{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T20:53:37Z","timestamp":1794430417872,"version":"4.9.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.neulet.2023.137264","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T16:49:23Z","timestamp":1682009363000},"page":"137264","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Folate deprivation induced neuroinflammation impairs cognition"],"prefix":"10.1016","volume":"807","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3931-8668","authenticated-orcid":false,"given":"Afridi","family":"Shaikh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7899-1930","authenticated-orcid":false,"given":"Hetal","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.neulet.2023.137264_b0005","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/nrneurol.2014.181","article-title":"Classifying neurocognitive disorders: the DSM-5 approach","volume":"10","author":"Sachdev","year":"2014","journal-title":"Nat. Rev. Neurol."},{"issue":"3","key":"10.1016\/j.neulet.2023.137264_b0010","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S1474-4422(19)30411-9","article-title":"The global burden of neurological disorders: translating evidence into policy","volume":"19","author":"Feigin","year":"2020","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neulet.2023.137264_b0015","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1474-4422(18)30499-X","article-title":"Global, regional, and national burden of neurological disorders, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"Feigin","year":"2019","journal-title":"Lancet Neurol."},{"issue":"6","key":"10.1016\/j.neulet.2023.137264_b0020","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/ajcn\/nqz023","article-title":"Improved micronutrient status and health outcomes in low- and middle-income countries following large-scale fortification: evidence from a systematic review and meta-analysis","volume":"109","author":"Keats","year":"2019","journal-title":"Am. J. Clin. Nutr."},{"issue":"7","key":"10.1016\/j.neulet.2023.137264_b0025","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/nrn2421","article-title":"Brain foods: the effects of nutrients on brain function","volume":"9","author":"G\u00f3mez-Pinilla","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0030","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1017\/S0029665114001554","article-title":"Emerging roles for folate and related B-vitamins in brain health across the lifecycle","volume":"74","author":"McGarel","year":"2015","journal-title":"Proc. Nutr. Soc."},{"issue":"15","key":"10.1016\/j.neulet.2023.137264_b0035","first-page":"385","article-title":"The association between folate and Alzheimer\u2019s disease: a systematic review and meta-analysis","volume":"14","author":"Zhang","year":"2021","journal-title":"Front. Neurosci."},{"issue":"2","key":"10.1016\/j.neulet.2023.137264_b0040","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s11011-009-9139-4","article-title":"Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson\u2019s disease","volume":"24","author":"dos Santos","year":"2009","journal-title":"Metab. Brain Dis."},{"issue":"8","key":"10.1016\/j.neulet.2023.137264_b0045","doi-asserted-by":"crossref","first-page":"3340","DOI":"10.1021\/acschemneuro.9b00333","article-title":"Understanding the Role of systemic inflammation in Alzheimer\u2019s disease","volume":"10","author":"Walker","year":"2019","journal-title":"ACS Chem. Nerosci."},{"issue":"7","key":"10.1016\/j.neulet.2023.137264_b0050","doi-asserted-by":"crossref","first-page":"4795","DOI":"10.1111\/jcmm.14368","article-title":"Folic acid deficiency enhanced microglial immune response via the Notch1\/nuclear factor kappa B p65 pathway in hippocampus following rat brain I\/R injury and BV2 cells","volume":"23","author":"Cheng","year":"2019","journal-title":"J. Cell Mol. Med."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0055","first-page":"1","article-title":"NF-\u03baB signaling in inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct Targeted Ther"},{"issue":"17","key":"10.1016\/j.neulet.2023.137264_b0060","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1016\/0006-2952(74)90235-4","article-title":"A fluorometric micromethod for the simultaneous determination of serotonin, noradrenaline and dopamine in milligram amounts of brain tissue","volume":"23","author":"Schlumpf","year":"1974","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0065","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.neuron.2012.09.013","article-title":"Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders","volume":"76","author":"Lesch","year":"2012","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.neulet.2023.137264_b0070","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s00221-013-3818-4","article-title":"The role of serotonin in memory: interactions with neurotransmitters and downstream signaling","volume":"232","author":"Seyedabadi","year":"2014","journal-title":"Exp. Brain Res."