{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:34:07Z","timestamp":1789180447644,"version":"build-2803163510"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.neulet.2023.137099","type":"journal-article","created":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T02:14:57Z","timestamp":1674872097000},"page":"137099","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["The brainstem connections of the supplementary motor area and its relations to the corticospinal tract: Experimental rat and human 3-tesla tractography study"],"prefix":"10.1016","volume":"798","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8847-9882","authenticated-orcid":false,"given":"Safiye","family":"\u00c7avdar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00fc\u015fra","family":"K\u00f6se","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damlasu","family":"Alt\u0131n\u00f6z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazhar","family":"\u00d6zkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasin Celal","family":"G\u00fcne\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oktay","family":"Alg\u0131n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2023.137099_b0005","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1016\/j.neuroimage.2009.10.016","article-title":"Defining functional SMA and pre-SMA subregions in human MFC using resting state fMRI: Functional connectivity-based parcellation method","volume":"49","author":"Kim","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.neulet.2023.137099_b0010","doi-asserted-by":"crossref","first-page":"3656","DOI":"10.1523\/JNEUROSCI.11-11-03656.1991","article-title":"Functional organization of human supplementary motor cortex studied by electrical stimulation","volume":"11","author":"Fried","year":"1991","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0015","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/cne.903110403","article-title":"Multiple representations of body movements in mesial area 6 and the adjacent cingulate cortex: An intracortical microstimulation study in the macaque monkey","volume":"311","author":"Luppino","year":"1991","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neulet.2023.137099_b0020","series-title":"Physiology","author":"Yip","year":"2021"},{"key":"10.1016\/j.neulet.2023.137099_b0025","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.neubiorev.2016.10.033","article-title":"Supplementary motor area as key structure for domain-general sequence processing: A unified account","volume":"72","author":"Cona","year":"2017","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neulet.2023.137099_b0030","doi-asserted-by":"crossref","unstructured":"J.R. Russell, W. DeMyer, The quantitative cortical origin of pyramidal axons of Macaca rhesus, Neurology. 11 (1961) 96\u201396. 10.1212\/wnl.11.2.96.","DOI":"10.1212\/WNL.11.2.96"},{"key":"10.1016\/j.neulet.2023.137099_b0035","first-page":"257","article-title":"Exact cortical extent of the origin of the corticospinal tract (CST) and the quantitative contribution to the CST in different cytoarchitectonic areas. A study with horseradish peroxidase in the monkey","volume":"23","author":"Toyoshima","year":"1982","journal-title":"J. Hirnforsch."},{"key":"10.1016\/j.neulet.2023.137099_b0040","doi-asserted-by":"crossref","unstructured":"R.P. Dum, P.L. Strick, Cingulate motor areas, Neurobiology of Cingulate Cortex and Limbic Thalamus. (1993) 415\u2013441. 10.1007\/978-1-4899-6704-6_15.","DOI":"10.1007\/978-1-4899-6704-6_15"},{"key":"10.1016\/j.neulet.2023.137099_b0045","first-page":"57","article-title":"Corticospinal efferents of the supplementary sensorimotor area in relation to the primary motor area","volume":"70","author":"Wise","year":"1996","journal-title":"Adv. Neurol."},{"key":"10.1016\/j.neulet.2023.137099_b0050","doi-asserted-by":"crossref","first-page":"6513","DOI":"10.1523\/JNEUROSCI.16-20-06513.1996","article-title":"Spinal cord terminations of the medial wall motor areas in macaque monkeys","volume":"16","author":"Dum","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0055","first-page":"679","article-title":"Are movement parameters recognizably coded in the activity of single neurons?","volume":"15","author":"Fetz","year":"1992","journal-title":"Behav. Brain Sci."