{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:04:17Z","timestamp":1791212657581,"version":"4.1.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.neulet.2011.10.040","type":"journal-article","created":{"date-parts":[[2011,10,25]],"date-time":"2011-10-25T16:11:06Z","timestamp":1319559066000},"page":"279-281","source":"Crossref","is-referenced-by-count":29,"title":["Optineurin with amyotrophic lateral sclerosis-related mutations abrogates inhibition of interferon regulatory factor-3 activation"],"prefix":"10.1016","volume":"505","author":[{"given":"Takemasa","family":"Sakaguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Irie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryoko","family":"Kawabata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asuka","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Maruyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideshi","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2011.10.040_bib0005","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.cell.2006.02.015","article-title":"Pathogen recognition and innate immunity","volume":"124","author":"Akira","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.neulet.2011.10.040_bib0010","doi-asserted-by":"crossref","first-page":"17264","DOI":"10.1073\/pnas.0407639101","article-title":"The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter","volume":"101","author":"Andrejeva","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neulet.2011.10.040_bib0015","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1038\/emboj.2010.50","article-title":"Viral apoptosis is induced by IRF-3-mediated activation of Bax","volume":"29","author":"Chattopadhyay","year":"2010","journal-title":"EMBO J."},{"key":"10.1016\/j.neulet.2011.10.040_bib0020","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/ana.22149","article-title":"Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis","volume":"69","author":"Douville","year":"2011","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neulet.2011.10.040_bib0025","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/ng1742","article-title":"ANG mutations segregate with familial and sporadic amyotrophic lateral sclerosis","volume":"38","author":"Greenway","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neulet.2011.10.040_bib0030","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1128\/JVI.02218-06","article-title":"The YLDL sequence within Sendai virus M protein is critical for budding of virus-like particles and interacts with Alix\/AIP1 independently of C protein","volume":"81","author":"Irie","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.neulet.2011.10.040_bib0035","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/ni1303","article-title":"Innate immune recognition of viral infection","volume":"7","author":"Kawai","year":"2006","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.neulet.2011.10.040_bib0040","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.micinf.2007.03.014","article-title":"Bovine parainfluenza virus type 3 accessory proteins that suppress beta interferon production","volume":"9","author":"Komatsu","year":"2007","journal-title":"Microbes Infect."},{"key":"10.1016\/j.neulet.2011.10.040_bib0045","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1126\/science.1166066","article-title":"Mutations in the FUS\/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis","volume":"323","author":"Kwiatkowski","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.neulet.2011.10.040_bib0050","first-page":"249","article-title":"Amyotrophic lateral sclerosis","volume":"vol. 82","author":"Leigh","year":"2007"},{"key":"10.1016\/j.neulet.2011.10.040_bib0055","doi-asserted-by":"crossref","first-page":"e1000778","DOI":"10.1371\/journal.ppat.1000778","article-title":"Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection","volume":"6","author":"Mankouri","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.neulet.2011.10.040_bib0060","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nature08971","article-title":"Mutations of optineurin in amyotrophic lateral sclerosis","volume":"465","author":"Maruyama","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2011.10.040_bib0065","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0378-1119(91)90434-D","article-title":"Efficient selection for high-expression transfectants with a novel eukaryotic vector","volume":"108","author":"Niwa","year":"1991","journal-title":"Gene"},{"key":"10.1016\/j.neulet.2011.10.040_bib0070","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1126\/science.1066901","article-title":"Adult-onset primary open-angle glaucoma caused by mutations in optineurin","volume":"295","author":"Rezaie","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.neulet.2011.10.040_bib0075","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/362059a0","article-title":"Mutations in Cu\/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis","volume":"362","author":"Rosen","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2011.10.040_bib0080","doi-asserted-by":"crossref","DOI":"10.1111\/j.1348-0421.2011.00379.x","article-title":"Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5","author":"Sakaguchi","year":"2011","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.neulet.2011.10.040_bib0085","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1126\/science.1154584","article-title":"TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis","volume":"319","author":"Sreedharan","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.neulet.2011.10.040_bib0090","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1126\/science.1165942","article-title":"Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6","volume":"323","author":"Vance","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.neulet.2011.10.040_bib0095","doi-asserted-by":"crossref","first-page":"6668","DOI":"10.4049\/jimmunol.169.12.6668","article-title":"Cutting edge: a novel Toll\/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling","volume":"169","author":"Yamamoto","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.neulet.2011.10.040_bib0100","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/ni1087","article-title":"The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses","volume":"5","author":"Yoneyama","year":"2004","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.neulet.2011.10.040_bib0105","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.cub.2007.07.041","article-title":"Optineurin negatively regulates TNFalpha-induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP","volume":"17","author":"Zhu","year":"2007","journal-title":"Curr. Biol."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394011014388?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394011014388?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T01:24:14Z","timestamp":1543454654000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394011014388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0304394011014388"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2011.10.040","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}