{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T13:58:49Z","timestamp":1776347929518,"version":"3.51.2"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","award":["825759"],"award-info":[{"award-number":["825759"]}],"id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroToxicology"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.neuro.2023.05.004","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T11:41:56Z","timestamp":1683546116000},"page":"34-46","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Epigenetics of methylmercury"],"prefix":"10.1016","volume":"97","author":[{"given":"Andrea","family":"Cediel-Ulloa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Lindner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00eblle","family":"R\u00fcegg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Broberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.neuro.2023.05.004_bib1","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1093\/nar\/gkz097","article-title":"An estimate of the total number of true human miRNAs","volume":"47","author":"Alles","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.neuro.2023.05.004_bib2","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1080\/15592294.2017.1320637","article-title":"Prenatal exposure to neurotoxic metals is associated with increased placental glucocorticoid receptor DNA methylation","volume":"12","author":"Appleton","year":"2017","journal-title":"Epigenetics"},{"issue":"3","key":"10.1016\/j.neuro.2023.05.004_bib3","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1080\/15592294.2021.1897059","article-title":"Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)","volume":"17","author":"Aung","year":"2022","journal-title":"Epigenetics"},{"key":"10.1016\/j.neuro.2023.05.004_bib4","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1126\/science.181.4096.230","article-title":"Methylmercury poisoning in Iraq","volume":"181","author":"Bakir","year":"1973","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.neuro.2023.05.004_bib5","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1093\/ije\/dyv032","article-title":"Prenatal mercury concentration is associated with changes in DNA methylation at TCEANC2 in newborns","volume":"44","author":"Bakulski","year":"2015","journal-title":"Int. J. Epidemiol."},{"issue":"6","key":"10.1016\/j.neuro.2023.05.004_bib6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/nrn3818","article-title":"Epigenetic and transgenerational reprogramming of brain development","volume":"16","author":"Bale","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuro.2023.05.004_bib7","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ijheh.2018.07.011","article-title":"Prenatal mercury exposure and child neurodevelopment outcomes at 18 months: results from the Mediterranean PHIME cohort","volume":"222","author":"Barbone","year":"2019","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.neuro.2023.05.004_bib8","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.cbpc.2013.02.004","article-title":"Effects of methylmercury on epigenetic markers in three model species: mink, chicken and yellow perch","volume":"157","author":"Basu","year":"2013","journal-title":"Comp. Biochem Physiol. C. Toxicol. Pharm."},{"issue":"4","key":"10.1016\/j.neuro.2023.05.004_bib9","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s40471-020-00249-y","article-title":"Associations of metals and neurodevelopment: a review of recent evidence on susceptibility factors","volume":"7","author":"Bauer","year":"2020","journal-title":"Curr. Epidemiol. Rep."},{"key":"10.1016\/j.neuro.2023.05.004_bib10","doi-asserted-by":"crossref","first-page":"S186","DOI":"10.1016\/j.psyneuen.2009.05.021","article-title":"The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders","volume":"34","author":"Binder","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuro.2023.05.004_bib11","doi-asserted-by":"crossref","first-page":"333","DOI":"10.2217\/epi-2016-0112","article-title":"Effects of prenatal exposure to endocrine disruptors and toxic metals on the fetal epigenome","volume":"9","author":"Bommarito","year":"2017","journal-title":"Epigenomics"},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib12","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/toxsci\/kfs257","article-title":"Inherited effects of low-dose exposure to methylmercury in neural stem cells","volume":"130","author":"Bose","year":"2012","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.neuro.2023.05.004_bib13","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1017\/S2040174414000221","article-title":"Arsenic exposure in early pregnancy alters genome-wide DNA methylation in cord blood particularly in boys","volume":"5","author":"Broberg","year":"2014","journal-title":"J. Dev. Orig. Health Dis."},{"key":"10.1016\/j.neuro.2023.05.004_bib14","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/nsmb.2489","article-title":"Epigenetic programming and reprogramming during development","volume":"20","author":"Cantone","year":"2013","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"6","key":"10.1016\/j.neuro.2023.05.004_bib15","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1080\/15592294.2015.1046026","article-title":"Differential DNA methylation in umbilical cord blood of infants exposed to mercury and arsenic in utero","volume":"10","author":"Cardenas","year":"2015","journal-title":"Epigenetics"},{"issue":"8","key":"10.1016\/j.neuro.2023.05.004_bib16","doi-asserted-by":"crossref","DOI":"10.1289\/EHP1467","article-title":"Prenatal exposure to mercury: associations with global DNA methylation and hydroxymethylation in cord blood and in childhood","volume":"125","author":"Cardenas","year":"2017","journal-title":"Environ. Health Perspect."