{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:32:01Z","timestamp":1793147521833,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Research"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.neures.2026.105140","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:16:47Z","timestamp":1792718207000},"page":"105140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Brain volume analysis-guided basic research in psychiatry"],"prefix":"10.1016","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2511-0057","authenticated-orcid":false,"given":"Kenji F.","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshifumi","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neures.2026.105140_bib1","article-title":"Distinct classes of antidepressants commonly act to shape pallidal structure and function in mice","author":"Abe","year":"2023","journal-title":"bioRxiv"},{"key":"10.1016\/j.neures.2026.105140_bib2","article-title":"Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia","volume":"4","author":"Abe","year":"2023","journal-title":"Cell. Rep. Med."},{"key":"10.1016\/j.neures.2026.105140_bib3","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1038\/s41386-023-01791-1","article-title":"Neurogenesis-independent mechanisms of MRI-detectable hippocampal volume increase following electroconvulsive stimulation","volume":"49","author":"Abe","year":"2024","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neures.2026.105140_bib4","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.biopsych.2011.05.017","article-title":"Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia","volume":"70","author":"Andreasen","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib5","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1002\/mds.26528","article-title":"Effect of levodopa-carbidopa intestinal gel on dyskinesia in advanced Parkinson's disease patients","volume":"31","author":"Antonini","year":"2016","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neures.2026.105140_bib6","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1006\/nimg.2000.0582","article-title":"Voxel-based morphometry--the methods","volume":"11","author":"Ashburner","year":"2000","journal-title":"Neuroimage"},{"key":"10.1016\/j.neures.2026.105140_bib7","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/427311a","article-title":"Changes in grey matter induced by training","volume":"427","author":"Draganski","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.neures.2026.105140_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jmri.23671","article-title":"Clinical use of brain volumetry","volume":"37","author":"Giorgio","year":"2013","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.neures.2026.105140_bib9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/archpsyc.57.1.65","article-title":"Decreased Dendritic Spine Density on Prefrontal Cortical Pyramidal Neurons in Schizophrenia","volume":"57","author":"Glantz","year":"2000","journal-title":"Arch. General. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib10","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/nrn2699","article-title":"Experience-dependent structural synaptic plasticity in the mammalian brain","volume":"10","author":"Holtmaat","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neures.2026.105140_bib11","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S0140-6736(76)90890-4","article-title":"Cerebral ventricular size and cognitive impairment in chronic schizophrenia","volume":"308","author":"Johnstone","year":"1976","journal-title":"Lancet"},{"key":"10.1016\/j.neures.2026.105140_bib12","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.ccell.2020.03.008","article-title":"Advancing cancer research and medicine with single-cell genomics","volume":"37","author":"Lim","year":"2020","journal-title":"Cancer Cell."},{"key":"10.1016\/j.neures.2026.105140_bib13","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jad.2019.05.048","article-title":"Basal ganglia volumetric changes in psychotic spectrum disorders","volume":"255","author":"Liu","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neures.2026.105140_bib14","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/nature06976","article-title":"What we can do and what we cannot do with fMRI","volume":"453","author":"Logothetis","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.neures.2026.105140_bib15","series-title":"Proceedings of the 2026 ISMRM-ISMRT Annual Meeting and Exhibition","first-page":"331","article-title":"VBM reveals that electroconvulsive therapy increases brain volume linked with synaptic structural changes in depressive mice","author":"Merante","year":"2026"},{"key":"10.1016\/j.neures.2026.105140_bib16","doi-asserted-by":"crossref","DOI":"10.1007\/s12565-025-00862-1","article-title":"Combination method of macroscopic imaging with MRI and microscopic imaging with super resolution microscopy for brain microstructure analysis","author":"Nakano","year":"2025","journal-title":"Anat. Sci. Int."