{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T23:11:45Z","timestamp":1792365105832,"version":"4.4.0"},"reference-count":108,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroToxicology"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.neuro.2022.08.014","type":"journal-article","created":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T11:11:24Z","timestamp":1661598684000},"page":"22-36","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Impact of a bisphenol A, F, and S mixture and maternal care on the brain transcriptome of rat dams and pups"],"prefix":"10.1016","volume":"93","author":[{"given":"H.E.","family":"Lapp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.E.","family":"Margolis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.A.","family":"Champagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuro.2022.08.014_bib1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.neuro.2010.07.008","article-title":"The impact of neonatal bisphenol \u2013 a exposure on sexually dimorphic hypothalamic nuclei in the female rat","volume":"32","author":"Adewale","year":"2011","journal-title":"NeuroToxicology"},{"key":"10.1016\/j.neuro.2022.08.014_bib2","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-29732-9","article-title":"Prenatal bisphenol A exposure is linked to epigenetic changes in glutamate receptor subunit gene Grin2b in female rats and humans","volume":"8","author":"Alavian-Ghavanini","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuro.2022.08.014_bib3","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0304-3940(01)02092-4","article-title":"Bisphenol-A differently affects estrogen receptors-alpha in estrous-cycling and lactating female rats","volume":"310","author":"Aloisi","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuro.2022.08.014_bib4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.mce.2011.12.012","article-title":"Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways","volume":"355","author":"Alonso-Magdalena","year":"2012","journal-title":"Mol. Cell. Endocrinol., Health Impacts Endocr. Disrupters"},{"key":"10.1016\/j.neuro.2022.08.014_bib5","unstructured":"Andrews, S., 2010. FastQC: A quality control tool for high throughput sequence data."},{"key":"10.1016\/j.neuro.2022.08.014_bib6","doi-asserted-by":"crossref","first-page":"3856","DOI":"10.1210\/en.2016-1339","article-title":"Impact of low dose oral exposure to bisphenol A (BPA) on the neonatal rat hypothalamic and hippocampal transcriptome: a CLARITY-BPA consortium study","volume":"157","author":"Arambula","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib7","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.neuro.2017.10.005","article-title":"Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study","volume":"65","author":"Arambula","year":"2018","journal-title":"NeuroToxicology"},{"key":"10.1016\/j.neuro.2022.08.014_bib8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc.: Ser. B"},{"key":"10.1016\/j.neuro.2022.08.014_bib9","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/87565649809540708","article-title":"How hormones affect behavioral and neural development: introduction to the special issue on \u201cgonadal hormones and sex differences in behavior","volume":"14","author":"Berenbaum","year":"1998","journal-title":"Dev. Neuropsychol."},{"key":"10.1016\/j.neuro.2022.08.014_bib10","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/1541-4337.12028","article-title":"Migration of chemical compounds from packaging polymers during icrowave, conventional heat treatment, and storage","volume":"12","author":"Bhunia","year":"2013","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.neuro.2022.08.014_bib11","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.chemosphere.2017.05.070","article-title":"Bisphenol A and replacements in thermal paper: a review","volume":"182","author":"Bj\u00f6rnsdotter","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.neuro.2022.08.014_bib12","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1289\/ehp.98106551","article-title":"Rapid screening of environmental chemicals for estrogen receptor binding capacity","volume":"106","author":"Bolger","year":"1998","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.neuro.2022.08.014_bib13","doi-asserted-by":"crossref","first-page":"17139","DOI":"10.1073\/pnas.0807412105","article-title":"Brain vasopressin is an important regulator of maternal behavior independent of dams\u2019 trait anxiety","volume":"105","author":"Bosch","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuro.2022.08.014_bib14","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1002\/syn.21758","article-title":"Adolescent bisphenol-A exposure decreases dendritic spine density: role of sex and