},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib17","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/s41598-017-00384-5","article-title":"Persistent DNA methylation changes associated with prenatal mercury exposure and cognitive performance during childhood","volume":"7","author":"Cardenas","year":"2017","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.neuro.2023.05.004_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176155","article-title":"Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish","volume":"12","author":"Carvan","year":"2017","journal-title":"PloS One"},{"key":"10.1016\/j.neuro.2023.05.004_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106321","article-title":"Prenatal methylmercury exposure and DNA methylation in seven-year-old children in the seychelles child development study","volume":"147","author":"Cediel Ulloa","year":"2021","journal-title":"Environ. Int"},{"key":"10.1016\/j.neuro.2023.05.004_bib20","first-page":"2553","article-title":"Methylmercury-induced D.N.A. methylation\u2014From epidemiological observations to experimental evidence","author":"Cediel-Ulloa","year":"2022","journal-title":"Front Genet"},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib21","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s40169-019-0240-y","article-title":"Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer","volume":"8","author":"Chirshev","year":"2019","journal-title":"Clin. Transl. Med."},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib22","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0013-9351(86)80058-5","article-title":"Changes in the molecular structure of mouse fetal astrocyte nucleosomes produced in vitro by methylmercuric chloride","volume":"39","author":"Choi","year":"1986","journal-title":"Environ. Res."},{"key":"10.1016\/j.neuro.2023.05.004_bib23","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3390\/toxics7040056","article-title":"Methylmercury Epigenetics","volume":"7","author":"Culbreth","year":"2019","journal-title":"Toxics"},{"issue":"6","key":"10.1016\/j.neuro.2023.05.004_bib24","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.cell.2008.07.019","article-title":"Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants","volume":"134","author":"Dai","year":"2008","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.neuro.2023.05.004_bib25","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1177\/1091581809337918","article-title":"Effects of mixtures of polychlorinated biphenyls, methylmercury, and organochlorine pesticides on hepatic DNA methylation in prepubertal female Sprague-Dawley rats","volume":"28","author":"Desaulniers","year":"2009","journal-title":"Int. J. Toxicol."},{"issue":"7","key":"10.1016\/j.neuro.2023.05.004_bib26","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/s41580-018-0008-z","article-title":"Dynamics of the epigenetic landscape during the maternal-to-zygotic transition","volume":"19","author":"Eckersley-Maslin","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib27","doi-asserted-by":"crossref","DOI":"10.1093\/eep\/dvv007","article-title":"Prenatal lead exposure is associated with decreased cord blood DNA methylation of the glycoprotein VI gene involved in platelet activation and thrombus formation","volume":"1","author":"Engstr\u00f6m","year":"2015","journal-title":"Environ. Epigenet"},{"issue":"5","key":"10.1016\/j.neuro.2023.05.004_bib28","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/ncb3147","article-title":"The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine","volume":"17","author":"Etchegaray","year":"2015","journal-title":"Nat. Cell Biol."},{"issue":"8","key":"10.1016\/j.neuro.2023.05.004_bib29","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1007\/s00204-018-2239-3","article-title":"Prenatal arsenic exposure is associated with increased plasma IGFBP3 concentrations in 9-year-old children partly via changes in DNA methylation","volume":"92","author":"Gliga","year":"2018","journal-title":"Arch. Toxicol."},{"issue":"4","key":"10.1016\/j.neuro.2023.05.004_bib30","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.bbrc.2018.05.162","article-title":"Methylmercury causes epigenetic suppression of the tyrosine hydroxylase gene in an in vitro neuronal differentiation model","volume":"502","author":"Go","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.neuro.2023.05.004_bib31","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s00204-021-02984-7","article-title":"DNA methyltransferase-and histone deacetylase-mediated epigenetic alterations induced by low-level methylmercury exposure disrupt neuronal development","volume":"95","author":"Go","year":"2021","journal-title":"Arch. Toxicol."