{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:15:54Z","timestamp":1787728554731,"version":"build-2784847793"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Research"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.neures.2022.12.006","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T11:14:28Z","timestamp":1671189268000},"page":"1-12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Synapse-specific changes in Arc and BDNF in rat hippocampus following chronic temporal lobe epilepsy"],"prefix":"10.1016","volume":"191","author":[{"given":"Daniel L.","family":"Egbenya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suleman","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Chen","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne E.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svend","family":"Davanger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Pt C","key":"10.1016\/j.neures.2022.12.006_bib1","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.neuropharm.2013.04.024","article-title":"BDNF and memory processing","volume":"76","author":"Bekinschtein","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neures.2022.12.006_bib2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0306-4522(85)90299-4","article-title":"Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy","volume":"14","author":"Ben-Ari","year":"1985","journal-title":"Neuroscience"},{"key":"10.1016\/j.neures.2022.12.006_bib3","doi-asserted-by":"crossref","unstructured":"Ben-Ari, Y., 2012. Kainate and Temporal Lobe Epilepsies: 3 decades of progress. In: th, Noebels, J.L., Avoli, M., Rogawski, M.A., Olsen, R.W., Delgado-Escueta, A.V. (Eds.), Jasper's Basic Mechanisms of the Epilepsies, Bethesda (MD).","DOI":"10.1093\/med\/9780199746545.003.0033"},{"key":"10.1016\/j.neures.2022.12.006_bib4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0166-2236(00)01682-9","article-title":"BDNF and epilepsy: too much of a good thing?","volume":"24","author":"Binder","year":"2001","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib5","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/08977190410001723308","article-title":"Brain-derived neurotrophic factor","volume":"22","author":"Binder","year":"2004","journal-title":"Growth Factors"},{"key":"10.1016\/j.neures.2022.12.006_bib6","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1111\/epi.13516","article-title":"Early cardiac electrographic and molecular remodeling in a model of status epilepticus and acquired epilepsy","volume":"57","author":"Brewster","year":"2016","journal-title":"Epilepsia"},{"key":"10.1016\/j.neures.2022.12.006_bib7","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.neuron.2006.08.033","article-title":"Arc\/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking","volume":"52","author":"Chowdhury","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2022.12.006_bib8","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1523\/JNEUROSCI.17-07-02295.1997","article-title":"Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS- evidence for anterograde axonal transport","volume":"17","author":"Conner","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib9","doi-asserted-by":"crossref","first-page":"9754","DOI":"10.1523\/JNEUROSCI.22-22-09754.2002","article-title":"Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dendate granule cells in hippocampal explant cultures","volume":"22","author":"Danzer","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib10","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0144-15.2016","article-title":"Activity-regulated cytoskeleton-associated protein controls AMPAR endocytosis through a direct interaction with clathrin-adaptor protein 2","volume":"3","author":"DaSilva","year":"2016","journal-title":"eNeuro"},{"key":"10.1016\/j.neures.2022.12.006_bib11","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1083\/jcb.201201038","article-title":"BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons","volume":"196","author":"Dieni","year":"2012","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neures.2022.12.006_bib12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.mcn.2018.07.004","article-title":"Changes in synaptic AMPA receptor concentration and composition in chronic temporal lobe epilepsy","volume":"92","author":"Egbenya","year":"2018","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib13","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/j.1471-4159.2006.04087.x","article-title":"Ultrastructural localisation and differential agonist-induced regulation of AMPA and kainate receptors present at the presynaptic active zone and postsynaptic density","volume":"99","author":"Feligioni","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neures.2022.12.006_bib14","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.celrep.2017.09.045","article-title":"Arc requires PSD95 for assembly into postsynaptic complexes involved with neural dysfunction and intelligence","volume":"21","author":"Fernandez","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.neures.2022.12.006_bib15","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1212\/WNL.0000000000003509","article-title":"Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies","volume":"88","author":"Fiest","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.neures.2022.12.006_bib16","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/epi.12550","article-title":"ILAE official report: a practical clinical definition of epilepsy","volume":"55","author":"Fisher","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.neures.2022.12.006_bib17","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1177\/1073858409349903","article-title":"Proneurotrophins, seizures, and neuronal apoptosis","volume":"16","author":"Friedman","year":"2010","journal-title":"Neuroscientist"},{"key":"10.1016\/j.neures.2022.12.006_bib18","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1111\/ejn.12367","article-title":"Blocking brain-derived neurotrophic factor inhibits injury-induced hyperexcitability of hippocampal CA3 neurons","volume":"38","author":"Gill","year":"2013","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib19","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nature19766","article-title":"Autocrine BDNF-TrkB signalling within a single dendritic spine","volume":"538","author":"Harward","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.neures.2022.12.006_bib20","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.nbd.2011.01.001","article-title":"Increase in BDNF-mediated TrkB signaling promotes epileptogenesis in a mouse model of mesial temporal lobe epilepsy","volume":"42","author":"Heinrich","year":"2011","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neures.2022.12.006_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.2008.05237.x","article-title":"BDNF and the diseased