age","volume":"68","author":"Bowman","year":"2014","journal-title":"Synapse"},{"key":"10.1016\/j.neuro.2022.08.014_bib15","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1289\/ehp.7534","article-title":"Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population","volume":"113","author":"Calafat","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.neuro.2022.08.014_bib16","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1038\/sj.npp.1300237","article-title":"Variations in maternal care alter GABAA receptor subunit expression in brain regions associated with fear","volume":"28","author":"Caldji","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuro.2022.08.014_bib17","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/toxsci\/kft035","article-title":"Prenatal bisphenol A exposure alters sex-specific estrogen receptor expression in the neonatal rat hypothalamus and amygdala","volume":"133","author":"Cao","year":"2013","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.neuro.2022.08.014_bib18","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.chemosphere.2012.05.003","article-title":"Bisphenol A in human placental and fetal liver tissues collected from Greater Montreal area (Quebec) during 1998\u20132008","volume":"89","author":"Cao","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.neuro.2022.08.014_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2020.00453","article-title":"Bisphenol A-induced epigenetic changes and its effects on the male reproductive system","volume":"11","author":"Cariati","year":"2020","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.neuro.2022.08.014_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073584","article-title":"Effects of adult exposure to bisphenol A on genes involved in the physiopathology of rat prefrontal cortex","volume":"8","author":"Castro","year":"2013","journal-title":"PLOS One"},{"key":"10.1016\/j.neuro.2022.08.014_bib21","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.envres.2015.07.001","article-title":"Bisphenol A, bisphenol F and bisphenol S affect differently 5\u03b1-reductase expression and dopamine\u2013serotonin systems in the prefrontal cortex of juvenile female rats","volume":"142","author":"Castro","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.neuro.2022.08.014_bib22","first-page":"516","article-title":"Bisphenol S (BPS) alters maternal behavior and brain in mice exposed during pregnancy\/lactation and their daughters","volume":"158","author":"Catanese","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib23","doi-asserted-by":"crossref","first-page":"12736","DOI":"10.1073\/pnas.221224598","article-title":"Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors","volume":"98","author":"Champagne","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuro.2022.08.014_bib24","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1210\/en.2003-0564","article-title":"Natural variations in maternal care are associated with estrogen receptor alpha expression and estrogen sensitivity in the medial preoptic area","volume":"144","author":"Champagne","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib25","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0031-9384(03)00149-5","article-title":"Variations in maternal care in the rat as a mediating influence for the effects of environment on development","volume":"79","author":"Champagne","year":"2003","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuro.2022.08.014_bib26","doi-asserted-by":"crossref","first-page":"4113","DOI":"10.1523\/JNEUROSCI.5322-03.2004","article-title":"Variations in nucleus accumbens dopamine associated with individual differences in maternal behavior in the rat","volume":"24","author":"Champagne","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuro.2022.08.014_bib27","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1210\/en.2005-1119","article-title":"Maternal care associated with methylation of the estrogen receptor-\u03b11b promoter and estrogen receptor-\u03b1 expression in the medial preoptic area of female offspring","volume":"147","author":"Champagne","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib28","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1039\/C6TX00047A","article-title":"Epigenetic disruption and glucose homeostasis changes following low-dose maternal bisphenol A exposure","volume":"5","author":"Chang","year":"2016","journal-title":"Toxicol. Res."},{"key":"10.1016\/j.neuro.2022.08.014_bib29","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1080\/15592294.2018.1497388","article-title":"Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study","volume":"13","author":"Cheong","year":"2018","journal-title":"Epigenetics"},{"key":"10.1016\/j.neuro.2022.08.014_bib30","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1476-069X-10-94","article-title":"Biomonitoring of bisphenol A concentrations in maternal and umbilical cord blood in regard to birth outcomes and adipokine expression: a birth cohort study in Taiwan","volume":"10","author":"Chou","year":"2011","journal-title":"Environ. Health"},{"key":"10.1016\/j.neuro.2022.08.014_bib31","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.yhbeh.2010.07.008","article-title":"Gestational exposure to bisphenol A and cross-fostering affect behaviors in juvenile mice","volume":"58","author":"Cox","year":"2010","journal-title":"Horm. Behav."