{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:37:26Z","timestamp":1790861846247,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Science Foundation for Young Scientists of China","award":["81502053"],"award-info":[{"award-number":["81502053"]}]},{"name":"Nantong science and technology project","award":["MS22016008"],"award-info":[{"award-number":["MS22016008"]}]},{"name":"Nantong science and technology project for Young Scientists","award":["WQ2016085"],"award-info":[{"award-number":["WQ2016085"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.neulet.2018.11.021","type":"journal-article","created":{"date-parts":[[2018,11,15]],"date-time":"2018-11-15T18:01:55Z","timestamp":1542304915000},"page":"20-28","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Chemokine CXCL10\/CXCR3 signaling contributes to neuropathic pain in spinal cord and dorsal root ganglia after chronic constriction injury in rats"],"prefix":"10.1016","volume":"694","author":[{"given":"Yonglin","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dekun","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingbing","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunxing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongxiang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongling","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2018.11.021_bib0005","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.aat.2013.08.006","article-title":"The immune aspect in neuropathic pain: role of chemokines","volume":"51","author":"Liou","year":"2013","journal-title":"Acta Anaesthesiol. Taiwan."},{"key":"10.1016\/j.neulet.2018.11.021_bib0010","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1016\/S0140-6736(99)01307-0","article-title":"Neuropathic pain: aetiology, symptoms, mechanisms, and management","volume":"353","author":"Woolf","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.neulet.2018.11.021_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-2999(01)01302-4","article-title":"The clinical picture of neuropathic pain","volume":"429","author":"Jensen","year":"2001","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neulet.2018.11.021_bib0020","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/306686a0","article-title":"Evidence for a central component of post-injury pain hypersensitivity","volume":"306","author":"Woolf","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2018.11.021_bib0025","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/0028-3908(87)90275-9","article-title":"Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation","volume":"26","author":"Dickenson","year":"1987","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neulet.2018.11.021_bib0030","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.pharmthera.2010.01.002","article-title":"Chemokines, neuronal-glial interactions, and central processing of neuropathic pain","volume":"126","author":"Gao","year":"2010","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.neulet.2018.11.021_bib0035","first-page":"1","article-title":"Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain","volume":"521","author":"Watkins","year":"2003","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.neulet.2018.11.021_bib0040","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1097\/00007632-200005150-00003","article-title":"Spinal glial activation and cytokine expression after lumbar root injury in the rat","volume":"25","author":"Hashizume","year":"2000","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.neulet.2018.11.021_bib0045","doi-asserted-by":"crossref","DOI":"10.1007\/s00018-017-2513-1","article-title":"Chemokines in neuron-glial cell interaction and pathogenesis of neuropathic pain","author":"Zhang","year":"2017","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.neulet.2018.11.021_bib0050","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s12264-017-0128-z","article-title":"Chemokine receptor CXCR3 in the spinal cord contributes to chronic itch in mice","volume":"34","author":"Jing","year":"2018","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.neulet.2018.11.021_bib0055","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1128\/JVI.01816-10","article-title":"Upregulation of CXCL10 in human dorsal root ganglia during experimental and natural varicella-zoster virus infection","volume":"85","author":"Steain","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.neulet.2018.11.021_bib0060","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1007\/s10753-017-0520-x","article-title":"Chemokine CXCL13 activates p38 MAPK in the trigeminal ganglion after infraorbital nerve injury","volume":"40","author":"Zhang","year":"2017","journal-title":"Inflammation"},{"key":"10.1016\/j.neulet.2018.11.021_bib0065","doi-asserted-by":"crossref","first-page":"4005","DOI":"10.1038\/s41598-017-04198-3","article-title":"Chemokine receptor CXCR4 regulates CaMKII\/CREB pathway in spinal neurons that underlies cancer-induced bone pain","volume":"7","author":"Hu","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neulet.2018.11.021_bib0070","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/s12974-016-0652-1","article-title":"Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5\/ERK pathway in the trigeminal ganglion of mice","volume":"13","author":"Zhang","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.neulet.2018.11.021_bib0075","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1097\/j.pain.0000000000000208","article-title":"CXCR3 chemokine receptor signaling mediates itch in experimental allergic contact dermatitis","volume":"156","author":"Qu","year":"2015","journal-title":"Pain"},{"key":"10.1016\/j.neulet.2018.11.021_bib0080","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.autrev.2008.12.002","article-title":"CXCL10 and autoimmune diseases","volume":"8","author":"Lee","year":"2009","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.neulet.2018.11.021_bib0085","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.expneurol.2014.09.019","article-title":"Activation of spinal chemokine receptor CXCR3 mediates bone cancer pain through an Akt-ERK crosstalk pathway in rats","volume":"263","author":"Guan","year":"2015","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neulet.2018.11.021_bib0090","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-3959(83)90201-4","article-title":"Ethical guidelines for investigations of experimental pain in conscious animals","volume":"16","author":"Zimmermann","year":"1983","journal-title":"Pain"},{"key":"10.1016\/j.neulet.2018.11.021_bib0095","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of tactile allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.neulet.2018.11.021_bib0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0005709","article-title":"HIV-1 Tat co-operates with IFN-gamma and TNF-alpha to increase CXCL10 in human astrocytes","volume":"4","author":"Williams","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.neulet.2018.11.021_bib0105","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.pediatrneurol.2013.07.019","article-title":"A role for the CXCR3\/CXCL10 axis in Rasmussen encephalitis","volume":"49","author":"Mirones","year":"2013","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.neulet.2018.11.021_bib0110","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/s13075-017-1353-6","article-title":"Pathogenic roles of CXCL10 signaling through CXCR3 and TLR4 in macrophages and T cells: relevance for arthritis","volume":"19","author":"Lee","year":"2017","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.neulet.2018.11.021_bib0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.neuro.051508.135531","article-title":"Neuropathic pain: a maladaptive response of the nervous system to damage","volume":"32","author":"Costigan","year":"2009","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.neulet.2018.11.021_bib0120","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1152\/jn.00187.2017","article-title":"Cl- channel is required for CXCL10-induced neuronal activation and itch response in a murine model of allergic contact dermatitis","volume":"118","author":"Qu","year":"2017","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neulet.2018.11.021_bib0125","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1523\/JNEUROSCI.2262-16.2016","article-title":"Promoted interaction of C\/EBPalpha with demethylated Cxcr3 gene promoter contributes to neuropathic pain in mice","volume":"37","author":"Jiang","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2018.11.021_bib0130","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.neures.2010.01.006","article-title":"NMDA and AMPA receptors contribute to the maintenance of substance P-induced thermal hyperalgesia","volume":"67","author":"Nakayama","year":"2010","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.neulet.2018.11.021_bib0135","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1016\/j.molimm.2010.05.005","article-title":"Evidence for PI3K-dependent CXCR3 agonist-induced degranulation of human cord blood-derived mast cells","volume":"47","author":"Willox","year":"2010","journal-title":"Mol. Immunol."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394018308085?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394018308085?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T20:10:21Z","timestamp":1560024621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394018308085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":27,"alternative-id":["S0304394018308085"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2018.11.021","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chemokine CXCL10\/CXCR3 signaling contributes to neuropathic pain in spinal cord and dorsal root ganglia after chronic constriction injury in rats","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2018.11.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}