{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T13:33:42Z","timestamp":1793885622718,"version":"4.8.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100008722","name":"Universitat de Girona","doi-asserted-by":"publisher","award":["MPCUdG2016\/087"],"award-info":[{"award-number":["MPCUdG2016\/087"]}],"id":[{"id":"10.13039\/100008722","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008722","name":"Universitat de Girona","doi-asserted-by":"publisher","award":["Sing12\/17"],"award-info":[{"award-number":["Sing12\/17"]}],"id":[{"id":"10.13039\/100008722","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.neulet.2017.11.007","type":"journal-article","created":{"date-parts":[[2017,11,7]],"date-time":"2017-11-07T23:07:15Z","timestamp":1510096035000},"page":"98-106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Graded photochemical spinal cord injury results in chronic hyperalgesia and depression-like behaviour but no anxiety exacerbation in female BALB\/c mice"],"prefix":"10.1016","volume":"664","author":[{"given":"Pere","family":"Boadas-Vaello","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judit","family":"Homs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Portero-Tresserra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beltr\u00e1n","family":"\u00c1lvarez-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meritxell","family":"Deulofeu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Verd\u00fa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2017.11.007_bib0005","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1046\/j.1351-5101.2003.00725.x","article-title":"Spinal cord injury pain-mechanisms and treatment","volume":"11","author":"Finnerup","year":"2004","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0010","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/sj.sc.3101641","article-title":"Neuropathic pain after traumatic spinal cord injury-relations to gender spinal level, completeness, and age at the time of injury","volume":"42","author":"Werhagen","year":"2004","journal-title":"Spinal Cord"},{"key":"10.1016\/j.neulet.2017.11.007_bib0015","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.pain.2012.12.007","article-title":"Pain in patients with spinal cord injury","volume":"154","author":"Finnerup","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.neulet.2017.11.007_bib0020","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1046\/j.0007-1331.2001.00727.x","article-title":"Chronic pain, chronic stress and depression: coincidence or consequence?","volume":"13","author":"Blackburn-Munro","year":"2001","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0025","first-page":"504691","article-title":"Neuroplasticity underlying the comorbidity of pain and depression","author":"Doan","year":"2015","journal-title":"Neural. Plast."},{"key":"10.1016\/j.neulet.2017.11.007_bib0030","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/ACO.0000000000000116","article-title":"The anxiodepressive comorbidity in chronic pain","volume":"27","author":"Yalcin","year":"2014","journal-title":"Curr. Opin. Anaesthesiol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0035","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.jpain.2008.12.007","article-title":"Comorbid chronic pain and depression: who is at risk?","volume":"10","author":"Miller","year":"2009","journal-title":"J. Pain"},{"key":"10.1016\/j.neulet.2017.11.007_bib0040","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s11920-013-0421-0","article-title":"Pain and depression: an integrative review of neurobiological and psychological factors","volume":"15","author":"Goesling","year":"2013","journal-title":"Curr. Psychiatry Rep."},{"key":"10.1016\/j.neulet.2017.11.007_bib0045","first-page":"1","article-title":"Safety and efficacy of various combinations of injectable anesthetics in BALB\/c mice","volume":"47","author":"Buitrago","year":"2008","journal-title":"J. Am. Assoc. Lab. Anim. Sci."},{"key":"10.1016\/j.neulet.2017.11.007_bib0050","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1089\/089771503765355559","article-title":"Morphological characterization of photochemical graded spinal cord injury in the rat","volume":"20","author":"Verd\u00fa","year":"2003","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2017.11.007_bib0055","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0301-0082(98)00049-5","article-title":"Spinal cord injury in the rat","volume":"56","author":"Taoka","year":"1998","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0060","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1097\/00001756-200108080-00005","article-title":"Effects of ensheathing cells transplanted into photochemically damaged spinal cord","volume":"12","author":"Verd\u00fa","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.neulet.2017.11.007_bib0065","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1089\/08977150252806965","article-title":"A mouse model of acute ischemic spinal cord injury","volume":"19","author":"Gaviria","year":"2002","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2017.11.007_bib0070","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3340\/jkns.2009.46.5.479","article-title":"A mouse model of photochemically induced spinal cord injury","volume":"46","author":"Piao","year":"2009","journal-title":"J. Korean Neurosurg. Soc."