{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:30:21Z","timestamp":1759530621575},"reference-count":35,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.neulet.2013.05.065","type":"journal-article","created":{"date-parts":[[2013,6,10]],"date-time":"2013-06-10T02:49:53Z","timestamp":1370832593000},"page":"191-196","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Meta-analysis confirms a functional polymorphism (5-HTTLPR) in the serotonin transporter gene conferring risk of bipolar disorder in European populations"],"prefix":"10.1016","volume":"549","author":[{"given":"Hong-yan","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiu-feng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-ling","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2013.05.065_bib0005","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/BF00805795","article-title":"The epidemiology of bipolar affective disorder","volume":"30","author":"Bebbington","year":"1995","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"key":"10.1016\/j.neulet.2013.05.065_bib0010","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0304-3940(98)00677-6","article-title":"Serotonin transporter gene polymorphisms in patients with unipolar or bipolar depression","volume":"255","author":"Bellivier","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2013.05.065_bib0015","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/sj.mp.4001663","article-title":"Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysis","volume":"10","author":"Cho","year":"2005","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0020","first-page":"453","article-title":"A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders","volume":"1","author":"Collier","year":"1996","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0025","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/YPG.0b013e3283539517","article-title":"Association between 5HTT, DAT1, and DRD4 and bipolar disorder in youth","volume":"22","author":"Cosgrove","year":"2012","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0030","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1034\/j.1399-5618.2001.30604.x","article-title":"Association studies of bipolar disorder","volume":"3","author":"Craddock","year":"2001","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neulet.2013.05.065_bib0035","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1136\/jmg.36.8.585","article-title":"Genetics of bipolar disorder","volume":"36","author":"Craddock","year":"1999","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0040","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/0197-2456(90)90005-M","article-title":"Power and sample size calculations. A review and computer program","volume":"11","author":"Dupont","year":"1990","journal-title":"Control. Clin. Trials"},{"key":"10.1016\/j.neulet.2013.05.065_bib0045","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.neulet.2013.05.065_bib0050","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/(SICI)1096-8628(19980207)81:1<58::AID-AJMG11>3.0.CO;2-V","article-title":"Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders","volume":"81","author":"Furlong","year":"1998","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0055","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0006-3223(97)00540-4","article-title":"Serotonin transporter gene and risk for bipolar affective disorder: an association study in Spanish population","volume":"43","author":"Gutierrez","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0060","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0924-9338(03)00026-9","article-title":"Association analysis of the insertion\/deletion polymorphism in serotonin transporter gene in patients with affective disorder","volume":"18","author":"Hauser","year":"2003","journal-title":"Eur. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1096-8628(19980207)81:1<1::AID-AJMG1>3.0.CO;2-2","article-title":"Serotonin transporter (5-HTT) gene polymorphisms are not associated with susceptibility to mood disorders","volume":"81","author":"Hoehe","year":"1998","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0070","first-page":"19","article-title":"Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy","volume":"5","author":"Kenna","year":"2012","journal-title":"Pharmgenomics Pers. Med."},{"key":"10.1016\/j.neulet.2013.05.065_bib0075","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1176\/appi.ajp.161.10.1814","article-title":"High concordance of bipolar I disorder in a nationwide sample of twins","volume":"161","author":"Kieseppa","year":"2004","journal-title":"Am. J. Psychiatry."},{"key":"10.1016\/j.neulet.2013.05.065_bib0080","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/ajmg.b.30104","article-title":"Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders","volume":"133B","author":"Lasky-Su","year":"2005","journal-title":"Am. J. Med. Genet. B: Neuropsychiatr. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0085","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1126\/science.274.5292.1527","article-title":"Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region","volume":"274","author":"Lesch","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.neulet.2013.05.065_bib0090","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/01.ypg.0000180684.26288.d7","article-title":"Serotonin transporter linked promoter (polymorphism) in the serotonin transporter gene may be associated with antidepressant-induced mania in bipolar disorder","volume":"16","author":"Masoliver","year":"2006","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0095","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1034\/j.1600-0447.2001.00173.x","article-title":"Platelet serotonin transporters and the transporter gene in control subjects, unipolar patients and bipolar