},{"issue":"3","key":"10.1016\/j.neuro.2023.05.004_bib32","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/em.21763","article-title":"Mercury biomarkers and DNA methylation among Michigan dental professionals","volume":"54","author":"Goodrich","year":"2013","journal-title":"Environ. Mol. Mutagen"},{"key":"10.1016\/j.neuro.2023.05.004_bib33","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0892-0362(97)00097-4","article-title":"Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury","volume":"19","author":"Grandjean","year":"1997","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.neuro.2023.05.004_bib34","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.neuro.2015.11.007","article-title":"Methylmercury upregulates RE-1 silencing transcription factor (REST) in SH-SY5Y cells and mouse cerebellum","volume":"52","author":"Guida","year":"2016","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neuro.2023.05.004_bib35","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3389\/fnins.2017.00008","article-title":"p38\/Sp1\/Sp4\/HDAC4\/BDNF axis is a novel molecular pathway of the neurotoxic effect of the methylmercury","volume":"11","author":"Guida","year":"2017","journal-title":"Front. Neurosci."},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib36","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1093\/toxsci\/kfy051","article-title":"The miR206-JunD circuit mediates the neurotoxic effect of methylmercury in cortical neurons","volume":"163","author":"Guida","year":"2018","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.neuro.2023.05.004_bib37","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.envint.2017.02.004","article-title":"Methylmercury exposure and cognitive abilities and behavior at 10 years of age","volume":"102","author":"Gustin","year":"2017","journal-title":"Environ. Int"},{"key":"10.1016\/j.neuro.2023.05.004_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408449509089885","article-title":"Minamata disease: methylmercury poisoning in Japan caused by environmental pollution","volume":"25","author":"Harada","year":"1995","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.neuro.2023.05.004_bib39","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.neubiorev.2014.03.012","article-title":"The serotonin-BDNF duo: developmental implications for the vulnerability to psychopathology","volume":"43","author":"Homberg","year":"2014","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.neuro.2023.05.004_bib40","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.scitotenv.2017.07.036","article-title":"Comprehensive gene and microRNA expression profiling on cardiovascular system in zebrafish co-exposured of SiNPs and MeHg","volume":"607","author":"Hu","year":"2017","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1399-0004.2011.01673.x","article-title":"DNA methylation in neurodegenerative disorders: a missing link between genome and environment?","volume":"80","author":"Iraola-Guzm\u00e1n","year":"2011","journal-title":"Clin. Genet"},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib42","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3390\/toxics11010072","article-title":"Epigenetics and methylmercury-induced neurotoxicity, evidence from experimental studies","volume":"11","author":"Ke","year":"2023","journal-title":"Toxics"},{"key":"10.1016\/j.neuro.2023.05.004_bib43","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.tox.2017.05.006","article-title":"Mercury exposure induces cytoskeleton disruption and loss of renal function through epigenetic modulation of MMP9 expression","volume":"386","author":"Khan","year":"2017","journal-title":"Toxicology"},{"key":"10.1016\/j.neuro.2023.05.004_bib44","doi-asserted-by":"crossref","first-page":"494","DOI":"10.4161\/epi.24401","article-title":"Sex-specific effects of early life cadmium exposure on DNA methylation and implications for birth weight","volume":"8","author":"Kippler","year":"2013","journal-title":"Epigenetics"},{"key":"10.1016\/j.neuro.2023.05.004_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106986","article-title":"Marine pollutant exposures and human milk extracellular vesicle-microRNAs in a mother-infant cohort from the Faroe Islands","volume":"158","author":"Kupsco","year":"2022","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib46","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3390\/jcm9010274","article-title":"Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31","volume":"9","author":"Labonne","year":"2020","journal-title":"J. Clin. Med"},{"issue":"3","key":"10.1016\/j.neuro.2023.05.004_bib47","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1080\/15592294.2018.1445901","article-title":"Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort","volume":"13","author":"Leung","year":"2018","journal-title":"Epigenetics"},{"issue":"9","key":"10.1016\/j.neuro.2023.05.004_bib48","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1080\/15592294.2015.1066960","article-title":"Exploring the associations between microRNA expression profiles and environmental pollutants in human placenta from the National Children\u2019s Study (NCS)","volume":"10","author":"Li","year":"2015","journal-title":"Epigenetics"},{"key":"10.1016\/j.neuro.2023.05.004_bib49","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1093\/aje\/kwr328","article-title":"INMA Project. Prenatal exposure to mercury and infant neurodevelopment in a multicenter cohort in Spain: Study of potential