{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:22:16Z","timestamp":1791861736779,"version":"4.3.4"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000864","name":"Michael J. Fox Foundation for Parkinson's Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000864","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001512","name":"National Brain and Tissue Resource for Parkinson's Disease and Related Disorders","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001512","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Arizona Alzheimer's Disease Core Center"},{"DOI":"10.13039\/100006504","name":"Arizona Department of Health Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006504","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008335","name":"Arizona Biomedical Research Commission","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008335","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.neulet.2014.04.027","type":"journal-article","created":{"date-parts":[[2014,4,28]],"date-time":"2014-04-28T20:31:42Z","timestamp":1398717102000},"page":"34-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":140,"special_numbering":"C","title":["Phosphorylated \u03b1-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects"],"prefix":"10.1016","volume":"571","author":[{"given":"Thomas G.","family":"Beach","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremiah","family":"Carew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geidy","family":"Serrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles H.","family":"Adler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly A.","family":"Shill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia I.","family":"Sue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwan N.","family":"Sabbagh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Akiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00e1s","family":"Cuenca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2014.04.027_bib0005","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.80.7_supplement.P04.143","article-title":"Abnormal variable contrast acuity in Parkinson's disease","volume":"80","author":"Lin","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.neulet.2014.04.027_bib0010","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.1600-0404.1997.tb00286.x","article-title":"Distorted colour discrimination in Parkinson's disease is related to severity of the disease","volume":"96","author":"Muller","year":"1997","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.neulet.2014.04.027_bib0015","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/BF02252618","article-title":"Disturbance of colour perception in Parkinson's disease","volume":"6","author":"Buttner","year":"1993","journal-title":"J. Neural Transm. Park. Dis. Dement. Sect."},{"key":"10.1016\/j.neulet.2014.04.027_bib0020","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1002\/mds.23891","article-title":"Visual symptoms in Parkinson's disease and Parkinson's disease dementia","volume":"26","author":"Archibald","year":"2011","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neulet.2014.04.027_bib0025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/mds.25741","article-title":"Venturing into the no-man's land of the retina in Parkinson's disease","volume":"29","author":"Bodis-Wollner","year":"2014","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neulet.2014.04.027_bib0030","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/ICU.0000000000000000","article-title":"The contribution of optical coherence tomography in neurodegenerative diseases","volume":"24","author":"Simao","year":"2013","journal-title":"Curr. Opin. Ophthalmol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0035","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00401-009-0538-8","article-title":"Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction","volume":"117","author":"Beach","year":"2009","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0040","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/cne.20761","article-title":"Morphological impairments in retinal neurons of the scotopic visual pathway in a monkey model of Parkinson's disease","volume":"493","author":"Cuenca","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0045","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.nbd.2011.06.009","article-title":"Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina","volume":"44","author":"Esteve-Rudd","year":"2011","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neulet.2014.04.027_bib0050","first-page":"949","article-title":"Alpha synuclein gene expression profile in the retina of vertebrates","volume":"13","author":"Martinez-Navarrete","year":"2007","journal-title":"Mol. Vis."},{"key":"10.1016\/j.neulet.2014.04.027_bib0055","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/NEN.0b013e31820376cc","article-title":"Protein aggregation in the aging retina","volume":"70","author":"Leger","year":"2011","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0060","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/ana.10730","article-title":"Retinal involvement in dementia with Lewy bodies: a clue to hallucinations?","volume":"54","author":"Maurage","year":"2003","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0065","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/bpa.12070","article-title":"Beta-amyloid, phospho-tau and alpha-synuclein deposits similar to those in the brain are not identified in the eyes of Alzheimer's and Parkinson's disease patients","volume":"24","author":"Ho","year":"2014","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0070","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s10561-008-9067-2","article-title":"The Sun Health Research Institute Brain Donation Program: description and experience, 1987\u20132007","volume":"9","author":"Beach","year":"2008","journal-title":"Cell Tissue