nervous system: a delicate balance between adaptive and pathological processes of gene regulation","volume":"105","author":"Hu","year":"2008","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neures.2022.12.006_bib22","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0092-8674(00)81509-3","article-title":"BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex","volume":"98","author":"Huang","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.neures.2022.12.006_bib23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fnmol.2016.00010","article-title":"SNARE protein syntaxin-1 colocalizes closely with NMDA receptor subunit NR2B in postsynaptic spines in the hippocampus","volume":"9","author":"Hussain","year":"2016","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib24","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.npep.2018.09.005","article-title":"Brain-derived neurotrophic factor and epilepsy: a systematic review","volume":"72","author":"Iughetti","year":"2018","journal-title":"Neuropeptides"},{"key":"10.1016\/j.neures.2022.12.006_bib25","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1126\/science.7886457","article-title":"Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus","volume":"267","author":"Kang","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.neures.2022.12.006_bib26","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S0896-6273(00)80378-5","article-title":"Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation","volume":"19","author":"Kang","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2022.12.006_bib27","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1073\/pnas.92.1.210","article-title":"Brain-derived neurotrophic factor promotes the survival of neurons arising from the adult rat forebrain subependymal zone","volume":"92","author":"Kirschenbaum","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neures.2022.12.006_bib28","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0028-3908(98)00035-5","article-title":"A role for BDNF in the late-phase of hippocampal long-term potentiation","volume":"37","author":"Korte","year":"1998","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neures.2022.12.006_bib29","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1177\/1073858405278266","article-title":"To BDNF or not to BDNF: that is the epileptic hippocampus","volume":"11","author":"Koyama","year":"2005","journal-title":"Neuroscientist"},{"key":"10.1016\/j.neures.2022.12.006_bib30","doi-asserted-by":"crossref","first-page":"283","DOI":"10.9758\/cpn.2015.13.3.283","article-title":"Brain-derived neurotrophic factor is associated with cognitive impairment in elderly Korean individuals","volume":"13","author":"Lee","year":"2015","journal-title":"Clin. Psychopharmacol. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib31","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0306-4522(98)00035-9","article-title":"Modulation of unitary glutamatergic synapses by neurotrophin-4:5 or brain-derived neurotrophic factor in hippocampal microcultures- presynaptic enhancement depends on pre-established paired-pulse facilitation","volume":"86","author":"Lessmann","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.neures.2022.12.006_bib32","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.1016\/j.neubiorev.2013.10.011","article-title":"The kainic acid model of temporal lobe epilepsy","volume":"37","author":"Levesque","year":"2013","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.neures.2022.12.006_bib33","first-page":"490","article-title":"Neurotrophins and brain insults","volume":"17","author":"Lindvall","year":"1994","journal-title":"TINS"},{"key":"10.1016\/j.neures.2022.12.006_bib34","doi-asserted-by":"crossref","first-page":"5734","DOI":"10.1073\/pnas.92.12.5734","article-title":"Somatodendritic expression of an immediate early gene is regulated by synaptic activity","volume":"92","author":"Link","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neures.2022.12.006_bib35","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/363350a0","article-title":"Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF","volume":"363","author":"Lohof","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.neures.2022.12.006_bib36","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0079-6123(00)28020-5","article-title":"Modulation of hippocampal synaptic transmission and plasticity by neurotrophins","volume":"128","author":"Lu","year":"2000","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.neures.2022.12.006_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/0896-6273(95)90299-6","article-title":"Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites","volume":"14","author":"Lyford","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2022.12.006_bib38","doi-asserted-by":"crossref","first-page":"4424","DOI":"10.1523\/JNEUROSCI.5113-06.2007","article-title":"Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease","volume":"27","author":"Lynch","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib39","doi-asserted-by":"crossref","first-page":"13531","DOI":"10.1523\/JNEUROSCI.4576-06.2006","article-title":"Single-cell characterization of retrograde signaling by brain-derived neurotrophic factor","volume":"26","author":"Magby","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib40","series-title":"Neuroanatomical Tract-Tracing 3: Molecules, Neurons, and Systems","first-page":"72","article-title":"Postembedding immunogold cytochemistry of membrane molecules and amino acid transmitters in the central nervous system","author":"Mathiisen","year":"2006"},{"key":"10.1016\/j.neures.2022.12.006_bib41","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/(SICI)1096-9861(20000320)418:4<411::AID-CNE4>3.0.CO;2-F","article-title":"Altered mRNA expression for brain-derived neurotrophic factor and type II calcium\/calmodulin-dependent protein kinase in the hippocampus of patients with intractable temporal lobe epilepsy","volume":"418","author":"Murray","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neures.2022.12.006_bib42","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1016\/0024-3205(81)90659-7","article-title":"Minireview. Kainic acid as a tool for the study of temporal lobe epilepsy","volume":"29","author":"Nadler","year":"1981","journal-title":"Life Sci."