{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:22:52Z","timestamp":1765887772492},"reference-count":102,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Yannick Fortin PhD"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroToxicology"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.neuro.2016.03.008","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T12:45:57Z","timestamp":1458391557000},"page":"20-31","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["A systematic review of the risks factors associated with the onset and natural progression of spina bifida"],"prefix":"10.1016","volume":"61","author":[{"given":"Jennifer","family":"Donnan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey","family":"Sikora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Morrissey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kayla","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuro.2016.03.008_bib0005","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1097\/EDE.0b013e3182227887","article-title":"Folic acid intake and spina bifida in the era of dietary folic acid fortification","volume":"22","author":"Ahrens","year":"2011","journal-title":"Epidemiology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0010","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1136\/pmj.78.915.23","article-title":"Inflammatory bowel disease in pregnancy","volume":"78","author":"Alstead","year":"2002","journal-title":"Postgrad. Med. J."},{"key":"10.1016\/j.neuro.2016.03.008_bib0015","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1093\/ije\/dyi234","article-title":"Congenital structural anomalies in offspring of women with epilepsy\u2014a population-based cohort study in Finland","volume":"35","author":"Artama","year":"2006","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0020","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/ddrr.93","article-title":"Epidemiologic and genetic aspects of spina bifida and other neural tube defects","volume":"16","author":"Au","year":"2010","journal-title":"Dev. Dis. Res. Rev."},{"key":"10.1016\/j.neuro.2016.03.008_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.85.1.1","article-title":"Diabetes mellitus during pregnancy and the risks for specific birth defects: a population-based case-control study","volume":"85","author":"Becerra","year":"1990","journal-title":"Pediatrics"},{"key":"10.1016\/j.neuro.2016.03.008_bib0030","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF00162315","article-title":"Maternal epilepsy and birth defects: a case-control study in the italian multicentric registry of birth defects (IPIMC)","volume":"1","author":"Bertollini","year":"1985","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0035","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/s00404-010-1762-0","article-title":"Seasonality of spina bifida in northern Germany","volume":"284","author":"Beyer","year":"2011","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.neuro.2016.03.008_bib0040","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1136\/oem.59.2.92","article-title":"Risk of birth defects by parental occupational exposure to 50 Hz electromagnetic fields: a population based study","volume":"59","author":"Blaasaas","year":"2002","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0045","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/bdra.20651","article-title":"Effect of maternal asthma on the risk of specific congenital malformations: a population-based cohort study","volume":"88","author":"Blais","year":"2010","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0050","doi-asserted-by":"crossref","first-page":"433","DOI":"10.5271\/sjweh.164","article-title":"Spina bifida and parental occupation in a Swedish register-based study","volume":"22","author":"Blatter","year":"1996","journal-title":"Scand. J. Work Environ. Health"},{"key":"10.1016\/j.neuro.2016.03.008_bib0055","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1136\/oem.53.2.80","article-title":"Maternal occupational exposure during pregnancy and the risk of spina bifida","volume":"53","author":"Blatter","year":"1996","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0060","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1097\/00001648-199603000-00014","article-title":"Spina bifida and parental occupation","volume":"7","author":"Blatter","year":"1996","journal-title":"Epidemiology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0065","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/(SICI)1097-0274(199709)32:3<283::AID-AJIM15>3.0.CO;2-R","article-title":"Paternal occupational exposure around conception and spina bifida in offspring","volume":"32","author":"Blatter","year":"1997","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0070","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1093\/oxfordjournals.aje.a010290","article-title":"5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review","volume":"151","author":"Botto","year":"2000","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0075","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1136\/adc.66.10.1223","article-title":"Neural tube defects, maternal cohorts, age: a pointer to aetiology","volume":"66","author":"Bound","year":"1991","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.neuro.2016.03.008_bib0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1136\/adc.76.2.107","article-title":"Involvement of deprivation and environmental lead in neural tube defects: a matched case-control study","volume":"76","author":"Bound","year":"1997","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.neuro.2016.03.008_bib0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2010.12.039","article-title":"Maternal treatment with opioid analgesics and risk for birth defects","volume":"204","author":"Broussard","year":"2011","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0090","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/oxfordjournals.aje.a008653","article-title":"Hispanic origin and neural tube defects in Houston\/Harris county, Texas. II. Risk factors","volume":"143","author":"Canfield","year":"1996","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0095","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1002\/bdra.20294","article-title":"National