{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:05:12Z","timestamp":1759017912826,"version":"3.44.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroradiology"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.neurad.2016.10.005","type":"journal-article","created":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T23:45:19Z","timestamp":1481154319000},"page":"10-16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Diagnostic performance of CT cerebral blood volume colour maps for evaluation of acute infarcts; comparison with diffusion-weighted MRI within 12 hours of major stroke onset"],"prefix":"10.1016","volume":"44","author":[{"given":"Enas A.","family":"Abdelgawad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud M.","family":"Higazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelraouf O.","family":"Abdelbaky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hosny S.","family":"Abdelghany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurad.2016.10.005_bib0215","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1161\/01.STR.0000182100.65262.46","article-title":"Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies","volume":"36","author":"Molina","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0220","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1161\/01.STR.0000227243.96808.53","article-title":"Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion-derived blood flow and blood volume measurements","volume":"37","author":"Murphy","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0225","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1212\/01.wnl.0000255959.30107.08","article-title":"Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment","volume":"68","author":"Wintermark","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0230","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1136\/neurintsurg-2012-010404","article-title":"Low signal, high noise and large uncertainty make CT perfusion unsuitable for acute ischemic stroke patient selection for endovascular therapy","volume":"4","author":"Gonz\u00e1lez","year":"2012","journal-title":"J Neurointerv Surg"},{"key":"10.1016\/j.neurad.2016.10.005_bib0235","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1148\/radiology.217.2.r00nv24331","article-title":"Diffusion-weighted MR imaging of the brain","volume":"217","author":"Schaefer","year":"2000","journal-title":"Radiology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0240","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1212\/WNL.0b013e3181e7c9dd","article-title":"Evidence-based guideline: the role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology","volume":"75","author":"Schellinger","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0245","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/S1474-4422(12)70203-X","article-title":"MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study","volume":"11","author":"Lansberg","year":"2012","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0250","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1161\/STROKEAHA.113.003880","article-title":"Addition of hyperacute MRI AIDS in patient selection, decreasing the use of endovascular stroke therapy","volume":"45","author":"Wisco","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0255","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/ana.10136","article-title":"Prognostic accuracy of cerebral blood flow measurement by perfusion computed tomography, at the time of emergency room admission, in acute stroke patients","volume":"51","author":"Wintermark","year":"2002","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0260","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1161\/01.STR.0000023579.61630.AC","article-title":"Comparison of admission perfusion computed tomography and qualitative diffusion- and perfusion-weighted magnetic resonance imaging in acute stroke patients","volume":"33","author":"Wintermark","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0265","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1148\/radiology.209.1.9769817","article-title":"Perfusion CT of the brain: diagnostic approach for early detection of ischemic stroke","volume":"209","author":"Koenig","year":"1998","journal-title":"Radiology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0270","first-page":"1441","article-title":"Dynamic CT perfusion imaging of acute stroke","volume":"21","author":"Mayer","year":"2000","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0275","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1148\/radiol.2221010471","article-title":"CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke","volume":"222","author":"Eastwood","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neurad.2015.02.001","article-title":"Neuroradiology of acute stroke, where are we today?","volume":"42","author":"L\u00f6vblad","year":"2015","journal-title":"J Neuroradiol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0285","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.neurad.2008.01.002","article-title":"Neuro-imaging of cerebral ischemic stroke","volume":"35","author":"L\u00f6vblad","year":"2008","journal-title":"J Neuroradiol"},{"issue":"Suppl. 4","key":"10.1016\/j.neurad.2016.10.005_bib0290","doi-asserted-by":"crossref","first-page":"D28","DOI":"10.1007\/s10406-005-0112-y","article-title":"Brain perfusion-CT in acute stroke patients","volume":"15","author":"Wintermark","year":"2005","journal-title":"Eur Radiol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0295","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1161\/01.STR.0000032244.03134.37","article-title":"Comparison of CT and CT angiography source images with diffusion-weighted imaging in patients with acute stroke within 6 hours after onset","volume":"33","author":"Schramm","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0300","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.3174\/ajnr.A2026","article-title":"Evaluation of CT perfusion in the setting of cerebral ischemia: patterns and pitfalls","volume":"31","author":"Lui","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0305","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1161\/01.STR.0000209238.61459.39","article-title":"Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke","volume":"37","author":"Wintermark","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0310","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1007\/s00234-006-0105-0","article-title":"Impact of diffusion-weighted MRI-measured initial cerebral infarction volume on clinical outcome in acute stroke patients with middle cerebral artery occlusion treated by thrombolysis","volume":"48","author":"San\u00e1k","year":"2006","journal-title":"Neuroradiology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0315","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1161\/STROKEAHA.108.541656","article-title":"MRI-based selection for intra-arterial stroke therapy: value of pretreatment diffusion-weighted imaging lesion volume in selecting patients with acute stroke who will benefit from early