},{"key":"10.1016\/j.neuro.2022.08.014_bib32","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.brainresbull.2004.11.017","article-title":"Bisphenol-A exposure during pregnancy and lactation affects maternal behavior in rats","volume":"65","author":"Della Seta","year":"2005","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.neuro.2022.08.014_bib33","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1210\/en.2017-00730","article-title":"Transgenerational effects of bisphenol A on gene expression and DNA methylation of imprinted genes in brain","volume":"159","author":"Drobn\u00e1","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib34","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.bbi.2011.02.009","article-title":"Epigenetic impact of simulated maternal grooming on estrogen receptor alpha within the developing amygdala","volume":"25","author":"Edelmann","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neuro.2022.08.014_bib35","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jenvman.2012.03.021","article-title":"Bisphenol A exposure, effects, and policy: a wildlife perspective","volume":"104","author":"Flint","year":"2012","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.neuro.2022.08.014_bib36","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1126\/science.286.5442.1155","article-title":"Nongenomic transmission across generations of maternal behavior and stress responses in the rat","volume":"286","author":"Francis","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.neuro.2022.08.014_bib37","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1111\/2041-210X.12584","article-title":"BORIS: a free, versatile open-source event-logging software for video\/audio coding and live observations","volume":"7","author":"Friard","year":"2016","journal-title":"Methods Ecol. Evol."},{"key":"10.1016\/j.neuro.2022.08.014_bib38","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2018.00024","article-title":"The Effects of low-dose Bisphenol A and Bisphenol F on neural differentiation of a fetal brain-derived neural progenitor cell line","volume":"9","author":"Fujiwara","year":"2018","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.neuro.2022.08.014_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105465","article-title":"Phthalates, bisphenols, parabens, and triclocarban in feminine hygiene products from the United States and their implications for human exposure","volume":"136","author":"Gao","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.neuro.2022.08.014_bib40","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1159\/000125230","article-title":"Nuclear estrogen receptor binding in the preoptic area and hypothalamus of pregnancy-terminated rats: correlation with the onset of maternal behavior","volume":"50","author":"Giordano","year":"1989","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib41","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1098\/rstb.2012.0223","article-title":"Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone\u2013serotonin\u2013NGFI-A signalling cascade","volume":"367","author":"Hellstrom","year":"2012","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.neuro.2022.08.014_bib42","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.3390\/ijms21093129","article-title":"Bisphenol A exposure in utero disrupts hypothalamic gene expression particularly genes suspected in autism spectrum disorders and neuron and hormone signaling","volume":"21","author":"Henriksen","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuro.2022.08.014_bib43","first-page":"91","article-title":"Bisphenol A (BPA) in China: a review of sources, environmental levels, and potential human health impacts","volume":"42","author":"Huang","year":"2012","journal-title":"Environ. Int., Emerg. Environ. Health Issues Mod. China"},{"key":"10.1016\/j.neuro.2022.08.014_bib44","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1093\/humrep\/17.11.2839","article-title":"Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure","author":"Ikezuki","year":"2002","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.neuro.2022.08.014_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121774","article-title":"Prenatal exposure to bisphenol A and its alternatives and child neurodevelopment at 2 years","volume":"388","author":"Jiang","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.neuro.2022.08.014_bib46","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222413201","article-title":"Autism-related