{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T21:31:55Z","timestamp":1781559115737,"version":"3.54.5"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.neulet.2012.08.084","type":"journal-article","created":{"date-parts":[[2012,9,7]],"date-time":"2012-09-07T16:31:53Z","timestamp":1347035513000},"page":"148-152","source":"Crossref","is-referenced-by-count":18,"title":["Hyper-phosphorylation of GSK-3\u03b2: Possible roles in chlorpyrifos-induced behavioral alterations in animal model of depression"],"prefix":"10.1016","volume":"528","author":[{"given":"Wen-Qiang","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Ming","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Zhi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2012.08.084_bib0005","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1289\/ehp.7867","article-title":"Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression","volume":"113","author":"Aldridge","year":"2005","journal-title":"Environmental Health Perspectives"},{"key":"10.1016\/j.neulet.2012.08.084_bib0010","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.taap.2004.08.002","article-title":"Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions","volume":"203","author":"Aldridge","year":"2005","journal-title":"Toxicology and Applied Pharmacology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0015","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1289\/ehp.6489","article-title":"Serotonergic systems targeted by developmental exposure to chlorpyrifos: effects during different critical periods","volume":"111","author":"Aldridge","year":"2003","journal-title":"Environmental Health Perspectives"},{"key":"10.1016\/j.neulet.2012.08.084_bib0020","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1289\/ehp.6713","article-title":"Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling","volume":"112","author":"Aldridge","year":"2004","journal-title":"Environmental Health Perspectives"},{"key":"10.1016\/j.neulet.2012.08.084_bib0025","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0920-9964(01)00376-0","article-title":"An investigation of the Wnt-signalling pathway in the prefrontal cortex in schizophrenia, bipolar disorder and major depressive disorder","volume":"58","author":"Beasley","year":"2002","journal-title":"Schizophrenia Research"},{"key":"10.1016\/j.neulet.2012.08.084_bib0030","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1097\/01.jom.0000235938.70212.dd","article-title":"Depression and pesticide exposures in female spouses of licensed pesticide applicators in the agricultural health study cohort","volume":"48","author":"Beseler","year":"2006","journal-title":"Journal of Occupational and Environmental Medicine"},{"key":"10.1016\/j.neulet.2012.08.084_bib0035","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1124\/mol.111.071092","article-title":"Glycogen synthase kinase-3beta is a functional modulator of serotonin-1B receptors","volume":"79","author":"Chen","year":"2011","journal-title":"Molecular Pharmacology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0040","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.neuro.2011.03.008","article-title":"Repeated exposure to chlorpyrifos alters the performance of adolescent male rats in animal models of depression and anxiety","volume":"32","author":"Chen","year":"2011","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0045","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/378785a0","article-title":"Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B","volume":"378","author":"Cross","year":"1995","journal-title":"Nature"},{"issue":"Suppl. 2","key":"10.1016\/j.neulet.2012.08.084_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10408440802272158","article-title":"Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment","volume":"38","author":"Eaton","year":"2008","journal-title":"Critical Reviews in Toxicology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0055","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.3233\/JAD-2010-100687","article-title":"LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3beta in vivo and in vitro","volume":"21","author":"Fu","year":"2010","journal-title":"Journal of Alzheimer's Disease"},{"key":"10.1016\/j.neulet.2012.08.084_bib0060","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/sj.mp.4001518","article-title":"Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers","volume":"9","author":"Gould","year":"2004","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.neulet.2012.08.084_bib0065","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0301-0082(01)00011-9","article-title":"The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling","volume":"65","author":"Grimes","year":"2001","journal-title":"Progress in Neurobiology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0070","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.neuroimage.2010.02.065","article-title":"Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression","volume":"53","author":"Inkster","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.neulet.2012.08.084_bib0075","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1289\/ehp.8750","article-title":"Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells","volume":"114","author":"Jameson","year":"2006","journal-title":"Environmental