{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:25:20Z","timestamp":1789730720326,"version":"4.0.1"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17K07078"],"award-info":[{"award-number":["17K07078"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["19K19871"],"award-info":[{"award-number":["19K19871"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20K16111"],"award-info":[{"award-number":["20K16111"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21\u2009K06394"],"award-info":[{"award-number":["21\u2009K06394"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP18K07823"],"award-info":[{"award-number":["JP18K07823"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Research"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.neures.2021.10.009","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T10:59:48Z","timestamp":1635505188000},"page":"52-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Slow progression of sciatic nerve degeneration and regeneration after loose ligation through microglial activation and decreased KCC2 levels in the mouse spinal cord ventral horn"],"prefix":"10.1016","volume":"177","author":[{"given":"Tsukasa","family":"Yafuso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Kosaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chigusa","family":"Shimizu-Okabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiko","family":"Okura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiori","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2238-1038","authenticated-orcid":false,"given":"Jeongtae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koyata","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daichi","family":"Kinjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihito","family":"Okabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5005-6710","authenticated-orcid":false,"given":"Chitoshi","family":"Takayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neures.2021.10.009_bib0005","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1272\/jnms.71.399","article-title":"[Neuropathic pain intensity depends on the degree of peripheral nerve injury in the rat]","volume":"71","author":"Abuduhadeer","year":"2004","journal-title":"J. Nippon Med. Sch."},{"key":"10.1016\/j.neures.2021.10.009_bib0010","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1460-9568.2004.03833.x","article-title":"A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses","volume":"21","author":"Adalbert","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neures.2021.10.009_bib0015","first-page":"6","article-title":"Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF\/TrkB Signaling But Is Controlled by Neuromuscular Innervation","author":"Akhter","year":"2019","journal-title":"eNeuro"},{"key":"10.1016\/j.neures.2021.10.009_bib0020","doi-asserted-by":"crossref","first-page":"857","DOI":"10.2741\/192","article-title":"Mechanisms and consequences of microglial responses to peripheral axotomy","volume":"3","author":"Aldskogius","year":"2011","journal-title":"Front Biosci. (Schol Ed)"},{"key":"10.1016\/j.neures.2021.10.009_bib0025","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.pneurobio.2012.05.005","article-title":"Specificity of peripheral nerve regeneration: interactions at the axon level","volume":"98","author":"Allodi","year":"2012","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neures.2021.10.009_bib0030","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s11064-015-1771-2","article-title":"Neuroprotective effect of natural products on peripheral nerve degeneration: a systematic review","volume":"41","author":"Araujo-Filho","year":"2016","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.neures.2021.10.009_bib0035","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0304-3959(88)90209-6","article-title":"A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man","volume":"33","author":"Bennett","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.neures.2021.10.009_bib0040","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/B978-0-444-52902-2.00019-9","article-title":"Compression and entrapment neuropathies","volume":"115","author":"Bouche","year":"2013","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.neures.2021.10.009_bib0045","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jocn.2009.03.042","article-title":"Expression of calcitonin gene-related peptide in anterior and posterior horns of the spinal cord after brachial plexus injury","volume":"17","author":"Chen","year":"2010","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.neures.2021.10.009_bib0050","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3171\/2013.8.JNS122300","article-title":"Misdirection and guidance of regenerating axons after experimental nerve injury and repair","volume":"120","author":"de Ruiter","year":"2014","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.neures.2021.10.009_bib0055","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/429815","article-title":"Microglia control neuronal network excitability via BDNF signalling","volume":"2013","author":"Ferrini","year":"2013","journal-title":"Neural Plast."},{"key":"10.1016\/j.neures.2021.10.009_bib0060","first-page":"21","article-title":"Peripheral Nerve Regeneration and Muscle Reinnervation","author":"Gordon","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neures.2021.10.009_bib0065","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00006534-199202000-00009","article-title":"Walking track analysis: a long-term assessment of peripheral nerve recovery","volume":"89","author":"Hare","year":"1992","journal-title":"Plast. Reconstr. Surg."