{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:08:16Z","timestamp":1775092096823,"version":"3.50.1"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroToxicology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.neuro.2024.11.004","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T23:12:46Z","timestamp":1732662766000},"page":"323-333","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["New insight into the molecular etiopathogenesis of konzo: Cyanate could be a plausible neurotoxin contributing to konzo, contrary to thiocyanate"],"prefix":"10.1016","volume":"105","author":[{"given":"Marius","family":"Baguma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofie","family":"Kessels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginie","family":"Bito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bert","family":"Br\u00f4ne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Triller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phanie","family":"Maynard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Legendre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Michel","family":"Rigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herv\u00e9","family":"Le Corronc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joelle Nsimire","family":"Chabwine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuro.2024.11.004_bib1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s11011-011-9237-y","article-title":"Neurological disorders associated with cassava diet: a review of putative etiological mechanisms","volume":"26","author":"Adamolekun","year":"2011","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.neuro.2024.11.004_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e19939","article-title":"Cassava production in africa: a panel analysis of the drivers and trends","volume":"9","author":"Adebayo","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.neuro.2024.11.004_bib3","doi-asserted-by":"crossref","first-page":"354","DOI":"10.7831\/ras.8.0_354","article-title":"Superior plants with significant amounts of cyanide and their toxicological implications","volume":"8","author":"Aranguri-llerena","year":"2020","journal-title":"Rev. Agric. Sci."},{"key":"10.1016\/j.neuro.2024.11.004_bib4","doi-asserted-by":"crossref","first-page":"36508","DOI":"10.1039\/C9RA05875C","article-title":"Physicochemical characterization of carbamylated human serum albumin: an in vitro study","volume":"9","author":"Badar","year":"2019","journal-title":"RSC Adv."},{"key":"10.1016\/j.neuro.2024.11.004_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/nu13082628","article-title":"Revisiting Konzo risk factors in three areas differently affected by spastic paraparesis in eastern democratic republic of the Congo discloses a prominent role of the nutritional status\u2014a comparative cross-sectional study","volume":"13","author":"Baguma","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.neuro.2024.11.004_bib6","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3390\/pr10020337","article-title":"Impact of seasonal variation and processing methods on the Cassava-derived dietary cyanide poisoning, nutritional status, and Konzo appearance in South-Kivu, Eastern D.R. Congo","volume":"10","author":"Baguma","year":"2022","journal-title":"Processes"},{"key":"10.1016\/j.neuro.2024.11.004_bib7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.neuro.2021.05.001","article-title":"Konzo risk factors, determinants and etiopathogenesis: what is new? A systematic review","volume":"85","author":"Baguma","year":"2021","journal-title":"Neurotoxicology"},{"issue":"1920","key":"10.1016\/j.neuro.2024.11.004_bib8","first-page":"295","article-title":"High prevalence of konzo associated with a food shortage crisis in the Bandundu region of zaire","volume":"72","author":"Banea","year":"1992","journal-title":"Ann. Soc. Belg. Med. Trop."},{"key":"10.1016\/j.neuro.2024.11.004_bib9","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1046\/j.1365-3156.1997.d01-215.x","article-title":"Geographical and seasonal association between linamarin and cyanide exposure from cassava and the upper motor neurone disease konzo in former Zaire","volume":"2","author":"Banea","year":"1997","journal-title":"Trop. Med. Int. Health"},{"key":"10.1016\/j.neuro.2024.11.004_bib10","doi-asserted-by":"crossref","first-page":"5371","DOI":"10.1038\/s41467-021-25694-1","article-title":"The gut microbiome in konzo","volume":"12","author":"Bramble","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neuro.2024.11.004_bib11","doi-asserted-by":"crossref","first-page":"3572","DOI":"10.3390\/su2113572","article-title":"Cassava: the drought, war and famine crop in a changing world","volume":"2","author":"Burns","year":"2010","journal-title":"Sustainability"},{"key":"10.1016\/j.neuro.2024.11.004_bib12","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/09637480410001725265","article-title":"Combination of cassava flour cyanide and urinary thiocyanate measurements of school children in Mozambique","volume":"55","author":"Cardoso","year":"2004","journal-title":"Int. J. Food Sci. Nutr."