{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T16:05:20Z","timestamp":1781712320552,"version":"3.54.5"},"reference-count":21,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2003,12,1]],"date-time":"2003-12-01T00:00:00Z","timestamp":1070236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2003,12,1]],"date-time":"2003-12-01T00:00:00Z","timestamp":1070236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001695","name":"Japan Science and Technology Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001695","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Research"],"published-print":{"date-parts":[[2003,12]]},"DOI":"10.1016\/j.neures.2003.08.009","type":"journal-article","created":{"date-parts":[[2003,10,27]],"date-time":"2003-10-27T21:01:58Z","timestamp":1067288518000},"page":"455-459","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Lipocalin-type prostaglandin D synthase (beta-trace) in cerebrospinal fluid: a useful marker for the diagnosis of normal pressure hydrocephalus"],"prefix":"10.1016","volume":"47","author":[{"given":"Mitsuhito","family":"Mase","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Shimazu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Seiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Oda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroya","family":"Nakau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Inui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"Eguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Urade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neures.2003.08.009_BIB1","first-page":"97","article-title":"Normal pressure hydrocephalus: neuropathological study","volume":"37","author":"Akai","year":"1987","journal-title":"Acta Pathol. Jpn."},{"key":"10.1016\/j.neures.2003.08.009_BIB2","unstructured":"American Psychiatric Association, 1994. Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), fourth ed., American Psychiatric Association, Washington, DC, pp. 133\u2013155"},{"key":"10.1016\/j.neures.2003.08.009_BIB3","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/1096-9861(20001204)428:1<62::AID-CNE6>3.0.CO;2-E","article-title":"Cellular localization of lipocalin-type prostaglandin D synthase (\u03b2-trace) in the central nervous system of the adult rats","volume":"428","author":"Beuckmann","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neures.2003.08.009_BIB4","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1148\/radiology.198.2.8596861","article-title":"Normal-pressure hydrocephalus: evaluation with cerebrospinal fluid flow measurements at MR imaging","volume":"198","author":"Bradley","year":"1996","journal-title":"Radiology"},{"key":"10.1016\/j.neures.2003.08.009_BIB5","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3181\/00379727-107-26569","article-title":"Proteins in normal cerebrospinal fluid not found in serum","volume":"107","author":"Clausen","year":"1961","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.neures.2003.08.009_BIB6","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0022-510X(65)90016-X","article-title":"The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. Observations on cerebrospinal fluid hydrodynamics","volume":"2","author":"Hakim","year":"1965","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.neures.2003.08.009_BIB7","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/j.1471-4159.1993.tb02145.x","article-title":"Purification and chemical characterization of \u03b2-trace protein from human cerebrospinal fluid: its identification as prostaglandin D synthase","volume":"61","author":"Hoffmann","year":"1993","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neures.2003.08.009_BIB8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-0404.1972.tb07527.x","article-title":"Beta-trace protein concentration in CSF in neurological disorders","volume":"48","author":"Link","year":"1972","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.neures.2003.08.009_BIB9","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1212\/WNL.47.5.1113","article-title":"Consensus guidelines for the clinical and pathological diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop","volume":"47","author":"McKeith","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.neures.2003.08.009_BIB10","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0090-6980(97)00062-2","article-title":"Prostaglandin D synthase concentration in cerebrospinal fluid and serum of patients with neurological disorders","volume":"54","author":"Melegos","year":"1997","journal-title":"Prostaglandins"},{"key":"10.1016\/j.neures.2003.08.009_BIB11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000106627","article-title":"Neuron-specific enolase, S-100 protein, myelin basic protein and lactate in CSF in dementia","volume":"8","author":"Nooijen","year":"1997","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.neures.2003.08.009_BIB12","doi-asserted-by":"crossref","first-page":"108","DOI":"10.2183\/pjab.72.108","article-title":"Quantitative sandwich enzyme-linked immunosorbent assay for human secretory prostaglandin D synthase (beta-trace)","volume":"72","author":"Oda","year":"1996","journal-title":"Proc. Jpn. Acad."