},{"key":"10.1016\/j.neulet.2023.137099_b0060","first-page":"1","article-title":"Recent developments in studies of the supplementary motor area of primates","volume":"103","author":"Wiesendanger","year":"1986","journal-title":"Rev. Physiol. Biochem. Pharmacol."},{"key":"10.1016\/j.neulet.2023.137099_b0065","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0306-4522(98)00348-0","article-title":"Neural activity of supplementary and primary motor areas in monkeys and its relation to bimanual and unimanual movement sequences","volume":"89","author":"Kazennikov","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2023.137099_b0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.eplepsyres.2017.04.002","article-title":"Microstructural alterations of white matter in juvenile myoclonic epilepsy","volume":"135","author":"Gong","year":"2017","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.neulet.2023.137099_b0075","first-page":"3962","article-title":"Supplementary and Premotor Aspects of the Corticospinal Tract Show Links with Restricted and Repetitive Behaviors in Middle-Aged Adults with Autism Spectrum Disorder","volume":"31","author":"Hau","year":"2021","journal-title":"Cereb. Cortex"},{"issue":"3","key":"10.1016\/j.neulet.2023.137099_b0080","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1523\/JNEUROSCI.11-03-00667.1991","article-title":"The Origin of Corticospinal Projections from the Premotor Areas in the Frontal Lobe","volume":"11","author":"Dum","year":"1991","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0085","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/cne.903380109","article-title":"Corticocortical connections of area F3 (SMA-proper) and area F6 (pre-SMA) in the macaque monkey","volume":"338","author":"Luppino","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neulet.2023.137099_b0090","doi-asserted-by":"crossref","first-page":"10659","DOI":"10.1523\/JNEUROSCI.3134-07.2007","article-title":"Supplementary motor area and presupplementary motor area: Targets of basal ganglia and cerebellar output","volume":"27","author":"Akkal","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0095","unstructured":"G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2006."},{"key":"10.1016\/j.neulet.2023.137099_b0100","unstructured":"Laboratory for Computational Neuroimaging at the Athinoula A. Martinos Center for Biomedical Imaging, Free surfer wiki. https:\/\/freesurfer.net\/fswiki\/freesurferwiki\/ (accessed October 25, 2022)."},{"key":"10.1016\/j.neulet.2023.137099_b0105","unstructured":"F.O.U. Analysis Group, FMRIB software library v6.0, FSL. https:\/\/fsl.fmrib.ox.ac.uk\/fsl\/fslwiki\/ (accessed October 25, 2022)."},{"key":"10.1016\/j.neulet.2023.137099_b0110","unstructured":"MGH\/HST Martinos Center for Biomedical Imaging, Harvard ascending arousal network atlas. https:\/\/www.nmr.mgh.harvard.edu\/resources\/aan-atlas (accessed October 25, 2022)."},{"key":"10.1016\/j.neulet.2023.137099_b0115","unstructured":"Human connectome, brain image data, (n.d.). https:\/\/brain.labsolver.org\/diffusion-mri-templates\/hcp-842-hcp-1021 (accessed October 25, 2022)."},{"key":"10.1016\/j.neulet.2023.137099_b0120","unstructured":"U. de B. Institut des Maladies Neurod\u00e9g\u00e9n\u00e9ratives, Groupe d\u2019imagerie neurofonctionnelle (GIN-IMN). https:\/\/www.gin.cnrs.fr\/fr\/ (accessed October 25, 2022)."},{"key":"10.1016\/j.neulet.2023.137099_b0125","unstructured":"DSI-Studio: A Tractography Software Tool for Diffusion MRI Analysis | DSI Studio Documentation, Version 2022. https:\/\/dsi-studio.labsolver.org\/ (accessed January 2, 2023)."},{"key":"10.1016\/j.neulet.2023.137099_b0130","series-title":"Duvernoy\u2019s Atlas of the Human Brain Stem and Cerebellum","year":"2009"},{"key":"10.1016\/j.neulet.2023.137099_b0135","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1089\/brain.2011.0033","article-title":"Tractography: Where do we go from here?","volume":"1","author":"Jbabdi","year":"2011","journal-title":"Brain Connect."