},{"key":"10.1016\/j.neures.2022.12.006_bib43","doi-asserted-by":"crossref","first-page":"5924","DOI":"10.1523\/JNEUROSCI.4650-11.2012","article-title":"Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression","volume":"32","author":"Niere","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib44","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1073\/pnas.0409442102","article-title":"BDNF modulates GABAA receptors microtransplanted from the human epileptic brain to Xenopus oocytes","volume":"102","author":"Palma","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neures.2022.12.006_bib45","doi-asserted-by":"crossref","first-page":"18173","DOI":"10.1073\/pnas.1006546107","article-title":"Arc regulates spine morphology and maintains network stability in vivo","volume":"107","author":"Peebles","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neures.2022.12.006_bib46","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.neuron.2006.08.024","article-title":"Arc\/Arg3.1 is essential for the consolidation of synaptic plasticity and memories","volume":"52","author":"Plath","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2022.12.006_bib47","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0013-4694(72)90177-0","article-title":"Modification of seizure activity by electrical stimulation. II. Motor seizure","volume":"32","author":"Racine","year":"1972","journal-title":"Electro Clin. Neurophysiol."},{"key":"10.1016\/j.neures.2022.12.006_bib48","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1038\/nn1708","article-title":"AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc","volume":"9","author":"Rao","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib49","doi-asserted-by":"crossref","first-page":"18284","DOI":"10.3390\/ijms140918284","article-title":"Experimental models of status epilepticus and neuronal injury for evaluation of therapeutic interventions","volume":"14","author":"Reddy","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neures.2022.12.006_bib50","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.neuron.2006.09.031","article-title":"Increased expression of the immediate-early gene arc\/arg3.1 reduces AMPA receptor-mediated synaptic transmission","volume":"52","author":"Rial Verde","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2022.12.006_bib51","doi-asserted-by":"crossref","first-page":"56","DOI":"10.5698\/1535-7511-11.2.56","article-title":"Revisiting AMPA receptors as an antiepileptic drug target","volume":"11","author":"Rogawski","year":"2011","journal-title":"Epilepsy Curr. Am. Epilepsy Soc."},{"key":"10.1016\/j.neures.2022.12.006_bib52","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1006\/exnr.1997.6737","article-title":"Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective","volume":"149","author":"Rudge","year":"1998","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neures.2022.12.006_bib53","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1002\/dneu.20358","article-title":"Costorage of BDNF and neuropeptides within individual dense-core vesicles in central and peripheral neurons","volume":"67","author":"Salio","year":"2007","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.neures.2022.12.006_bib54","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.neuron.2006.08.034","article-title":"Arc\/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors","volume":"52","author":"Shepherd","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2022.12.006_bib55","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1038\/mp.2017.144","article-title":"BDNF at the synapse: why location matters","volume":"22","author":"Song","year":"2017","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neures.2022.12.006_bib56","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S1734-1140(13)71012-0","article-title":"Changes in the Egr1 and Arc expression in brain structures of pentylenetetrazole-kindled rats","volume":"65","author":"Szyndler","year":"2013","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.neures.2022.12.006_bib57","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0006-8993(98)01355-9","article-title":"Patients with temporal lobe epilepsy show an increase in brain-derived neurotrophic factor protein and its correlation with neuropeptide Y","volume":"818","author":"Takahashi","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.neures.2022.12.006_bib58","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/10172","article-title":"Different modes of expression of AMPA and NMDA receptors in hippocampal synapses","volume":"2","author":"Takumi","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib59","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0054519","article-title":"Neural progenitor cell implants modulate vascular endothelial growth factor and brain-derived neurotrophic factor expression in rat axotomized neurons","volume":"8","author":"Talaveron","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neures.2022.12.006_bib60","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1523\/JNEUROSCI.17-09-02959.1997","article-title":"Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus","volume":"17","author":"Tanaka","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib61","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.conb.2007.04.004","article-title":"Homeostatic signaling: the positive side of negative feedback","volume":"17","author":"Turrigiano","year":"2007","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.neures.2022.12.006_bib62","doi-asserted-by":"crossref","first-page":"7756","DOI":"10.1523\/JNEUROSCI.1560-06.2006","article-title":"Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins","volume":"26","author":"Volosin","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib63","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1523\/JNEUROSCI.0980-08.2009","article-title":"Development of spontaneous recurrent seizures after kainate-induced status epilepticus","volume":"29","author":"Williams","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib64","doi-asserted-by":"crossref","first-page":"7580","DOI":"10.1523\/JNEUROSCI.22-17-07580.2002","article-title":"Brain-derived neurotrophic factor promotes the maturation of GABAergic mechanisms in cultured hippocampal neurons","volume":"22","author":"Yamada","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2022.12.006_bib65","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1073\/pnas.042693699","article-title":"The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes","volume":"99","author":"Yin","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Neuroscience Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010222002978?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010222002978?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T10:33:08Z","timestamp":1759141988000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168010222002978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":65,"alternative-id":["S0168010222002978"],"URL":"https:\/\/doi.org\/10.1016\/j.neures.2022.12.006","relation":{},"ISSN":["0168-0102"],"issn-type":[{"value":"0168-0102","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synapse-specific changes in Arc and BDNF in rat hippocampus following chronic temporal lobe epilepsy","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neures.2022.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}