{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T04:57:39Z","timestamp":1785473859634,"version":"3.56.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Korea Health Technology R&D Project through the Korea Health Industry Development Institute","award":["KHIDI"],"award-info":[{"award-number":["KHIDI"]}]},{"name":"Ministry of Health & Welfare, Republic of Korea","award":["HI15C1535"],"award-info":[{"award-number":["HI15C1535"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.neulet.2017.02.030","type":"journal-article","created":{"date-parts":[[2017,2,13]],"date-time":"2017-02-13T15:23:20Z","timestamp":1486999400000},"page":"111-120","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Adenovirus vector-mediated ex vivo gene transfer of brain-derived neurotrophic factor (BDNF) tohuman umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) promotescrush-injured rat sciatic nerve regeneration"],"prefix":"10.1016","volume":"643","author":[{"given":"Wei-hong","family":"Hei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akram A.","family":"Almansoori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi-Ae","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Won","family":"Ju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nari","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bong-Ju","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soung-Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Won","family":"Jahng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2017.02.030_bib0005","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1007\/s00701-011-1054-x","article-title":"Effects of combining electrical stimulation with BDNF gene transfer on the regeneration of crushed rat sciatic nerve","volume":"153","author":"Alrashdan","year":"2011","journal-title":"Acta Neurochir."},{"key":"10.1016\/j.neulet.2017.02.030_bib0010","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0301-0082(98)00028-8","article-title":"Adenovirus in the brain: recent advances of gene therapy for neurodegenerative diseases","volume":"55","author":"Barkats","year":"1998","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neulet.2017.02.030_bib0015","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1006\/exnr.1999.7204","article-title":"Adenoviral vector-mediated expression of a foreign gene in peripheral nerve tissue bridges implanted in the injured peripheral and central nervous system","volume":"160","author":"Blits","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.02.030_bib0020","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1046\/j.1440-1789.2002.00450.x","article-title":"Ischemic rat brain extracts induce human marrow stromal cell growth factor production","volume":"22","author":"Chen","year":"2002","journal-title":"Neuropathology"},{"key":"10.1016\/j.neulet.2017.02.030_bib0025","first-page":"947","article-title":"Effect of adenovirus expressing NGF on sciatic nerve injury in rats","volume":"23","author":"Chen","year":"2009","journal-title":"Chin. J. Reparat. Reconstruct. Surg."},{"key":"10.1016\/j.neulet.2017.02.030_bib0030","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.expneurol.2005.10.029","article-title":"Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis","volume":"198","author":"Crigler","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.02.030_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/scrt148","article-title":"Umbilical cord blood-derived mesenchymal stem cells consist of a unique population of progenitors co-expressing mesenchymal stem cell and neuronal markers capable of instantaneous neuronal differentiation","volume":"3","author":"Divya","year":"2012","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.neulet.2017.02.030_bib0040","doi-asserted-by":"crossref","first-page":"066011","DOI":"10.1088\/1741-2560\/13\/6\/066011","article-title":"BDNF gene delivery within and beyond templated agarose multi-channel guidance scaffolds enhances peripheral nerve regeneration","volume":"13","author":"Gao","year":"2016","journal-title":"J. Neural Eng."},{"key":"10.1016\/j.neulet.2017.02.030_bib0045","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3325\/cmj.2009.50.351","article-title":"Human umbilical cord bloodderived stromal cells suppress xenogeneic immune cell response in vitro","volume":"50","author":"Hao","year":"2009","journal-title":"Croat. Med. J."},{"key":"10.1016\/j.neulet.2017.02.030_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/00207454.2015.1054032","article-title":"Effects of electromagnetic field (PEMF) exposure at different frequency and duration on the peripheral nerve regeneration: in vitro and in vivo study","author":"Hei","year":"2015","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.neulet.2017.02.030_bib0055","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/bem.21966","article-title":"Schwann-like cells differentiated from human dental pulp stem cells combined with a pulsed electromagnetic field can improve peripheral nerve regeneration","volume":"37","author":"Hei","year":"2016","journal-title":"Bioelectromagnetics"},{"key":"10.1016\/j.neulet.2017.02.030_bib0060","doi-asserted-by":"crossref","first-page":"337","DOI":"10.55782\/ane-2010-1806","article-title":"Transplantation of neural stem cells derived from human cord blood to the brain of adult and neonatal rats","volume":"70","author":"Jablonska","year":"2010","journal-title":"Acta Neurobiol. Exp. (Wars)"},{"key":"10.1016\/j.neulet.2017.02.030_bib0065","doi-asserted-by":"crossref","first-page":"774","DOI":"10.3109\/00207454.2014.971121","article-title":"Co-treatment effect of pulsed electromagnetic field (PEMF) with human dental pulp stromal cells and FK506 on the regeneration of crush injured rat sciatic nerve","volume":"125","author":"Kim","year":"2015","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.neulet.2017.02.030_bib0070","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1089\/089771504322972112","article-title":"Adenovirus vector-mediated in vivo gene transfer of brain-derived neurotrophic factor (BDNF) promotes rubrospinal axonal regeneration and functional recovery after complete transection of the adult rat spinal cord","volume":"21","author":"Koda","year":"2004","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2017.02.030_bib0075","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1007\/s00586-007-0499-3","article-title":"Adenovirus vector-mediated ex vivo gene transfer of brain-derived neurotrophic factor to bone marrow stromal cells promotes axonal regeneration after transplantation in completely transected adult rat spinal cord","volume":"16","author":"Koda","year":"2007","journal-title":"Eur. Spine J."