{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T16:49:53Z","timestamp":1768495793007,"version":"3.49.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroradiology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.neurad.2017.11.005","type":"journal-article","created":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T13:15:27Z","timestamp":1513689327000},"page":"102-107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Primary versus secondary mechanical thrombectomy for anterior circulation stroke in children: An update"],"prefix":"10.1016","volume":"45","author":[{"given":"Manuel","family":"Cappellari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Moretto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Grazioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe Kenneth","family":"Ricciardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Bovi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa Francesca Maria","family":"Ciceri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurad.2017.11.005_bib0205","first-page":"1","article-title":"Deaths: leading causes for 2010","volume":"62","author":"Heron","year":"2013","journal-title":"Natl Vital Stat Rep"},{"key":"10.1016\/j.neurad.2017.11.005_bib0210","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1177\/0883073813484358","article-title":"Long-term outcomes of pediatric ischemic stroke in adulthood","volume":"29","author":"Elbers","year":"2014","journal-title":"J Child Neurol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0215","doi-asserted-by":"crossref","first-page":"672","DOI":"10.2214\/ajr.111.4.672","article-title":"Cerebral arterial disease in children","volume":"111","author":"Harwood-Nash","year":"1971","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0220","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1111\/ijs.12604","article-title":"Intravenous thrombolysis and intra-arterial interventions in acute ischemic stroke: Italian Stroke Organisation (ISO)-SPREAD guidelines","volume":"10","author":"Toni","year":"2015","journal-title":"Int J Stroke"},{"key":"10.1016\/j.neurad.2017.11.005_bib0225","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1056\/NEJMoa1213701","article-title":"Endovascular treatment for acute ischemic stroke","volume":"368","author":"Ciccone","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neurad.2017.11.005_bib0230","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1411587","article-title":"A randomized trial of intraarterial treatment for acute ischemic stroke","volume":"372","author":"Berkhemer","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neurad.2017.11.005_bib0235","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/ijs.12424","article-title":"Endovascular treatment for small core and anterior circulation proximal occlusion with emphasis on minimizing CT to recanalization times (ESCAPE) trial: methodology","volume":"10","author":"Demchuk","year":"2015","journal-title":"Int J Stroke"},{"key":"10.1016\/j.neurad.2017.11.005_bib0240","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1056\/NEJMoa1503780","article-title":"Thrombectomy within 8hours after symptom onset in ischemic stroke","volume":"372","author":"Jovin","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neurad.2017.11.005_bib0245","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1182\/blood.V80.8.1998.1998","article-title":"Maturation of the hemostatic system during childhood","volume":"80","author":"Andrew","year":"1992","journal-title":"Blood"},{"key":"10.1016\/j.neurad.2017.11.005_bib0250","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1203\/00006450-200302000-00021","article-title":"Fibrinolytic system in adolescents: response to venous occlusion stress tests","volume":"53","author":"Monagle","year":"2003","journal-title":"Pediatr Res"},{"key":"10.1016\/j.neurad.2017.11.005_bib0255","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1046\/j.1472-8206.2003.00140.x","article-title":"Drug metabolism and disposition in children","volume":"17","author":"Strolin Benedetti","year":"2003","journal-title":"Fundam Clin Pharmacol"},{"issue":"3 Suppl.","key":"10.1016\/j.neurad.2017.11.005_bib0260","doi-asserted-by":"crossref","first-page":"645S","DOI":"10.1378\/chest.126.3_suppl.645S","article-title":"Antithrombotic therapy in children: the seventh ACCP conference on antithrombotic and thrombolytic therapy","volume":"126","author":"Monagle","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.neurad.2017.11.005_bib0265","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/S1474-4422(09)70106-1","article-title":"International Pediatric Stroke Study. Use of alteplase in childhood arterial ischaemic stroke: a multicentre, observational, cohort study","volume":"8","author":"Amlie-Lefond","year":"2009","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0270","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1161\/STROKEAHA.114.008210","article-title":"Thrombolysis in pediatric stroke study","volume":"46","author":"Rivkin","year":"2015","journal-title":"Stroke"},{"issue":"13 Suppl. 1","key":"10.1016\/j.neurad.2017.11.005_bib0275","first-page":"S158","article-title":"Endovascular therapy in children with acute ischemic stroke: review and recommendations","volume":"79","author":"Ellis","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.neurad.2017.11.005_bib0280","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1136\/neurintsurg-2016-012320","article-title":"Mechanical thrombectomy for pediatric acute ischemic stroke: review of the literature","volume":"9","author":"Satti","year":"2017","journal-title":"J Neurointerv Surg"},{"key":"10.1016\/j.neurad.2017.11.005_bib0285","first-page":"63","article-title":"New mechanical recanalization devices \u2013\u00a0the future in pediatric stroke treatment?","volume":"22","author":"Grunwald","year":"2010","journal-title":"J Invasive Cardiol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0290","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1136\/neurintsurg-2011-010108","article-title":"CT perfusion guided delayed recanalization with favorable outcome in pediatric stroke","volume":"4","author":"Xavier","year":"2012","journal-title":"J Neurointerv Surg"},{"key":"10.1016\/j.neurad.2017.11.005_bib0295","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2012-010474","article-title":"Direct thrombus aspiration using the Penumbra system for the treatment of pediatric intracranial dissection","author":"Fujimoto","year":"2012","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.neurad.2017.11.005_bib0300","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1136\/neurintsurg-2011-010100","article-title":"Mechanical embolectomy for treatment of large vessel acute ischemic stroke in children","volume":"5","author":"Tatum","year":"2013","journal-title":"J Neurointerv Surg"},{"key":"10.1016\/j.neurad.2017.11.005_bib0305","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1016\/j.athoracsur.2013.03.104","article-title":"Successful