neurobiological findings in bipolar II disorder compared with findings in bipolar I disorder","volume":"49","author":"McGrath","year":"2004","journal-title":"Can. J. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib30","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1001\/archpsyc.58.11.1025","article-title":"Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder","volume":"58","author":"McMahon","year":"2001","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib31","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1001\/archpsyc.64.5.543","article-title":"Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication","volume":"64","author":"Merikangas","year":"2007","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib32","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0193-953X(05)70101-5","article-title":"Bipolar II disorder and suicidal behavior","volume":"22","author":"Rihmer","year":"1999","journal-title":"Psychiatr. Clin. North Am."},{"key":"10.1016\/j.neulet.2009.03.077_bib33","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1399-5618.2007.00492.x","article-title":"Neurocognitive profiles in bipolar I and bipolar II disorder: differences in pattern and magnitude of dysfunction","volume":"10","author":"Simonsen","year":"2008","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neulet.2009.03.077_bib34","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1176\/ajp.150.6.901","article-title":"Bipolar II: the most common bipolar phenotype?","volume":"150","author":"Simpson","year":"1993","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib35","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/sj.mp.4001585","article-title":"The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings","volume":"10","author":"Strakowski","year":"2005","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib36","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1192\/bjp.bp.105.017269","article-title":"Cognitive impairment in bipolar II disorder","volume":"189","author":"Torrent","year":"2006","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.neulet.2009.03.077_bib37","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.pscychresns.2004.01.004","article-title":"Voxel-based morphometry in adolescents with bipolar disorder: first results","volume":"131","author":"Wilke","year":"2004","journal-title":"Psychiatry Res."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394009003899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394009003899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T17:48:54Z","timestamp":1684950534000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394009003899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S0304394009003899"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2009.03.077","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}