transcription factors underlying the sex-specific effects of prenatal bisphenol A exposure on transcriptome-interactome profiles in the offspring prefrontal cortex","volume":"22","author":"Kanlayaprasit","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuro.2022.08.014_bib47","doi-asserted-by":"crossref","DOI":"10.1002\/bies.201600159","article-title":"The neurobiology of parenting: a neural circuit perspective","volume":"39","author":"Kohl","year":"2017","journal-title":"BioEssays"},{"key":"10.1016\/j.neuro.2022.08.014_bib48","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/j.1365-2826.2012.02280.x","article-title":"Maternal contact differentially modulates central and peripheral oxytocin in rat pups during a brief regime of mother\u2013pup interaction that induces a filial huddling preference","volume":"24","author":"Kojima","year":"2012","journal-title":"J. Neuroendocr."},{"key":"10.1016\/j.neuro.2022.08.014_bib49","article-title":"Fast gene set enrichment analysis","author":"Korotkevich","year":"2016","journal-title":"Bioinformatics"},{"key":"10.1016\/j.neuro.2022.08.014_bib50","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.tox.2007.12.028","article-title":"Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor","volume":"246","author":"Kr\u00fcger","year":"2008","journal-title":"Toxicology"},{"key":"10.1016\/j.neuro.2022.08.014_bib51","doi-asserted-by":"crossref","first-page":"4252","DOI":"10.1210\/endo.139.10.6216","article-title":"Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor \u03b2","volume":"139","author":"Kuiper","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib52","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.bbi.2011.02.005","article-title":"Epigenetic perspective on the developmental effects of bisphenol A","volume":"25","author":"Kundakovic","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neuro.2022.08.014_bib53","doi-asserted-by":"crossref","first-page":"9956","DOI":"10.1073\/pnas.1214056110","article-title":"Sex-specific epigenetic disruption and behavioral changes following low-dose in utero bisphenol A exposure","volume":"110","author":"Kundakovic","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuro.2022.08.014_bib54","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1210\/en.2009-0649","article-title":"Sex differences in epigenetic regulation of the estrogen receptor-\u03b1 promoter within the developing preoptic area","volume":"151","author":"Kurian","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib55","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.envres.2015.06.013","article-title":"Temporal trends in bisphenol A exposure in the United States from 2003\u20132012 and factors associated with BPA exposure: spot samples and urine dilution complicate data interpretation","volume":"142","author":"LaKind","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.neuro.2022.08.014_bib56","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neuro.2022.08.014_bib57","doi-asserted-by":"crossref","first-page":"6523","DOI":"10.1021\/acsomega.8b00824","article-title":"Exposure to bisphenol A, bisphenol F, and bisphenol S in U.S. adults and Children: The National Health and Nutrition Examination Survey 2013\u20132014","volume":"3","author":"Lehmler","year":"2018","journal-title":"ACS Omega"},{"key":"10.1016\/j.neuro.2022.08.014_bib58","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1021\/jf400445n","article-title":"Concentrations and profiles of bisphenol A and other bisphenol analogues in foodstuffs from the United States and their implications for human exposure","volume":"61","author":"Liao","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.neuro.2022.08.014_bib59","doi-asserted-by":"crossref","first-page":"6860","DOI":"10.1021\/es301334j","article-title":"Bisphenol S in urine from the United States and seven asian countries: occurrence and human exposures","volume":"46","author":"Liao","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.neuro.2022.08.014_bib60","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1126\/science.277.5332.1659","article-title":"Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress","volume":"277","author":"Liu","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.neuro.2022.08.014_bib61","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/77702","article-title":"Maternal care, hippocampal synaptogenesis and cognitive development in rats","volume":"3","author":"Liu","year":"2000","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuro.2022.08.014_bib62","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1111\/1755-0998.12529","article-title":"Evaluation of TagSeq, a reliable low-cost alternative for RNAseq","volume":"16","author":"Lohman","year":"2016","journal-title":"Mol. Ecol. Resour."