recanalization","volume":"40","author":"Yoo","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0320","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1161\/01.STR.0000237070.80133.1d","article-title":"Tandem internal carotid artery\/middle cerebral artery occlusion: an independent predictor of poor outcome after systemic thrombolysis","volume":"37","author":"Rubiera","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0325","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.neurad.2015.07.002","article-title":"Management of minor stroke patients with proximal middle cerebral artery occlusion in the new era of thrombectomy","volume":"43","author":"Gory","year":"2016","journal-title":"J Neuroradiol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0330","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jemermed.2007.08.071","article-title":"The role of CT perfusion imaging in acute stroke diagnosis: a large single-center experience","volume":"35","author":"Rai","year":"2008","journal-title":"J Emerg Med"},{"key":"10.1016\/j.neurad.2016.10.005_bib0335","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1159\/000219300","article-title":"Perfusion CT improves diagnostic accuracy for hyperacute ischemic stroke in the 3-hour window: study of 100 patients with diffusion MRI confirmation","volume":"28","author":"Lin","year":"2009","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.neurad.2016.10.005_bib0340","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jstrokecerebrovasdis.2012.10.020","article-title":"Clinical use of computed tomographic perfusion for the diagnosis and prediction of lesion growth in acute ischemic stroke","volume":"23","author":"Huisa","year":"2014","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.1016\/j.neurad.2016.10.005_bib0345","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1161\/01.STR.28.11.2119","article-title":"Generalized efficacy of t-PA for acute stroke: subgroup analysis of the NINDS t-PA stroke trial","volume":"28","author":"Group TN t-PS.S","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0350","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1212\/01.WNL.0000071228.56362.36","article-title":"Efficacy of IV tissue plasminogen activator in acute stroke: does stroke subtype really matter?","volume":"61","author":"Hsia","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0355","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1159\/000091982","article-title":"Does thrombolysis benefit patients with lacunar syndrome?","volume":"55","author":"Cocho","year":"2006","journal-title":"Eur Neurol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0360","doi-asserted-by":"crossref","first-page":"164","DOI":"10.5853\/jos.2013.15.3.164","article-title":"Perfusion patterns of ischemic stroke on computed tomography perfusion","volume":"15","author":"Lin","year":"2013","journal-title":"J Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0365","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.nic.2011.01.008","article-title":"CT perfusion imaging in acute stroke","volume":"21","author":"Konstas","year":"2011","journal-title":"Neuroimaging Clin N Am"},{"key":"10.1016\/j.neurad.2016.10.005_bib0370","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.1161\/STROKEAHA.110.590554","article-title":"Low cerebral blood volume is predictive of diffusion restriction only in hyperacute stroke","volume":"41","author":"Knash","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0375","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1161\/01.STR.31.4.946","article-title":"Transient and permanent resolution of ischemic lesions on diffusion-weighted imaging after brief periods of focal ischemia in rats: correlation with histopathology","volume":"31","author":"Li","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0380","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1002\/1531-8249(200004)47:4<462::AID-ANA9>3.0.CO;2-Y","article-title":"Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion\/perfusion magnetic resonance imaging","volume":"47","author":"Kidwell","year":"2000","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0385","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1161\/hs0102.100884","article-title":"Severe ADC decreases do not predict irreversible tissue damage in humans","volume":"33","author":"Fiehler","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0390","first-page":"951","article-title":"Characterization and evolution of diffusion MR imaging abnormalities in stroke patients undergoing intra-arterial thrombolysis","volume":"25","author":"Schaefer","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0395","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1212\/WNL.0b013e3181f39ab6","article-title":"Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch","volume":"75","author":"Chemmanam","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.neurad.2016.10.005_bib0400","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1600-0404.1965.tb01958.x","article-title":"Normal values of regional cerebral blood flow in man, including flow and weight estimates of gray and white matter","volume":"41","author":"Ingvar","year":"2009","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.neurad.2016.10.005_bib0405","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/jnnp.2005.067363","article-title":"Perfusion CT helps decision making for thrombolysis when there is no clear time of onset","volume":"77","author":"Hellier","year":"2006","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.neurad.2016.10.005_bib0410","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1747-4949.2008.00175.x","article-title":"Perfusion CT: is it clinically useful?","volume":"3","author":"Parsons","year":"2008","journal-title":"Int J Stroke"},{"key":"10.1016\/j.neurad.2016.10.005_bib0415","first-page":"428","article-title":"Effect of training and experience on qualitative and quantitative CT perfusion data","volume":"28","author":"Sanelli","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.neurad.2016.10.005_bib0420","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1161\/STROKEAHA.107.512319","article-title":"Acue stroke imaging research roadmap","volume":"39","author":"Wintermark","year":"2008","journal-title":"Stroke"}],"container-title":["Journal of Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0150986116302115?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0150986116302115?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T10:40:54Z","timestamp":1758969654000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0150986116302115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S0150986116302115"],"URL":"https:\/\/doi.org\/10.1016\/j.neurad.2016.10.005","relation":{},"ISSN":["0150-9861"],"issn-type":[{"type":"print","value":"0150-9861"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic performance of CT cerebral blood volume colour maps for evaluation of acute infarcts; comparison with diffusion-weighted MRI within 12hours of major stroke onset","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroradiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurad.2016.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}