{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T17:14:51Z","timestamp":1793466891082,"version":"4.5.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Aging"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.neurobiolaging.2012.02.028","type":"journal-article","created":{"date-parts":[[2012,3,28]],"date-time":"2012-03-28T02:31:51Z","timestamp":1332901911000},"page":"610-620","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Phospholipase A2: The key to reversing long-term memory impairment in a gastropod model of aging"],"prefix":"10.1016","volume":"34","author":[{"given":"Shawn N.","family":"Watson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra M.","family":"Hermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem C.","family":"Wildering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib1","doi-asserted-by":"crossref","first-page":"560","DOI":"10.5483\/BMBRep.2008.41.8.560","article-title":"Phospholipase A(2), reactive oxygen species, and lipid peroxidation in CNS pathologies","volume":"41","author":"Adibhatla","year":"2008","journal-title":"BMB Rep."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib2","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1016\/j.neurobiolaging.2005.09.040","article-title":"Effects of age on feeding behavior and chemosensory processing in the pond snail, Lymnaea stagnalis","volume":"27","author":"Arundell","year":"2006","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib3","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nrn1809","article-title":"Neural plasticity in the ageing brain","volume":"7","author":"Burke","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib4","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.bbalip.2010.02.005","article-title":"Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease","volume":"1801","author":"Butterfield","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib5","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.1529\/biophysj.107.123984","article-title":"Specific lipids supply critical negative spontaneous curvature\u2014An essential component of native Ca2+-triggered membrane fusion","volume":"94","author":"Churchward","year":"2008","journal-title":"Biophys. J."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib6","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1016\/S0006-3495(98)74059-7","article-title":"Effect of lipid characteristics on the structure of transmembrane proteins","volume":"75","author":"Dan","year":"1998","journal-title":"Biophys. J."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib7","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1113\/jphysiol.2007.136812","article-title":"Phospholipases and fatty acid signalling in exocytosis","volume":"585","author":"Darios","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib8","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1523\/JNEUROSCI.2168-09.2010","article-title":"12-Lipoxygenase regulates hippocampal long-term potentiation by modulating L-type Ca2+ channels","volume":"30","author":"DeCostanzo","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib9","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.tins.2006.08.005","article-title":"Learning, aging and intrinsic neuronal plasticity","volume":"29","author":"Disterhoft","year":"2006","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib10","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1474-9726.2007.00297.x","article-title":"Alterations in intrinsic neuronal excitability during normal aging","volume":"6","author":"Disterhoft","year":"2007","journal-title":"Aging Cell"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib11","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1474-9726.2007.00294.x","article-title":"Oxidative stress and aberrant signaling in aging and cognitive decline","volume":"6","author":"Dr\u00f6ge","year":"2007","journal-title":"Aging Cell"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib12","doi-asserted-by":"crossref","first-page":"11427","DOI":"10.1523\/JNEUROSCI.23-36-11427.2003","article-title":"12-lipoxygenase metabolites of arachidonic acid mediate metabotropic glutamate receptor-dependent long-term depression at hippocampal CA3-CA1 synapses","volume":"23","author":"Feinmark","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib13","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1186\/1471-2164-10-451","article-title":"Transcriptome analysis of the central nervous system of the mollusc Lymnaea stagnalis","volume":"10","author":"Feng","year":"2009","journal-title":"BMC Genomics"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib14","first-page":"1941","article-title":"Death rates reflect accumulating brain damage in arthropods","volume":"272","author":"Fonseca","year":"2005","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib15","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.1749-6632.2001.tb05646.x","article-title":"Impairment of learning and memory in rats caused by oxidative stress and aging, and changes in antioxidative defense systems","volume":"928","author":"Fukui","year":"2001","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib16","doi-asserted-by":"crossref","first-page":"re1","DOI":"10.1126\/sageke.2005.5.re1","article-title":"Lipofuscin and aging: a matter of toxic waste","volume":"2005","author":"Gray","year":"2005","journal-title":"Sci. Aging Knowledge Environ."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib17","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1093\/geronj\/11.3.298","article-title":"Aging: a theory based on free radical and radiation chemistry","volume":"11","author":"Harman","year":"1956","journal-title":"J. Gerontol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib18","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1146\/annurev.physiol.010908.163149","article-title":"Endocannabinoid signaling and long-term synaptic plasticity","volume":"71","author":"Heifets","year":"2009","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib19","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF02577689","article-title":"Pronase modifies synaptic transmission and activity of identified Lymnaea neurons","volume":"3","author":"Hermann","year":"1998","journal-title":"Invert. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib20","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1037\/0735-7044.121.6.1400","article-title":"Impairment of long-term associative memory in aging snails (Lymnaea stagnalis)","volume":"121","author":"Hermann","year":"2007","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib21","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1749-6632.2009.05372.x","article-title":"Age-related behavioral changes in Drosophila","volume":"1197","author":"Iliadi","year":"2010","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib22","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0047-6374(88)90052-8","article-title":"Survival characteristics of the mollusc Lymnaea stagnalis under constant culture conditions: effects of aging and disease","volume":"42","author":"Janse","year":"1988","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib23","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1101\/lm.1365609","article-title":"Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice","volume":"16","author":"Kaczorowski","year":"2009","journal-title":"Learn. Mem."