Health Perspectives"},{"key":"10.1016\/j.neulet.2012.08.084_bib0080","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.biopsych.2004.01.008","article-title":"Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus","volume":"55","author":"Kaidanovich-Beilin","year":"2004","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.neulet.2012.08.084_bib0085","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jad.2011.09.024","article-title":"Protein levels of beta-catenin and activation state of glycogen synthase kinase-3beta in major depression. A study with postmortem prefrontal cortex","volume":"136","author":"Karege","year":"2012","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.neulet.2012.08.084_bib0090","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/nature07455","article-title":"The molecular neurobiology of depression","volume":"455","author":"Krishnan","year":"2008","journal-title":"Nature"},{"issue":"Suppl. 3","key":"10.1016\/j.neulet.2012.08.084_bib0095","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1289\/ehp.99107s3431","article-title":"Pesticides and inner-city children: exposures, risks, and prevention","volume":"107","author":"Landrigan","year":"1999","journal-title":"Environmental Health Perspectives"},{"key":"10.1016\/j.neulet.2012.08.084_bib0100","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.neulet.2010.10.076","article-title":"Small molecule GSK-3 inhibitors increase neurogenesis of human neural progenitor cells","volume":"488","author":"Lange","year":"2011","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.neulet.2012.08.084_bib0105","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1007\/s007020050235","article-title":"Glycogen synthase kinase-3beta, beta-catenin, and tau in postmortem bipolar brain","volume":"106","author":"Lesort","year":"1999","journal-title":"Journal of Neural Transmission"},{"key":"10.1016\/j.neulet.2012.08.084_bib0110","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1146\/annurev.cellbio.20.010403.113126","article-title":"The Wnt signaling pathway in development and disease","volume":"20","author":"Logan","year":"2004","journal-title":"Annual Review of Cell and Developmental Biology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0115","doi-asserted-by":"crossref","first-page":"202","DOI":"10.4306\/pi.2010.7.3.202","article-title":"Increased glycogen synthase kinase-3beta mRNA level in the hippocampus of patients with major depression: a study using the Stanley neuropathology consortium integrative database","volume":"7","author":"Oh","year":"2010","journal-title":"Psychiatry Investigation"},{"key":"10.1016\/j.neulet.2012.08.084_bib0120","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.biopsych.2010.04.023","article-title":"Wnt2 expression and signaling is increased by different classes of antidepressant treatments","volume":"68","author":"Okamoto","year":"2010","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.neulet.2012.08.084_bib0125","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.brainresbull.2004.07.005","article-title":"Alpha7 nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: nicotine and chlorpyrifos","volume":"64","author":"Slotkin","year":"2004","journal-title":"Brain Research Bulletin"},{"key":"10.1016\/j.neulet.2012.08.084_bib0130","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00204-008-0346-2","article-title":"Subtoxic chlorpyrifos treatment resulted in differential expression of genes implicated in neurological functions and development","volume":"83","author":"Stapleton","year":"2009","journal-title":"Archives of Toxicology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0135","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.intimp.2012.06.015","article-title":"Glycogen synthase kinase-3beta regulates anti-inflammatory property of fluoxetine","volume":"14","author":"Su","year":"2012","journal-title":"International Immunopharmacology"},{"key":"10.1016\/j.neulet.2012.08.084_bib0140","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.neulet.2008.10.065","article-title":"Aquaporin 4 deficiency modulates morphine pharmacological actions","volume":"448","author":"Wu","year":"2008","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.neulet.2012.08.084_bib0145","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.pnpbp.2009.12.009","article-title":"Association between glycogen synthase kinase-3beta gene polymorphisms and major depression and suicidal behavior in a Korean population","volume":"34","author":"Yoon","year":"2010","journal-title":"Progress in Neuro-psychopharmacology & Biological Psychiatry"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394012011780?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394012011780?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T00:26:23Z","timestamp":1542759983000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394012011780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0304394012011780"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2012.08.084","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}