estimates and race\/ethnic-specific variation of selected birth defects in the United States, 1999\u20132001","volume":"76","author":"Canfield","year":"2006","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0100","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0306-9877(02)00402-4","article-title":"Diet quality and risk of neural tube defects","volume":"60","author":"Carmichael","year":"2003","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.neuro.2016.03.008_bib0105","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/01.ede.0000259986.85239.87","article-title":"Maternal stressful life events and risks of birth defects","volume":"18","author":"Carmichael","year":"2007","journal-title":"Epidemiology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0110","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1002\/bdra.20517","article-title":"Markers of acculturation and risk of NTDs among hispanic women in California","volume":"82","author":"Carmichael","year":"2008","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0115","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/bdra.20675","article-title":"Periconceptional nutrient intakes and risks of neural tube defects in california","volume":"88","author":"Carmichael","year":"2010","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0120","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1001\/archpediatrics.2011.185","article-title":"Reduced risks of neural tube defects and orofacial clefts with higher diet quality","volume":"166","author":"Carmichael","year":"2012","journal-title":"Arch. Pediatr. Adolesc. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2007.08.044","article-title":"Antifungal drugs and the risk of selected birth defects","volume":"198","author":"Carter","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0130","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/(SICI)1096-8628(19990903)86:1<9::AID-AJMG3>3.0.CO;2-X","article-title":"Altitude as a risk factor for congenital anomalies","volume":"86","author":"Castilla","year":"1999","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.neuro.2016.03.008_bib0135","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1093\/humrep\/dem043","article-title":"Teenage pregnancy and congenital anomalies: which system is vulnerable?","volume":"22","author":"Chen","year":"2007","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.neuro.2016.03.008_bib0140","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1007\/s00381-011-1473-2","article-title":"Decreased incidence of myelomeningocele at birth: effect of folic acid recommendations or prenatal diagnostics?","volume":"11","author":"Clemmensen","year":"2011","journal-title":"Childs Nerv. Syst."},{"key":"10.1016\/j.neuro.2016.03.008_bib0145","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1002\/ajmg.a.35430","article-title":"Wheat flour fortification with folic acid: changes in neural tube defects rates in chile","volume":"158A","author":"Cortes","year":"2012","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.neuro.2016.03.008_bib0150","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1093\/aje\/153.4.325","article-title":"Maternal exposure to nitrate from drinking water and diet and risk for neural tube defects","volume":"153","author":"Croen","year":"2001","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0155","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/s00381-010-1372-y","article-title":"Maternal periconceptional factors affect the risk of spina bifida-affected pregnancies: an italian case-control study","volume":"27","author":"De Marco","year":"2011","journal-title":"Child Nerv. Syst."},{"key":"10.1016\/j.neuro.2016.03.008_bib0160","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1002\/bdra.20485","article-title":"Spina bifida before and after folic acid fortification in Canada","volume":"82","author":"De Wals","year":"2008","journal-title":"B irth Defects Res A Clin Mol Teratol ."},{"key":"10.1016\/j.neuro.2016.03.008_bib0165","first-page":"CD007950","article-title":"Effects and safety of periconceptional folate supplementation for preventing birth defects","author":"De-Regil","year":"2010","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.neuro.2016.03.008_bib0170","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1136\/oemed-2011-100245","article-title":"Maternal occupational exposure to organic solvents during early pregnancy and risks of neural tube defects and orofacial clefts","volume":"69","author":"Desrosiers","year":"2012","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0175","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1093\/oxfordjournals.aje.a116394","article-title":"Congenital defects and electric bed heating in new york state: a register-based case-control study","volume":"135","author":"Dlugosz","year":"1992","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0180","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/bdra.20831","article-title":"Maternal use of hot tub and major structural birth defects","volume":"91","author":"Duong","year":"2011","journal-title":"Birth Defects Res. A Clin. Mol. Terratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0185","series-title":"Epidemiology and Control of Neural Tube Defects","author":"Elwood","year":"1992"},{"key":"10.1016\/j.neuro.2016.03.008_bib0190","first-page":"9","article-title":"677C>T and 1298A>C polymorphisms of methylenetetrahydropholate reductase gene and biochemical parameters in turkish population with spina bifida occulta","volume":"20","author":"Eser","year":"2010","journal-title":"Turk. Neurosurg."