use of solitaire FR for stroke in a pediatric ventricular assist device patient","volume":"96","author":"Alnaami","year":"2013","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.neurad.2017.11.005_bib0310","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.ejpn.2014.07.006","article-title":"Experience of mechanical thrombectomy for paediatric arterial ischaemic stroke","volume":"18","author":"Bodey","year":"2014","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0315","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s00381-013-2313-3","article-title":"Modern endovascular treatments of occlusive pediatric acute ischemic strokes: case series and review of the literature","volume":"30","author":"Hu","year":"2014","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.neurad.2017.11.005_bib0320","doi-asserted-by":"crossref","first-page":"E88","DOI":"10.1111\/petr.12241","article-title":"Mechanical embolectomy for ischemic stroke in a pediatric ventricular assist device patient","volume":"18","author":"Rhee","year":"2014","journal-title":"Pediatr Transplant"},{"key":"10.1016\/j.neurad.2017.11.005_bib0325","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1177\/0883073813509889","article-title":"Acute ischemic stroke in a 12-year-old successfully treated with mechanical thrombectomy","volume":"29","author":"Sainz de la Maza","year":"2014","journal-title":"J Child Neurol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0330","doi-asserted-by":"crossref","first-page":"94","DOI":"10.5469\/neuroint.2014.9.2.94","article-title":"Successful mechanical thrombectomy in a 2-year-old male through a 4-French guide catheter","volume":"9","author":"Stidd","year":"2014","journal-title":"Neurointervention"},{"key":"10.1016\/j.neurad.2017.11.005_bib0335","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3171\/2014.10.PEDS14292","article-title":"Mechanical thrombectomy for pediatric stroke arising from an atrial myxoma: case report","volume":"15","author":"Vega","year":"2015","journal-title":"J Neurosurg Pediatr"},{"key":"10.1016\/j.neurad.2017.11.005_bib0340","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1177\/1591019916637342","article-title":"Mechanical thrombectomy in pediatric acute ischemic stroke: clinical outcomes and literature review","volume":"22","author":"Madaelil","year":"2016","journal-title":"Interv Neuroradiol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0345","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.pediatrneurol.2016.02.006","article-title":"Successful manual aspiration thrombectomy in a pediatric patient","volume":"61","author":"Weiner","year":"2016","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0350","doi-asserted-by":"crossref","first-page":"497326","DOI":"10.1155\/2010\/497326","article-title":"Hyperacute therapies for childhood stroke: a case report and review of the literature","volume":"2010","author":"Irazuzta","year":"2010","journal-title":"Neurol Res Int"},{"key":"10.1016\/j.neurad.2017.11.005_bib0355","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.pediatrneurol.2016.09.007","article-title":"Thrombectomy for acute stroke in childhood: a case report, literature review, and recommendations","volume":"66","author":"Buompadre","year":"2017","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0360","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jns.2008.07.018","article-title":"Intravenous thrombolysis followed by intra-arterial thrombolysis and mechanical thrombectomy for the treatment of pediatric ischemic stroke","volume":"275","author":"Tsivgoulis","year":"2008","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.neurad.2017.11.005_bib0365","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.pediatrneurol.2010.06.010","article-title":"Failure of a clot retrieval device in an adolescent stroke patient","volume":"43","author":"Felker","year":"2010","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0370","doi-asserted-by":"crossref","first-page":"345","DOI":"10.15274\/INR-2014-10026","article-title":"Intra-arterial treatment in a child with embolic stroke due to atrial myxoma","volume":"20","author":"van den Wijngaard","year":"2014","journal-title":"Interv Neuroradiol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0375","doi-asserted-by":"crossref","first-page":"e32","DOI":"10.1161\/STROKEAHA.114.007681","article-title":"Acute ischemic stroke in pediatric patients","volume":"46","author":"Mittal","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2017.11.005_bib0380","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1007\/s00701-016-2780-x","article-title":"Mechanical thrombectomy in cardiac myxoma stroke: a case report and review of the literature","volume":"158","author":"Chung","year":"2016","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.neurad.2017.11.005_bib0385","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1212\/WNL.54.8.1684","article-title":"Intra-arterial thrombolysis for the treatment of perioperative childhood cardioembolic stroke","volume":"54","author":"Gruber","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.neurad.2017.11.005_bib0390","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1161\/STROKEAHA.116.012619","article-title":"Outcome after thrombectomy and intravenous thrombolysis in patients with acute ischemic stroke: a prospective observational study","volume":"47","author":"Minnerup","year":"2016","journal-title":"Stroke"},{"key":"10.1016\/j.neurad.2017.11.005_bib0395","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.neurad.2017.03.001","article-title":"Neurointerventional staffing: the next frontier","volume":"44","author":"L\u00f6vblad","year":"2017","journal-title":"J Neuroradiol"},{"key":"10.1016\/j.neurad.2017.11.005_bib0400","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.neurad.2017.07.001","article-title":"New techniques in interventional neuroradiology: should we really randomize the first patient?","volume":"44","author":"Pierot","year":"2017","journal-title":"J Neuroradiol"}],"container-title":["Journal of Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0150986117302936?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0150986117302936?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T10:42:02Z","timestamp":1758969722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0150986117302936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S0150986117302936"],"URL":"https:\/\/doi.org\/10.1016\/j.neurad.2017.11.005","relation":{},"ISSN":["0150-9861"],"issn-type":[{"value":"0150-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary versus secondary mechanical thrombectomy for anterior circulation stroke in children: An update","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroradiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurad.2017.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}