},{"issue":"22","key":"10.1016\/j.neulet.2023.137264_b0075","doi-asserted-by":"crossref","first-page":"9511","DOI":"10.1073\/pnas.0701055104","article-title":"Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies","volume":"104","author":"Luo","year":"2007","journal-title":"PNAS"},{"key":"10.1016\/j.neulet.2023.137264_b0080","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.expneurol.2014.04.033","article-title":"Systemic inflammation is associated with a reduction in Synaptopodin expression in the mouse hippocampus","volume":"261","author":"Strehl","year":"2014","journal-title":"Exp. Neurol."},{"issue":"7","key":"10.1016\/j.neulet.2023.137264_b0085","doi-asserted-by":"crossref","first-page":"622","DOI":"10.2174\/1567205016666190725144629","article-title":"Effects of folic acid and vitamin B12, alone and in combination on cognitive function and inflammatory factors in the elderly with mild cognitive impairment: a single-blind experimental design","volume":"16","author":"Ma","year":"2019","journal-title":"Curr. Alzheimer Res."},{"issue":"4","key":"10.1016\/j.neulet.2023.137264_b0090","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1093\/nutrit\/nuab057","article-title":"B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis","volume":"80","author":"Wang","year":"2022","journal-title":"Nutr. Rev."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0095","article-title":"Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1. Clin","volume":"11","author":"An","year":"2019","journal-title":"Epigenetics"},{"key":"10.1016\/j.neulet.2023.137264_b0100","unstructured":"Neradil J, Pavlasova G, Veselska R. New mechanisms for an old drug; DHFR- and non-DHFR-mediated effects of methotrexate in cancer cells. Klinicka Onkologie: casopis Ceske a Slovenske Onkologicke Spolecnosti. 2012 ;25 Suppl 2:2S87-92. PMID: 23581023."},{"key":"10.1016\/j.neulet.2023.137264_b0105","doi-asserted-by":"crossref","DOI":"10.3945\/ajcn.110.005736","article-title":"Contribution made by biomarkers of status to an FP6 Network of Excellence, EURopean micronutrient RECommendations Aligned (EURRECA)","author":"Fairweather-Tait","year":"2011","journal-title":"Am. J. Clin. Nutr."},{"issue":"404","key":"10.1016\/j.neulet.2023.137264_b0110","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.neuroscience.2019.01.024","article-title":"Methotrexate affects cerebrospinal fluid folate and tau levels and induces late cognitive deficits in mice","volume":"15","author":"Elens","year":"2019","journal-title":"Neuroscience"},{"issue":"1527","key":"10.1016\/j.neulet.2023.137264_b0115","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.brainres.2013.06.033","article-title":"Behavioral effects of bidirectional modulators of brain monoamines reserpine and d-amphetamine in zebrafish","volume":"21","author":"Kyzar","year":"2013","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.neulet.2023.137264_b0120","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1176\/appi.ajp.2015.15020162","article-title":"Depression-related increases and decreases in appetite: Dissociable patterns of aberrant activity in reward and interoceptive neurocircuitry","volume":"173","author":"Simmons","year":"2016","journal-title":"Am J Psychiatry"},{"issue":"10","key":"10.1016\/j.neulet.2023.137264_b0125","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1038\/sj.npp.1300506","article-title":"Discovering endophenotypes for major depression","volume":"29","author":"Hasler","year":"2004","journal-title":"Neuropsychopharmacology"},{"issue":"95","key":"10.1016\/j.neulet.2023.137264_b0130","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jpsychires.2017.07.019","article-title":"The association of folate and depression: a meta-analysis","volume":"1","author":"Bender","year":"2017","journal-title":"J. Psychiatr. Res."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0135","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-019-11876-5","article-title":"Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors","volume":"10","author":"Gorinski","year":"2019","journal-title":"Nat. Commun."},{"issue":"7433","key":"10.1016\/j.neulet.2023.137264_b0140","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/nature11740","article-title":"Dopamine neurons modulate neural encoding and expression of depression-related behaviour","volume":"493","author":"Tye","year":"2013","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.neulet.2023.137264_b0145","doi-asserted-by":"crossref","first-page":"1568S","DOI":"10.1093\/jn\/137.6.1568S","article-title":"Inherited disorders affecting dopamine and serotonin: critical neurotransmitters derived from aromatic amino acids","volume":"137","author":"Hyland","year":"2007","journal-title":"J Nutr."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0150","first-page":"1","article-title":"Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice","volume":"9","author":"Zhao","year":"2019","journal-title":"Sci. Rep."