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib24","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/nm.f.1869","article-title":"Endocannabinoid signaling as a synaptic circuit breaker in neurological disease","volume":"14","author":"Katona","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib25","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0197-4580(98)00065-7","article-title":"Multiple synaptic connections of a single neuron change differentially with age","volume":"19","author":"Klaassen","year":"1998","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib26","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1111\/j.1471-4159.2010.07033.x","article-title":"Phospholipases A2 and neural membrane dynamics: implications for Alzheimer's disease","volume":"116","author":"Lee","year":"2011","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib27","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1111\/j.1460-9568.2007.05945.x","article-title":"Cannabinoid regulation in identified synapse of terrestrial snail","volume":"26","author":"Lemak","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0014-5793(00)01388-0","article-title":"Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel","volume":"471","author":"Lesage","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib29","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0009-3084(99)00101-2","article-title":"Antioxidative and prooxidative effects of coumarin derivatives on free radical initiated and photosensitized peroxidation of human low-density lipoprotein","volume":"103","author":"Liu","year":"1999","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib30","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/sj.bjp.0702069","article-title":"Actions of general anaesthetics and arachidonic pathway inhibitors on K+ currents activated by volatile anaesthetics and FMRFamide in molluscan neurones","volume":"125","author":"Lopes","year":"1998","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib31","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1111\/j.1532-5415.2010.03066.x","article-title":"Mild Cognitive Impairment: Incidence and Risk Factors: Results of the Leipzig Longitudinal Study of the Aged","volume":"58","author":"Luck","year":"2010","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib32","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1242\/jeb.201.6.877","article-title":"Long-term memory of an operantly conditioned respiratory behaviour pattern in Lymnaea stagnalis","volume":"201","author":"Lukowiak","year":"1998","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib33","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1242\/jeb.199.3.683","article-title":"Operant conditioning of aerial respiratory behaviour in Lymnaea stagnalis","volume":"199","author":"Lukowiak","year":"1996","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib34","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.chemphyslip.2003.10.010","article-title":"Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases","volume":"128","author":"Montine","year":"2004","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib35","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/j.cell.2006.09.052","article-title":"Neuronal transcriptome of Aplysia: neuronal compartments and circuitry","volume":"127","author":"Moroz","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib36","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.freeradbiomed.2005.08.044","article-title":"Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia","volume":"40","author":"Muralikrishna Adibhatla","year":"2006","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib37","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1152\/jn.2001.85.4.1639","article-title":"Receptor-stimulated phospholipase A(2) liberates arachidonic acid and regulates neuronal excitability through protein kinase C","volume":"85","author":"Muzzio","year":"2001","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib38","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/0076-6879(90)86095-D","article-title":"Free radical initiators as source of water- or lipid-soluble peroxyl radicals","volume":"186","author":"Niki","year":"1990","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib39","first-page":"2","article-title":"Learning and aging related changes in intrinsic neuronal excitability","volume":"2","author":"Oh","year":"2010","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib40","doi-asserted-by":"crossref","first-page":"446","DOI":"10.3758\/BF03200814","article-title":"EthoLog 2.2: a tool for the transcription and timing of behavior observation sessions","volume":"32","author":"Ottoni","year":"2000","journal-title":"Behav. Res. Methods Instrum. Comput."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib41","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1242\/jeb.01545","article-title":"Boosting intermediate-term into long-term memory","volume":"208","author":"Parvez","year":"2005","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib42","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1016\/j.neurobiolaging.2005.09.041","article-title":"Changes in the properties of the modulatory cerebral giant cells contribute to aging in the feeding system of Lymnaea","volume":"27","author":"Patel","year":"2006","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib43","first-page":"65","article-title":"Eicosanoids in synaptic transmission","volume":"8","author":"Piomelli","year":"1994","journal-title":"Crit. Rev. Neurobiol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib44","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/328038a0","article-title":"Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells","volume":"328","author":"Piomelli","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib45","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1016\/S0014-2999(99)00496-3","article-title":"Enhancement of memory in cannabinoid CB1 receptor knock-out mice","volume":"379","author":"Reibaud","year":"1999","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib46","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0076-6879(94)34095-1","article-title":"Total antioxidant status in plasma and body fluids","volume":"234","author":"Rice-Evans","year":"1994","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib47","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1006\/abio.1995.1410","article-title":"Continuous