{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:11:18Z","timestamp":1790791878910,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019702","name":"Tokyo Metropolitan Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019702","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K02895"],"award-info":[{"award-number":["24K02895"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP24H00624"],"award-info":[{"award-number":["JP24H00624"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25K21773"],"award-info":[{"award-number":["25K21773"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K07362"],"award-info":[{"award-number":["22K07362"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K06405"],"award-info":[{"award-number":["23K06405"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP24dk0207074h000"],"award-info":[{"award-number":["JP24dk0207074h000"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Research"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.neures.2025.104960","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T06:34:37Z","timestamp":1758695677000},"page":"104960","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Animal models of tau propagation in Alzheimer's disease"],"prefix":"10.1016","volume":"220","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6760-1669","authenticated-orcid":false,"given":"Masami","family":"Masuda-Suzukake","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shotaro","family":"Shimonaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0830-9403","authenticated-orcid":false,"given":"Takashi","family":"Nonaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neures.2025.104960_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23020718","article-title":"Host tau genotype specifically designs and regulates tau seeding and spreading and host tau transformation following intrahippocampal injection of identical tau AD inoculum","volume":"23","author":"Andr\u00e9s-Benito","year":"2022","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.neures.2025.104960_bib2","doi-asserted-by":"crossref","first-page":"20309","DOI":"10.1074\/jbc.M611876200","article-title":"Fibrillogenic nuclei composed of P301L mutant tau induce elongation of P301L tau but not wild-type tau","volume":"282","author":"Aoyagi","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2025.104960_bib3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.cell.2020.01.027","article-title":"Posttranslational modifications mediate the structural diversity of tauopathy strains","volume":"180","author":"Arakhamia","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.neures.2025.104960_bib4","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1212\/WNL.42.3.631","article-title":"Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease","volume":"42","author":"Arriagada","year":"1992","journal-title":"Neurology"},{"key":"10.1016\/j.neures.2025.104960_bib5","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1016\/j.ajpath.2016.06.008","article-title":"High-molecular-weight paired helical filaments from Alzheimer brain induces seeding of wild-type mouse tau into an argyrophilic 4R tau pathology in Vivo","volume":"186","author":"Audouard","year":"2016","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.neures.2025.104960_bib6","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20192193","article-title":"\u03b1-Synuclein modulates tau spreading in mouse brains","volume":"218","author":"Bassil","year":"2021","journal-title":"J. Exp. Med"},{"key":"10.1016\/j.neures.2025.104960_bib7","doi-asserted-by":"crossref","first-page":"9034","DOI":"10.1073\/pnas.1530287100","article-title":"Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure","volume":"100","author":"Berriman","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neures.2025.104960_bib8","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neures.2025.104960_bib9","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/ncb1901","article-title":"Transmission and spreading of tauopathy in transgenic mouse brain","volume":"11","author":"Clavaguera","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.neures.2025.104960_bib10","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/2051-5960-1-54","article-title":"Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain","volume":"1","author":"Dan","year":"2013","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.neures.2025.104960_bib11","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1002\/alz.13604","article-title":"Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Abeta mediates pathology maturation","volume":"20","author":"Darricau","year":"2024","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.neures.2025.104960_bib12","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1007\/s00401-018-1914-z","article-title":"Tau filaments from multiple cases of sporadic and inherited alzheimer's disease adopt a common fold","volume":"136","author":"Falcon","year":"2018","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neures.2025.104960_bib13","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3389\/fnagi.2019.00112","article-title":"Involvement of oligodendrocytes in tau seeding and spreading in tauopathies","volume":"11","author":"Ferrer","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.neures.2025.104960_bib14","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nature23002","article-title":"Cryo-EM structures of tau filaments from alzheimer's disease","volume":"547","author":"Fitzpatrick","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.neures.2025.104960_bib15","doi-asserted-by":"crossref","first-page":"15712","DOI":"10.1073\/pnas.95.26.15712","article-title":"A nucleated assembly mechanism of alzheimer paired helical filaments","volume":"95","author":"Friedhoff","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neures.2025.104960_bib16","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1002\/cne.25490","article-title":"Expression of tau and phosphorylated tau in the brain of normal and hemiparkinsonian rhesus