},{"key":"10.1016\/j.neuro.2024.11.004_bib13","doi-asserted-by":"crossref","first-page":"695","DOI":"10.3109\/10715762.2014.1003372","article-title":"Biochemical mechanisms and therapeutic potential of pseudohalide thiocyanate in human health","volume":"49","author":"Chandler","year":"2015","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.neuro.2024.11.004_bib14","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1111\/bph.12206","article-title":"Nebulized thiocyanate improves lung infection","volume":"169","author":"Chandler","year":"2013","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuro.2024.11.004_bib15","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1051\/ata\/2000019","article-title":"Cyanures et thiocyanates en toxicologie hospitali\u00e8re","volume":"12","author":"Charlier","year":"2000","journal-title":"Ann. Toxicol. Anal."},{"key":"10.1016\/j.neuro.2024.11.004_bib16","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S0140-6736(85)90742-1","article-title":"Association of high cyanide and low sulphur intake in cassava-induced spastic paraparesis","volume":"2","author":"Cliff","year":"1985","journal-title":"Lancet"},{"key":"10.1016\/j.neuro.2024.11.004_bib17","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ajem.2009.09.014","article-title":"Acute cyanide poisoning among jewelry and textile industry workers","volume":"29","author":"Coentr\u00e3o","year":"2011","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.neuro.2024.11.004_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0129436","article-title":"Cassava intake and vitamin A status among women and preschool children in Akwa-Ibom, Nigeria","volume":"10","author":"De Moura","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.neuro.2024.11.004_bib19","article-title":"Cyanides and their toxicity: a literature review","volume":"105","author":"Egekeze","year":"1980","journal-title":"Tijdschr. Diergeneeskd."},{"key":"10.1016\/j.neuro.2024.11.004_bib20","unstructured":"Food and Agriculture Organization of the United Nations, 2017. FAOSTAT [WWW Document]. FAOSTAT. URL \u3008http:\/\/www.fao.org\/faostat\/en\/#data\u3009 (accessed 11.22.19)."},{"key":"10.1016\/j.neuro.2024.11.004_bib21","doi-asserted-by":"crossref","first-page":"4798","DOI":"10.1038\/sj.onc.1209608","article-title":"Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy","volume":"25","author":"Fulda","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.neuro.2024.11.004_bib22","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-92142-x","article-title":"Oral pre-treatment with thiocyanate (SCN\u2212) protects against myocardial ischaemia\u2013reperfusion injury in rats","volume":"11","author":"Hall","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuro.2024.11.004_bib23","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1002\/mus.10186","article-title":"Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis","volume":"26","author":"Heath","year":"2002","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.neuro.2024.11.004_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s10741-007-9017-2","article-title":"Vasodilators in acute heart failure","volume":"12","author":"Hollenberg","year":"2007","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.neuro.2024.11.004_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24183231","article-title":"Cyanate induces oxidative stress injury and abnormal lipid metabolism in liver through Nrf2\/HO-1","volume":"24","author":"Hu","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.neuro.2024.11.004_bib26","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.neuro.2016.05.016","article-title":"Lower sulfurtransferase detoxification rates of cyanide in konzo\u2014A tropical spastic paralysis linked to cassava cyanogenic poisoning","volume":"59","author":"Kambale","year":"2017","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neuro.2024.11.004_bib27","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0928-4680(00)00053-5","article-title":"Oxidative stress and apoptosis","volume":"7","author":"Kannan","year":"2000","journal-title":"Pathophysiology"},{"key":"10.1016\/j.neuro.2024.11.004_bib28","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.fct.2010.05.080","article-title":"On the biomarkers and mechanisms of konzo, a distinct upper motor neuron disease associated with food (cassava) cyanogenic exposure","volume":"49","author":"Kassa","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.neuro.2024.11.004_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2193-1801-2-647","article-title":"Carbamoylation correlates of cyanate neuropathy and cyanide poisoning: relevance to the biomarkers of cassava cyanogenesis and motor system toxicity","volume":"2","author":"Kimani","year":"2013","journal-title":"Springerplus"},{"key":"10.1016\/j.neuro.2024.11.004_bib30","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1615\/CritRevNeurobiol.v17.i1.20","article-title":"On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies","volume":"17","author":"LePage","year":"2005","journal-title":"Crit. Rev. Neurobiol."},{"key":"10.1016\/j.neuro.2024.11.004_bib31","first-page":"111","article-title":"Reduction of MTT to purple formazan by vitamin E isomers in the absence of cells","volume":"26","author":"Lim","year":"2015","journal-title":"Trop. life Sci. Res."