{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T09:04:34Z","timestamp":1782551074673,"version":"3.54.5"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.neulet.2019.134305","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T11:22:22Z","timestamp":1559128942000},"page":"134305","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Involvement of monocarboxylate transporters in the cross-tolerance between epilepsy and cerebral infarction: A promising choice towards new treatments"],"prefix":"10.1016","volume":"707","author":[{"given":"Chen","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyi","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2019.134305_bib0005","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00004311-196402000-00008","article-title":"Alterations in lysosomes (intracellular enzymes) during shock; effects of preconditioning (tolerance) and protective drugs","volume":"2","author":"Janoff","year":"1964","journal-title":"Int. Anesthesiol. Clin."},{"issue":"1","key":"10.1016\/j.neulet.2019.134305_bib0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0006-8993(92)91380-W","article-title":"Protection of rat hippocampus against ischemic neuronal damage by pretreatment with sublethal ischemia","volume":"586","author":"Liu","year":"1992","journal-title":"Brain Res."},{"issue":"2","key":"10.1016\/j.neulet.2019.134305_bib0015","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.neuroscience.2007.09.020","article-title":"Microarray profile of seizure damage-refractory hippocampal CA3 in a mouse model of epileptic preconditioning","volume":"150","author":"Hatazaki","year":"2007","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.neulet.2019.134305_bib0020","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.neuropharm.2008.02.017","article-title":"Endogenous neuroprotection: mitochondria as gateways to cerebral preconditioning?","volume":"55","author":"Dirnagl","year":"2008","journal-title":"Neuropharmacology"},{"issue":"5","key":"10.1016\/j.neulet.2019.134305_bib0025","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/S0166-2236(03)00071-7","article-title":"Ischemic tolerance and endogenous neuroprotection","volume":"26","author":"Dirnagl","year":"2003","journal-title":"Trends Neurosci."},{"issue":"4-5","key":"10.1016\/j.neulet.2019.134305_bib0030","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0197-0186(03)00020-2","article-title":"Lactate as a pivotal element in neuron-glia metabolic cooperation","volume":"43","author":"Pellerin","year":"2003","journal-title":"Neurochem. Int."},{"issue":"2","key":"10.1016\/j.neulet.2019.134305_bib0035","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s12035-013-8619-z","article-title":"Decreased astroglial monocarboxylate transporter 4 expression in temporal lobe epilepsy","volume":"50","author":"Liu","year":"2014","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.neulet.2019.134305_bib0040","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.neulet.2015.03.062","article-title":"Monocarboxylate transporter-dependent mechanism confers resistance to oxygen- and glucose-deprivation injury in astrocyte-\u2013neuron co-cultures","volume":"594","author":"Gao","year":"2015","journal-title":"Neurosci. Lett."},{"issue":"11","key":"10.1016\/j.neulet.2019.134305_bib0045","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1007\/s11064-014-1411-2","article-title":"Intermittent hypoxia preconditioning-induced epileptic tolerance by upregulation of monocarboxylate transporter 4 expression in rat hippocampal astrocytes","volume":"39","author":"Gao","year":"2014","journal-title":"Neurochem. Res."},{"issue":"1","key":"10.1016\/j.neulet.2019.134305_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.2005.03168.x","article-title":"Monocarboxylate transporters in the central nervous system: distribution, regulation and function","volume":"94","author":"Pierre","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neulet.2019.134305_bib0055","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2174\/187152408785699622","article-title":"Glycogen metabolism and brain pathologies","volume":"8","author":"Cloix","year":"2008","journal-title":"Cent. Nerv. Syst. Agents Med. Chem."},{"issue":"4","key":"10.1016\/j.neulet.2019.134305_bib0060","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.3892\/etm.2014.1874","article-title":"Pre-ischemic exercise alleviates oxidative damage following ischemic stroke in rats","volume":"8","author":"Feng","year":"2014","journal-title":"Exp. Ther. Med."},{"issue":"20","key":"10.1016\/j.neulet.2019.134305_bib0065","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1016\/0024-3205(81)90659-7","article-title":"Minireview Kainic acid as a tool for the study of temporal lobe epilepsy","volume":"29","author":"Nadler","year":"1981","journal-title":"Life Sci."