{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:43:32Z","timestamp":1791474212116,"version":"4.3.4"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["CB-2014 240829"],"award-info":[{"award-number":["CB-2014 240829"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["INFR-2016 270549"],"award-info":[{"award-number":["INFR-2016 270549"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020718","name":"Universidad Aut\u00f3noma de Tamaulipas","doi-asserted-by":"publisher","award":["PFI 2016-34"],"award-info":[{"award-number":["PFI 2016-34"]}],"id":[{"id":"10.13039\/501100020718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.neulet.2017.06.042","type":"journal-article","created":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T21:32:04Z","timestamp":1498253524000},"page":"28-34","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Streptozocin-induced type-1 diabetes mellitus results in decreased density of CGRP sensory and TH sympathetic nerve fibers that are positively correlated with bone loss at the mouse femoral neck"],"prefix":"10.1016","volume":"655","author":[{"given":"Iris A.","family":"Enr\u00edquez-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla E.","family":"Galindo-Ordo\u00f1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian E.","family":"Pantoja-Ort\u00edz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arisa\u00ed","family":"Mart\u00ednez-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa I.","family":"Acosta-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enriqueta","family":"Mu\u00f1oz-Islas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan M.","family":"Jim\u00e9nez-Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2017.06.042_bib0005","doi-asserted-by":"crossref","first-page":"820615","DOI":"10.1155\/2014\/820615","article-title":"Osteoporosis fractures, and diabetes","volume":"2014","author":"Jackuliak","year":"2014","journal-title":"Int. J. Endocrinol."},{"issue":"Suppl. 1","key":"10.1016\/j.neulet.2017.06.042_bib0010","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/dmrr.2239","article-title":"Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy","volume":"28","author":"Tesfaye","year":"2012","journal-title":"Diabetes Metab. Rev."},{"issue":"7","key":"10.1016\/j.neulet.2017.06.042_bib0015","first-page":"196","article-title":"Bone mineral density in patients with type 1 and type 2 diabetes","volume":"22","author":"Touminen","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1016\/j.neulet.2017.06.042_bib0020","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1159\/000184273","article-title":"Bone mineral density in children and adolescents with juvenile diabetes: selective measurement of bone mineral density of trabecular and cortical bone using peripheral quantitative computed tomography","volume":"43","author":"Lettgen","year":"1995","journal-title":"Horm. Res."},{"key":"10.1016\/j.neulet.2017.06.042_bib0025","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00198-015-3222-y","article-title":"Trabecular bone score in type 1 diabetes-a cross sectional study","volume":"27","author":"Neumann","year":"2016","journal-title":"Osteoporosis Int."},{"issue":"4","key":"10.1016\/j.neulet.2017.06.042_bib0030","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1530\/EJE-15-0820","article-title":"Mechanisms and evaluation of bone fragility in type 1 diabetes mellitus","volume":"174","author":"Hough","year":"2016","journal-title":"Eur. J. Endocrinol."},{"issue":"5","key":"10.1016\/j.neulet.2017.06.042_bib0035","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/aje\/kwm106","article-title":"Systematic review of type 1 and type 2 diabetes mellitus and risk of fracture","volume":"166","author":"Janghorbani","year":"2007","journal-title":"Am. J. Epidemiol."},{"issue":"Suppl. 6S","key":"10.1016\/j.neulet.2017.06.042_bib0040","first-page":"4","article-title":"Osteoporosis and the burden of osteoporosis-related fractures","volume":"17","author":"Dempster","year":"2011","journal-title":"Am. J. Manag. Care"},{"issue":"12","key":"10.1016\/j.neulet.2017.06.042_bib0045","first-page":"897","article-title":"Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock","volume":"206","author":"Busik","year":"2009","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.neulet.2017.06.042_bib0050","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/jns.12111","article-title":"Effect of diet induced Obesity or type 1 or type 2 diabetes on cornal nerves and peripheral neuropathy in C57B\/6J mice","volume":"20","author":"Yorek","year":"2015","journal-title":"J. Pheripher. Nerve. Syst."