{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T10:39:15Z","timestamp":1766486355091,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.neulet.2022.136940","type":"journal-article","created":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T12:35:41Z","timestamp":1667478941000},"page":"136940","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Alterations in the activation of corticotropin-releasing factor neurons in the paraventricular nucleus following a single or multiple days of sleep restriction"],"prefix":"10.1016","volume":"792","author":[{"given":"Katelyn N.","family":"Buban","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha E.","family":"Saperstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario G.","family":"Oyola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen W.","family":"Rothwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"John Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.neulet.2022.136940_b0005","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.jpsychires.2006.07.008","article-title":"The association of insomnia with anxiety disorders and depression: exploration of the direction of risk","volume":"40","author":"Johnson","year":"2006","journal-title":"J. Psychiatr. Res."},{"issue":"6","key":"10.1016\/j.neulet.2022.136940_b0010","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/s11920-013-0364-5","article-title":"Comorbid sleep disorders in neuropsychiatric disorders across the life cycle","volume":"15","author":"Spiegelhalder","year":"2013","journal-title":"Curr. Psychiatry Rep."},{"issue":"1","key":"10.1016\/j.neulet.2022.136940_b0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/joe.0.1600001","article-title":"The role of corticotropin-releasing factor in depression and anxiety disorders","volume":"160","author":"Arborelius","year":"1999","journal-title":"J. Endocrinol."},{"issue":"5","key":"10.1016\/j.neulet.2022.136940_b0020","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1210\/jc.2004-1056","article-title":"On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm, exemplary sleep disorders","volume":"90","author":"Buckley","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"9188","key":"10.1016\/j.neulet.2022.136940_b0025","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/S0140-6736(99)01376-8","article-title":"Impact of sleep debt on metabolic and endocrine function","volume":"354","author":"Spiegel","year":"1999","journal-title":"The Lancet"},{"issue":"7","key":"10.1016\/j.neulet.2022.136940_b0030","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1046\/j.1365-2826.2002.00812.x","article-title":"Hormonal and behavioural responses of paradoxical sleep-deprived rats to the elevated plus maze","volume":"14","author":"Suchecki","year":"2002","journal-title":"J. Neuroendocrinol."},{"issue":"2\u20133","key":"10.1016\/j.neulet.2022.136940_b0035","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0091-3057(01)00620-7","article-title":"Further definition of the effect of corticosterone on the sleep-wake pattern in the male rat","volume":"70","author":"Vazquez-Palacios","year":"2001","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"2","key":"10.1016\/j.neulet.2022.136940_b0040","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1053\/smrv.2001.0159","article-title":"Sleep and the hypothalamo-pituitary-adrenocortical system","volume":"6","author":"Steiger","year":"2002","journal-title":"Sleep Med. Rev."},{"issue":"1-2","key":"10.1016\/j.neulet.2022.136940_b0045","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0031-9384(00)00285-7","article-title":"Effect of electric foot shocks, immobilization, and corticosterone administration on the sleep-wake pattern in the rat","volume":"71","author":"Vazquez-Palacios","year":"2000","journal-title":"Physiol. Behav."},{"issue":"3","key":"10.1016\/j.neulet.2022.136940_b0050","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/jsr.12269","article-title":"Paradoxical (REM) sleep deprivation in mice using the small-platforms-over-water method: polysomnographic analyses and melanin-concentrating hormone and hypocretin\/orexin neuronal activation before, during and after deprivation","volume":"24","author":"Arthaud","year":"2015","journal-title":"J. Sleep Res."},{"issue":"5","key":"10.1016\/j.neulet.2022.136940_b0055","doi-asserted-by":"crossref","first-page":"e63520","DOI":"10.1371\/journal.pone.0063520","article-title":"Role of Corticosterone on Sleep Homeostasis Induced by REM Sleep Deprivation in Rats","volume":"8","author":"Machado","year":"2013","journal-title":"PLoS ONE"},{"issue":"5","key":"10.1016\/j.neulet.2022.136940_b0060","first-page":"397","article-title":"Sleep Restriction Alters the Hypothalamic-Pituitary-Adrenal Response to","volume":"14","author":"Meerlo","year":"2002","journal-title":"Stress"},{"issue":"2","key":"10.1016\/j.neulet.2022.136940_b0065","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.psyneuen.2005.06.009","article-title":"Effects of sleep deprivation on cardiac autonomic and pituitary-adrenocortical stress reactivity in rats","volume":"31","author":"Sgoifo","year":"2006","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"10.1016\/j.neulet.2022.136940_b0070","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0014-2999(03)01285-8","article-title":"Neuroendocrine pharmacology of stress","volume":"463","author":"Carrasco","year":"2003","journal-title":"Eur. