{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T16:58:05Z","timestamp":1765040285610},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.neulet.2010.08.065","type":"journal-article","created":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T09:35:25Z","timestamp":1283333725000},"page":"65-70","source":"Crossref","is-referenced-by-count":20,"title":["A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation"],"prefix":"10.1016","volume":"485","author":[{"given":"Kazuya","family":"Motomura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Ogura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Natsume","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidenori","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Wakabayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2010.08.065_bib0005","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1054\/bjoc.1999.0912","article-title":"Cognitive and academic outcome following cranial irradiation and chemotherapy in children: a longitudinal study","volume":"82","author":"Anderson","year":"2000","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.neulet.2010.08.065_bib0010","first-page":"350","article-title":"Biochemistry of free radicals: from electrons to tissues","volume":"58","author":"Boveris","year":"1998","journal-title":"Medicina (B Aires)"},{"key":"10.1016\/j.neulet.2010.08.065_bib0015","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1126\/science.1173215","article-title":"A functional role for adult hippocampal neurogenesis in spatial pattern separation","volume":"325","author":"Clelland","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.neulet.2010.08.065_bib0020","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1200\/JCO.1994.12.3.627","article-title":"Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy","volume":"12","author":"Crossen","year":"1994","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.neulet.2010.08.065_bib0025","first-page":"188","article-title":"Free-radical reaction in biological systems","volume":"62","author":"Dormandy","year":"1980","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"10.1016\/j.neulet.2010.08.065_bib0030","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0166-4328(88)90157-X","article-title":"A new one-trial test for neurobiological studies of memory in rats. 1. Behavioral data","volume":"31","author":"Ennaceur","year":"1988","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neulet.2010.08.065_bib0035","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0166-4328(96)00006-X","article-title":"Neurotoxic lesions of the perirhinal cortex do not mimic the behavioural effects of fornix transection in the rat","volume":"80","author":"Ennaceur","year":"1996","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neulet.2010.08.065_bib0040","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/(SICI)1097-4695(199808)36:2<249::AID-NEU11>3.0.CO;2-9","article-title":"Multipotent progenitor cells in the adult dentate gyrus","volume":"36","author":"Gage","year":"1998","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.neulet.2010.08.065_bib0045","doi-asserted-by":"crossref","first-page":"685","DOI":"10.2165\/00002512-200118090-00004","article-title":"Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment","volume":"18","author":"Halliwell","year":"2001","journal-title":"Drugs Aging"},{"key":"10.1016\/j.neulet.2010.08.065_bib0050","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3109\/10408448709089856","article-title":"Lipid peroxidation and mechanisms of toxicity","volume":"18","author":"Horton","year":"1987","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.neulet.2010.08.065_bib0055","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.neulet.2007.07.029","article-title":"The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress","volume":"423","author":"Ishii","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2010.08.065_bib0060","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/BF02690894","article-title":"The putative role of free radicals in the loss of neuronal functioning in senescence","volume":"27","author":"Joseph","year":"1992","journal-title":"Integr. Physiol. Behav. Sci."},{"key":"10.1016\/j.neulet.2010.08.065_bib0065","first-page":"4021","article-title":"Extreme sensitivity of adult neurogenesis to low doses of X-irradiation","volume":"63","author":"Mizumatsu","year":"2003","journal-title":"Cancer Res."},{"key":"10.1016\/j.neulet.2010.08.065_bib0070","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/nm749","article-title":"Irradiation induces neural precursor-cell dysfunction","volume":"8","author":"Monje","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.neulet.2010.08.065_bib0075","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00019052-200304000-00002","article-title":"Radiation injury and neurogenesis","volume":"16","author":"Monje","year":"2003","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.neulet.2010.08.065_bib0080","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1126\/science.1088417","article-title":"Inflammatory blockade restores adult hippocampal neurogenesis","volume":"302","author":"Monje","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.neulet.2010.08.065_bib0085","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0165-0270(84)90007-4","article-title":"Developments of a water-maze procedure for studying spatial learning in the rat","volume":"11","author":"Morris","year":"1984","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.neulet.2010.08.065_bib0090","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.bbr.2005.10.014","article-title":"Inhibition of neprilysin by thiorphan (i.c.v.) causes an accumulation of amyloid beta and impairment of learning and memory","volume":"168","author":"Mouri","year":"2006","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neulet.2010.08.065_bib0095","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0169-328X(99)00170-9","article-title":"Ionizing radiation-induced apoptosis of proliferating stem cells in the dentate gyrus of the adult rat hippocampus","volume":"71","author":"Peissner","year":"1999","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neulet.2010.08.065_bib0100","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1089\/ars.2006.8.381","article-title":"Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by l-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress","volume":"8","author":"Poon","year":"2006","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.neulet.2010.08.065_bib0105","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/09553009414550041","article-title":"Free radicals in biology: oxidative stress and the effects of ionizing radiation","volume":"65","author":"Riley","year":"1994","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.neulet.2010.08.065_bib0110","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.niox.2007.11.003","article-title":"Edaravone prevents iNOS expression by inhibiting its promoter transactivation and mRNA stability in cytokine-stimulated hepatocytes","volume":"18","author":"Yoshida","year":"2008","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.neulet.2010.08.065_bib0115","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1161\/01.STR.0000182241.07096.06","article-title":"Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain","volume":"36","author":"Zhang","year":"2005","journal-title":"Stroke"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394010011456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394010011456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T21:10:26Z","timestamp":1559509826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394010011456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0304394010011456"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2010.08.065","relation":{},"ISSN":["0304-3940"],"issn-type":[{"type":"print","value":"0304-3940"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}