},{"issue":"2","key":"10.1016\/j.neulet.2019.134305_bib0070","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/0306-4522(96)00195-9","article-title":"Reduced glucose metabolism enhances the glutamate-evoked release of arachidonic acid from striatal neurons","volume":"74","author":"Williams","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2019.134305_bib0075","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/1423-0127-19-78","article-title":"Rapid compensatory changes in the expression of EAAT-3 and GAT-1 transporters during seizures in cells of the CA1 and dentate gyrus","volume":"19","author":"Medina-Ceja","year":"2012","journal-title":"J. Biomed. Sci."},{"issue":"3","key":"10.1016\/j.neulet.2019.134305_bib0080","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s11064-011-0639-3","article-title":"Intermittent hypobaric hypoxia preconditioning induced brain ischemic tolerance by up-regulating glial glutamate transporter-1 in rats","volume":"37","author":"Gong","year":"2012","journal-title":"Neurochem. Res."},{"issue":"12","key":"10.1016\/j.neulet.2019.134305_bib0085","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1051\/medsci\/200420121109","article-title":"Cerebral tolerance: a promising choice towards new treatments for neurologic diseases","volume":"20","author":"Blondeau","year":"2004","journal-title":"Med. Sci. (Paris)"},{"issue":"Pt 12","key":"10.1016\/j.neulet.2019.134305_bib0090","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1242\/jeb.02208","article-title":"Neuron-glia metabolic coupling and plasticity","volume":"209","author":"Magistretti","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.neulet.2019.134305_bib0095","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.pneurobio.2013.11.005","article-title":"Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance","volume":"114","author":"Stetler","year":"2014","journal-title":"Prog. Neurobiol."},{"issue":"2","key":"10.1016\/j.neulet.2019.134305_bib0100","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/0304-3940(89)90569-7","article-title":"Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex","volume":"103","author":"Rosenberg","year":"1989","journal-title":"Neurosci. Lett."},{"issue":"16","key":"10.1016\/j.neulet.2019.134305_bib0105","doi-asserted-by":"crossref","first-page":"4912","DOI":"10.1046\/j.1432-1327.2000.01597.x","article-title":"Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species","volume":"267","author":"Dringen","year":"2000","journal-title":"Eur. J. Biochem."},{"issue":"1","key":"10.1016\/j.neulet.2019.134305_bib0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0301-0082(00)00067-8","article-title":"Glutamate uptake","volume":"65","author":"Danbolt","year":"2001","journal-title":"Prog. Neurobiol."},{"issue":"3","key":"10.1016\/j.neulet.2019.134305_bib0115","doi-asserted-by":"crossref","first-page":"e00062","DOI":"10.1042\/AN20100029","article-title":"Pre-conditioning induces the precocious differentiation of neonatal astrocytes to enhance their neuroprotective properties","volume":"3","author":"Sen","year":"2011","journal-title":"ASN Neuro"},{"issue":"4","key":"10.1016\/j.neulet.2019.134305_bib0120","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s002210000600","article-title":"A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is colocalized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses","volume":"136","author":"Bergersen","year":"2001","journal-title":"Exp. Brain Res."},{"issue":"1","key":"10.1016\/j.neulet.2019.134305_bib0125","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.nbd.2011.08.001","article-title":"Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy","volume":"45","author":"Lauritzen","year":"2012","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neulet.2019.134305_bib0130","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/nrc3579","article-title":"Disrupting proton dynamics and energy metabolism for cancer therapy","volume":"13","author":"Parks","year":"2013","journal-title":"Nat. Rev. Cancer"},{"issue":"1","key":"10.1016\/j.neulet.2019.134305_bib0135","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1371\/journal.pone.0085449","article-title":"Capturing intracellular pH dynamics by coupling its molecular mechanisms within a fully tractable mathematical model","volume":"9","author":"Bouret","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neulet.2019.134305_bib0140","doi-asserted-by":"crossref","first-page":"13605","DOI":"10.1038\/srep13605","article-title":"Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function","volume":"5","author":"Jamali","year":"2015","journal-title":"Sci. Rep."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394019303787?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394019303787?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T20:26:39Z","timestamp":1759609599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394019303787"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":28,"alternative-id":["S0304394019303787"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2019.134305","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Involvement of monocarboxylate transporters in the cross-tolerance between epilepsy and cerebral infarction: A promising choice towards new treatments","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2019.134305","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"134305"}}