},{"key":"10.1016\/j.neures.2021.10.009_bib0070","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0165-0173(98)00018-6","article-title":"Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB\/ATF proteins","volume":"28","author":"Herdegen","year":"1998","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.neures.2021.10.009_bib0075","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s12974-015-0332-6","article-title":"Systemic inflammation and microglial activation: systematic review of animal experiments","volume":"12","author":"Hoogland","year":"2015","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.neures.2021.10.009_bib0080","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1177\/29.4.6166661","article-title":"Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures","volume":"29","author":"Hsu","year":"1981","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.neures.2021.10.009_bib0085","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0896-6273(01)00297-5","article-title":"Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition","volume":"30","author":"Hubner","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2021.10.009_bib0090","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.aanat.2011.02.019","article-title":"Potentials and limitations of peripheral nerve injury models in rodents with particular reference to the femoral nerve","volume":"193","author":"Irintchev","year":"2011","journal-title":"Ann. Anat."},{"issue":"Suppl 1","key":"10.1016\/j.neures.2021.10.009_bib0095","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.pain.2013.06.022","article-title":"Glia and pain: is chronic pain a gliopathy?","volume":"154","author":"Ji","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.neures.2021.10.009_bib0100","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.neulet.2003.12.010","article-title":"Peripheral nerve injury evokes disabilities and sensory dysfunction in a subpopulation of rats: a closer model to human chronic neuropathic pain?","volume":"361","author":"Keay","year":"2004","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neures.2021.10.009_bib0105","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.neures.2015.09.003","article-title":"Developmental localization of calcitonin gene-related peptide in dorsal sensory axons and ventral motor neurons of mouse cervical spinal cord","volume":"105","author":"Kim","year":"2016","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.neures.2021.10.009_bib0110","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jchemneu.2017.11.002","article-title":"Changes in the expression and localization of signaling molecules in mouse facial motor neurons during regeneration of facial nerves","volume":"88","author":"Kim","year":"2018","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.neures.2021.10.009_bib0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.146718","article-title":"Development and persistence of neuropathic pain through microglial activation and KCC2 decreasing after mouse tibial nerve injury","volume":"1733","author":"Kosaka","year":"2020","journal-title":"Brain Res."},{"key":"10.1016\/j.neures.2021.10.009_bib0120","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1111\/j.1460-9568.2005.04084.x","article-title":"KCC2 expression in immature rat cortical neurons is sufficient to switch the polarity of GABA responses","volume":"21","author":"Lee","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neures.2021.10.009_bib0125","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/cne.21685","article-title":"Role of endogenous sleep-wake and analgesic systems in anesthesia","volume":"508","author":"Lu","year":"2008","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neures.2021.10.009_bib0130","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1748-1716.2006.01657.x","article-title":"The specificity of motor neurone regeneration (preferential reinnervation)","volume":"189","author":"Madison","year":"2007","journal-title":"Acta. Physiol. (Oxf)"},{"key":"10.1016\/j.neures.2021.10.009_bib0135","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1113\/JP271593","article-title":"Regulation of neuronal chloride homeostasis by neuromodulators","volume":"594","author":"Mahadevan","year":"2016","journal-title":"J Physiol"},{"key":"10.1016\/j.neures.2021.10.009_bib0140","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1002\/cne.22240","article-title":"Peripheral facial nerve axotomy in mice causes sprouting of motor axons into perineuronal central white matter: time course and molecular characterization","volume":"518","author":"Makwana","year":"2010","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neures.2021.10.009_bib0145","article-title":"An Adapted chronic constriction injury of the sciatic nerve produces sensory, affective, and cognitive impairments: a peripheral mononeuropathy model for the study of comorbid neuropsychiatric disorders associated with neuropathic pain in rats","author":"Medeiros","year":"2020","journal-title":"Pain Med."},{"key":"10.1016\/j.neures.2021.10.009_bib0150","doi-asserted-by":"crossref","first-page":"3178","DOI":"10.1016\/j.celrep.2017.03.009","article-title":"Severity of demyelinating and axonal neuropathy mouse models is modified by genes affecting structure and function of peripheral nodes","volume":"18","author":"Morelli","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.neures.2021.10.009_bib0155","doi-asserted-by":"crossref","first-page":"4412","DOI":"10.1523\/JNEUROSCI.22-11-04412.2002","article-title":"Reduction of KCC2 expression and GABAA receptor-mediated excitation after in vivo axonal injury","volume":"22","author":"Nabekura","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2021.10.009_bib0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2020.104672","article-title":"Chronic constriction injury of the sciatic nerve in rats causes different activation modes of microglia between the anterior and posterior horns of the spinal cord","volume":"134","author":"Nishihara","year":"2020","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neures.2021.10.009_bib0165","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fnana.2013.00012","article-title":"Immunolocalization of cation-chloride cotransporters in the developing and mature spinal cord of opossums, Monodelphis domestica","volume":"7","author":"Phan","year":"2013","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.neures.2021.10.009_bib0170","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.neuron.2004.06.005","article-title":"The AP-1 transcription factor c-Jun is required for efficient axonal regeneration","volume":"43","author":"Raivich","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2021.10.009_bib0175","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1083\/jcb.17.1.208","article-title":"The use of lead citrate at high pH as an electron-opaque stain in electron microscopy","volume":"17","author":"Reynolds","year":"1963","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neures.2021.10.009_bib0180","doi-asserted-by":"crossref","first-page":"3362","DOI":"10.1002\/jcp.27299","article-title":"Nerve