{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:55:07Z","timestamp":1792637707122,"version":"4.5.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.neulet.2010.11.056","type":"journal-article","created":{"date-parts":[[2010,12,2]],"date-time":"2010-12-02T09:38:45Z","timestamp":1291282725000},"page":"10-15","source":"Crossref","is-referenced-by-count":29,"title":["Pikachurin interaction with dystroglycan is diminished by defective O-mannosyl glycosylation in congenital muscular dystrophy models and rescued by LARGE overexpression"],"prefix":"10.1016","volume":"489","author":[{"given":"Huaiyu","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2010.11.056_bib0005","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/brain\/awn335","article-title":"Reduced expression of fukutin related protein in mice results in a model for fukutin related protein associated muscular dystrophies","volume":"132","author":"Ackroyd","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.neulet.2010.11.056_bib0010","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/glycob\/cwp074","article-title":"Mutational and functional analysis of Large in a novel CHO glycosylation mutant","volume":"19","author":"Aguilan","year":"2009","journal-title":"Glycobiology"},{"key":"10.1016\/j.neulet.2010.11.056_bib0015","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/nm1059","article-title":"LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies","volume":"10","author":"Barresi","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.neulet.2010.11.056_bib0020","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1074\/jbc.272.4.2156","article-title":"Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with laminin","volume":"272","author":"Chiba","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neulet.2010.11.056_bib0025","first-page":"3646","article-title":"The effects of dystrophin gene mutations on the ERG in mice and humans","volume":"34","author":"Cibis","year":"1993","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0030","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/ng0593-87","article-title":"New mdx mutation disrupts expression of muscle and nonmuscle isoforms of dystrophin","volume":"4","author":"Cox","year":"1993","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neulet.2010.11.056_bib0035","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1083\/jcb.122.4.809","article-title":"A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin","volume":"122","author":"Ervasti","year":"1993","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neulet.2010.11.056_bib0040","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1172\/JCI117250","article-title":"Retinal signal transmission in Duchenne muscular dystrophy: evidence for dysfunction in the photoreceptor\/depolarizing bipolar cell pathway","volume":"93","author":"Fitzgerald","year":"1994","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neulet.2010.11.056_bib0045","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0092-8674(94)90052-3","article-title":"Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor","volume":"77","author":"Gee","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.neulet.2010.11.056_bib0050","doi-asserted-by":"crossref","first-page":"6309","DOI":"10.1523\/JNEUROSCI.22-15-06309.2002","article-title":"Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage","volume":"22","author":"Gorski","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0055","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1093\/hmg\/11.21.2673","article-title":"Skeletal, cardiac and tongue muscle pathology, defective retinal transmission, and neuronal migration defects in the Large(myd) mouse defines a natural model for glycosylation-deficient muscle\u2013eye\u2013brain disorders","volume":"11","author":"Holzfeind","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neulet.2010.11.056_bib0060","first-page":"1415","article-title":"Retinal ectopias and mechanically weakened basement membrane in a mouse model of muscle\u2013eye\u2013brain (MEB) disease congenital muscular dystrophy","volume":"16","author":"Hu","year":"2010","journal-title":"Mol. Vis."},{"key":"10.1016\/j.neulet.2010.11.056_bib0065","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M110.116343","article-title":"Post-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localization","author":"Kanagawa","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neulet.2010.11.056_bib0070","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.mcn.2005.07.009","article-title":"Ocular abnormalities in Large(myd) and Large(vls) mice, spontaneous models for muscle, eye, and brain diseases","volume":"30","author":"Lee","year":"2005","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0075","doi-asserted-by":"crossref","first-page":"9399","DOI":"10.1523\/JNEUROSCI.19-21-09399.1999","article-title":"Disruption of laminin beta2 chain production causes alterations in morphology and function in the CNS","volume":"19","author":"Libby","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0080","doi-asserted-by":"crossref","first-page":"6517","DOI":"10.1523\/JNEUROSCI.20-17-06517.2000","article-title":"Laminin expression in adult and developing retinae: evidence of two novel CNS laminins","volume":"20","author":"Libby","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0085","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.mod.2005.12.003","article-title":"A genetic model for muscle\u2013eye\u2013brain disease in mice lacking protein O-mannose beta1,2-N-acetylglucosaminyltransferase (POMGnT1)","volume":"123","author":"Liu","year":"2006","journal-title":"Mech. Dev."