},{"key":"10.1016\/j.neulet.2023.137099_b0140","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00429-019-01985-8","article-title":"Fiber dissection and 3-tesla diffusion tensor tractography of the superior cerebellar peduncle in the human brain: emphasize on the cerebello-hypthalamic fibers","volume":"225","author":"\u00c7avdar","year":"2020","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.neulet.2023.137099_b0145","doi-asserted-by":"crossref","first-page":"6323","DOI":"10.1523\/JNEUROSCI.0403-18.2018","article-title":"Hand motor recovery following extensive frontoparietal cortical injury Is accompanied by upregulated corticoreticular projections in monkey","volume":"38","author":"Darling","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0150","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0006-8993(84)91341-6","article-title":"The efferent and afferent connections of the supplementary motor area","volume":"300","author":"J\u00fcrgens","year":"1984","journal-title":"Brain Res."},{"key":"10.1016\/j.neulet.2023.137099_b0155","doi-asserted-by":"crossref","DOI":"10.3389\/fnana.2019.00055","article-title":"Editorial: The functional anatomy of the reticular formation","volume":"13","author":"Faraguna","year":"2019","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.neulet.2023.137099_b0160","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0306-4522(00)00099-3","article-title":"Organization of somatic motor inputs from the frontal lobe to the pedunculopontine tegmental nucleus in the macaque monkey","volume":"98","author":"Matsumura","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2023.137099_b0165","article-title":"Connections of the nucleus tegmenti pedunculopontinis, pars compacta (TPc) in cat","volume":"196","author":"Moonedley","year":"1980","journal-title":"Anat. Rec."},{"key":"10.1016\/j.neulet.2023.137099_b0170","doi-asserted-by":"crossref","first-page":"4397","DOI":"10.1002\/hbm.25962","article-title":"In vivo structural connectome of arousal and motor brainstem nuclei by 7 Tesla and 3 Tesla MRI","volume":"43","author":"Garc\u00eda-Gomar","year":"2022","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neulet.2023.137099_b0175","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1002\/mds.26923","article-title":"Pedunculopontine network dysfunction in Parkinson\u2019s disease with postural control and sleep disorders","volume":"32","author":"Gallea","year":"2017","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neulet.2023.137099_b0180","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2018.00099","article-title":"A review of the pedunculopontine nucleus in Parkinson\u2019s disease","volume":"10","author":"French","year":"2018","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0185","doi-asserted-by":"crossref","DOI":"10.1007\/s00415-022-11294-6","article-title":"Associated factors and abnormal dorsal raphe nucleus connectivity patterns of freezing of gait in Parkinson\u2019s disease","author":"Lv","year":"2022","journal-title":"J. Neurol."},{"key":"10.1016\/j.neulet.2023.137099_b0190","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.biopsych.2017.08.021","article-title":"Locus coeruleus activity mediates hyperresponsiveness in posttraumatic stress disorder","volume":"83","author":"Naegeli","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2023.137099_b0195","doi-asserted-by":"crossref","first-page":"3484","DOI":"10.1523\/JNEUROSCI.1361-21.2022","article-title":"Prefrontal Cortical Connectivity Mediates Locus Coeruleus Noradrenergic Regulation of Inhibitory Control in Older Adults","volume":"42","author":"Tomassini","year":"2022","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0200","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1007\/s00429-019-01939-0","article-title":"Ventral tegmental area connections to motor and sensory cortical fields in humans","volume":"224","author":"Hosp","year":"2019","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.neulet.2023.137099_b0205","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.neulet.2012.07.012","article-title":"Basal ganglia circuits changes in Parkinson\u2019s disease patients","volume":"524","author":"Wu","year":"2012","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2023.137099_b0210","doi-asserted-by":"crossref","unstructured":"F.A., Middleton, P.L. Strick, Basal-ganglia \u201cprojections\u201d to the prefrontal cortex of the primate, Brain Res. Rev. 31 (2000) 236\u2013250. 