},{"key":"10.1016\/j.neulet.2017.11.007_bib0075","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1474-4422(14)70251-0","article-title":"Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis","volume":"14","author":"Finnerup","year":"2015","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0080","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ctim.2015.12.021","article-title":"Combined approaches for the relief of spinal cord injury-induced neuropathic pain","volume":"25","author":"Gwak","year":"2016","journal-title":"Complement Ther. Med."},{"key":"10.1016\/j.neulet.2017.11.007_bib0085","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.bbr.2006.07.030","article-title":"Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains","volume":"176","author":"Moy","year":"2007","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neulet.2017.11.007_bib0090","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3389\/fnbeh.2015.00110","article-title":"Strain dependent effects of conditioned fear in adult C57Bl\/6 and Balb\/C mice following postnatal exposure to chlorpyrifos: relation to expression of brain acetylcholinesterase mRNA","volume":"9","author":"Oriel","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.neulet.2017.11.007_bib0095","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(88)90026-7","article-title":"A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia","volume":"32","author":"Hargreaves","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.neulet.2017.11.007_bib0100","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/ejp.722","article-title":"Epigallocatechin-3-gallate treatment reduces thermal hyperalgesia after spinal cord injury by down-regulating RhoA expression in mice","volume":"20","author":"\u00c1lvarez-P\u00e9rez","year":"2016","journal-title":"Eur. J. Pain"},{"key":"10.1016\/j.neulet.2017.11.007_bib0105","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1089\/neu.2006.23.635","article-title":"Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains","volume":"23","author":"Basso","year":"2006","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2017.11.007_bib0110","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0031-9384(90)90258-6","article-title":"Gait topography in rat locomotion","volume":"48","author":"Parker","year":"1990","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neulet.2017.11.007_bib0115","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/NEN.0000000000000079","article-title":"Chronic proximal axonopathy in rats is associated with long-standing neurofilament depletion in neuromuscular junctions and behavioral deficits","volume":"73","author":"Soler-Mart\u00edn","year":"2014","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0120","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1101\/lm.030064.112","article-title":"Age-related cognitive impairments in mice with a conditional ablation of the neural cell adhesion molecule","volume":"20","author":"Bisaz","year":"2013","journal-title":"Learn. Mem."},{"key":"10.1016\/j.neulet.2017.11.007_bib0125","first-page":"327","article-title":"Behavioral despair in mice: a primary screening test for antidepressants","volume":"229","author":"Porsolt","year":"1977","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"key":"10.1016\/j.neulet.2017.11.007_bib0130","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ejphar.2014.10.063","article-title":"Rodent models of treatment-resistant depression","volume":"753","author":"Caldarone","year":"2015","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0135","doi-asserted-by":"crossref","first-page":"10989","DOI":"10.1523\/JNEUROSCI.5110-13.2014","article-title":"Spinal cord injury causes brain inflammation associated with cognitive and affective changes: role of cell cycle pathways","volume":"34","author":"Wu","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2017.11.007_bib0140","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/ilar.48.4.385","article-title":"Rat models of traumatic spinal cord injury to assess motor recovery","volume":"48","author":"Onifer","year":"2007","journal-title":"ILAR J."},{"key":"10.1016\/j.neulet.2017.11.007_bib0145","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.expneurol.2011.10.010","article-title":"Spatial and temporal activation of spinal glial cells: role of gliopathy in central neuropathic pain following spinal cord injury in rats","volume":"234","author":"Gwak","year":"2012","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0150","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1006\/exnr.1997.6608","article-title":"Spinal cord injury and anti-NGF treatment results in changes in CGRP density and distribution in the dorsal horn in the rat","volume":"147","author":"Christensen","year":"1997","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0155","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.expneurol.2003.07.002","article-title":"Direct evidence of primary afferent sprouting in distant segments following spinal cord injury in the rat: colocalization of GAP-43 and CGRP","volume":"184","author":"Ondarza","year":"2003","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0160","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/j.pain.0000000000000422","article-title":"Early-onset treadmill training reduces mechanical allodynia and modulates calcitonin gene-related peptide fiber density in lamina III\/IV in a mouse model of spinal cord contusion injury","volume":"157","author":"Nees","year":"2016","journal-title":"Pain"},{"key":"10.1016\/j.neulet.2017.11.007_bib0165","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.bbi.2015.08.009","article-title":"Inflammation is increased with anxiety- and depression-like signs in a rat