macaques","volume":"531","author":"Gambardella","year":"2023","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neures.2025.104960_bib17","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/s40478-019-0771-x","article-title":"Encephalopathy induced by alzheimer brain inoculation in a non-human primate","volume":"7","author":"Gary","year":"2019","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.neures.2025.104960_bib18","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1212\/01.WNL.0000063311.58879.01","article-title":"Tangle and neuron numbers, but not amyloid load, predict cognitive status in alzheimer's disease","volume":"60","author":"Giannakopoulos","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.neures.2025.104960_bib19","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1042\/EBC20210025","article-title":"Cryo-EM structures of tau filaments from human brain","volume":"65","author":"Goedert","year":"2021","journal-title":"Essays Biochem"},{"key":"10.1016\/j.neures.2025.104960_bib20","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/0896-6273(89)90210-9","article-title":"Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of alzheimer's disease","volume":"3","author":"Goedert","year":"1989","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2025.104960_bib21","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/S0896-6273(00)80615-7","article-title":"Tau mutations cause frontotemporal dementias","volume":"21","author":"Goedert","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2025.104960_bib22","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/brain\/aww230","article-title":"Like prions: the propagation of aggregated tau and alpha-synuclein in neurodegeneration","volume":"140","author":"Goedert","year":"2017","journal-title":"Brain"},{"key":"10.1016\/j.neures.2025.104960_bib23","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1126\/science.1062097","article-title":"Formation of neurofibrillary tangles in P301l tau transgenic mice induced by abeta 42 fibrils","volume":"293","author":"Gotz","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.neures.2025.104960_bib24","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/1471-2202-14-148","article-title":"Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging","volume":"14","author":"Gumucio","year":"2013","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.neures.2025.104960_bib25","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1084\/jem.20160833","article-title":"Unique pathological tau conformers from alzheimer's brains transmit tau pathology in nontransgenic mice","volume":"213","author":"Guo","year":"2016","journal-title":"J. Exp. Med"},{"key":"10.1016\/j.neures.2025.104960_bib26","doi-asserted-by":"crossref","first-page":"17047","DOI":"10.1016\/S0021-9258(18)41890-X","article-title":"Protein sequence and mass spectrometric analyses of tau in the alzheimer's disease brain","volume":"267","author":"Hasegawa","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2025.104960_bib27","doi-asserted-by":"crossref","first-page":"33118","DOI":"10.1074\/jbc.272.52.33118","article-title":"Alzheimer-like changes in microtubule-associated protein tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation","volume":"272","author":"Hasegawa","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2025.104960_bib28","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1038\/s41467-019-10278-x","article-title":"Tau binding protein CAPON induces tau aggregation and neurodegeneration","volume":"10","author":"Hashimoto","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neures.2025.104960_bib29","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/s41467-019-13787-x","article-title":"Transmission of tauopathy strains is independent of their isoform composition","volume":"11","author":"He","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neures.2025.104960_bib30","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.gene.2004.07.013","article-title":"Tau gene (MAPT) sequence variation among primates","volume":"341","author":"Holzer","year":"2004","journal-title":"Gene"},{"key":"10.1016\/j.neures.2025.104960_bib31","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1126\/science.282.5395.1914","article-title":"Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17","volume":"282","author":"Hong","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.neures.2025.104960_bib32","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/brain\/awab289","article-title":"Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms","volume":"145","author":"Hosokawa","year":"2022","journal-title":"Brain"},{"key":"10.1016\/j.neures.2025.104960_bib33","doi-asserted-by":"crossref","DOI":"10.1002\/alz.14366","article-title":"Marmosets as model systems for the study of alzheimer's disease and related dementias: substantiation of physiological tau 3R and 4R isoform expression and phosphorylation","volume":"21","author":"Huhe","year":"2025","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.neures.2025.104960_bib34","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1093\/brain\/aws013","article-title":"Acetylated tau, a novel pathological signature in alzheimer's disease and other tauopathies","volume":"135","author":"Irwin","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.neures.2025.104960_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2020.581936","article-title":"Comparison of common and disease-specific post-translational modifications of pathological tau associated with a wide range of tauopathies","volume":"14","author":"Kametani","year":"2020","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.neures.2025.104960_bib36","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40478-021-01127-4","article-title":"Alzheimer's disease brain contains tau fractions with differential prion-like activities","volume":"9","author":"Li","year":"2021","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.neures.2025.104960_bib37","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.76494","article-title":"Assembly of recombinant tau into filaments identical to those of alzheimer's disease and chronic traumatic encephalopathy","volume":"11","author":"Lovestam","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.neures.2025.104960_bib38","doi-asserted-by":"crossref","first-page":"fcaa091","DOI":"10.1093\/braincomms\/fcaa091","article-title":"Dextran sulphate-induced tau assemblies cause endogenous tau aggregation and propagation in wild-type mice","volume":"2","author":"Masuda-Suzukake","year":"2020","journal-title":"Brain Commun."