},{"key":"10.1016\/j.neulet.2017.06.042_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.diabres.2016.11.006","article-title":"Incidence of complications in young-onset diabetes: comparing type 2 with type 1 (the young diab Study)","volume":"123","author":"Amutha","year":"2017","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"4","key":"10.1016\/j.neulet.2017.06.042_bib0060","first-page":"271","article-title":"Nerve growth factor and diabetic neuropathy","volume":"4","author":"Pittenger","year":"2003","journal-title":"Exp. Diabesity. Res."},{"issue":"1\u20132","key":"10.1016\/j.neulet.2017.06.042_bib0065","first-page":"1","article-title":"Bone and joint neuropathy in rats with type-2 diabetes","volume":"119","author":"Ahmad","year":"2004","journal-title":"Regul. Pept."},{"key":"10.1016\/j.neulet.2017.06.042_bib0070","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.neuroscience.2011.01.039","article-title":"The majority of myelinated and unmyelinated sensory nerve fibers that innervate bone express the tropomyosin receptor kinase A","volume":"178","author":"Casta\u00f1eda-Corral","year":"2011","journal-title":"Neuroscience"},{"issue":"4","key":"10.1016\/j.neulet.2017.06.042_bib0075","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1002\/jcp.22844","article-title":"Amelioration of type 1 diabetes-induced osteoporosis by parathyroid hormone is associated with improved osteoblast survival","volume":"227","author":"Motyl","year":"2012","journal-title":"J.Cell. Physiol."},{"key":"10.1016\/j.neulet.2017.06.042_bib0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0102095","article-title":"Modulation of glucose metabolism by balanced deep-sea water ameliorates hyperglycemia and pancreatic function in streptozotocin-induced diabetic mice","volume":"9","author":"Ha","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neulet.2017.06.042_bib0085","doi-asserted-by":"crossref","first-page":"379287","DOI":"10.1155\/2015\/379287","article-title":"Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice possible role in high-glucose-induced atherogenic process","volume":"2015","author":"Chen","year":"2015","journal-title":"J. Diabetes Res."},{"issue":"5","key":"10.1016\/j.neulet.2017.06.042_bib0090","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1007\/s00223-016-0179-6","article-title":"The central nervous system and bone metabolism: an evolving story","volume":"100","author":"Dimitri","year":"2017","journal-title":"Calcif. Tissue. Int."},{"key":"10.1016\/j.neulet.2017.06.042_bib0095","first-page":"49","article-title":"Is bone a target-tissue for the nervous system? New advances on the understanding of their interactions, Iowa","volume":"20","author":"Garcia-Castellano","year":"2000","journal-title":"Orthop. J."},{"issue":"1","key":"10.1016\/j.neulet.2017.06.042_bib0100","first-page":"76","article-title":"Comparative bone anatomy of commonly used laboratory animals: implication for drug discovery","volume":"61","author":"Bagi","year":"2011","journal-title":"Comp. Med."},{"issue":"12","key":"10.1016\/j.neulet.2017.06.042_bib0105","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.2337\/diacare.28.12.2850","article-title":"Elevated hip fracture risk in type 1 diabetic patients: a population-based cohort study in Sweden","volume":"28","author":"Miao","year":"2005","journal-title":"Diabetes Care"},{"issue":"7","key":"10.1016\/j.neulet.2017.06.042_bib0110","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1002\/art.34385","article-title":"Neuroplasticity of sensory and sympathetic nerve fibers in a mouse model of a painful arthritic joint","volume":"64","author":"Ghilardi","year":"2012","journal-title":"Arthritis. Rheum."},{"issue":"4","key":"10.1016\/j.neulet.2017.06.042_bib0115","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.neuroscience.2009.05.065","article-title":"Capsaicin-sensitive sensory nerve fibers contribute to the generation and maintenance of skeletal fracture pain","volume":"162","author":"Jim\u00e9nez-Andrade","year":"2009","journal-title":"Neuroscience"},{"issue":"9","key":"10.1016\/j.neulet.2017.06.042_bib0120","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1359\/jbmr.090316","article-title":"Type 1 diabetes in young rats leads to progressive trabecular bone loss, cessation of cortical bone growth, and diminished whole bone strength and fatigue life","volume":"24","author":"Silva","year":"2009","journal-title":"J. Bone Miner. Res."