},{"key":"10.1016\/j.neures.2003.08.009_BIB13","doi-asserted-by":"crossref","unstructured":"Rom\u00e1n, G.C., Tatemichi, T.K., Erkinjuntti, T., Erkinjuntti, T., Cummings, J.L., Masdeu, J.C., Garcia, J.H., Amaducci, L., Orgogozo, J.-M., Brun, A., Hofman, A., Moody, D.M., O\u2019Brien, M.D., Yamaguchi, T., Grafman, J., Drayer, B.P., Bennett, D.A., Fisher, M., Ogata, J., Kokman, E., Bermejo, F., Wolf, P.A., Gorelick, P.B., Bick, K.L., Pajeau, A.K., Bell, M.A., Decarli, C., Culebras, A., Korczyn, A.D., Bogousslavsky, J., Hartmann, A., Scheinberg, P., 1993. Vascular dementia: diagnositic criteria for research studies. Report of the Neuroepidemiology of the National Institute of Neurological Disorders and Stroke (NINDS)\u2014Association Internationale pour la Recherche et l\u2019Enseignement en Neurosciences (AIREN) International Workshop. Neurology 43, 250\u2013260.","DOI":"10.1212\/WNL.43.2.250"},{"key":"10.1016\/j.neures.2003.08.009_BIB14","first-page":"643","article-title":"Quantification of prostaglandin D synthase in cerebrospinal fluid: a potential marker for brain tumor","volume":"46","author":"Saso","year":"1998","journal-title":"Biochem. Mol. Biol. Int."},{"key":"10.1016\/j.neures.2003.08.009_BIB15","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1136\/jnnp.45.12.1130","article-title":"Assessment of damage to the central nervous system by determination of S-100 protein in cerebrospinal fluid","volume":"45","author":"Sindic","year":"1982","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neures.2003.08.009_BIB16","first-page":"25","article-title":"Classification of cerebrospinal fluid dynamics in hydrocephalus by computed tomographic cisternography","volume":"2","author":"Tamaki","year":"1980","journal-title":"Prog. Comput. Tomogr."},{"key":"10.1016\/j.neures.2003.08.009_BIB17","doi-asserted-by":"crossref","first-page":"15789","DOI":"10.1074\/jbc.272.25.15789","article-title":"Lipocalin-type prostaglandin D synthase (\u03b2-trace) is a newly recognized type of retinoid transporter","volume":"272","author":"Tanaka","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2003.08.009_BIB18","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1002\/ana.410440606","article-title":"Beta-trace protein in cerebrospinal fluid: a blood-CSF barrier-related evaluation in neurological diseases","volume":"44","author":"Tumani","year":"1998","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neures.2003.08.009_BIB19","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0304-3940(98)00021-4","article-title":"Beta-trace protein concentration in cerebrospinal fluid is decreased in patients with bacterial meningitis","volume":"242","author":"Tumani","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neures.2003.08.009_BIB20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0083-6729(00)58022-4","article-title":"Prostaglandin D synthase: structure and function","volume":"58","author":"Urade","year":"2000","journal-title":"Vitam. Horm."},{"key":"10.1016\/j.neures.2003.08.009_BIB21","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1006\/bbrc.1994.2297","article-title":"Identification of \u03b2-trace as prostaglandin D synthase","volume":"203","author":"Watanabe","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Neuroscience Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010203002682?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010203002682?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T10:17:14Z","timestamp":1759141034000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168010203002682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,12]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,12]]}},"alternative-id":["S0168010203002682"],"URL":"https:\/\/doi.org\/10.1016\/j.neures.2003.08.009","relation":{},"ISSN":["0168-0102"],"issn-type":[{"value":"0168-0102","type":"print"}],"subject":[],"published":{"date-parts":[[2003,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipocalin-type prostaglandin D synthase (beta-trace) in cerebrospinal fluid: a useful marker for the diagnosis of normal pressure hydrocephalus","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neures.2003.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.","name":"copyright","label":"Copyright"}]}}