},{"key":"10.1016\/j.neures.2026.105140_bib17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.neuroscience.2003.08.010","article-title":"Normalization of glutamate decarboxylase gene expression in the entopeduncular nucleus of rats with a unilateral 6-hydroxydopamine lesion correlates with increased GABAergic input following intermittent but not continuous levodopa","volume":"123","author":"Nielsen","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.neures.2026.105140_bib18","doi-asserted-by":"crossref","first-page":"5206","DOI":"10.1038\/s41380-023-02141-9","article-title":"Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification","volume":"28","author":"Okada","year":"2023","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib19","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1038\/mp.2015.209","article-title":"Abnormal asymmetries in subcortical brain volume in schizophrenia","volume":"21","author":"Okada","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib20","doi-asserted-by":"crossref","DOI":"10.1038\/s41380-026-03729-7","article-title":"The role of the globus pallidus subregions in the schizophrenia spectrum continuum","author":"Okada","year":"2026","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib21","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/s41591-025-04086-8","article-title":"Real-world clinical utility of comprehensive genomic profiling in advanced solid tumors","volume":"32","author":"Saito","year":"2026","journal-title":"Nat. Med."},{"key":"10.1016\/j.neures.2026.105140_bib22","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1176\/ajp.151.6.842","article-title":"Decreased regional cortical gray matter volume in schizophrenia","volume":"151","author":"Schlaepfer","year":"1994","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib23","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1038\/nn.2412","article-title":"Training induces changes in white-matter architecture","volume":"12","author":"Scholz","year":"2009","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neures.2026.105140_bib24","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/s41592-019-0551-3","article-title":"Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging","volume":"16","author":"Shariatgorji","year":"2019","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neures.2026.105140_bib25","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1056\/NEJM199208273270905","article-title":"Abnormalities of the Left Temporal Lobe and Thought Disorder in Schizophrenia","volume":"327","author":"Shenton","year":"1992","journal-title":"New. Engl. J. Med."},{"key":"10.1016\/j.neures.2026.105140_bib26","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1192\/bjp.2017.11","article-title":"Effect of electroconvulsive therapy on hippocampal and amygdala volumes: systematic review and meta-analysis","volume":"212","author":"Takamiya","year":"2018","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2024.111022","article-title":"Striatum and globus pallidus structural abnormalities in schizophrenia: A retrospective study of the different stages of the disease","volume":"133","author":"Tang","year":"2024","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib28","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1440-1789.2004.00559.x","article-title":"Hypertrophy of medial globus pallidus and substantia nigra reticulata in 6-hydroxydopaminelesioned rats treated with L-DOPA: implication for L-DOPA-induced dyskinesia in Parkinson\u2019s disease","volume":"24","author":"Tomiyama","year":"2004","journal-title":"Neuropathology"},{"key":"10.1016\/j.neures.2026.105140_bib29","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0149-7634(02)00008-8","article-title":"The vacuous chewing movement (VCM) model of tardive dyskinesia revisited: is there a relationship to dopamine D(2) receptor occupancy?","volume":"26","author":"Turrone","year":"2002","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neures.2026.105140_bib30","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.neuron.2020.03.004","article-title":"Whole-brain profiling of cells and circuits in mammals by tissue clearing and light-sheet microscopy","volume":"106","author":"Ueda","year":"2020","journal-title":"Neuron"},{"key":"10.1016\/j.neures.2026.105140_bib31","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/mp.2015.63","article-title":"Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium","volume":"21","author":"Van Erp","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib32","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.biopsych.2018.04.023","article-title":"Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the enhancing neuro imaging genetics through meta analysis (ENIGMA) consortium","volume":"84","author":"Van Erp","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib33","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.biopsych.2007.01.004","article-title":"Progressive brain volume loss in schizophrenia over the course of the illness: evidence of maturational abnormalities in early adulthood","volume":"63","author":"Van Haren","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neures.2026.105140_bib34","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1176\/ajp.157.1.16","article-title":"Meta-analysis of regional brain volumes in schizophrenia","volume":"157","author":"Wright","year":"2000","journal-title":"Am. J. Psychiatry"}],"container-title":["Neuroscience Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010226001276?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168010226001276?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:32:20Z","timestamp":1793143940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168010226001276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":34,"alternative-id":["S0168010226001276"],"URL":"https:\/\/doi.org\/10.1016\/j.neures.2026.105140","relation":{},"ISSN":["0168-0102"],"issn-type":[{"value":"0168-0102","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brain volume analysis-guided basic research in psychiatry","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neures.2026.105140","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105140"}}