{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:14:15Z","timestamp":1790187255154,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroradiology"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.neurad.2013.08.005","type":"journal-article","created":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T03:23:29Z","timestamp":1380597809000},"page":"202-210","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Accelerated myelination along fiber tracts in patients with hemimegalencephaly"],"prefix":"10.1016","volume":"41","author":[{"given":"Kouhei","family":"Kamiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimiteru","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Shigemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Ota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuni","family":"Ohtomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurad.2013.08.005_bib0005","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0887-8994(01)00318-6","article-title":"Radiologic-pathologic correlation in focal cortical dysplasia and hemimegalencephaly in 18 children","volume":"25","author":"Woo","year":"2001","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0010","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1177\/088307380201700512","article-title":"Hemimegalencephaly: part 1. Genetic, clinical, and imaging aspects","volume":"17","author":"Flores-Sarnat","year":"2002","journal-title":"J Child Neurol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0015","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1093\/brain\/aws019","article-title":"A developmental and genetic classification for malformations of cortical development: update 2012","volume":"135","author":"Barkovich","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.neurad.2013.08.005_bib0020","first-page":"523","article-title":"Unilateral megalencephaly: correlation of MR imaging and pathologic characteristics","volume":"11","author":"Barkovich","year":"1990","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0025","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1148\/radiology.165.1.3628788","article-title":"Hemimegalencephaly: MR imaging in five children","volume":"165","author":"Kalifa","year":"1987","journal-title":"Radiology"},{"key":"10.1016\/j.neurad.2013.08.005_bib0030","first-page":"678","article-title":"Hemimegalencephaly: a study of abnormalities occurring outside the involved hemisphere","volume":"28","author":"Sato","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0035","doi-asserted-by":"crossref","first-page":"823","DOI":"10.3174\/ajnr.A0919","article-title":"Aberrant midsagittal fiber tracts in patients with hemimegalencephaly","volume":"29","author":"Sato","year":"2008","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0040","first-page":"25","article-title":"Diffusion tensor MR imaging visualizes the altered hemispheric fiber connection in callosal dysgenesis","volume":"25","author":"Lee","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0045","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neurad.2011.12.002","article-title":"Diffusion tensor imaging localization of the pyramidal tract and spectroscopy in diencephalic pilocytic astrocytoma: a case report","volume":"40","author":"Knorr","year":"2013","journal-title":"J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0050","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1007\/s002340050674","article-title":"Hemimegalencephaly: signal changes suggesting abnormal myelination on MRI","volume":"40","author":"Yagishita","year":"1998","journal-title":"Neuroradiology"},{"key":"10.1016\/j.neurad.2013.08.005_bib0055","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.yebeh.2011.06.025","article-title":"Accelerated myelination with motor system involvement in a neonate with immediate postnatal onset of seizures and hemimegalencephaly","volume":"22","author":"Goldsberry","year":"2011","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.neurad.2013.08.005_bib0060","first-page":"459","article-title":"MR of fetal central nervous system abnormalities","volume":"15","author":"Yuh","year":"1994","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0065","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1055\/s-0032-1306382","article-title":"Assessment of normal myelination with magnetic resonance imaging","volume":"32","author":"Welker","year":"2012","journal-title":"Semin Neurol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0070","first-page":"1129","article-title":"Normal myelination of anatomic nerve fiber bundles: MR analysis","volume":"19","author":"Nakagawa","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0075","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/00005072-198805000-00003","article-title":"Sequence of central nervous system myelination in human infancy II. Patterns of myelination in autopsied infants","volume":"47","author":"Kinney","year":"1988","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0080","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0720-048X(02)00328-5","article-title":"MR diffusion tensor imaging: recent advance and new techniques for diffusion tensor visualization","volume":"46","author":"Masutani","year":"2003","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0085","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/1531-8249(199902)45:2<265::AID-ANA21>3.0.CO;2-3","article-title":"Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging","volume":"45","author":"Mori","year":"1999","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0090","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/s002340050648","article-title":"Focal seizure-induced premature myelination: speculation from serial MRI","volume":"40","author":"Duprez","year":"1998","journal-title":"Neuroradiology"},{"key":"10.1016\/j.neurad.2013.08.005_bib0095","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/mrm.1910370107","article-title":"In vivo measurement of T2 distributions and water contents in normal human brain","volume":"37","author":"Whittall","year":"1997","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.neurad.2013.08.005_bib0100","series-title":"Pediatric neuroimaging","first-page":"40","article-title":"Normal development of the neonatal and infant brain, skull, and