},{"issue":"2\u20134","key":"10.1016\/j.neulet.2023.137264_b0155","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/B978-0-12-375083-9.00144-6","article-title":"Homocysteine","volume":"1","author":"Miller","year":"2013","journal-title":"Encycl Hum Nutr"},{"key":"10.1016\/j.neulet.2023.137264_b0160","doi-asserted-by":"crossref","unstructured":"Barroso M, Handy DE, Castro R. The Link Between Hyperhomocysteinemia and Hypomethylation: Implications for Cardiovascular Disease. 2017 Apr 5;5:232640981769899. https:\/\/journals.sagepub.com\/doi\/10.1177\/2326409817698994.","DOI":"10.1177\/2326409817698994"},{"issue":"2","key":"10.1016\/j.neulet.2023.137264_b0165","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/cvr\/cvq076","article-title":"The nuclear factor-\u03baB\u2013interleukin-6 signalling pathway mediating vascular inflammation","volume":"86","author":"Brasier","year":"2010","journal-title":"Cardiovasc Res."},{"issue":"10","key":"10.1016\/j.neulet.2023.137264_b0170","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1161\/01.ATV.0000029781.31325.66","article-title":"Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women","volume":"22","author":"Bermudez","year":"2002","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12979-016-0076-x","article-title":"Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study","volume":"13","author":"Puzianowska-Ku\u017anicka","year":"2016","journal-title":"Immun. Ageing"},{"issue":"9","key":"10.1016\/j.neulet.2023.137264_b0180","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.it.2016.06.006","article-title":"Astrocytes: key regulators of neuroinflammation","volume":"37","author":"Colombo","year":"2016","journal-title":"Trends Immunol."},{"issue":"12","key":"10.1016\/j.neulet.2023.137264_b0185","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1002\/glia.23849","article-title":"Radial glia in the zebrafish brain: Functional, structural, and physiological comparison with the mammalian glia","volume":"68","author":"Jurisch-Yaksi","year":"2020","journal-title":"Glia"},{"key":"10.1016\/j.neulet.2023.137264_b0190","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.cbi.2019.02.013","article-title":"Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression","volume":"302","author":"Krupenko","year":"2019","journal-title":"Chem. Biol. Interact."},{"issue":"1\u20132","key":"10.1016\/j.neulet.2023.137264_b0195","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jns.2007.08.044","article-title":"Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders","volume":"267","author":"de Keyser","year":"2008","journal-title":"J. Neurol. Sci."},{"issue":"4","key":"10.1016\/j.neulet.2023.137264_b0200","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/mds.21751","article-title":"Glial reactions in Parkinson\u2019s disease","volume":"23","author":"McGeer","year":"2008","journal-title":"Movem Disord"},{"key":"10.1016\/j.neulet.2023.137264_b0205","doi-asserted-by":"crossref","unstructured":"Lattke M, Wirth T, Lattke M, Wirth T. Signaling Pathways Regulating the Pathophysiological Responses of Astrocytes: A Focus on the IKK\/NF-\u03baB System. Astrocyte - Physiology and Pathology. 2017 Dec 20; https:\/\/www.intechopen.com\/state.item.id.","DOI":"10.5772\/intechopen.72283"},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1750-1326-7-47","article-title":"IB deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery","volume":"7","author":"Lian","year":"2012","journal-title":"Mol. Neurodegener."},{"issue":"10","key":"10.1016\/j.neulet.2023.137264_b0215","doi-asserted-by":"crossref","first-page":"6404","DOI":"10.4049\/jimmunol.178.10.6404","article-title":"Cytoskeletal protein transformation in HIV-1-infected macrophage giant cells","volume":"178","author":"Kadiu","year":"2007","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.neulet.2023.137264_b0220","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.4103\/1673-5374.237109","article-title":"Role of nuclear factor \u03baB in multiple sclerosis and experimental autoimmune encephalomyelitis","volume":"13","author":"Yue","year":"2018","journal-title":"Neural Regen Res."},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0225","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/nn.4193","article-title":"Oligodendrocyte death results in immune-mediated CNS demyelination","volume":"19","author":"Traka","year":"2016","journal-title":"Nat. Neurosci."},{"issue":"14","key":"10.1016\/j.neulet.2023.137264_b0230","first-page":"458","article-title":"Strategies for oligodendrocyte and myelin repair in traumatic CNS injury","volume":"11","author":"Huntemer-Silveira","year":"2021","journal-title":"Front. Cell. Neurosci."