},{"key":"10.1016\/j.neuro.2016.03.008_bib0195","doi-asserted-by":"crossref","first-page":"R113","DOI":"10.1093\/hmg\/ddp347","article-title":"Genetics of human neural tube defects","volume":"18","author":"Greene","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neuro.2016.03.008_bib0200","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/S0002-9378(03)00807-X","article-title":"Maternal myo-inositol, glucose, zinc status is associated with the risk of offspring with spina bifida","volume":"189","author":"Groenen","year":"2003","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0205","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ajog.2003.12.032","article-title":"Marginal maternal vitamin B12 status increases the risk of offspring with spina bifida","volume":"191","author":"Groenen","year":"2004","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0210","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1067\/j.cpradiol.2012.06.002","article-title":"Congenital spinal cord anomalies: a pictorial review","volume":"42","author":"Gupta","year":"2013","journal-title":"Curr. Probl. Diagn. Radiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0215","series-title":"Congenital Anomalies in Canada: a Perinatal Health Report","author":"Health Canada","year":"2002"},{"key":"10.1016\/j.neuro.2016.03.008_bib0220","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1093\/aje\/153.10.961","article-title":"Neural tube defects in relation to use of folic acid antagonists during pregnancy","volume":"153","author":"Hernandez-Diaz","year":"2001","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0225","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.neuro.2016.06.017","article-title":"Systematic reviews of factors associated with the onset and progression of neurological conditions in humans: a methodological overview","volume":"61","author":"Hersi","year":"2017","journal-title":"NeuroToxicology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0230","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1002\/pds.1975","article-title":"Does folic acid use decrease the risk for spina bifida after in utero exposure to valproic acid?","volume":"19","author":"Jentink","year":"2010","journal-title":"Pharmacoepidemiol. Drug Saf."},{"key":"10.1016\/j.neuro.2016.03.008_bib0235","doi-asserted-by":"crossref","first-page":"c6581","DOI":"10.1136\/bmj.c6581","article-title":"Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study","volume":"341","author":"Jentink","year":"2010","journal-title":"Br. Med. J."},{"key":"10.1016\/j.neuro.2016.03.008_bib0240","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1056\/NEJMoa0907328","article-title":"Valproic acid monotherapy in pregnancy and major congenital malformations","volume":"362","author":"Jentink","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0245","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/ajmg.a.20505","article-title":"New 19bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): a risk factor for spina bifida acting in mothers during pregnancy?","volume":"124A","author":"Johnson","year":"2004","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.neuro.2016.03.008_bib0250","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1093\/oxfordjournals.aje.a009408","article-title":"Maternal smoking, body mass index, neural tube defects","volume":"147","author":"Kallen","year":"1998","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0255","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/tera.1420210114","article-title":"Maternal fever and neural tube defects","volume":"21","author":"Layde","year":"1980","journal-title":"Teratology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0260","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1365-3016.2006.00694.x","article-title":"A population-based case-control study of risk factors for neural tube defects in four high-prevalence areas of Shanxi province","volume":"20","author":"Li","year":"2006","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0265","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.neuro.2016.09.018","article-title":"Genetic variation associated with the occurrence and progression of neurological disorders","volume":"61","author":"Little","year":"2017","journal-title":"Neurotoxicolgy"},{"key":"10.1016\/j.neuro.2016.03.008_bib0270","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/ajim.20102","article-title":"Paternal organic solvent exposure and adverse pregnancy outcomes: a meta-analysis","volume":"47","author":"Logman","year":"2005","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0275","first-page":"431","article-title":"Previous abortion and the risk of neural tube defects: a case-control study","volume":"56","author":"Lu","year":"2011","journal-title":"J. Reprod. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0280","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1056\/NEJM199103073241004","article-title":"Cesarean section before the onset of labor and subsequent motor function in infants with meningomyelocele diagnosed antenatally","volume":"324","author":"Luthy","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0285","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/oxfordjournals.aje.a117243","article-title":"Maternal flu, fever, the risk of neural tube defects: a population- based case-control study","volume":"140","author":"Lynberg","year":"1994","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0290","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0890-6238(01)00199-X","article-title":"The teratogenic effect of carbamazepine: a meta-analysis of 1255 exposures","volume":"16","author":"Matalon","year":"2002","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0295","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/ajim.4700240103","article-title":"Case-control study of congenital defects and parental employment in health care","volume":"24","author":"Matte","year":"1993","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0300","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1159\/000064629","article-title":"Prevention and detection of diabetic embryopathy","volume":"5","author":"McLeod","year":"2002","journal-title":"Community Genet."