},{"key":"10.1016\/j.neulet.2010.11.056_bib0090","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1073\/pnas.0307228101","article-title":"Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity","volume":"101","author":"Manya","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neulet.2010.11.056_bib0095","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nature00837","article-title":"Post-translational disruption of dystroglycan-ligand interactions in congenital muscular dystrophies","volume":"418","author":"Michele","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2010.11.056_bib0100","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/nature00838","article-title":"Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy","volume":"418","author":"Moore","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2010.11.056_bib0105","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.nurt.2008.08.005","article-title":"Muscular dystrophies due to glycosylation defects","volume":"5","author":"Muntoni","year":"2008","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.neulet.2010.11.056_bib0110","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/dvg.20335","article-title":"A global double-fluorescent Cre reporter mouse","volume":"45","author":"Muzumdar","year":"2007","journal-title":"Genesis"},{"key":"10.1016\/j.neulet.2010.11.056_bib0115","doi-asserted-by":"crossref","first-page":"20851","DOI":"10.1074\/jbc.M500069200","article-title":"Mouse large can modify complex N- and mucin O-glycans on alpha-dystroglycan to induce laminin binding","volume":"280","author":"Patnaik","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neulet.2010.11.056_bib0120","doi-asserted-by":"crossref","first-page":"475","DOI":"10.3109\/15419069809005605","article-title":"The relationship between perlecan and dystroglycan and its implication in the formation of the neuromuscular junction","volume":"5","author":"Peng","year":"1998","journal-title":"Cell Adhes. Commun."},{"key":"10.1016\/j.neulet.2010.11.056_bib0125","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/ng0593-82","article-title":"Dystrophin expression in the human retina is required for normal function as defined by electroretinography","volume":"4","author":"Pillers","year":"1993","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neulet.2010.11.056_bib0130","first-page":"462","article-title":"mdxCv3 mouse is a model for electroretinography of Duchenne\/Becker muscular dystrophy","volume":"36","author":"Pillers","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0135","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/nn.2160","article-title":"Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation","volume":"11","author":"Sato","year":"2008","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0140","doi-asserted-by":"crossref","first-page":"13136","DOI":"10.1523\/JNEUROSCI.0474-09.2009","article-title":"Visual impairment in the absence of dystroglycan","volume":"29","author":"Satz","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2010.11.056_bib0145","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/BF00267828","article-title":"Colocalization of retinal dystrophin and actin in postsynaptic dendrites of rod and cone photoreceptor synapses","volume":"100","author":"Schmitz","year":"1993","journal-title":"Histochemistry"},{"key":"10.1016\/j.neulet.2010.11.056_bib0150","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1083\/jcb.200105003","article-title":"A stoichiometric complex of neurexins and dystroglycan in brain","volume":"154","author":"Sugita","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neulet.2010.11.056_bib0155","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1093\/hmg\/ddg153","article-title":"Fukutin is required for maintenance of muscle integrity, cortical histiogenesis and normal eye development","volume":"12","author":"Takeda","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neulet.2010.11.056_bib0160","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/12703","article-title":"Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety","volume":"23","author":"Tronche","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neulet.2010.11.056_bib0165","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/002215549804600207","article-title":"Beta-dystroglycan localization in the photoreceptor and Muller cells in the rat retina revealed by immunoelectron microscopy","volume":"46","author":"Ueda","year":"1998","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.neulet.2010.11.056_bib0170","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S1534-5807(01)00070-3","article-title":"Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1","volume":"1","author":"Yoshida","year":"2001","journal-title":"Dev. Cell"},{"key":"10.1016\/j.neulet.2010.11.056_bib0175","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1126\/science.1180512","article-title":"O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding","volume":"327","author":"Yoshida-Moriguchi","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.neulet.2010.11.056_bib0180","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1042\/0264-6021:3610153","article-title":"Cloning and expression of a novel UDP-GlcNAc:alpha-d-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-d-mannoside beta1,2-N-acetylglucosaminyltransferase I","volume":"361","author":"Zhang","year":"2002","journal-title":"Biochem. J."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394010015107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394010015107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T18:56:09Z","timestamp":1559847369000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394010015107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0304394010015107"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2010.11.056","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}