},{"key":"10.1016\/j.neuro.2022.08.014_bib63","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.neuro.2022.08.014_bib64","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2018.00508","article-title":"Weighted gene correlation network analysis (WGCNA) reveals novel transcription factors associated with bisphenol A dose-response","volume":"9","author":"Maertens","year":"2018","journal-title":"Front. Genet."},{"key":"10.1016\/j.neuro.2022.08.014_bib65","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2019.00951","article-title":"Perinatal bisphenol A exposure and reprogramming of imprinted gene expression in the adult mouse brain","volume":"10","author":"Malloy","year":"2019","journal-title":"Front. Genet."},{"key":"10.1016\/j.neuro.2022.08.014_bib66","doi-asserted-by":"crossref","first-page":"10","DOI":"10.14806\/ej.17.1.200","article-title":"Cutadapt removes adapter sequences from high-throughput sequencing reads","volume":"17","author":"Martin","year":"2011","journal-title":"EMBnet. J."},{"key":"10.1016\/j.neuro.2022.08.014_bib67","first-page":"3599","article-title":"Profiling gene expression responses of coral larvae (Acropora millepora) to elevated temperature and settlement inducers using a novel RNA-Seq procedure","volume":"20","author":"Meyer","year":"2011","journal-title":"Mol. Ecol."},{"key":"10.1016\/j.neuro.2022.08.014_bib68","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.toxlet.2009.06.861","article-title":"Bisphenol A levels in blood depend on age and exposure","volume":"190","author":"Mielke","year":"2009","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.neuro.2022.08.014_bib69","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1037\/h0077599","article-title":"Mother rats interact differently with male amd female offspring","volume":"93","author":"Moore","year":"1979","journal-title":"J. Comp. Physiol. Psychol."},{"key":"10.1016\/j.neuro.2022.08.014_bib70","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuro.2015.06.002","article-title":"Bisphenol A: human exposure and neurobehavior","volume":"49","author":"Mustieles","year":"2015","journal-title":"NeuroToxicology"},{"key":"10.1016\/j.neuro.2022.08.014_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106078","article-title":"A comprehensive review of the neurobehavioral effects of bisphenol S and the mechanisms of action: new insights from in vitro and in vivo models","volume":"145","author":"Naderi","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.neuro.2022.08.014_bib72","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1002\/jnr.21020","article-title":"Murine neocortical histogenesis is perturbed by prenatal exposure to low doses of bisphenol A","volume":"84","author":"Nakamura","year":"2006","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neuro.2022.08.014_bib73","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.neulet.2007.02.093","article-title":"Prenatal exposure to bisphenol A affects adult murine neocortical structure","volume":"420","author":"Nakamura","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuro.2022.08.014_bib74","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.neulet.2006.04.014","article-title":"Prenatal and neonatal exposure to low-dose of bisphenol-A enhance the morphine-induced hyperlocomotion and rewarding effect","volume":"402","author":"Narita","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuro.2022.08.014_bib75","doi-asserted-by":"crossref","first-page":"3226","DOI":"10.3390\/molecules23123226","article-title":"Binary mixtures of selected bisphenols in the environment: their toxicity in relationship to individual constituents","volume":"23","author":"Owczarek","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.neuro.2022.08.014_bib76","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1289\/ehp.02110s3415","article-title":"Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice","volume":"110","author":"Palanza","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.neuro.2022.08.014_bib77","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3389\/fncel.2019.00218","article-title":"Roles of primary cilia in the developing brain","volume":"13","author":"Park","year":"2019","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.neuro.2022.08.014_bib78","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12730","article-title":"Achieving CLARITY on bisphenol A, brain and behaviour","volume":"32","author":"Patisaul","year":"2020","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.neuro.2022.08.014_bib79","doi-asserted-by":"crossref","first-page":"4340","DOI":"10.1210\/en.2013-1595","article-title":"Developmental timing of the effects of maternal care on gene expression and epigenetic regulation of hormone receptor levels in female rats","volume":"154","author":"Pe\u00f1a","year":"2013","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuro.2022.08.014_bib80","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1096\/fj.02-0313fje","article-title":"Low