patients","volume":"103","author":"Mellerup","year":"2001","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.neulet.2013.05.065_bib0100","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/(SICI)1096-8628(19980508)81:3<225::AID-AJMG4>3.0.CO;2-V","article-title":"Analysis of a novel functional polymorphism within the promoter region of the serotonin transporter gene (5-HTT) in Brazilian patients affected by bipolar disorder and schizophrenia","volume":"81","author":"Mendes de Oliveira","year":"1998","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0105","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/sj.ejhg.5201149","article-title":"Serotonin transporter 5HTTLPR polymorphism and affective disorders: no evidence of association in a large European multicenter study","volume":"12","author":"Mendlewicz","year":"2004","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0110","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0140-6736(02)07450-0","article-title":"Bipolar disorder","volume":"359","author":"Muller-Oerlinghausen","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.neulet.2013.05.065_bib0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2013.02.006","article-title":"Worldwide population variation and haplotype analysis at the serotonin transporter gene SLC6A4 and implications for association studies","author":"Murdoch","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0120","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1002\/1096-8628(20001204)96:6<845::AID-AJMG30>3.0.CO;2-R","article-title":"Multimarkerhaplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder","volume":"96","author":"Mynett-Johnson","year":"2000","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0125","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/ajmg.b.30563","article-title":"Is the 5-HTTLPR polymorphism associated with bipolar disorder or with suicidal behavior of bipolar disorder patients?","volume":"147B","author":"Neves","year":"2008","journal-title":"Am. J. Med. Genet. B: Neuropsychiatr. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0130","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/sj.mp.4000725","article-title":"Analysis of the serotonin transporter polymorphism (5-HTTLPR) in Brazilian patients affected by dysthymia, major depression and bipolar disorder","volume":"5","author":"Oliveira","year":"2000","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0135","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0304-3940(00)01464-6","article-title":"An association study of bipolar mood disorder (type I) with the 5-HTTLPR serotonin transporter polymorphism in a human population isolate from Colombia","volume":"292","author":"Ospina-Duque","year":"2000","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2013.05.065_bib0140","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/sj.mp.4000256","article-title":"Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT)","volume":"2","author":"Rees","year":"1997","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0145","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1176\/appi.ajp.159.1.23","article-title":"Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder","volume":"159","author":"Rotondo","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0150","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/sj.mp.4001421","article-title":"Examination of G72 and d-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder","volume":"9","author":"Schumacher","year":"2004","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0155","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/sj.mp.4000936","article-title":"Serotonin transporter gene (5-HTTLPR) and major psychoses","volume":"7","author":"Serretti","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neulet.2013.05.065_bib0160","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1038\/npp.2008.204","article-title":"Role of variation in the serotonin transporter protein gene (SLC6A4) in trait disturbances in the ventral anterior cingulate in bipolar disorder","volume":"34","author":"Shah","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neulet.2013.05.065_bib0165","first-page":"1712","article-title":"Polymorphism in the human serotonin transporter gene in endogenous psychoses","volume":"36","author":"Shcherbatykh","year":"2000","journal-title":"Genetika"},{"key":"10.1016\/j.neulet.2013.05.065_bib0170","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1097\/01.ypg.0000218623.03752.e4","article-title":"No allelic association or interaction of three known functional polymorphisms with bipolar disorder in a northern Swedish isolated population","volume":"16","author":"Van Den Bogaert","year":"2006","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.neulet.2013.05.065_bib0175","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1399-5618.2008.00603.x","article-title":"Association between brain-derived neurotrophic factor gene and a severe form of bipolar disorder, but no interaction with the serotonin transporter gene","volume":"10","author":"Vincze","year":"2008","journal-title":"Bipolar Disord."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394013005223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394013005223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T01:17:44Z","timestamp":1563153464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394013005223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":35,"alternative-id":["S0304394013005223"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2013.05.065","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Meta-analysis confirms a functional polymorphism (5-HTTLPR) in the serotonin transporter gene conferring risk of bipolar disorder in European populations","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2013.05.065","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}