},{"key":"10.1016\/j.neuro.2024.11.004_bib32","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0022-510X(96)00122-0","article-title":"Toxic models of upper motor neuron disease","volume":"139","author":"Ludolph","year":"1996","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.neuro.2024.11.004_bib33","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.74441","article-title":"Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses","volume":"10","author":"Maynard","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.neuro.2024.11.004_bib34","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1541-4337.2008.00064.x","article-title":"Processing techniques to reduce toxicity and antinutrients of Cassava for use as a staple food","volume":"8","author":"Montagnac","year":"2009","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.neuro.2024.11.004_bib35","doi-asserted-by":"crossref","first-page":"743","DOI":"10.3109\/10715762.2015.1019347","article-title":"Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase","volume":"49","author":"Morgan","year":"2015","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.neuro.2024.11.004_bib36","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.fct.2010.10.035","article-title":"Strategies for elimination of cyanogens from cassava for reducing toxicity and improving food safety","volume":"49","author":"Nambisan","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.neuro.2024.11.004_bib37","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.3109\/10715762.2014.947286","article-title":"High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a fi rst myocardial infarction","volume":"48","author":"Nedoboy","year":"2014","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.neuro.2024.11.004_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001759","article-title":"Research on motor neuron diseases konzo and neurolathyrism: trends from 1990 to 2010","volume":"6","author":"Ngudi","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.neuro.2024.11.004_bib39","article-title":"Influence of cultivars and processing methods on the cyanide contents of cassava ( Manihot esculenta Crantz) and its traditional food products","volume":"5","author":"Njankouo","year":"2019","journal-title":"Sci. Afr."},{"key":"10.1016\/j.neuro.2024.11.004_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001051","article-title":"Konzo: from poverty, cassava, and cyanogen intake to toxico-nutritional neurological disease","volume":"5","author":"Nzwalo","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.neuro.2024.11.004_bib41","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/ana.24334","article-title":"Cyclical konzo epidemics and climate variability","volume":"77","author":"Oluwole","year":"2015","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuro.2024.11.004_bib42","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.3109\/09637486.2013.825697","article-title":"Normative concentrations of urine thiocyanate in cassava eating communities in Nigeria","volume":"64","author":"Oluwole","year":"2013","journal-title":"Int. J. Food Sci. Nutr."},{"key":"10.1016\/j.neuro.2024.11.004_bib43","series-title":"Cardiac Intensive Care","article-title":"Hypertensive Emergencies","author":"Pimenta","year":"2010"},{"key":"10.1016\/j.neuro.2024.11.004_bib44","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/j.1471-4159.1989.tb11762.x","article-title":"\u03b2-N-oxalylamino-L-alanine action on glutamate receptors","volume":"53","author":"Ross","year":"1989","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neuro.2024.11.004_bib45","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1146\/annurev-arplant-042110-103751","article-title":"The BioCassava plus program: biofortification of cassava for sub-Saharan Africa","volume":"62","author":"Sayre","year":"2011","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.neuro.2024.11.004_bib46","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2165\/00003088-198409030-00005","article-title":"Clinical pharmacokinetics of nitroprusside, cyanide, thiosulphate and thiocyanate","volume":"9","author":"Schulz","year":"1984","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.neuro.2024.11.004_bib47","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1097-2765(02)00482-3","article-title":"Mechanisms of caspase activation and inhibition during apoptosis","volume":"9","author":"Shi","year":"2002","journal-title":"Mol. Cell"},{"key":"10.1016\/j.neuro.2024.11.004_bib48","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.3181\/00379727-142-37171","article-title":"Cyanate and thiocyanate: acute toxicity","volume":"142","author":"Smith","year":"1973","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.neuro.2024.11.004_bib49","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s12640-013-9395-2","article-title":"The effect of lipoic acid on cyanate toxicity in different structures of the rat brain","volume":"24","author":"Soko\u0142owska","year":"2013","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.neuro.2024.11.004_bib50","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1081\/DMR-100101936","article-title":"Food toxins, ampa receptors, and motor neuron diseases","volume":"31","author":"Spencer","year":"1999","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.neuro.2024.11.004_bib51","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.neuro.2012.02.015","article-title":"Interrelationships of undernutrition and neurotoxicity: food for thought and research attention","volume":"33","author":"Spencer","year":"2012","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neuro.2024.11.004_bib52","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S1097-2765(00)80095-7","article-title":"Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization","volume":"1","author":"Srinivasula","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/j.neuro.2024.11.004_bib53","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1177\/156482650202300418","article-title":"Chronic poisoning by hydrogen cyanide in cassava and its prevention in Africa and Latin America","volume":"23","author":"Teles","year":"2002","journal-title":"Food Nutr. Bull."