doses of the endocrine disruptor Bisphenol-A and the native hormone 17\u03b2-estradiol rapidly activate the transcription factor CREB","volume":"16","author":"Quesada","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.neuro.2022.08.014_bib81","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.lfs.2018.10.044","article-title":"Bisphenol A: what lies beneath its induced diabetes and the epigenetic modulation?","volume":"214","author":"Rahmani","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.neuro.2022.08.014_bib82","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/toxsci\/kfu074","article-title":"Investigation of the effects of subchronic low dose oral exposure to bisphenol A (BPA) and ethinyl estradiol (EE) on estrogen receptor expression in the juvenile and adult female rat hypothalamus","volume":"140","author":"Rebuli","year":"2014","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.neuro.2022.08.014_bib83","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1289\/ehp.9804","article-title":"Estradiol and bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate mesenchyme cells","volume":"115","author":"Richter","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.neuro.2022.08.014_bib84","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.reprotox.2013.08.008","article-title":"Bisphenol A and human health: a review of the literature","volume":"42","author":"Rochester","year":"2013","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.neuro.2022.08.014_bib85","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1289\/ehp.1408989","article-title":"Bisphenol S and F: a systematic review and comparison of the hormonal activity of bisphenol A substitutes","volume":"123","author":"Rochester","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.neuro.2022.08.014_bib86","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.envint.2017.12.028","article-title":"Prenatal exposure to bisphenol A and hyperactivity in children: a systematic review and meta-analysis","volume":"114","author":"Rochester","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.neuro.2022.08.014_bib87","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1651-2227.1994.tb13259.x","article-title":"Psychobiology of maternal behavior: contribution to the clinical understanding of maternal behavior among humans","volume":"397","author":"Rosenblatt","year":"1994","journal-title":"Acta Paediatr. Suppl."},{"key":"10.1016\/j.neuro.2022.08.014_bib88","series-title":"Progress in Brain Research, The Maternal Brain","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0079-6123(01)33002-9","article-title":"Chapter 1 Brain preparations for maternity \u2013 adaptive changes in behavioral and neuroendocrine systems during pregnancy and lactation. An overview","author":"Russell","year":"2001"},{"key":"10.1016\/j.neuro.2022.08.014_bib89","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.taap.2011.12.018","article-title":"Low concentrations of bisphenol a suppress thyroid hormone receptor transcription through a nongenomic mechanism","volume":"259","author":"Sheng","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.neuro.2022.08.014_bib90","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/0018-506X(78)90054-5","article-title":"Duration of estrogen stimulation and progesterone inhibition of maternal behavior in pregnancy-terminated rats","volume":"11","author":"Siegel","year":"1978","journal-title":"Horm. Behav."},{"key":"10.1016\/j.neuro.2022.08.014_bib91","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1556\/004.2016.046","article-title":"Bisphenol A influences oestrogen- and thyroid hormone-regulated thyroid hormone receptor expression in rat cerebellar cell culture","volume":"64","author":"Somogyi","year":"2016","journal-title":"Acta Vet. Hung."},{"key":"10.1016\/j.neuro.2022.08.014_bib92","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/dev.21182","article-title":"Natural variation in maternal care shapes adult social behavior in rats","volume":"56","author":"Starr-Phillips","year":"2014","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.neuro.2022.08.014_bib93","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1002\/aur.1444","article-title":"Bisphenol A exposure in children with autism spectrum disorders","volume":"8","author":"Stein","year":"2015","journal-title":"Autism Res."},{"key":"10.1016\/j.neuro.2022.08.014_bib94","doi-asserted-by":"crossref","DOI":"10.1093\/eep\/dvy022","article-title":"Impacts of bisphenol A (BPA) and phthalate exposures on epigenetic outcomes in the human placenta","volume":"4","author":"Strakovsky","year":"2018","journal-title":"Environ. Epigenet."