{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T11:39:33Z","timestamp":1778758773102,"version":"3.51.4"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.neulet.2021.135976","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T00:10:23Z","timestamp":1621555823000},"page":"135976","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["A high-fat diet, but not haloperidol or olanzapine administration, increases activated microglial expression in the rat brain"],"prefix":"10.1016","volume":"757","author":[{"given":"Marsha","family":"Maredia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panayotis K.","family":"Thanos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl 2","key":"10.1016\/j.neulet.2021.135976_bib0005","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/jnc.13607","article-title":"Neuroinflammation: the devil is in the details","volume":"139","author":"DiSabato","year":"2016","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0010","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/glia.22357","article-title":"Molecular imaging of microglia\/macrophages in the brain","volume":"61","author":"Venneti","year":"2013","journal-title":"Glia"},{"key":"10.1016\/j.neulet.2021.135976_bib0015","series-title":"Neurological Disorders Affect Millions Globally: WHO Report","author":"Bertolote","year":"2010"},{"issue":"7321","key":"10.1016\/j.neulet.2021.135976_bib0020","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/nature09615","article-title":"The myeloid cells of the central nervous system parenchyma","volume":"468","author":"Ransohoff","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2021.135976_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bcp.2015.11.003","article-title":"Functional polarization of neuroglia: implications in neuroinflammation and neurological disorders","volume":"103","author":"Jha","year":"2016","journal-title":"Biochem. Pharmacol."},{"issue":"6","key":"10.1016\/j.neulet.2021.135976_bib0030","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1038\/nn1472","article-title":"ATP mediates rapid microglial response to local brain injury in vivo","volume":"8","author":"Davalos","year":"2005","journal-title":"Nat. Neurosci."},{"issue":"12","key":"10.1016\/j.neulet.2021.135976_bib0035","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1038\/sj.jcbfm.9600500","article-title":"Imaging brain inflammation with [(11)C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in rats","volume":"27","author":"Rojas","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"6","key":"10.1016\/j.neulet.2021.135976_bib0040","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0924-977X(02)00107-4","article-title":"In vivo imaging of neuroinflammation","volume":"12","author":"Cagnin","year":"2002","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"12","key":"10.1016\/j.neulet.2021.135976_bib0045","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1038\/mp.2016.180","article-title":"In vivo imaging of brain microglial activity in antipsychotic-free and medicated schizophrenia: a [11C](R)-PK11195 positron emission tomography study","volume":"21","author":"Holmes","year":"2016","journal-title":"Mol. Psychiatry"},{"issue":"9","key":"10.1016\/j.neulet.2021.135976_bib0050","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.biopsych.2008.04.025","article-title":"Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study","volume":"64","author":"van Berckel","year":"2008","journal-title":"Biol. Psychiatry"},{"issue":"11","key":"10.1016\/j.neulet.2021.135976_bib0055","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.2967\/jnumed.109.066647","article-title":"Neuroinflammation in schizophrenia-related psychosis: a PET study","volume":"50","author":"Doorduin","year":"2009","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.neulet.2021.135976_bib0060","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.pnpbp.2012.12.013","article-title":"Is there an association between peripheral immune markers and structural\/functional neuroimaging findings?","volume":"48","author":"Frodl","year":"2014","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.neulet.2021.135976_bib0065","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1097\/YCO.0000000000000535","article-title":"Ketogenic diet for schizophrenia: clinical implication","volume":"32","author":"Sarnyai","year":"2019","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.neulet.2021.135976_bib0070","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.mehy.2018.06.022","article-title":"Ketogenic diet for schizophrenia: nutritional approach to antipsychotic treatment","volume":"118","author":"W\u0142odarczyk","year":"2018","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.neulet.2021.135976_bib0075","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.nlm.2018.11.008","article-title":"High fat diet increases cognitive decline and neuroinflammation in a model of orexin loss","volume":"157","author":"Duffy","year":"2019","journal-title":"Neurobiol. Learn. Mem."},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jneuroim.2009.11.010","article-title":"Cognitive impairment following high fat diet consumption is associated with brain inflammation","volume":"219","author":"Pistell","year":"2010","journal-title":"J. Neuroimmunol."},{"issue":"3","key":"10.1016\/j.neulet.2021.135976_bib0085","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00401-016-1595-4","article-title":"High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia","volume":"132","author":"Baufeld","year":"2016","journal-title":"Acta Neuropathol."},{"issue":"11","key":"10.1016\/j.neulet.2021.135976_bib0090","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.3390\/nu11112579","article-title":"Effect of high-fat diets on oxidative stress, cellular inflammatory response and cognitive function","volume":"11","author":"Tan","year":"2019","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.neulet.2021.135976_bib0095","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S1474-4422(17)30084-4","article-title":"Neurological consequences of obesity","volume":"16","author":"O\u2019Brien","year":"2017","journal-title":"Lancet Neurol."