},{"key":"10.1016\/j.neuro.2016.03.008_bib0305","first-page":"98","article-title":"Ineffectiveness of dietary folic acid supplementation on the incidence of lipomyelomeningocele: pathogenetic implications","volume":"100","author":"McNeely","year":"2004","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.neuro.2016.03.008_bib0310","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1001\/jama.1992.03490070064043","article-title":"Maternal heat exposure and neural tube defects","volume":"268","author":"Milunsky","year":"1992","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.neuro.2016.03.008_bib0315","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1016\/S0140-6736(04)17445-X","article-title":"Spina bifida","volume":"364","author":"Mitchell","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.neuro.2016.03.008_bib0320","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/01.ede.0000152903.55579.15","article-title":"Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis","volume":"16","author":"Moretti","year":"2005","journal-title":"Epidemiology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0325","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/aje\/kwn331","article-title":"Neural tube defects and maternal folate intake among pregnancies conceived after folic acid fortification in the United States","volume":"169","author":"Mosley","year":"2009","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0330","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s10654-009-9401-4","article-title":"Paternal exposure to agent orange and spina bifida: a meta-analysis","volume":"25","author":"Ngo","year":"2010","journal-title":"EurJ Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0335","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/ajim.4700200403","article-title":"Paternal occupation and congenital anomalies in offspring","volume":"20","author":"Olshan","year":"1991","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0340","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1111\/j.1471-0528.1992.tb14411.x","article-title":"Previous miscarriage and stillbirth as risk factors for other unfavourable outcomes in the next pregnancy","volume":"99","author":"Paz","year":"1992","journal-title":"Br. J. Obstet. Gynaecol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0345","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1034\/j.1399-0004.2003.00161.x","article-title":"Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype","volume":"64","author":"Relton","year":"2003","journal-title":"Clin. Genet."},{"key":"10.1016\/j.neuro.2016.03.008_bib0350","doi-asserted-by":"crossref","first-page":"12770","DOI":"10.1073\/pnas.1105209108","article-title":"Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects","volume":"108","author":"Ren","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuro.2016.03.008_bib0355","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/aje\/kwj101","article-title":"Neural tube defects and maternal residential proximity to agricultural pesticide applications","volume":"163","author":"Rull","year":"2006","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0360","doi-asserted-by":"crossref","first-page":"212","DOI":"10.5271\/sjweh.871","article-title":"Reproductive outcomes among hairdressers","volume":"31","author":"Rylander","year":"2005","journal-title":"Scand. J. Work Environ. Health"},{"key":"10.1016\/j.neuro.2016.03.008_bib0365","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1469-8749.1992.tb11502.x","article-title":"Neural tube defect etiology: new evidence concerning maternal hyperthermia, health and diet","volume":"34","author":"Sandford","year":"1992","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0370","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.pcl.2010.07.009","article-title":"Children with spina bifida: key clinical issues","volume":"57","author":"Sandler","year":"2010","journal-title":"Pediatr. Clin. North Am."},{"key":"10.1016\/j.neuro.2016.03.008_bib0375","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1002\/bdra.20624","article-title":"Maternal caffeine consumption and risk of neural tube defects","volume":"85","author":"Schmidt","year":"2009","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0380","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/EDE.0b013e3181761fa3","article-title":"Prepregnant obesity and risks of selected birth defects in offspring","volume":"19","author":"Shaw","year":"2008","journal-title":"Epidemiology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0385","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1001\/jama.1996.03530380035028","article-title":"Risk of neural tube defect-affected pregnancies among obese women","volume":"275","author":"Shaw","year":"1996","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.neuro.2016.03.008_bib0390","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/ije\/30.1.60","article-title":"Lowered weight gain during pregnancy and risk of neural tube defects among offspring","volume":"30","author":"Shaw","year":"2001","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0395","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1046\/j.1365-3016.2002.00436.x","article-title":"Paternal occupational group and risk of offspring with neural tube defects","volume":"16","author":"Shaw","year":"2002","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0400","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1002\/bdra.10129","article-title":"Differential risks to males and females for congenital malformations among 2.5 million California births, 1989\u20131997","volume":"67","author":"Shaw","year":"2003","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0405","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1093\/ajcn\/78.5.972","article-title":"Neural tube defects associated with maternal periconceptional dietary intake of simple sugars and glycemic index","volume":"78","author":"Shaw","year":"2003","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.neuro.2016.03.008_bib0410","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1093\/aje\/kwh187","article-title":"Periconceptional dietary intake of choline and betaine and neural tube defects in offspring","volume":"160","author":"Shaw","year":"2004","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0415","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/bdra.20112","article-title":"Periconceptional dietary intake of myo-inositol and neural tube defects in offspring","volume":"73","author":"Shaw","year":"2005","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0420","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1365-3016.2008.00964.x","article-title":"Periconceptional glycaemic load and intake of sugars and their association with neural tube defects in offspring","volume":"22","author":"Shaw","year":"2008","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0425","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1471-2288-7-10","article-title":"Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews","volume":"15","author":"Shea","year":"2007","journal-title":"BMC Med. Res. Methodol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0430","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1542\/peds.2009-2084","article-title":"Prevalence of spina bifida among children and adolescents in 10 regions in the United States","volume":"126","author":"Shin","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.neuro.2016.03.008_bib0435","series-title":"Fact sheets. 