{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:11:34Z","timestamp":1780359094441,"version":"3.54.1"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WA1441\/18-2"],"award-info":[{"award-number":["WA1441\/18-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.neulet.2018.08.028","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T03:09:37Z","timestamp":1534993777000},"page":"74-79","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Neprilysin degrades murine Amyloid-\u03b2 (A\u03b2) more efficiently than human A\u03b2: Further implication for species-specific amyloid accumulation"],"prefix":"10.1016","volume":"686","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9965-6648","authenticated-orcid":false,"given":"Matthias","family":"Becker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maura","family":"Naughton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry","family":"Boland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolf-Eberhard","family":"Siems","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6725-4473","authenticated-orcid":false,"given":"Thomas","family":"Walther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2018.08.028_bib0005","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1161\/01.CIR.97.23.2323","article-title":"Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo","volume":"97","author":"Ferro","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.neulet.2018.08.028_bib0010","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/nm0198-050","article-title":"Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression","volume":"4","author":"Papandreou","year":"1998","journal-title":"Nat. Med."},{"key":"10.1016\/j.neulet.2018.08.028_bib0015","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1126\/science.1059946","article-title":"Metabolic regulation of brain Abeta by neprilysin","volume":"292","author":"Iwata","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.neulet.2018.08.028_bib0020","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1097\/NEN.0b013e3182345e46","article-title":"Abeta-degrading enzymes: potential for treatment of Alzheimer disease","volume":"70","author":"Miners","year":"2011","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neulet.2018.08.028_bib0025","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s00702-002-0807-3","article-title":"Possible increased risk for Alzheimer\u2019s disease associated with neprilysin gene","volume":"110","author":"Clarimon","year":"2003","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.neulet.2018.08.028_bib0030","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1093\/oxfordjournals.jbchem.a003040","article-title":"Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons","volume":"130","author":"Hama","year":"2001","journal-title":"J. Biochem."},{"key":"10.1016\/j.neulet.2018.08.028_bib0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0004590","article-title":"Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase","volume":"4","author":"Walther","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.neulet.2018.08.028_bib0040","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1523\/JNEUROSCI.23-06-01992.2003","article-title":"Neprilysin gene transfer reduces human amyloid pathology in transgenic mice","volume":"23","author":"Marr","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2018.08.028_bib0045","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0169-328X(91)90088-F","article-title":"Conservation of the sequence of the Alzheimer\u2019s disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis","volume":"10","author":"Johnstone","year":"1991","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neulet.2018.08.028_bib0050","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1097\/00002093-200207000-00011","article-title":"Abeta deposition does not cause the aggregation of endogenous tau in transgenic mice","volume":"16","author":"Xu","year":"2002","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"10.1016\/j.neulet.2018.08.028_bib0055","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/0196-9781(95)00021-B","article-title":"Neutral endopeptidase can hydrolyze beta-amyloid(1-40) but shows no effect on beta-amyloid precursor protein metabolism","volume":"16","author":"Howell","year":"1995","journal-title":"Peptides"},{"key":"10.1016\/j.neulet.2018.08.028_bib0060","doi-asserted-by":"crossref","first-page":"14365","DOI":"10.1016\/S0021-9258(17)42607-X","article-title":"Enkephalinase from rat kidney. Purification, characterization, and study of substrate specificity","volume":"259","author":"Malfroy","year":"1984","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neulet.2018.08.028_bib0065","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.peptides.2003.12.010","article-title":"Angiotensin converting enzyme (ACE) and neprilysin hydrolyze neuropeptides: a brief history, the beginning and follow-ups to early studies","volume":"25","author":"Skidgel","year":"2004","journal-title":"Peptides"},{"key":"10.1016\/j.neulet.2018.08.028_bib0070","doi-asserted-by":"crossref","first-page":"5457","DOI":"10.1021\/bi002005e","article-title":"Study of the conformational transition of A beta(1-42) using D-amino acid replacement analogues","volume":"40","author":"Janek","year":"2001","journal-title":"Biochemistry"},{"key":"10.1016\/j.neulet.2018.08.028_bib0075","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3109\/13506120009146831","article-title":"An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments","volume":"7","author":"Fezoui","year":"2000","journal-title":"Amyloid"},{"key":"10.1016\/j.neulet.2018.08.028_bib0080","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1046\/j.1439-0272.2003.00536.x","article-title":"Effects of kinins on mammalian spermatozoa and the impact of peptidolytic enzymes","volume":"35","author":"Siems","year":"2003","journal-title":"Andrologia"},{"key":"10.1016\/j.neulet.2018.08.028_bib0085","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1161\/HYPERTENSIONAHA.116.07572","article-title":"G-protein\u2013coupled receptor MrgD is a receptor for angiotensin-(1\u20137) involving adenylyl cyclase, cAMP, and phosphokinase a","volume":"68","author":"Tetzner","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.neulet.2018.08.028_bib0090","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1515\/BC.2004.036","article-title":"Biochemical analysis of neutral endopeptidase activity reveals independent catabolism of atrial and brain natriuretic peptide","volume":"385","author":"Walther","year":"2004","journal-title":"Biol. Chem."},{"key":"10.1016\/j.neulet.2018.08.028_bib0095","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0896-6273(94)90458-8","article-title":"Visualization of A\u03b242(43) and A\u03b240 in senile plaques with end-specific A\u03b2 monoclonals: evidence that an initially deposited species is A\u03b242(43)","volume":"13","author":"Iwatsubo","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/j.neulet.2018.08.028_bib0100","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1006\/abbi.1993.1112","article-title":"Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer\u2019s disease","volume":"301","author":"Miller","year":"1993","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.neulet.2018.08.028_bib0105","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1111\/j.1471-4159.2006.04426.x","article-title":"A beta oligomers \u2013 a decade of discovery","volume":"101","author":"Walsh","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neulet.2018.08.028_bib0110","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.ejphar.2008.03.058","article-title":"Catabolic attacks of membrane-bound angiotensin-converting enzyme on the N-terminal part of species-specific amyloid-beta peptides","volume":"588","author":"Sun","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neulet.2018.08.028_bib0115","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1046\/j.1432-1327.2001.02248.x","article-title":"Oxidative and hydrolytic properties of \u03b2\u2010amyloid","volume":"268","author":"Brzyska","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.neulet.2018.08.028_bib0120","doi-asserted-by":"crossref","first-page":"40302","DOI":"10.1074\/jbc.M206428200","article-title":"Metalloenzyme-like activity of Alzheimer\u2019s disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2)","volume":"277","author":"Opazo","year":"2002","journal-title":"J. Biol. Chem."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394018305743?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394018305743?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T01:24:05Z","timestamp":1661822645000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394018305743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":24,"alternative-id":["S0304394018305743"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2018.08.028","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neprilysin degrades murine Amyloid-\u03b2 (A\u03b2) more efficiently than human A\u03b2: Further implication for species-specific amyloid accumulation","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2018.08.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}