},{"key":"10.1016\/j.neuro.2022.08.014_bib95","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuro.2022.08.014_bib96","doi-asserted-by":"crossref","first-page":"9487","DOI":"10.1038\/s41598-020-65229-0","article-title":"Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer\u2019s disease in the offspring hippocampus","volume":"10","author":"Sukjamnong","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuro.2022.08.014_bib97","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0306-4522(02)00935-1","article-title":"Prenatal and neonatal exposure to bisphenol-a enhances the central dopamine d1 receptor-mediated action in mice: enhancement of the methamphetamine-induced abuse state","volume":"117","author":"Suzuki","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuro.2022.08.014_bib98","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.yfrne.2005.10.002","article-title":"Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat","volume":"26","author":"Szyf","year":"2005","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.neuro.2022.08.014_bib99","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.cbi.2013.03.013","article-title":"Bisphenol A affects androgen receptor function via multiple mechanisms","volume":"203","author":"Teng","year":"2013","journal-title":"Chem. -Biol. Interact."},{"key":"10.1016\/j.neuro.2022.08.014_bib100","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1038\/s41598-019-39386-w","article-title":"Sex differences in the effects of prenatal bisphenol A exposure on genes associated with Autism Spectrum Disorder in the hippocampus","volume":"9","author":"Thongkorn","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuro.2022.08.014_bib101","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1038\/s41598-020-80390-2","article-title":"Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions","volume":"11","author":"Thongkorn","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuro.2022.08.014_bib102","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1289\/ehp.0901716","article-title":"Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A","volume":"118","author":"Vandenberg","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.neuro.2022.08.014_bib103","doi-asserted-by":"crossref","DOI":"10.4161\/endo.25411","article-title":"Rapid estrogenic signaling activities of the modified (chlorinated, sulfonated, and glucuronidated) endocrine disruptor bisphenol A","volume":"1","author":"Vi\u00f1as","year":"2013","journal-title":"Endocr. Disruptors"},{"key":"10.1016\/j.neuro.2022.08.014_bib104","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/nn1276","article-title":"Epigenetic programming by maternal behavior","volume":"7","author":"Weaver","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuro.2022.08.014_bib105","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.neuro.2019.06.007","article-title":"Perinatal bisphenol A (BPA) exposure alters brain oxytocin receptor (OTR) expression in a sex- and region- specific manner: a CLARITY-BPA consortium follow-up study","volume":"74","author":"Witchey","year":"2019","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neuro.2022.08.014_bib106","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.yhbeh.2010.10.001","article-title":"The role of Bisphenol A in shaping the brain, epigenome and behavior","volume":"59","author":"Wolstenholme","year":"2011","journal-title":"Horm. Behav., Spec. Issue.: Behav. Epigenetics"},{"key":"10.1016\/j.neuro.2022.08.014_bib107","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105407","article-title":"Concentrations of bisphenol A and its alternatives in paired maternal\u2013fetal urine, serum and amniotic fluid from an e-waste dismantling area in China","volume":"136","author":"Zhang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.neuro.2022.08.014_bib108","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.chemosphere.2013.12.085","article-title":"Determination of free Bisphenol A (BPA) concentrations in breast milk of U.S. women using a sensitive LC\/MS\/MS method","volume":"104","author":"Zimmers","year":"2014","journal-title":"Chemosphere"}],"container-title":["NeuroToxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X22001371?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X22001371?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T14:25:33Z","timestamp":1758983133000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161813X22001371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":108,"alternative-id":["S0161813X22001371"],"URL":"https:\/\/doi.org\/10.1016\/j.neuro.2022.08.014","relation":{},"ISSN":["0161-813X"],"issn-type":[{"value":"0161-813X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of a bisphenol A, F, and S mixture and maternal care on the brain transcriptome of rat dams and pups","name":"articletitle","label":"Article Title"},{"value":"NeuroToxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuro.2022.08.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}