},{"key":"10.1016\/j.neulet.2017.02.030_bib0080","first-page":"218","article-title":"Human umbilical cord blood-derived mesenchymal stem cells ameliorate psoriasis-like skin inflammation in mice","volume":"9","author":"Lee","year":"2017","journal-title":"Biochem. Biophys. Rep."},{"key":"10.1016\/j.neulet.2017.02.030_bib0085","first-page":"e26","article-title":"Recombinant human nerve growth factor (rhNGF-\u03b2) gene transfer promotes regeneration of crush-injured mental nerve in rats","volume":"113","author":"Li","year":"2012","journal-title":"Oral Surg. Oral Med."},{"key":"10.1016\/j.neulet.2017.02.030_bib0090","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1159\/000233255","article-title":"Therapeutic benefit of human umbilical cord derived mesenchymal stromal cells in intracerebral hemorrhage rat: implications of anti-inflammation and angiogenesis","volume":"24","author":"Liao","year":"2009","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.neulet.2017.02.030_bib0095","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.3727\/096368910X557236","article-title":"Neural differentiation of brain-derived neurotrophic factor-expressing human umbilical cord blood-derived mesenchymal stem cells in culture via TrkB-mediated ERK and \u03b2-catenin phosphorylation and following transplantation into the developing brain","volume":"20","author":"Lim","year":"2011","journal-title":"Cell Transplant."},{"key":"10.1016\/j.neulet.2017.02.030_bib0100","doi-asserted-by":"crossref","first-page":"e17899","DOI":"10.1371\/journal.pone.0017899","article-title":"Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these cells promotes nerve healing and axon growth de novo","volume":"6","author":"Lopatina","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.neulet.2017.02.030_bib0105","article-title":"Transplantation of mesenchymal stem cells from human umbilical cord versus human umbilical cord blood for peripheral nerve regeneration","volume":"5","author":"Pang","year":"2010","journal-title":"Neurual Regenerat. Res."},{"key":"10.1016\/j.neulet.2017.02.030_bib0110","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.1016\/j.biomaterials.2009.05.057","article-title":"Mesenchymal stem cell differentiation to neuronal cells on electrospun nanofibrous substrates for nerve tissue engineering","volume":"30","author":"Prabhakaran","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.neulet.2017.02.030_bib0115","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.3727\/096368910X545086","article-title":"Human umbilical cord blood-derived mesenchymal stem cells protect against neuronal cell death and ameliorate motor deficits in Niemann Pick type C1 mice","volume":"20","author":"Seo","year":"2011","journal-title":"Cell Transplant."},{"key":"10.1016\/j.neulet.2017.02.030_bib0120","first-page":"2018","article-title":"Human umbilical cord blood-derived mesenchymal stem cells promote regeneration of crush-injured rat sciatic nerves","volume":"7","author":"Sung","year":"2012","journal-title":"Neurual Regenerat. Res."},{"key":"10.1016\/j.neulet.2017.02.030_bib0125","doi-asserted-by":"crossref","first-page":"e44592","DOI":"10.1371\/journal.pone.0044592","article-title":"Brain-derived neurotrophic factor from bone marrow-derived cells promotes post-injury repair of peripheral nerve","volume":"7","author":"Takemura","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neulet.2017.02.030_bib0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1469-7580.1999.19410001.x","article-title":"Peripheral nerve regeneration and neurotrophic factors","volume":"194","author":"Terenghi","year":"1999","journal-title":"J. Anat."},{"key":"10.1016\/j.neulet.2017.02.030_bib0135","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.expneurol.2012.09.011","article-title":"Exogenous BDNF enhances the integration of chronically injured axons that regenerate through a peripheral nerve grafted into a chondroitinase-treated spinal cord injury site","volume":"239","author":"Tom","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.02.030_bib0140","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3109\/00207454.2013.828055","article-title":"Regulation and direction of umbilical cord blood mesenchymal stem cells to adopt neuronal fate","volume":"124","author":"Wang","year":"2014","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.neulet.2017.02.030_bib0145","first-page":"76","article-title":"Umbilical cord mesenchymal stem cell transplantation significantly improves neurological function in patients with sequelae of traumatic brain injury","volume":"2013","author":"Wang","year":"1532","journal-title":"Brain Res."},{"key":"10.1016\/j.neulet.2017.02.030_bib0150","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ijdevneu.2014.06.014","article-title":"Umbilical cord blood mesenchymal stem cells co-modified by TERT and BDNF: A novel neuroprotective therapy for neonatal hypoxic-ischemic brain damage","volume":"38","author":"Zhao","year":"2014","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.neulet.2017.02.030_bib0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neulet.2016.04.006","article-title":"BDNF promotes the axonal regrowth after sciatic nerve crush through intrinsic neuronal capability upregulation and distal portion protection","volume":"621","author":"Zheng","year":"2016","journal-title":"Neurosci. Lett."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394017301362?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394017301362?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T12:56:15Z","timestamp":1719060975000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394017301362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":31,"alternative-id":["S0304394017301362"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2017.02.030","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adenovirus vector-mediated ex vivo gene transfer of brain-derived neurotrophic factor (BDNF) tohuman umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) promotescrush-injured rat sciatic nerve regeneration","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2017.02.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}