},{"issue":"3","key":"10.1016\/j.neulet.2023.137264_b0235","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0304-4165(02)00410-5","article-title":"Galactolipids are molecular determinants of myelin development and axo-glial organization","volume":"1573","author":"Marcus","year":"2002","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"issue":"5\u20136","key":"10.1016\/j.neulet.2023.137264_b0240","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00335-019-09802-7","article-title":"Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis","volume":"30","author":"Gunn","year":"2019","journal-title":"Mamm. Genome"},{"issue":"12","key":"10.1016\/j.neulet.2023.137264_b0245","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.bbadis.2008.08.006","article-title":"The ubiquitin\u2013proteasome system in spongiform degenerative disorders","volume":"1782","author":"Whatley","year":"2008","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"issue":"58","key":"10.1016\/j.neulet.2023.137264_b0250","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.cortex.2014.05.001","article-title":"Neuroplasticity as a function of second language learning: anatomical changes in the human brain","volume":"1","author":"Li","year":"2014","journal-title":"Cortex"},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40893-017-0019-1","article-title":"Hippocampal neuroplasticity and inflammation: relevance for multiple sclerosis","volume":"2","author":"Mancini","year":"2017","journal-title":"Mult Scler Demyelinat Disord"},{"issue":"6","key":"10.1016\/j.neulet.2023.137264_b0260","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1038\/ki.2014.428","article-title":"Fine-tuning of NF\u03baB by Glycogen Synthase Kinase 3\u03b2 directs the fate of glomerular podocytes upon injury","volume":"87","author":"Bao","year":"2015","journal-title":"Kidney Int."},{"issue":"8","key":"10.1016\/j.neulet.2023.137264_b0265","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s11910-022-01207-5","article-title":"Neurodegeneration and neuroinflammation in Parkinson\u2019s disease: a self-sustained loop","volume":"22","author":"Arena","year":"2022","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"5","key":"10.1016\/j.neulet.2023.137264_b0270","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3390\/biomedicines9050524","article-title":"Neuroinflammation in Alzheimer\u2019s Disease","volume":"9","author":"Onyango","year":"2021","journal-title":"Biomedicines"},{"issue":"13","key":"10.1016\/j.neulet.2023.137264_b0275","first-page":"230","article-title":"The Q336H MAPT mutation linked to Pick\u2019s disease leads to increased binding of tau to the microtubule network via altered conformational and phosphorylation effects","volume":"2","author":"Siano","year":"2020","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.neulet.2023.137264_b0280","doi-asserted-by":"crossref","unstructured":"Bohush A, Bieganowski P, Filipek A. Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases. Int J Mol Sci. 2019 Oct 2;20(20). https:\/\/pubmed.ncbi.nlm.nih.gov\/31600883\/.","DOI":"10.3390\/ijms20204976"},{"issue":"1","key":"10.1016\/j.neulet.2023.137264_b0285","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.pneurobio.2010.10.006","article-title":"Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer\u2019s disease","volume":"93","author":"Salminen","year":"2011","journal-title":"Prog. Neurobiol."},{"issue":"12","key":"10.1016\/j.neulet.2023.137264_b0290","doi-asserted-by":"crossref","first-page":"338","DOI":"10.3389\/fncel.2018.00338","article-title":"Hyperphosphorylation of Tau Associates with changes in its function beyond microtubule stability","volume":"9","author":"Alonso","year":"2018","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.neulet.2023.137264_b0295","doi-asserted-by":"crossref","unstructured":"Mollapour M, Neckers L. Post-translational modifications of Hsp90 and their contributions to chaperone regulation. Biochim Biophys Acta. 2012 Mar;1823(3):648. \/pmc\/articles\/PMC3226900\/.","DOI":"10.1016\/j.bbamcr.2011.07.018"},{"key":"10.1016\/j.neulet.2023.137264_b0300","unstructured":"Wang C, Fan L, Khawaja RR, Liu B, Zhan L, Kodama L, et al. Microglial NF-\u03baB drives tau spreading and toxicity in a mouse model of tauopathy. Nature Communications 2022 13:1. 2022 Apr 12;13(1):1\u201319. https:\/\/www.nature.com\/articles\/s41467-022-29552-6."},{"key":"10.1016\/j.neulet.2023.137264_b0305","doi-asserted-by":"crossref","unstructured":"Khandelwal N, Simpson J, Taylor G, Rafique S, Whitehouse A, Hiscox J, et al. Nucleolar NF-\u03baB\/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin. Cell Death & Differentiation 2011 18:12. 2011 Jun 10;18(12):1889\u2013903. https:\/\/www.nature.com\/articles\/cdd201179.","DOI":"10.1038\/cdd.2011.79"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394023002239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394023002239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T00:47:50Z","timestamp":1759625270000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394023002239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":61,"alternative-id":["S0304394023002239"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2023.137264","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Folate deprivation induced neuroinflammation impairs cognition","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neulet.2023.137264","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"137264"}}