Bank"},{"key":"10.1016\/j.neulet.2014.04.027_bib0075","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1001\/archneur.56.1.33","article-title":"Diagnostic criteria for Parkinson disease","volume":"56","author":"Gelb","year":"1999","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0080","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1212\/01.wnl.0000187889.17253.b1","article-title":"Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium","volume":"65","author":"McKeith","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.neulet.2014.04.027_bib0085","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0197-4580(97)00057-2","article-title":"Consensus recommendations for the postmortem diagnosis of Alzheimer's disease","volume":"18","year":"1997","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neulet.2014.04.027_bib0090","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1212\/WNL.44.11.2015","article-title":"Preliminary NINDS neuropathologic criteria for Steele\u2013Richardson\u2013Olszewski syndrome (progressive supranuclear palsy)","volume":"44","author":"Hauw","year":"1994","journal-title":"Neurology"},{"key":"10.1016\/j.neulet.2014.04.027_bib0095","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1750-3639.2007.00054.x","article-title":"Progressive supranuclear palsy: pathology and genetics","volume":"17","author":"Dickson","year":"2007","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0100","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1159\/000332802","article-title":"The retinal wholemount technique: a window to understanding the brain and behaviour","volume":"79","author":"Ullmann","year":"2012","journal-title":"Brain Behav. Evol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0105","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/cne.903320403","article-title":"Immunocytochemical staining of AII-amacrine cells in the rat retina with antibodies against parvalbumin","volume":"332","author":"Wassle","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0110","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.expneurol.2007.11.019","article-title":"Relationship of phosphorylated alpha-synuclein and tau accumulation to Abeta deposition in the cerebral cortex of dementia with Lewy bodies","volume":"210","author":"Obi","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0115","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s00401-008-0409-8","article-title":"Evaluation of alpha-synuclein immunohistochemical methods used by invited experts","volume":"116","author":"Beach","year":"2008","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0120","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.expneurol.2012.11.020","article-title":"Changes in properties of serine 129 phosphorylated alpha-synuclein with progression of Lewy-type histopathology in human brains","volume":"240","author":"Walker","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0125","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/ncb748","article-title":"Alpha-synuclein is phosphorylated in synucleinopathy lesions","volume":"4","author":"Fujiwara","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0130","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00401-010-0664-3","article-title":"Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders","volume":"119","author":"Beach","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0135","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1097\/NEN.0b013e3182805c72","article-title":"Submandibular gland biopsy for the diagnosis of Parkinson disease","volume":"72","author":"Beach","year":"2013","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0140","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1080\/02713680600776119","article-title":"Retinopetal axons in mammals: emphasis on histamine and serotonin","volume":"31","author":"Gastinger","year":"2006","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.neulet.2014.04.027_bib0145","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0165-3806(01)00103-1","article-title":"Confirmation of the retinopetal\/centrifugal nature of the tyrosine hydroxylase-immunoreactive fibers of the retina and optic nerve in the weaver mouse","volume":"127","author":"Simon","year":"2001","journal-title":"Brain Res. Dev. Brain Res."},{"issue":"Suppl 2","key":"10.1016\/j.neulet.2014.04.027_bib0150","first-page":"II3","article-title":"Pathoanatomy of Parkinson's disease","volume":"247","author":"Braak","year":"2000","journal-title":"J. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0155","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/cne.903180204","article-title":"Neurons of the human retina: a Golgi study","volume":"318","author":"Kolb","year":"1992","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neulet.2014.04.027_bib0160","doi-asserted-by":"crossref","first-page":"16094","DOI":"10.1523\/JNEUROSCI.4132-11.2011","article-title":"Melanopsin-positive intrinsically photosensitive retinal ganglion cells: from form to function","volume":"31","author":"Schmidt","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2014.04.027_bib0165","doi-asserted-by":"crossref","first-page":"659","DOI":"10.3233\/JAD-121975","article-title":"Retinal nerve fiber layer thinning in dementia associated with Parkinson's disease, dementia with Lewy bodies, and Alzheimer's disease","volume":"34","author":"Moreno-Ramos","year":"2013","journal-title":"J. Alzheimers. Dis."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394014003309?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394014003309?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T06:48:22Z","timestamp":1716706102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394014003309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":33,"alternative-id":["S0304394014003309"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2014.04.027","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phosphorylated \u03b1-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2014.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}