modifiers","volume":"175","author":"Llop","year":"2012","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.neuro.2023.05.004_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.157051","article-title":"A multipollutant low-grade exposure regulates the expression of miR-30b, Let-7a and miR-223 in maternal sera: Evidence from the NEHO cohort","volume":"844","author":"Longo","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"Pt B","key":"10.1016\/j.neuro.2023.05.004_bib51","article-title":"DNA methylation changes associated with prenatal mercury exposure: A meta-analysis of prospective cohort studies from PACE consortium","volume":"204","author":"Lozano","year":"2022","journal-title":"Environ. Res"},{"issue":"7","key":"10.1016\/j.neuro.2023.05.004_bib52","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1289\/ehp.1408561","article-title":"Placental DNA Methylation Related to Both Infant Toenail Mercury and Adverse Neurobehavioral Outcomes","volume":"123","author":"Maccani","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.neuro.2023.05.004_bib53","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.cotox.2021.03.002","article-title":"New insights on mechanisms underlying methylmercury-induced and manganese-induced neurotoxicity","volume":"25","author":"Martins","year":"2021","journal-title":"Curr. Opin. Toxicol."},{"issue":"9","key":"10.1016\/j.neuro.2023.05.004_bib54","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/s41576-022-00468-7","article-title":"Histone post-translational modifications - cause and consequence of genome function","volume":"23","author":"Mill\u00e1n-Zambrano","year":"2022","journal-title":"Nat. Rev. Genet"},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib55","doi-asserted-by":"crossref","first-page":"260","DOI":"10.2174\/1570159X14666160709001441","article-title":"MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?","volume":"15","author":"Nadim","year":"2017","journal-title":"Curr. Neuropharmacol."},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib56","doi-asserted-by":"crossref","first-page":"8276","DOI":"10.1038\/s41598-021-87677-y","article-title":"Transgenerational effects in DNA methylation, genotoxicity and reproductive phenotype by chronic arsenic exposure","volume":"11","author":"Nava-Rivera","year":"2021","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib57","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2174\/2211536605666160825151201","article-title":"miRNA-Dependent Activation of mRNA Translation","volume":"5","author":"Ni","year":"2016","journal-title":"Microrna"},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib58","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1021\/acs.chemrestox.1c00306","article-title":"MicroRNA Expression Influences Methylmercury-Induced Lipid Accumulation and Mitochondrial Toxicity in Caenorhabditis elegans","volume":"35","author":"Nielsen","year":"2021","journal-title":"Chem. Res. Toxicol."},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib59","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1017\/S2040174420000161","article-title":"Association between mercury in cord serum and sex-specific DNA methylation in cord tissues","volume":"12","author":"Nishizawa-Jotaki","year":"2021","journal-title":"J. Dev. Orig. Health Dis."},{"key":"10.1016\/j.neuro.2023.05.004_bib60","series-title":"Handbook of the Toxicology of Metals","author":"Nordberg","year":"2021"},{"key":"10.1016\/j.neuro.2023.05.004_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109573","article-title":"Individual species and cumulative mixture relationships of 24-hour urine metal concentrations with DNA methylation age variables in older men","volume":"186","author":"Nwanaji-Enwerem","year":"2020","journal-title":"Environ. Res"},{"key":"10.1016\/j.neuro.2023.05.004_bib62","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.cbpc.2014.05.004","article-title":"Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations","volume":"165","author":"Olsvik","year":"2014","journal-title":"Comp. Biochem Physiol. C. Toxicol. Pharm."},{"issue":"3","key":"10.1016\/j.neuro.2023.05.004_bib63","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1111\/j.1471-4159.2008.05484.x","article-title":"Long\u2010lasting depression\u2010like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury","volume":"106","author":"Onishchenko","year":"2008","journal-title":"J. Neurochem"},{"issue":"4","key":"10.1016\/j.neuro.2023.05.004_bib64","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s10565-013-9250-5","article-title":"miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing","volume":"29","author":"Pallocca","year":"2013","journal-title":"Cell Biol. Toxicol."},{"key":"10.1016\/j.neuro.2023.05.004_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114099","article-title":"Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage","volume":"245","author":"Pan","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib66","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41556-018-0242-9","article-title":"Intergenerational and transgenerational epigenetic inheritance in animals","volume":"21","author":"Perez","year":"2019","journal-title":"Nat. Cell Biol."},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib67","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1042\/BJ20100174","article-title":"HDHD1, which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5\u2032-phosphatase","volume":"431","author":"Preumont","year":"2010","journal-title":"Biochem J."