},{"issue":"4","key":"10.1016\/j.neulet.2021.135976_bib0100","first-page":"451","article-title":"Comparison of efficacy of haloperidol and olanzapine in the treatment of delirium","volume":"59","author":"Jain","year":"2017","journal-title":"Indian J. Psychiatry"},{"key":"10.1016\/j.neulet.2021.135976_bib0105","article-title":"Number of people with purchase in thousands by therapeutic class, United States 1996-2017","author":"Agency for Healthcare Research and Quality","year":"2016","journal-title":"Med. Expend. Panel Surv."},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0110","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1192\/bjpo.bp.115.002576","article-title":"Long-term antipsychotic treatment in schizophrenia: systematic review and network meta-analysis of randomised controlled trials","volume":"2","author":"Zhao","year":"2016","journal-title":"BJPsych Open"},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0115","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1038\/s41598-018-36930-y","article-title":"Chronic olanzapine administration causes metabolic syndrome through inflammatory cytokines in rodent models of insulin resistance","volume":"9","author":"Li","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neulet.2021.135976_bib0120","series-title":"N.I.o.M.H. Mental Health Medications","author":"(NIMH)","year":"2016"},{"issue":"753","key":"10.1016\/j.neulet.2021.135976_bib0125","article-title":"Constructing the immune signature of schizophrenia for clinical use and research; an integrative review translating descriptives into diagnostics","volume":"9","author":"Kroken","year":"2019","journal-title":"Front. Psychiatry"},{"issue":"9","key":"10.1016\/j.neulet.2021.135976_bib0130","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1007\/s00213-015-3976-0","article-title":"Inflammation and psychotropic drugs: the relationship between C-reactive protein and antipsychotic drug levels","volume":"233","author":"Hefner","year":"2016","journal-title":"Psychopharmacology"},{"issue":"4","key":"10.1016\/j.neulet.2021.135976_bib0135","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1038\/mp.2015.87","article-title":"C-reactive protein is increased in schizophrenia but is not altered by antipsychotics: meta-analysis and implications","volume":"21","author":"Fernandes","year":"2016","journal-title":"Mol. Psychiatry"},{"issue":"9","key":"10.1016\/j.neulet.2021.135976_bib0140","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1093\/ijnp\/pyy062","article-title":"Kinetics of cytokine levels during antipsychotic treatment in schizophrenia: a meta-analysis","volume":"21","author":"Romeo","year":"2018","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.neulet.2021.135976_bib0145","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.pnpbp.2012.10.022","article-title":"The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia","volume":"48","author":"Na","year":"2014","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.neulet.2021.135976_bib0150","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0920-9964(00)00156-0","article-title":"Neuroleptics normalize increased release of interleukin-1\u03b2 and tumor necrosis factor-\u03b1 from monocytes in schizophrenia","volume":"50","author":"Kowalski","year":"2001","journal-title":"Schizophr. Res."},{"issue":"4","key":"10.1016\/j.neulet.2021.135976_bib0155","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1159\/000067807","article-title":"The influence of typical and atypical neuroleptic drugs in the production of interleukin-2 and interferon-gamma in vitro","volume":"46","author":"Rudolf","year":"2002","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.neulet.2021.135976_bib0160","first-page":"329","article-title":"Neuroinflammation in schizophrenia: a critical review and the future","volume":"26","author":"Aricioglu","year":"2016","journal-title":"Klinik Psikofarmakoloji Bulteni-Bull. Clin. Psychopharmacol."},{"issue":"63","key":"10.1016\/j.neulet.2021.135976_bib0165","article-title":"Exposure to prenatal infection and risk of schizophrenia","volume":"2","author":"Brown","year":"2011","journal-title":"Front. Psychiatry"},{"issue":"4","key":"10.1016\/j.neulet.2021.135976_bib0170","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/bph.13364","article-title":"Microglial activation and progressive brain changes in schizophrenia","volume":"173","author":"Laskaris","year":"2016","journal-title":"Br. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.neulet.2021.135976_bib0175","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1054\/mehy.1999.0018","article-title":"Microglia dysfunction in schizophrenia: an integrative theory","volume":"54","author":"Munn","year":"2000","journal-title":"Med. Hypotheses"},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.arcmed.2007.10.001","article-title":"Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer\u2019s disease","volume":"39","author":"Rojo","year":"2008","journal-title":"Arch. Med. Res."},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0185","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/YCO.0b013e32835aa4b4","article-title":"Is bipolar disorder an inflammatory condition? The relevance of microglial activation","volume":"26","author":"Stertz","year":"2013","journal-title":"Curr. Opin. Psychiatry"},{"issue":"Pt B","key":"10.1016\/j.neulet.2021.135976_bib0190","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.pnpbp.2017.06.005","article-title":"Oral haloperidol or olanzapine intake produces distinct and region-specific increase in cannabinoid receptor levels that is prevented by high fat diet","volume":"79","author":"Delis","year":"2017","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.neulet.2021.135976_bib0195","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/j.neuroscience.2007.03.003","article-title":"Oral haloperidol or risperidone treatment in rats: temporal effects on nerve growth factor receptors, cholinergic neurons, and memory performance","volume":"146","author":"Terry","year":"2007","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/j.neulet.2021.135976_bib0200","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1176\/ajp.156.2.286","article-title":"Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia","volume":"156","author":"Kapur","year":"1999","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.neulet.2021.135976_bib0205","doi-asserted-by":"crossref","DOI":"10.1124\/jpet.102.046987","article-title":"Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy","volume":"305","author":"Kapur","year":"2003","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"26","key":"10.1016\/j.neulet.2021.135976_bib0210","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1016\/j.lfs.2005.11.031","article-title":"Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer","volume":"78","author":"Barth","year":"2006","journal-title":"Life Sci."