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.neulet.2022.136940_b0075","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.yfrne.2013.11.001","article-title":"Gonadal steroid hormones and the hypothalamo\u2013pituitary\u2013adrenal axis","volume":"35","author":"Handa","year":"2014","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.neulet.2022.136940_b0080","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2019.00676","article-title":"Sleep deprivation alters the pituitary stress transcriptome in male and female mice","author":"Oyola","year":"2019","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.neulet.2022.136940_b0085","doi-asserted-by":"crossref","DOI":"10.1080\/10253890.2019.1710488","article-title":"Sex differences in the hypothalamic-pituitary-adrenal axis response following a single or multiple days of sleep restriction","author":"Buban","year":"2020","journal-title":"Stress"},{"issue":"5","key":"10.1016\/j.neulet.2022.136940_b0090","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1006\/phrs.1997.0155","article-title":"Stress-induced sleep deprivation modifies corticotropin releasing factor (CRF) levels and CRF binding in rat brain and pituitary","volume":"35","author":"Fadda","year":"1997","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.neulet.2022.136940_b0095","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s42000-018-0002-z","article-title":"Sex differences in stress responses: a critical role for corticotropin-releasing factor","volume":"17","author":"Bangasser","year":"2018","journal-title":"Hormones"},{"issue":"3","key":"10.1016\/j.neulet.2022.136940_b0100","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0031-9384(99)00181-X","article-title":"Social stability attenuates the stress in the modified multiple platform method for paradoxical sleep deprivation in the rat","volume":"68","author":"Suchecki","year":"2000","journal-title":"Physiol. Behav."},{"issue":"6","key":"10.1016\/j.neulet.2022.136940_b0105","doi-asserted-by":"crossref","first-page":"23630","DOI":"10.1210\/en.2018-00203","article-title":"Differential responses of the HPA axis to to mild blast traumatic brain injury in male and female mice","volume":"159","author":"Russell","year":"2018","journal-title":"Endocrinology"},{"year":"2019","series-title":"Paxino\u2019s and Franklin\u2019s the Mouse Brain in Stereotaxic Coordinates","author":"Paxinos","key":"10.1016\/j.neulet.2022.136940_b0110"},{"key":"10.1016\/j.neulet.2022.136940_b0115","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0197-0186(98)00023-0","article-title":"c-Fos as a transcription facor: a stressful (re)view from a functional map","volume":"33","author":"Kovacs","year":"1998","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neulet.2022.136940_b0120","first-page":"71","article-title":"Gene regulation system of vasopressin and corticotropin-releasing hormone","volume":"2","author":"Yoshida","year":"2008","journal-title":"Gene Regul. Syst. Biol."},{"issue":"4","key":"10.1016\/j.neulet.2022.136940_b0125","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12079-013-0197-3","article-title":"An integrated map of corticotropin-releasing hormone signaling pathway","volume":"7","author":"Subbannayya","year":"2013","journal-title":"J. Cell Commun. Signaling"},{"issue":"12","key":"10.1016\/j.neulet.2022.136940_b0130","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1016\/j.peptides.2010.08.022","article-title":"mRNA expression of corticotropin-releasing factor and urocortin 1 after restraint and foot shock together with alprazolam administration","volume":"31","author":"Cespedes","year":"2010","journal-title":"Peptides"},{"key":"10.1016\/j.neulet.2022.136940_b0135","doi-asserted-by":"crossref","unstructured":"S. Schuh-Hofer, N. Eichhorn, V. Grinevich, R.D. Treede. (2018). Sleep Deprivation Related Changes of Plasma Oxytocin in Males and Female Contraceptive Users Depend on Sex and Correlate Differentially With Anxiety and Pain Hypersensitivity. Front Behav Neurosci. 2018 Aug 2;12:161. doi: 10.3389\/fnbeh.2018.00161. PMID: 30116181; PMCID: PMC6082934.","DOI":"10.3389\/fnbeh.2018.00161"},{"issue":"2\u20133","key":"10.1016\/j.neulet.2022.136940_b0140","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0167-0115(03)00118-6","article-title":"Intracerebral oxytocin modulates sleep-wake behaviour in male rats","volume":"114","author":"Lancel","year":"2003","journal-title":"Regul. Pept."},{"issue":"2","key":"10.1016\/j.neulet.2022.136940_b0145","doi-asserted-by":"crossref","first-page":"F236","DOI":"10.1152\/ajprenal.00283.2011","article-title":"Sleep deprivation induces excess diuresis and natriuresis in healthy children","volume":"302","author":"Mahler","year":"2012","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.neulet.2022.136940_b0150","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1046\/j.1365-2826.2002.00812.x","article-title":"Hormonal and behavioural responses of paradoxical sleep-deprived rats to the elevated plus maze","volume":"7","author":"Suchecki","year":"2002","journal-title":"J. Neuroendocrinol."