{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:16:05Z","timestamp":1789654565748,"version":"4.0.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007428","name":"Naito Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["2006-Nanchi-Ippan-017"],"award-info":[{"award-number":["2006-Nanchi-Ippan-017"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["20023023"],"award-info":[{"award-number":["20023023"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001863","name":"New Energy and Industrial Technology Development Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001863","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Aging"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.neurobiolaging.2011.02.023","type":"journal-article","created":{"date-parts":[[2011,4,3]],"date-time":"2011-04-03T11:52:04Z","timestamp":1301831524000},"page":"1807-1815","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"title":["A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH"],"prefix":"10.1016","volume":"33","author":[{"given":"Satoshi","family":"Futakawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyomitsu","family":"Nara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Miyajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Kuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Kaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiro","family":"Shirotani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Honda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuriko","family":"Tohyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoka","family":"Hoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Hanzawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinobu","family":"Kitazume","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Imamaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsutoshi","family":"Furukawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiro","family":"Tasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Arai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuhiko","family":"Yuasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Arai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Narimatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/jnr.490240202","article-title":"Does transferrin have a special role in the nervous system?","volume":"24","author":"Espinosa de los Monteros","year":"1989","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib3","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/ncpneuro0237","article-title":"The diagnosis and treatment of idiopathic normal pressure hydrocephalus","volume":"2","author":"Gallia","year":"2006","journal-title":"Nat. Clin. Pract. Neurol"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib4","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1227\/00006123-198802000-00020","article-title":"Predictive value of temporary external lumbar drainage in normal pressure hydrocephalus","volume":"22","author":"Haan","year":"1988","journal-title":"Neurosurgery"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib5","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/0014-5793(95)00034-7","article-title":"\u201cBrain-type\u201d N-glycosylation of asialo-transferrin from human cerebrospinal fluid","volume":"359","author":"Hoffmann","year":"1995","journal-title":"FEBS Lett."},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib6","doi-asserted-by":"crossref","first-page":"222","DOI":"10.2176\/nmc.44.222","article-title":"Clinical guidelines for idiopathic normal pressure hydrocephalus","volume":"44","author":"Ishikawa","year":"2004","journal-title":"Neurol. Med. Chir. (Tokyo)"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib7","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1743-8454-5-10","article-title":"Multiplicity of cerebrospinal fluid functions: New challenges in health and disease","volume":"5","author":"Johanson","year":"2008","journal-title":"Cerebrospinal Fluids Res"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib8","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/j.bbrc.2006.08.171","article-title":"Inhibition of tumor cell-induced platelet aggregation using a novel anti-podoplanin antibody reacting with its platelet-aggregation-stimulating domain","volume":"349","author":"Kato","year":"2006","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib9","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1074\/mcp.M800308-MCP200","article-title":"Focused differential glycan analysis with the platform antibody-assisted lectin profiling for glycan-related biomarker verification","volume":"8","author":"Kuno","year":"2009","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib10","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/nmeth803","article-title":"Evanescent-field fluorescence-assisted lectin microarray: a new strategy for glycan profiling","volume":"2","author":"Kuno","year":"2005","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib11","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/oxfordjournals.jbchem.a123850","article-title":"Release of O-linked sugar chains from glycoproteins with anhydrous hydrazine and pyridylamination of the sugar chains with improved reaction conditions","volume":"112","author":"Kuraya","year":"1992","journal-title":"J. Biochem"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib12","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.cca.2007.07.002","article-title":"Screening and diagnosis of congenital disorders of glycosylation","volume":"385","author":"Marklov\u00e1","year":"2007","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib13","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib14","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1093\/oxfordjournals.jbchem.a022562","article-title":"\u03b21-4Galactosyltransferase activity of mouse brain as revealed by analysis of brain-specific complex-type N-linked sugar chains","volume":"126","author":"Nakakita","year":"1999","journal-title":"J. Biochem"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib15","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1742-4658.2009.07430.x","article-title":"A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics","volume":"277","author":"Narimatsu","year":"2010","journal-title":"FEBS J."},{"issue":"3 suppl","key":"10.1016\/j.neurobiolaging.2011.02.023_bib16","first-page":"S4","article-title":"Diagnosing idiopathic normal-pressure hydrocephalus","volume":"57","author":"Relkin","year":"2005","journal-title":"Neurosurgery"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib17","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1159\/000147479","article-title":"Sugar chains of cerebrospinal fluid transferrin as a new biological marker of Alzheimer's disease","volume":"26","author":"Taniguchi","year":"2008","journal-title":"Dement. Geriatr. Cogn. Disord"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib18","doi-asserted-by":"crossref","first-page":"9626","DOI":"10.1016\/S0021-9258(18)60576-9","article-title":"Transferrin gene expression and synthesis by cultured choroid plexus epithelial cells","volume":"264","author":"Tsutsumi","year":"1989","journal-title":"J. Biol. Chem"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib19","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1002\/pmic.200701114","article-title":"Optimization of evanescent-field fluorescence-assisted lectin microarray for high-sensitivity detection of monovalent oligosaccharides and glycoproteins","volume":"8","author":"Uchiyama","year":"2008","journal-title":"Proteomics"},{"key":"10.1016\/j.neurobiolaging.2011.02.023_bib20","first-page":"503","article-title":"The value of temporary external lumbar CSF drainage in predicting the outcome of shunting on normal pressure hydrocephalus","volume":"72","author":"Walchenbach","year":"2002","journal-title":"J. Neurol. Neurosurg. Psychiatry"}],"container-title":["Neurobiology of Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458011000571?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458011000571?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T11:19:07Z","timestamp":1759317547000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197458011000571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0197458011000571"],"URL":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2011.02.023","relation":{},"ISSN":["0197-4580"],"issn-type":[{"value":"0197-4580","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Aging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2011.02.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}