},{"key":"10.1016\/j.neuro.2024.11.004_bib54","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1093\/toxsci\/50.2.228","article-title":"Bioactivation of cyanide to cyanate in sulfur amino acid deficiency: relevance to neurological disease in humans subsisting on cassava","volume":"50","author":"Tor-Agbidye","year":"1999","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.neuro.2024.11.004_bib55","first-page":"361","article-title":"Toxic disorders of the upper motor neuron system","author":"Tshala-katumbay","year":"2007","journal-title":": Handb. Clin. Neurol."},{"key":"10.1016\/j.neuro.2024.11.004_bib56","first-page":"581","article-title":"Epidemiological evidence from Zaire for a dietary etiology of konzo, an upper motor neuron disease","volume":"69","author":"Tylleskar","year":"1991","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.neuro.2024.11.004_bib57","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/0140-6736(92)90006-O","article-title":"Cassava cyanogens and konzo, an upper motoneuron disease found in Africa","volume":"339","author":"Tylleskar","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.neuro.2024.11.004_bib58","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/01.jnen.0000171647.09589.07","article-title":"GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis","volume":"64","author":"Van Damme","year":"2005","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neuro.2024.11.004_bib59","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000089620","article-title":"Excitotoxicity and amyotrophic lateral sclerosis","volume":"2","author":"Van Damme","year":"2005","journal-title":"Neurodegener. Dis."},{"key":"10.1016\/j.neuro.2024.11.004_bib60","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/WNR.0b013e3283433027","article-title":"L-\u03b2-N-oxalyl-\u03b1,\u03b2-diaminopropionic acid toxicity in motor neurons","volume":"22","author":"Van Moorhem","year":"2011","journal-title":"Neuroreport"},{"key":"10.1016\/j.neuro.2024.11.004_bib61","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.fct.2010.03.054","article-title":"Unraveling the mechanism of \u03b2-N-oxalyl-\u03b1,\u03b2-diaminopropionic acid (\u03b2-ODAP) induced excitotoxicity and oxidative stress, relevance for neurolathyrism prevention","volume":"49","author":"Van Moorhem","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.neuro.2024.11.004_bib62","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/B978-0-12-391860-4.00019-7","article-title":"Polymeric nanoparticles for the selective therapy of inflammatory bowel disease","volume":"508","author":"Wachsmann","year":"2012","journal-title":"Methods Enzym."},{"key":"10.1016\/j.neuro.2024.11.004_bib63","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.toxicon.2015.05.003","article-title":"Tetrodotoxin abruptly blocks excitatory neurotransmission in mammalian CNS","volume":"103","author":"Wakita","year":"2015","journal-title":"Toxicon"},{"key":"10.1016\/j.neuro.2024.11.004_bib64","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1007\/s10495-010-0481-0","article-title":"Molecular and cellular mechanisms of excitotoxic neuronal death","volume":"15","author":"Wang","year":"2010","journal-title":"Apoptosis"},{"key":"10.1016\/j.neuro.2024.11.004_bib65","first-page":"225","article-title":"Konzo - a distinct type of upper motoneuron disease","volume":"71","author":"World Health Organization","year":"1996","journal-title":"Wkly. Epidemiol. Rec."},{"key":"10.1016\/j.neuro.2024.11.004_bib66","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s13024-017-0149-0","article-title":"The SH-SY5Y cell line in Parkinson\u2019s disease research: a systematic review","volume":"12","author":"Xicoy","year":"2017","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.neuro.2024.11.004_bib67","doi-asserted-by":"crossref","DOI":"10.1590\/0102-311x00073416","article-title":"Occupational exposure to hydrogen cyanide during large-scale cassava processing, in Alagoas State, Brazil","volume":"33","author":"Zacarias","year":"2017","journal-title":"Cad. Saude Publica"},{"key":"10.1016\/j.neuro.2024.11.004_bib68","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214476","article-title":"Sodium thiocyanate treatment attenuates atherosclerotic plaque formation and improves endothelial regeneration in mice","volume":"14","author":"Zietzer","year":"2019","journal-title":"PLoS One"}],"container-title":["NeuroToxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X24001360?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161813X24001360?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T10:45:01Z","timestamp":1734000301000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161813X24001360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":68,"alternative-id":["S0161813X24001360"],"URL":"https:\/\/doi.org\/10.1016\/j.neuro.2024.11.004","relation":{},"ISSN":["0161-813X"],"issn-type":[{"value":"0161-813X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"New insight into the molecular etiopathogenesis of konzo: Cyanate could be a plausible neurotoxin contributing to konzo, contrary to thiocyanate","name":"articletitle","label":"Article Title"},{"value":"NeuroToxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuro.2024.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}