20122012","author":"Spina Bifida Association of the United States","year":"2012"},{"key":"10.1016\/j.neuro.2016.03.008_bib0440","series-title":"Spina bifida. 20002012","author":"Spina Bifida","year":"2000"},{"key":"10.1016\/j.neuro.2016.03.008_bib0445","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1001\/jama.2009.113","article-title":"Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis","volume":"301","author":"Stothard","year":"2009","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.neuro.2016.03.008_bib0450","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s10995-005-0031-5","article-title":"The risk of birth defects in multiple births: a population-based study","volume":"10","author":"Tang","year":"2006","journal-title":"Matern. Child Health J."},{"key":"10.1016\/j.neuro.2016.03.008_bib0455","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1097\/GIM.0b013e31821d4188","article-title":"Policy statement on folic acid and neural tube defects","volume":"13","author":"Toriello","year":"2011","journal-title":"Genet. Med."},{"key":"10.1016\/j.neuro.2016.03.008_bib0460","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1365-3016.2006.00722.x","article-title":"Understanding the increased risk of neural tube defect-affected pregnancies among mexico-born women in California: immigration and anthropometric factors","volume":"20","author":"Velie","year":"2006","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0465","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jns.2003.08.014","article-title":"Birth order and neural tube defects: a reappraisal","volume":"217","author":"Vieira","year":"2004","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.neuro.2016.03.008_bib0470","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/tera.10097","article-title":"Apolipoprotein E and apolipoprotein B genotypes and risk for spina bifida","volume":"66","author":"Volcik","year":"2002","journal-title":"Teratology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0475","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1471-0528.2008.01963.x","article-title":"The maternal mediterranean dietary pattern is associated with a reduced risk of spina bifida in the offspring","volume":"116","author":"Vujkovic","year":"2009","journal-title":"Int. J. Obstet. Gynaecol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0480","doi-asserted-by":"crossref","first-page":"389","DOI":"10.3109\/14767058.2011.580800","article-title":"Low maternal vitamin B(12) is a risk factor for neural tube defects: a meta-analysis","volume":"25","author":"Wang","year":"2012","journal-title":"J. Matern. Fetal Neonatal. Med."},{"issue":"14","key":"10.1016\/j.neuro.2016.03.008_bib0485","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1001\/jama.1996.03530380031027","article-title":"Prepregnant weight in relation to risk of neural tube defects","volume":"275","author":"Werler","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.neuro.2016.03.008_bib0490","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/humrep\/del453","article-title":"Paternal age and birth defects: how strong is the association?","volume":"22","author":"Yang","year":"2007","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.neuro.2016.03.008_bib0495","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/aje\/kwm283","article-title":"Socioeconomic status in relation to selected birth defects in a large multi centered US case-control study","volume":"167","author":"Yang","year":"2008","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2016.03.008_bib0500","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1097\/EDE.0b013e31821b4526","article-title":"Tea drinking as a risk factor for neural tube defects in Northern China","volume":"22","author":"Ye","year":"2011","journal-title":"Epidemiology"},{"key":"10.1016\/j.neuro.2016.03.008_bib0505","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00381-010-1198-7","article-title":"A population-based case-control study of risk factors for neural tube defects in Shenyang, China","volume":"27","author":"Yin","year":"2011","journal-title":"Child. Nerv. Syst."},{"key":"10.1016\/j.neuro.2016.03.008_bib0510","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/ije\/21.2.273","article-title":"A case-control study of paternal smoking and birth defects","volume":"21","author":"Zhang","year":"1992","journal-title":"Int. J. Epidemiol."}],"container-title":["NeuroToxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X16300274?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X16300274?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T04:19:11Z","timestamp":1718425151000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161813X16300274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":102,"alternative-id":["S0161813X16300274"],"URL":"https:\/\/doi.org\/10.1016\/j.neuro.2016.03.008","relation":{},"ISSN":["0161-813X"],"issn-type":[{"value":"0161-813X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A systematic review of the risks factors associated with the onset and natural progression of spina bifida","name":"articletitle","label":"Article Title"},{"value":"NeuroToxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuro.2016.03.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}