},{"key":"10.1016\/j.neuro.2023.05.004_bib68","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1056\/NEJMra050541","article-title":"Antiinflammatory Action of Glucocorticoids\u2014New Mechanisms for Old Drugs","volume":"353","author":"Rhen","year":"2005","journal-title":"N. Engl. J. Med"},{"issue":"1","key":"10.1016\/j.neuro.2023.05.004_bib69","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12940-021-00732-z","article-title":"Maternal methylmercury exposure through rice ingestion and child neurodevelopment in the first three years: a prospective cohort study in rural China","volume":"20","author":"Rothenberg","year":"2021","journal-title":"Environ. Health"},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib70","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.toxlet.2013.07.014","article-title":"Methylmercury exposure increases lipocalin related (lpr) and decreases activated in blocked unfolded protein response (abu) genes and specific miRNAs in Caenorhabditis elegans","volume":"222","author":"Rudgalvyte","year":"2013","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.neuro.2023.05.004_bib71","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.cbpc.2016.10.001","article-title":"Chronic MeHg exposure modifies the histone H3K4me3 epigenetic landscape in Caenorhabditis elegans","volume":"191","author":"Rudgalvyte","year":"2017","journal-title":"Comp. Biochem Physiol. C. Toxicol. Pharm."},{"issue":"6","key":"10.1016\/j.neuro.2023.05.004_bib72","doi-asserted-by":"crossref","first-page":"885","DOI":"10.2217\/epi.15.54","article-title":"Altered miRNA expression in the cervix during pregnancy associated with lead and mercury exposure","volume":"7","author":"Sanders","year":"2015","journal-title":"Epigenomics"},{"issue":"2","key":"10.1016\/j.neuro.2023.05.004_bib73","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1093\/ajcn\/nqaa338","article-title":"Associations of prenatal methylmercury exposure and maternal polyunsaturated fatty acid status with neurodevelopmental outcomes at 7 years of age: results from the Seychelles Child Development Study Nutrition Cohort 2","volume":"113","author":"Strain","year":"2021","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.neuro.2023.05.004_bib74","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.envint.2016.03.029","article-title":"Prenatal methylmercury exposure and language delay at three years of age in the Norwegian Mother and Child Cohort Study","volume":"92\u201393","author":"Vejrup","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.neuro.2023.05.004_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2022.115952","article-title":"Resveratrol attenuates methylmercury-induced neurotoxicity by modulating synaptic homeostasis","volume":"440","author":"Wang","year":"2022","journal-title":"Toxicol. Appl. Pharm."},{"issue":"12","key":"10.1016\/j.neuro.2023.05.004_bib76","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.3390\/ijms17122058","article-title":"Low-dose methylmercury-induced genes regulate mitochondrial biogenesis via miR-25 in immortalized human embryonic neural progenitor cells","volume":"17","author":"Wang","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuro.2023.05.004_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.147621","article-title":"Gestational blood levels of toxic metal and essential element mixtures and associations with global DNA methylation in pregnant women and their infants","volume":"787","author":"Weyde","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.neuro.2023.05.004_bib78","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ntt.2016.10.011","article-title":"Methyl mercury exposure and neurodevelopmental outcomes in the Seychelles Child Development Study Main cohort at age 22 and 24 years","volume":"59","author":"van Wijngaarden","year":"2017","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.neuro.2023.05.004_bib79","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/s41581-021-00415-5","article-title":"Key metalloproteinase-mediated pathways in the kidney","volume":"17","author":"Wozniak","year":"2021","journal-title":"Nat. Rev. Nephrol."},{"issue":"18","key":"10.1016\/j.neuro.2023.05.004_bib80","doi-asserted-by":"crossref","first-page":"12493","DOI":"10.1021\/acs.est.1c01771","article-title":"Compound-specific stable isotope analysis provides new insights for tracking human monomethylmercury exposure sources","volume":"55","author":"Yang","year":"2021","journal-title":"Environ. Sci. Technol."}],"container-title":["NeuroToxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X23000645?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X23000645?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T14:26:56Z","timestamp":1758983216000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161813X23000645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":80,"alternative-id":["S0161813X23000645"],"URL":"https:\/\/doi.org\/10.1016\/j.neuro.2023.05.004","relation":{},"ISSN":["0161-813X"],"issn-type":[{"value":"0161-813X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epigenetics of methylmercury","name":"articletitle","label":"Article Title"},{"value":"NeuroToxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuro.2023.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}