},{"issue":"1","key":"10.1016\/j.neulet.2017.06.042_bib0125","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1210\/endo-116-1-296","article-title":"Characterization of the effect of insulin on collagen synthesis in fetal rat bone","volume":"1616","author":"Kream","year":"1985","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.neulet.2017.06.042_bib0130","first-page":"1194","article-title":"Influence of age, sex, and insulin on osteoblast functions: osteoblast dysfunction in diabetes mellitus","volume":"80","author":"Bouillon","year":"1995","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.neulet.2017.06.042_bib0135","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF03343726","article-title":"Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiologic","volume":"23","author":"Kemink","year":"2000","journal-title":"J. Endocrinol. Invest."},{"issue":"2","key":"10.1016\/j.neulet.2017.06.042_bib0140","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/med.10024","article-title":"Abnormal angiogenesis in diabetes mellitus","volume":"23","author":"Martin","year":"2003","journal-title":"Med. Res. Rev."},{"issue":"1","key":"10.1016\/j.neulet.2017.06.042_bib0145","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0022-3565(24)37002-8","article-title":"Insulin-like growth factor (IGF) gene expression is reduced in neural tissues and liver from rats with non-insulin-dependent diabetes mellitus, and IGF treatment ameliorates diabetic neuropathy","volume":"283","author":"Zhuang","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"3","key":"10.1016\/j.neulet.2017.06.042_bib0150","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1093\/jnen\/62.3.260","article-title":"Insulin deficiency rather than hyperglycemia accounts for impaired neurotrophic responses and nerve fibers regeneration in type 1 diabetic neuropathy","volume":"62","author":"Pierson","year":"2003","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"5","key":"10.1016\/j.neulet.2017.06.042_bib0155","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/S0002-9440(10)65480-6","article-title":"Insuline-like growth factor 1 reverses experimental diabetic autonomic neuropathy","volume":"155","author":"Schmidt","year":"1999","journal-title":"Am. J. Pathol."},{"issue":"1","key":"10.1016\/j.neulet.2017.06.042_bib0160","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1006\/exnr.1998.6856","article-title":"Nerve growth factor (NGF) and diabetic neuropathy in the rat: morphological investigations of the sural nerve, dorsal root ganglion, and spinal cord","volume":"153","author":"Unger","year":"1998","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.06.042_bib0165","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/j.1749-6632.1963.tb53782.x","article-title":"Pattern of distribution of calcitonin gene-related peptide in the dorsa root ganglion of animals models of diabetes mellitus","volume":"1084","author":"Adeghate","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"2","key":"10.1016\/j.neulet.2017.06.042_bib0170","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.expneurol.2008.07.001","article-title":"Depletion of peptidergic innervation in the gastric mucosa of streptozotocin-induced diabetic rats","volume":"213","author":"Lin","year":"2008","journal-title":"Exp. Neurol."},{"issue":"2","key":"10.1016\/j.neulet.2017.06.042_bib0175","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1359\/JBMR.041108","article-title":"Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity","volume":"20","author":"Offley","year":"2005","journal-title":"J. Bone Miner. Res."},{"issue":"5","key":"10.1016\/j.neulet.2017.06.042_bib0180","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.bone.2009.11.029","article-title":"Calcitonin-gene-related peptide stimulates stromal cell osteogenic differentiation, and inhibits RANKL induced NF-kappaB activation, osteoclastogenesis and bone resorption","volume":"46","author":"Wang","year":"2010","journal-title":"Bone"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394017305335?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394017305335?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T20:20:21Z","timestamp":1759609221000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394017305335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":36,"alternative-id":["S0304394017305335"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2017.06.042","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Streptozocin-induced type-1 diabetes mellitus results in decreased density of CGRP sensory and TH sympathetic nerve fibers that are positively correlated with bone loss at the mouse femoral neck","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2017.06.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}