{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T21:22:18Z","timestamp":1773868938479,"version":"3.50.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurobiology of Aging"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1016\/j.neurobiolaging.2008.01.013","type":"journal-article","created":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T11:31:50Z","timestamp":1205407910000},"page":"1834-1841","source":"Crossref","is-referenced-by-count":38,"title":["The diagnostic efficiency of biomarkers in sporadic Creutzfeldt-Jakob disease compared to Alzheimer's disease"],"prefix":"10.1016","volume":"30","author":[{"given":"Justyna Maria Czarna","family":"Bahl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niels H.H.","family":"Heegaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Falkenhorst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Laursen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"H\u00f8genhaven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u00e5re","family":"M\u00f8lbak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathrine","family":"Jespersgaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lotte","family":"Hougs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunhild","family":"Waldemar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Johannsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Christiansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib1","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1212\/WNL.57.4.728","article-title":"Quantitation of 14-3-3 and neuron-specific enolase proteins in CSF in Creutzfeldt-Jakob disease","volume":"57","author":"Aksamit","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib2","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/15622970310029912","article-title":"CSF markers for Alzheimer's disease: total tau, phospho-tau and Abeta 42","volume":"4","author":"Andreasen","year":"2003","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1159\/000017095","article-title":"14-3-3 protein, neuron-specific enolase, and S-100 protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease","volume":"10","author":"Beaudry","year":"1999","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib4","series-title":"WHO Manual for Surveillance of Human Transmissible Spongiform Encephalopathies Including Variant Creutzfeldt-Jakob Disease","author":"Brown","year":"2003"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1471-2377-6-25","article-title":"Impact of the clinical context on the 14-3-3 test for the diagnosis of sporadic CJD","volume":"6","author":"Cuadrado-Corrales","year":"2006","journal-title":"BMC Neurol."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib6","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/archneur.60.6.813","article-title":"Challenging the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease","volume":"60","author":"Geschwind","year":"2003","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib7","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00702-003-0065-z","article-title":"Core biological marker candidates of Alzheimer's disease\u2014perspectives for diagnosis, prediction of outcome and reflection of biological activity","volume":"111","author":"Hampel","year":"2004","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0304-3940(00)01697-9","article-title":"Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke","volume":"297","author":"Hesse","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib9","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3233\/JAD-2000-23-402","article-title":"Cerebrospinal fluid markers for Alzheimer's disease evaluated after acute ischemic stroke","volume":"2","author":"Hesse","year":"2000","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib10","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1056\/NEJM199609263351303","article-title":"The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies","volume":"335","author":"Hsich","year":"1996","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib11","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1212\/01.WNL.0000078890.89473.ED","article-title":"14-3-3 protein in the CSF of patients with rapidly progressive dementia","volume":"61","author":"Huang","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib12","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1212\/WNL.52.8.1555","article-title":"Improved discrimination of AD patients using beta-amyloid(1\u201342) and tau levels in CSF","volume":"52","author":"Hulstaert","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib13","first-page":"1459","article-title":"Creutzfeldt-Jakob disease: comparative analysis of MR imaging sequences","volume":"27","author":"Kallenberg","year":"2006","journal-title":"Am. J. Neuroradiol."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib14","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1136\/jnnp.71.3.401","article-title":"Highly increased CSF tau protein and decreased beta-amyloid (1\u201342) in sporadic CJD: a discrimination from Alzheimer's disease?","volume":"71","author":"Kapaki","year":"2001","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib15","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1212\/01.WNL.0000136225.80445.C9","article-title":"Sporadic Creutzfeldt-Jakob disease: magnetic resonance imaging and clinical findings","volume":"63","author":"Meissner","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib16","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1212\/01.wnl.0000242732.06714.0f","article-title":"Initial CSF total tau correlates with 1-year outcome in patients with traumatic brain injury","volume":"67","author":"Ost","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib17","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0304-3940(97)00215-2","article-title":"Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease","volume":"225","author":"Otto","year":"1997","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib18","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/sj.mp.4001220","article-title":"Phospho-tau\/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt-Jakob disease from other dementias","volume":"8","author":"Riemenschneider","year":"2003","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib19","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1212\/01.wnl.0000230159.67128.00","article-title":"CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease","volume":"67","author":"Sanchez-Juan","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib20","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1093\/brain\/awh575","article-title":"MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease: a study on inter-observer agreement","volume":"128","author":"Tschampa","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib21","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s004390051096","article-title":"Molecular genetics of human prion diseases in Germany","volume":"105","author":"Windl","year":"1999","journal-title":"Hum. Genet."},{"key":"10.1016\/j.neurobiolaging.2008.01.013_bib22","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/ana.410430109","article-title":"Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease","volume":"43","author":"Zerr","year":"1998","journal-title":"Ann. Neurol."}],"container-title":["Neurobiology of Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458008000328?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458008000328?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T02:42:29Z","timestamp":1557369749000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197458008000328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":22,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["S0197458008000328"],"URL":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2008.01.013","relation":{},"ISSN":["0197-4580"],"issn-type":[{"value":"0197-4580","type":"print"}],"subject":[],"published":{"date-parts":[[2009,11]]}}}