model of spinal cord injury","volume":"51","author":"Maldonado-Bouchard","year":"2016","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neulet.2017.11.007_bib0170","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.bbr.2006.06.025","article-title":"BALB\/c mice: low sociability and other phenotypes that may be relevant to autism","volume":"176","author":"Brodkin","year":"2007","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neulet.2017.11.007_bib0175","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0166-4328(02)00228-0","article-title":"Home cage activity and behavioral performance in inbred and hybrid mice","volume":"136","author":"Tan","year":"2002","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neulet.2017.11.007_bib0180","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0091-3057(00)00419-6","article-title":"Differences in anxiety-related behavior and response to diazepam in BALB\/cByJ and C57BL\/6J strains of mice","volume":"67","author":"Lepicard","year":"2000","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neulet.2017.11.007_bib0185","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/BF00442824","article-title":"Genetic differences in a tail suspension test for evaluating antidepressant activity","volume":"9","author":"Trullas","year":"1989","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neulet.2017.11.007_bib0190","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ejphar.2008.07.005","article-title":"Mouse strain differences in immobility and sensitivity to fluvoxamine and desipramine in the forced swimming test: analysis of serotonin and noradrenaline transporter binding","volume":"592","author":"Sugimoto","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0195","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s002130050038","article-title":"Differences in anxiety-related behaviours and sensitivity to diazepam in inbred and outbred strains of mice","volume":"148","author":"Griebel","year":"2000","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neulet.2017.11.007_bib0200","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1037\/1064-1297.9.3.277","article-title":"Haloperiodol-induced microcatalepsy differs in CD-1 BALB\/c, and C57BL\/6 mice","volume":"9","author":"Fowler","year":"2001","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0205","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.neulet.2010.06.035","article-title":"Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl\/6 and BALB\/c congenic mice","volume":"481","author":"Siesser","year":"2010","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2017.11.007_bib0210","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.psyneuen.2005.06.005","article-title":"MAO-A knockout attenuates adrenocortical response to various kinds of stress","volume":"31","author":"Popova","year":"2006","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neulet.2017.11.007_bib0215","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.pain.2011.11.001","article-title":"Impact of pain on the course of depressive and anxiety disorders","volume":"153","author":"Gerrits","year":"2012","journal-title":"Pain"},{"key":"10.1016\/j.neulet.2017.11.007_bib0220","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.tins.2016.01.006","article-title":"Neural mechanisms underlying anxiety-chronic pain interactions","volume":"39","author":"Zhuo","year":"2016","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neulet.2017.11.007_bib0225","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.expneurol.2007.04.014","article-title":"Pain behaviors after spinal cord contusion injury in two commonly used mouse strains","volume":"206","author":"Ker","year":"2007","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2017.11.007_bib0230","doi-asserted-by":"crossref","first-page":"16342","DOI":"10.1073\/pnas.1007583107","article-title":"Social interaction modulates autonomic inflammatory, and depressive-like responses to cardiac arrest and cardiopulmonary resuscitation","volume":"107","author":"Norman","year":"2010","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.neulet.2017.11.007_bib0235","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.pbb.2014.06.018","article-title":"Tramadol reduces anxiety-related and depression-associated behaviors presumably induced by pain in the chronic constriction injury model of neuropathic pain in rats","volume":"124","author":"Caspani","year":"2014","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neulet.2017.11.007_bib0240","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/sc.2012.51","article-title":"Effects of chronic pain on quality of life and depression in patients with spinal cord injury","volume":"51","author":"Atao\u011flu","year":"2013","journal-title":"Spinal Cord"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394017309059?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394017309059?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T13:11:56Z","timestamp":1793884316000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394017309059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":48,"alternative-id":["S0304394017309059"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2017.11.007","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Graded photochemical spinal cord injury results in chronic hyperalgesia and depression-like behaviour but no anxiety exacerbation in female BALB\/c mice","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2017.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}