},{"issue":"1\u20132","key":"10.1016\/j.neulet.2022.136940_b0155","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0304-3940(02)00024-1","article-title":"Paradoxical sleep deprivation facilitates subsequent corticosterone response to a mild stressor in rats","volume":"320","author":"Suchecki","year":"2002","journal-title":"Neurosci. Lett."},{"issue":"29","key":"10.1016\/j.neulet.2022.136940_b0160","doi-asserted-by":"crossref","first-page":"9687","DOI":"10.1523\/JNEUROSCI.23-29-09687.2003","article-title":"Sleep deprivation causes behavioral, synaptic, and membrane excitability alteration in hippocampal neurons","volume":"23","author":"McDermott","year":"2003","journal-title":"J. Neuroscience"},{"key":"10.1016\/j.neulet.2022.136940_b0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2011.08.078","article-title":"Sleep loss alters synaptic and intrinsic neuronal properties in mouse prefrontal cortex","volume":"1420","author":"Winters","year":"2011","journal-title":"Brain Res."},{"issue":"9","key":"10.1016\/j.neulet.2022.136940_b0170","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1038\/mp.2010.89","article-title":"Sex differences in corticotropin-releasing factor receptor signaling and trafficking: potential role in female vulnerability to stress-related psychopathology","volume":"15","author":"Bangasser","year":"2010","journal-title":"Mol. Psychiatry"},{"issue":"1-2","key":"10.1016\/j.neulet.2022.136940_b0175","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0167-0115(00)00231-7","article-title":"Estrogen and androgen influence hypothalamic AVP and CRF concentrations in fetal and adult sheep","volume":"98","author":"Wood","year":"2001","journal-title":"Regul. Pept."},{"key":"10.1016\/j.neulet.2022.136940_b0180","doi-asserted-by":"crossref","unstructured":"J. Liu, P.H. Bisschop, L. Eggels, E. Foppen, E. Fliers, J.N. Zhou, A. Kalsbeek. (2012). Intrahypothalamic estradiol modulates hypothalamus-pituitary-adrenal-axis activity in female rats. Endocrinology. 2012 Jul;153(7):3337-44. doi: 10.1210\/en.2011-2176. Epub 2012 May 4. PMID: 22562172.","DOI":"10.1210\/en.2011-2176"},{"issue":"11","key":"10.1016\/j.neulet.2022.136940_b0185","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1159\/000338397","article-title":"Estrogen receptors and the regulation of neural stress response","volume":"96","author":"Handa","year":"2012","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neulet.2022.136940_b0195","doi-asserted-by":"crossref","DOI":"10.3389\/fnsyn.2021.804898","article-title":"Blast-Induced Mild Traumatic Brain Injury Alterations of Corticotropin-Releasing Factor Neuronal Activity in the Mouse Hypothalamic Paraventricular Nucleus","volume":"13","author":"Simmons","year":"2022","journal-title":"Front. Synaptic Neurosci."},{"issue":"5","key":"10.1016\/j.neulet.2022.136940_b0200","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/nn.3373","article-title":"Noradrenaline is a stress-associated metaplastic signal at GABA synapses","volume":"16","author":"Inoue","year":"2013","journal-title":"Nat. Neurosci."},{"issue":"12","key":"10.1016\/j.neulet.2022.136940_b0205","doi-asserted-by":"crossref","first-page":"4769","DOI":"10.1210\/en.2015-1673","article-title":"Diversity of Reporter Expression Patterns in Transgenic Mouse Lines Targeting Corticotropin-Releasing Hormone-Expressing Neurons","volume":"156","author":"Chen","year":"2015","journal-title":"Endocrinology"},{"key":"10.1016\/j.neulet.2022.136940_b0210","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.neuropharm.2018.09.037","article-title":"The effect of acute or repeated stress on the corticotropin releasing factor system in the CRH-IRES-Cre mouse: A validation study","volume":"154","author":"Walker","year":"2019","journal-title":"Neuropharmacology"},{"issue":"6","key":"10.1016\/j.neulet.2022.136940_b0215","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1159\/000123111","article-title":"Paraventricular nucleus: a site for the integration of neuroendocrine and autonomic mechanisms","volume":"31","author":"Swanson","year":"1980","journal-title":"Neuroendocrinology"},{"issue":"1","key":"10.1016\/j.neulet.2022.136940_b0220","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/0006-8993(80)90354-6","article-title":"PE Sawchenko, SJ Wiegand, JL Price (1980) Separate neurons in the paraventricular nucleus project to the median eminence and to the medulla or spinal cord","volume":"198","author":"Swanson","year":"1980","journal-title":"Brain Res."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394022005018?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394022005018?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T00:46:39Z","timestamp":1759625199000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394022005018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":43,"alternative-id":["S0304394022005018"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2022.136940","relation":{},"ISSN":["0304-3940"],"issn-type":[{"type":"print","value":"0304-3940"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alterations in the activation of corticotropin-releasing factor neurons in the paraventricular nucleus following a single or multiple days of sleep restriction","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2022.136940","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"136940"}}