},{"issue":"2","key":"10.1016\/j.neulet.2021.135976_bib0215","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.neuroimage.2010.02.073","article-title":"Transient focal ischemia results in persistent and widespread neuroinflammation and loss of glutamate NMDA receptors","volume":"51","author":"Dhawan","year":"2010","journal-title":"Neuroimage"},{"issue":"7","key":"10.1016\/j.neulet.2021.135976_bib0220","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/syn.20889","article-title":"Regional sensitivity to neuroinflammation: in vivo and in vitro studies","volume":"65","author":"Liraz-Zaltsman","year":"2011","journal-title":"Synapse"},{"key":"10.1016\/j.neulet.2021.135976_bib0225","series-title":"The Rat Brain in Stereotaxic Coordinates: Hard Cover Edition","author":"Paxinos","year":"2006"},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0230","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.neuro.29.051605.113046","article-title":"Visual perception and memory: a new view of medial temporal lobe function in primates and rodents","volume":"30","author":"Murray","year":"2007","journal-title":"Annu. Rev. Neurosci."},{"issue":"509","key":"10.1016\/j.neulet.2021.135976_bib0235","article-title":"High-fat diet induces neuroinflammation and mitochondrial impairment in mice cerebral cortex and synaptic fraction","volume":"13","author":"Cavaliere","year":"2019","journal-title":"Front. Cell. Neurosci."},{"issue":"7","key":"10.1016\/j.neulet.2021.135976_bib0240","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1038\/npp.2015.357","article-title":"High-fat diet induced anxiety and anhedonia: impact on brain homeostasis and inflammation","volume":"41","author":"Dutheil","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0245","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1186\/s12974-016-0666-8","article-title":"High-fat diet feeding differentially affects the development of inflammation in the central nervous system","volume":"13","author":"Guillemot-Legris","year":"2016","journal-title":"J. Neuroinflammation"},{"issue":"2","key":"10.1016\/j.neulet.2021.135976_bib0250","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0959-4388(96)80071-7","article-title":"The anatomy, physiology and functions of the perirhinal cortex","volume":"6","author":"Suzuki","year":"1996","journal-title":"Curr. Opin. Neurobiol."},{"issue":"7721","key":"10.1016\/j.neulet.2021.135976_bib0255","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/s41586-018-0459-6","article-title":"Integrating time from experience in the lateral entorhinal cortex","volume":"561","author":"Tsao","year":"2018","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.neulet.2021.135976_bib0260","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1016\/j.euroneuro.2015.08.004","article-title":"Microglial activation in the rat brain following chronic antipsychotic treatment at clinically relevant doses","volume":"25","author":"Cotel","year":"2015","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"11","key":"10.1016\/j.neulet.2021.135976_bib0265","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1177\/0269881118788830","article-title":"The effects of haloperidol on microglial morphology and translocator protein levels: an in vivo study in rats using an automated cell evaluation pipeline","volume":"32","author":"Bloomfield","year":"2018","journal-title":"J. Psychopharmacol."},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0270","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.encep.2007.07.005","article-title":"[Mortality among chronic schizophrenic patients: a prospective 14-year follow-up study of 150 schizophrenic patients]","volume":"34","author":"Loas","year":"2008","journal-title":"LEncephale"},{"key":"10.1016\/j.neulet.2021.135976_bib0275","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1080\/17522430903501999","article-title":"Antipsychotic medication, mortality and neurodegeneration: the need for more selective use and lower doses","volume":"2","author":"Weinmann","year":"2010","journal-title":"Psychosis"},{"issue":"1","key":"10.1016\/j.neulet.2021.135976_bib0280","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.schres.2008.07.006","article-title":"Antipsychotic effects on estimated 10-year coronary heart disease risk in the CATIE schizophrenia study","volume":"105","author":"Daumit","year":"2008","journal-title":"Schizophr. Res."},{"issue":"5","key":"10.1016\/j.neulet.2021.135976_bib0285","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/cercor\/bhn152","article-title":"Time-lapse mapping of cortical changes in schizophrenia with different treatments","volume":"19","author":"Thompson","year":"2009","journal-title":"Cereb. Cortex"},{"issue":"10","key":"10.1016\/j.neulet.2021.135976_bib0290","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1007\/s11064-006-9162-3","article-title":"Possible mechanisms of neurodegeneration in schizophrenia","volume":"31","author":"P\u00e9rez-Neri","year":"2006","journal-title":"Neurochem. Res."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394021003542?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394021003542?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T20:40:15Z","timestamp":1759610415000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394021003542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":58,"alternative-id":["S0304394021003542"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2021.135976","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A high-fat diet, but not haloperidol or olanzapine administration, increases activated microglial expression in the rat brain","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2021.135976","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"135976"}}