{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:27:09Z","timestamp":1790508429887,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,14]],"date-time":"2020-06-14T00:00:00Z","timestamp":1592092800000},"content-version":"am","delay-in-days":287,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.neulet.2019.134329","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T13:39:14Z","timestamp":1560260354000},"page":"134329","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Anti-repulsive guidance molecule-a antibody treatment and repetitive transcranial magnetic stimulation have synergistic effects on motor recovery after spinal cord injury"],"prefix":"10.1016","volume":"709","author":[{"given":"Toru","family":"Nakanishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4559-7018","authenticated-orcid":false,"given":"Toshihide","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2019.134329_bib0005","first-page":"617","article-title":"Glial inhibition of CNS axon regeneration, Nature reviews","volume":"7","author":"Yiu","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2019.134329_bib0010","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/0896-6273(90)90227-7","article-title":"Biochemical characterization of a putative axonal guidance molecule of the chick visual system","volume":"5","author":"Stahl","year":"1990","journal-title":"Neuron"},{"key":"10.1016\/j.neulet.2019.134329_bib0015","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/S0960-9822(96)00754-3","article-title":"Chromophore-assisted laser inactivation of a repulsive axonal guidance molecule","volume":"6","author":"Muller","year":"1996","journal-title":"Curr. Biol.: CB"},{"key":"10.1016\/j.neulet.2019.134329_bib0020","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1038\/nature01041","article-title":"RGM is a repulsive guidance molecule for retinal axons","volume":"419","author":"Monnier","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2019.134329_bib0025","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/ncb1156","article-title":"Neogenin mediates the action of repulsive guidance molecule","volume":"6","author":"Rajagopalan","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.neulet.2019.134329_bib0030","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1083\/jcb.200508143","article-title":"RGMa inhibition promotes axonal growth and recovery after spinal cord injury","volume":"173","author":"Hata","year":"2006","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neulet.2019.134329_bib0035","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/cercor\/bhx338","article-title":"Treatment with the neutralizing antibody against repulsive guidance molecule-a promotes recovery from impaired manual dexterity in a primate model of spinal cord injury","volume":"29","author":"Nakagawa","year":"2019","journal-title":"Cerebral Cortex (New York, N.Y.: 1991)"},{"key":"10.1016\/j.neulet.2019.134329_bib0040","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1016\/j.clinph.2006.06.712","article-title":"A comprehensive review of the effects of rTMS on motor cortical excitability and inhibition","volume":"117","author":"Fitzgerald","year":"2006","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.neulet.2019.134329_bib0045","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/jnr.10852","article-title":"Repetitive transcranial magnetic stimulation improves open field locomotor recovery after low but not high thoracic spinal cord compression-injury in adult rats","volume":"75","author":"Poirrier","year":"2004","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neulet.2019.134329_bib0050","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/sj.sc.3101613","article-title":"Magnetic brain stimulation can improve clinical outcome in incomplete spinal cord injured patients","volume":"42","author":"Belci","year":"2004","journal-title":"Spinal Cord"},{"key":"10.1016\/j.neulet.2019.134329_bib0055","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1074\/jbc.M110.163493","article-title":"Paired immunoglobulin-like receptor B knockout does not enhance axonal regeneration or locomotor recovery after spinal cord injury","volume":"286","author":"Nakamura","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neulet.2019.134329_bib0060","doi-asserted-by":"crossref","first-page":"14769","DOI":"10.1038\/srep14769","article-title":"Transcranial magnetic stimulation facilitates neurorehabilitation after pediatric traumatic brain injury","volume":"5","author":"Lu","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neulet.2019.134329_bib0065","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/j.ajpath.2011.12.012","article-title":"FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms","volume":"180","author":"Norimatsu","year":"2012","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.neulet.2019.134329_bib0070","doi-asserted-by":"crossref","first-page":"10429","DOI":"10.1523\/JNEUROSCI.1718-15.2015","article-title":"Gene-silencing screen for mammalian axon regeneration identifies Inpp5f (Sac2) as an endogenous suppressor of repair after spinal cord injury","volume":"35","author":"Zou","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2019.134329_bib0075","doi-asserted-by":"crossref","first-page":"e534","DOI":"10.1038\/cddis.2013.62","article-title":"Bilateral movement training promotes axonal remodeling of the corticospinal tract and recovery of motor function following traumatic brain injury in mice","volume":"4","author":"Nakagawa","year":"2013","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.neulet.2019.134329_bib0080","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0165-0270(02)00012-2","article-title":"Cortical and subcortical lesions impair skilled walking in the ladder rung walking test: a new task to evaluate fore- and hindlimb stepping, placing, and co-ordination","volume":"115","author":"Metz","year":"2002","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.neulet.2019.134329_bib0085","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1089\/neu.2006.23.635","article-title":"Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains","volume":"23","author":"Basso","year":"2006","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2019.134329_bib0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/neu.2008.0543","article-title":"Anatomical and functional outcomes following a precise, graded, dorsal laceration spinal cord injury in C57BL\/6 mice","volume":"26","author":"Hill","year":"2009","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2019.134329_bib0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030461","article-title":"Single collateral reconstructions reveal distinct phases of corticospinal remodeling after spinal cord injury","volume":"7","author":"Lang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neulet.2019.134329_bib0100","first-page":"169","article-title":"Mechanisms of CaMKII action in long-term potentiation, Nature reviews","volume":"13","author":"Lisman","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2019.134329_bib0105","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1126\/science.1253050","article-title":"Neuronal repair. Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke","volume":"344","author":"Wahl","year":"2014","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.neulet.2019.134329_bib0110","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aac5811","article-title":"Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates","volume":"7","author":"Friedli","year":"2015","journal-title":"Sci. Transl. Med."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394019304288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394019304288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T20:26:59Z","timestamp":1759609619000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394019304288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":22,"alternative-id":["S0304394019304288"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2019.134329","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anti-repulsive guidance molecule-a antibody treatment and repetitive transcranial magnetic stimulation have synergistic effects on motor recovery after spinal cord injury","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2019.134329","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"134329"}}