10.1016\/s0165-0173(99)00040-5.","DOI":"10.1016\/S0165-0173(99)00040-5"},{"issue":"4","key":"10.1016\/j.neulet.2023.137099_b0215","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00221-001-0894-7","article-title":"Vestibular projections in the human cortex","volume":"141","author":"Waele","year":"2001","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.neulet.2023.137099_b0220","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1196\/annals.1325.012","article-title":"Saccular projections in the human cerebral cortex","volume":"1039","author":"Miyamoto","year":"2005","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neulet.2023.137099_b0225","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1159\/000080228","article-title":"Cortical activation shortly after cochlear implantation","volume":"9","author":"Ito","year":"2004","journal-title":"Audiol. Neurotol."},{"key":"10.1016\/j.neulet.2023.137099_b0230","doi-asserted-by":"crossref","first-page":"8432","DOI":"10.1523\/JNEUROSCI.23-23-08432.2003","article-title":"Cerebellar loops with motor cortex and prefrontal cortex of a nonhuman primate","volume":"23","author":"Kelly","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0235","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1523\/JNEUROSCI.15-05-03284.1995","article-title":"Topographic organization of corticospinal projections from the frontal lobe: motor areas on the medial surface of the hemisphere","volume":"15","author":"He","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2023.137099_b0240","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/cercor\/12.3.281","article-title":"Differences in the corticospinal projection from primary motor cortex and supplementary motor area to macaque upper limb motoneurons: An anatomical and electrophysiological study","volume":"12","author":"Maier","year":"2002","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neulet.2023.137099_b0245","doi-asserted-by":"crossref","unstructured":"F. Brugger, R. Wegener, F. Baty, J. Walch, M.T. Kr\u00fcger, S. H\u00e4gele-Link, S. Bohlhalter, G. K\u00e4gi, Facilitatory rTMS over the supplementary motor cortex impedes gait performance in Parkinson Patients with freezing of gait, Brain Sciences 2021, Vol. 11, Page 321. 11 (2021) 321. 10.3390\/brainsci11030321.","DOI":"10.3390\/brainsci11030321"},{"key":"10.1016\/j.neulet.2023.137099_b0250","article-title":"Altered cerebral blood flow in Alzheimer\u2019s disease with depression","volume":"12","author":"Li","year":"2021","journal-title":"Front. Psychiatry."},{"key":"10.1016\/j.neulet.2023.137099_b0255","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2021.766736","article-title":"Potential locations for non-invasive brain stimulation in treating schizophrenia: A resting-state functional connectivity analysis","volume":"12","author":"Ning","year":"2021","journal-title":"Front. Neurol."},{"key":"10.1016\/j.neulet.2023.137099_b0260","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.neurobiolaging.2019.09.018","article-title":"Impaired motor skills and atypical functional connectivity of the sensorimotor system in 40- to 65-year-old adults with autism spectrum disorders","volume":"85","author":"Linke","year":"2020","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neulet.2023.137099_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.pscychresns.2022.111578","article-title":"Abnormal amygdala functional connectivity in MDD patients with insomnia complaints","volume":"328","author":"Ye","year":"2023","journal-title":"Psychiatry Res. Neuroimaging."},{"key":"10.1016\/j.neulet.2023.137099_b0270","article-title":"Dynamic hippocampal functional connectivity responses to varying working memory loads following total sleep deprivation","volume":"e13797","author":"Wang","year":"2022","journal-title":"J. Sleep Res."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394023000538?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394023000538?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T00:47:17Z","timestamp":1759625237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394023000538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":54,"alternative-id":["S0304394023000538"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2023.137099","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The brainstem connections of the supplementary motor area and its relations to the corticospinal tract: Experimental rat and human 3-tesla tractography study","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2023.137099","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"137099"}}