},{"key":"10.1016\/j.neures.2025.104960_bib39","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/0896-6273(93)90063-W","article-title":"Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments","volume":"10","author":"Morishima-Kawashima","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2025.104960_bib40","doi-asserted-by":"crossref","first-page":"11406","DOI":"10.1523\/JNEUROSCI.1230-17.2017","article-title":"Pathological tau strains from human brains recapitulate the diversity of tauopathies in nontransgenic mouse brain","volume":"37","author":"Narasimhan","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neures.2025.104960_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.101159","article-title":"Spreading of alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-\u03b2","volume":"297","author":"Nies","year":"2021","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2025.104960_bib42","doi-asserted-by":"crossref","first-page":"34885","DOI":"10.1074\/jbc.M110.148460","article-title":"Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases","volume":"285","author":"Nonaka","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2025.104960_bib43","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.neurobiolaging.2010.09.009","article-title":"Age-related cerebral atrophy in nonhuman primates predicts cognitive impairments","volume":"33","author":"Picq","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neures.2025.104960_bib44","doi-asserted-by":"crossref","first-page":"12754","DOI":"10.1074\/jbc.RA119.009487","article-title":"Humanization of the entire murine mapt gene provides a murine model of pathological human tau propagation","volume":"294","author":"Saito","year":"2019","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2025.104960_bib45","doi-asserted-by":"crossref","first-page":"11433","DOI":"10.1074\/jbc.RA119.008415","article-title":"Tau isoform expression and phosphorylation in marmoset brains","volume":"294","author":"Sharma","year":"2019","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neures.2025.104960_bib46","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0165-3806(03)00056-7","article-title":"Isoforms changes of tau protein during development in various species","volume":"142","author":"Takuma","year":"2003","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.neures.2025.104960_bib47","doi-asserted-by":"crossref","first-page":"4988","DOI":"10.1093\/brain\/awad272","article-title":"Distinct tau folds initiate templated seeding and alter the post-translational modification profile","volume":"146","author":"Tarutani","year":"2023","journal-title":"Brain"},{"key":"10.1016\/j.neures.2025.104960_bib48","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1212\/WNL.58.12.1791","article-title":"Phases of a beta-deposition in the human brain and its relevance for the development of AD","volume":"58","author":"Thal","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.neures.2025.104960_bib49","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/s43587-022-00204-0","article-title":"Biomarker modeling of alzheimer's disease using PET-based braak staging","volume":"2","author":"Therriault","year":"2022","journal-title":"Nat. Aging"},{"key":"10.1016\/j.neures.2025.104960_bib50","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ajpath.2013.03.015","article-title":"Neurodegenerative disorder FTDP-17-related tau intron 10 +16C --> t mutation increases tau exon 10 splicing and causes tauopathy in transgenic mice","volume":"183","author":"Umeda","year":"2013","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.neures.2025.104960_bib51","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00401-015-1525-x","article-title":"Heterotypic seeding of tau fibrillization by pre-aggregated abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo","volume":"131","author":"Vasconcelos","year":"2016","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neures.2025.104960_bib52","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s00401-018-1953-5","article-title":"Amyloid-beta pathology enhances pathological fibrillary tau seeding induced by alzheimer PHF in vivo","volume":"137","author":"Vergara","year":"2019","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neures.2025.104960_bib53","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/j.cell.2020.10.029","article-title":"Tau PTM profiles identify patient heterogeneity and stages of alzheimer's disease","volume":"183","author":"Wesseling","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.neures.2025.104960_bib54","article-title":"Heparin-induced tau filaments are polymorphic and differ from those in alzheimer's and pick's diseases","volume":"8","author":"Zhang","year":"2019","journal-title":"Elife"}],"container-title":["Neuroscience Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010225001439?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010225001439?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:52:10Z","timestamp":1773129130000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168010225001439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":54,"alternative-id":["S0168010225001439"],"URL":"https:\/\/doi.org\/10.1016\/j.neures.2025.104960","relation":{},"ISSN":["0168-0102"],"issn-type":[{"value":"0168-0102","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Animal models of tau propagation in Alzheimer's disease","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neures.2025.104960","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104960"}}