measurement of phospholipase A2 activity using the fluorescent probe ADIFAB","volume":"229","author":"Richieri","year":"1995","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib48","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1023\/A:1006878421990","article-title":"The measurement of free fatty acid concentration with the fluorescent probe ADIFAB: a practical guide for the use of the ADIFAB probe","volume":"192","author":"Richieri","year":"1999","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib49","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1196\/annals.1300.013","article-title":"Exogenous and endogenous cannabinoids control synaptic transmission in mice nucleus accumbens","volume":"1003","author":"Robbe","year":"2003","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib50","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.chemphyslip.2003.09.016","article-title":"The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation","volume":"128","author":"Roberts","year":"2004","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib51","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.bbalip.2010.05.013","article-title":"Phospholipase A2 and arachidonic acid in Alzheimer's disease","volume":"1801","author":"Sanchez-Mejia","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib52","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1038\/nn.2213","article-title":"Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease","volume":"11","author":"Sanchez-Mejia","year":"2008","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib53","doi-asserted-by":"crossref","first-page":"8034","DOI":"10.1523\/JNEUROSCI.23-22-08034.2003","article-title":"Reconsolidation of a long-term memory in Lymnaea requires new protein and RNA synthesis and the soma of right pedal dorsal 1","volume":"23","author":"Sangha","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib54","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/0-387-27023-X_47","article-title":"Memory, reconsolidation and extinction in Lymnaea require the soma of RPeD1","volume":"551","author":"Sangha","year":"2004","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib55","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1152\/jn.2002.88.4.1584","article-title":"The Soma of RPeD1 must be present for long-term memory formation of associative learning in Lymnaea","volume":"88","author":"Scheibenstock","year":"2002","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib56","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1021\/bi061853s","article-title":"The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation","volume":"46","author":"Siegel","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib57","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0047-6374(88)90053-X","article-title":"A quantitative method to evaluate the quality of interrupted animal cultures in aging studies","volume":"42","author":"Slob","year":"1988","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib58","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1152\/jn.2002.88.4.1915","article-title":"Changes in the activity of a CpG neuron after the reinforcement of an operantly conditioned behavior in Lymnaea","volume":"88","author":"Spencer","year":"2002","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib59","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1089\/rej.2009.0934","article-title":"Is lipid peroxidation of polyunsaturated acids the only source of free radicals that induce aging and age-related diseases?","volume":"13","author":"Spiteller","year":"2010","journal-title":"Rejuvenation Res."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib60","doi-asserted-by":"crossref","first-page":"341","DOI":"10.3233\/JAD-2010-1222","article-title":"Role of oxidative stress in the progression of Alzheimer's disease","volume":"19","author":"Sultana","year":"2010","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib61","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1042\/bj20040031","article-title":"Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D","volume":"380","author":"Sun","year":"2004","journal-title":"Biochem. J."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib62","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1242\/jeb.158.1.37","article-title":"Coordination of locomotor and cardiorespiratory networks of Lymnaea stagnalis by a pair of identified interneurones","volume":"158","author":"Syed","year":"1991","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib63","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1179\/135100001101535996","article-title":"Garbage catastrophe theory of aging: imperfect removal of oxidative damage?","volume":"6","author":"Terman","year":"2001","journal-title":"Redox Rep."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib64","first-page":"727","article-title":"Direct opening of S-type K+ channels of Aplysia sensory neurons by 12-lipoxygenase metabolites","volume":"21B","author":"Volterra","year":"1991","journal-title":"Adv. Prostaglandin Thromboxane Leukot. Res."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib65","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.neurobiolaging.2010.01.017","article-title":"Redox agents modulate neuronal activity and reproduce physiological aspects of neuronal aging","volume":"33","author":"Watson","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib66","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.1523\/JNEUROSCI.5205-03.2004","article-title":"Cognitive aging and the hippocampus: how old rats represent new environments","volume":"24","author":"Wilson","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2012.02.028_bib67","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1568-1637(01)00009-5","article-title":"Age-related biophysical alterations of hippocampal pyramidal neurons: implications for learning and memory","volume":"1","author":"Wu","year":"2002","journal-title":"Ageing Res. Rev."}],"container-title":["Neurobiology of Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458012001777?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458012001777?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T11:22:34Z","timestamp":1759317754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197458012001777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S0197458012001777"],"URL":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2012.02.028","relation":{},"ISSN":["0197-4580"],"issn-type":[{"value":"0197-4580","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phospholipase A2: The key to reversing long-term memory impairment in a gastropod model of aging","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Aging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2012.02.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}