spine","author":"Barkovich","year":"2012"},{"key":"10.1016\/j.neurad.2013.08.005_bib0105","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1523\/JNEUROSCI.2106-10.2011","article-title":"Mapping infant brain myelination with magnetic resonance imaging","volume":"31","author":"Deoni","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.neurad.2013.08.005_bib0110","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.neuroimage.2010.03.013","article-title":"The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models","volume":"51","author":"Dyakin","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.neurad.2013.08.005_bib0115","doi-asserted-by":"crossref","first-page":"9887","DOI":"10.1073\/pnas.93.18.9887","article-title":"Induction of myelination in the central nervous system by electrical activity","volume":"93","author":"Demerens","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.neurad.2013.08.005_bib0120","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0896-6273(02)01067-X","article-title":"Adenosine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials","volume":"36","author":"Stevens","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.neurad.2013.08.005_bib0125","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1080\/09647040600620468","article-title":"The complex history of the fronto-occipital fasciculus","volume":"16","author":"Schmahmann","year":"2007","journal-title":"J His Neurosci"},{"key":"10.1016\/j.neurad.2013.08.005_bib0130","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1148\/radiol.2301021640","article-title":"Fiber tract-based atlas of human white matter anatomy","volume":"230","author":"Wakana","year":"2004","journal-title":"Radiology"},{"key":"10.1016\/j.neurad.2013.08.005_bib0135","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1006\/nimg.2002.1136","article-title":"Virtual in vivo interactive dissection of white matter fasciculi in the human brain","volume":"17","author":"Catani","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.neurad.2013.08.005_bib0140","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.neuroimage.2007.05.042","article-title":"The occipitofrontal fascicle in humans: a quantitative, in vivo, DT-MRI study","volume":"37","author":"Makris","year":"2007","journal-title":"Neuroimage"},{"key":"10.1016\/j.neurad.2013.08.005_bib0145","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.pscychresns.2008.03.004","article-title":"Tract-specific analysis of the superior occipitofrontal fasciculus in schizophrenia","volume":"164","author":"Kunimatsu","year":"2008","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.neurad.2013.08.005_bib0150","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s00429-010-0279-4","article-title":"Prominent periventricular fiber system related to ganglionic eminence and striatum in the human fetal cerebrum","volume":"215","author":"Vasung","year":"2011","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.neurad.2013.08.005_bib0155","first-page":"2671","article-title":"Structural, immunocytochemical, and MR imaging properties of periventricular crossroads of growing cortical pathways in preterm infants","volume":"26","author":"Juda\u0161","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0160","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.neurad.2011.06.002","article-title":"Malformations of cortical development of the human brain: a pictorial essay","volume":"39","author":"Fitsiori","year":"2012","journal-title":"J Neuroradiol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0165","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.neuron.2012.03.010","article-title":"Somatic activation of AKT3 causes hemispheric developmental brain malformations","volume":"74","author":"Poduri","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neurad.2013.08.005_bib0170","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/ng.2329","article-title":"De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly","volume":"44","author":"Lee","year":"2012","journal-title":"Nat Genet"},{"key":"10.1016\/j.neurad.2013.08.005_bib0175","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/ng.2331","article-title":"De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes","volume":"44","author":"Riviere","year":"2012","journal-title":"Nat Genet"},{"key":"10.1016\/j.neurad.2013.08.005_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S031716710002610X","article-title":"Disorders of neuronal migration","volume":"14","author":"Barth","year":"1987","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.neurad.2013.08.005_bib0185","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0006-8993(68)90260-6","article-title":"Unilateral megalencephaly with nerve cell hypertrophy. An anatomical and quantitative histochemical study","volume":"9","author":"Bignami","year":"1968","journal-title":"Brain Res"},{"key":"10.1016\/j.neurad.2013.08.005_bib0190","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1177\/08830738030180111101","article-title":"Hemimegalencephaly: part 2. Neuropathology suggests a disorder of cellular lineage","volume":"18","author":"Flores-Sarnat","year":"2003","journal-title":"J Child Neurol"},{"key":"10.1016\/j.neurad.2013.08.005_bib0195","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1093\/brain\/awh681","article-title":"Contralateral hemimicrencephaly and clinical-pathological correlations in children with hemimegalencephaly","volume":"129","author":"Salamon","year":"2006","journal-title":"Brain"}],"container-title":["Journal of Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0150986113000849?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0150986113000849?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T10:39:31Z","timestamp":1758969571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0150986113000849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0150986113000849"],"URL":"https:\/\/doi.org\/10.1016\/j.neurad.2013.08.005","relation":{},"ISSN":["0150-9861"],"issn-type":[{"value":"0150-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Accelerated myelination along fiber tracts in patients with hemimegalencephaly","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroradiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurad.2013.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}