repair and regeneration: Biological tubulization limits and future perspectives","volume":"234","author":"Riccio","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.neures.2021.10.009_bib0185","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1113\/jphysiol.2004.077495","article-title":"Two developmental switches in GABAergic signalling: the K+-Cl- cotransporter KCC2 and carbonic anhydrase CAVII","volume":"562","author":"Rivera","year":"2005","journal-title":"J Physiol"},{"key":"10.1016\/j.neures.2021.10.009_bib0190","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0169-328X(91)90027-U","article-title":"Changes in expression of peptides in rat facial motoneurons after facial nerve crushing and resection","volume":"11","author":"Saika","year":"1991","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neures.2021.10.009_bib0195","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1152\/physrev.00025.2008","article-title":"Models and mechanisms of hyperalgesia and allodynia","volume":"89","author":"Sandkuhler","year":"2009","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.neures.2021.10.009_bib0200","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jneumeth.2014.01.020","article-title":"Sciatic nerve injury: a simple and subtle model for investigating many aspects of nervous system damage and recovery","volume":"227","author":"Savastano","year":"2014","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.neures.2021.10.009_bib0205","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/WNR.0b013e32835eb867","article-title":"Salidroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats","volume":"24","author":"Sheng","year":"2013","journal-title":"Neuroreport"},{"key":"10.1016\/j.neures.2021.10.009_bib0210","series-title":"Spinal Cord Compression","author":"Singleton","year":"2020"},{"key":"10.1016\/j.neures.2021.10.009_bib0215","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0361-9230(93)90284-I","article-title":"The response of central glia to peripheral nerve injury","volume":"30","author":"Svensson","year":"1993","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.neures.2021.10.009_bib0220","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.neuroscience.2006.08.044","article-title":"Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation","volume":"143","author":"Takayama","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neures.2021.10.009_bib0225","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.brainres.2012.01.048","article-title":"GABA\/glycine signaling during degeneration and regeneration of mouse hypoglossal nerves","volume":"1446","author":"Tatetsu","year":"2012","journal-title":"Brain Res."},{"key":"10.1016\/j.neures.2021.10.009_bib0230","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1152\/jn.00721.2002","article-title":"Induction of NMDA and GABAA receptor-mediated Ca2+ oscillations with KCC2 mRNA downregulation in injured facial motoneurons","volume":"89","author":"Toyoda","year":"2003","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neures.2021.10.009_bib0235","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2560\/10\/1\/011001","article-title":"Chronic nerve root entrapment: compression and degeneration","volume":"10","author":"Vanhoestenberghe","year":"2013","journal-title":"J. Neural Eng."},{"key":"10.1016\/j.neures.2021.10.009_bib0240","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-0270(01)00378-8","article-title":"Functional evaluation of peripheral nerve regeneration in the rat: walking track analysis","volume":"108","author":"Varejao","year":"2001","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.neures.2021.10.009_bib0245","doi-asserted-by":"crossref","first-page":"491","DOI":"10.4103\/1673-5374.266068","article-title":"Animal models used to study direct peripheral nerve repair: a systematic review","volume":"15","author":"Vela","year":"2020","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.neures.2021.10.009_bib0250","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S0169-409X(03)00098-X","article-title":"Animal and cellular models of chronic pain","volume":"55","author":"Wang","year":"2003","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.neures.2021.10.009_bib0255","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.aanat.2011.04.008","article-title":"Outcome measures of peripheral nerve regeneration","volume":"193","author":"Wood","year":"2011","journal-title":"Ann. Anat."},{"key":"10.1016\/j.neures.2021.10.009_bib0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0061010","article-title":"Gamma knife irradiation of injured sciatic nerve induces histological and behavioral improvement in the rat neuropathic pain model","volume":"8","author":"Yagasaki","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neures.2021.10.009_bib0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.117959","article-title":"Resveratrol regulates the recovery of rat sciatic nerve crush injury by promoting the autophagy of Schwann cells","volume":"256","author":"Zhang","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.neures.2021.10.009_bib0270","doi-asserted-by":"crossref","DOI":"10.1016\/0960-5428(96)00017-4","article-title":"Molecular mechanisms of microglial activation","volume":"6","author":"Zielasek","year":"1996","journal-title":"Adv. Neuroimmunol."}],"container-title":["Neuroscience Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010221002170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010221002170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T10:31:25Z","timestamp":1759141885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168010221002170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":54,"alternative-id":["S0168010221002170"],"URL":"https:\/\/doi.org\/10.1016\/j.neures.2021.10.009","relation":{},"ISSN":["0168-0102"],"issn-type":[{"value":"0168-0102","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Slow progression of sciatic nerve degeneration and regeneration after loose ligation through microglial activation and decreased KCC2 levels in the mouse spinal cord ventral horn","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neures.2021.10.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. and Japan Neuroscience Society. All rights reserved.","name":"copyright","label":"Copyright"}]}}