{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:59:26Z","timestamp":1790171966072,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","neurobiologyofaging.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Aging"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.neurobiolaging.2014.08.020","type":"journal-article","created":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T14:16:46Z","timestamp":1409149006000},"page":"547.e13-547.e16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["C9ORF72 hexanucleotide repeat expansions are a frequent cause of Huntington disease phenocopies in the Greek population"],"prefix":"10.1016","volume":"36","author":[{"given":"Georgios","family":"Koutsis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Karadima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrisoula","family":"Kartanou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athina","family":"Kladi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Panas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1136\/jmedgenet-2014-102360","article-title":"A\u00a0blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories","volume":"51","author":"Akimoto","year":"2014","journal-title":"J.\u00a0Med. Genet."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib2","first-page":"852","article-title":"Huntington disease without CAG expansion: phenocopies or errors in assignment?","volume":"54","author":"Andrew","year":"1994","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.ajhg.2013.01.011","article-title":"Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population","volume":"92","author":"Beck","year":"2013","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib4","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/brain\/aws004","article-title":"Characterization of frontotemporal dementia and\/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72","volume":"135","author":"Boeve","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib5","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.neuron.2011.09.011","article-title":"Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS","volume":"72","author":"DeJesus-Hernandez","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib6","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1212\/WNL.0000000000000061","article-title":"C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies","volume":"82","author":"Hensman Moss","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib7","article-title":"C9orf72 expansions as a possible genetic cause of Huntington disease phenocopy syndrome","author":"Kosti\u0107","year":"2014","journal-title":"J.\u00a0Neurol."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib8","first-page":"1874","article-title":"Genetic screening of Greek patients with Huntington\u2019s disease phenocopies identifies an SCA8 expansion","volume":"259","author":"Koutsis","year":"2012","journal-title":"J.\u00a0Neurol."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib9","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/brain\/awr361","article-title":"Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features","volume":"135","author":"Mahoney","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib10","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S1474-4422(12)70043-1","article-title":"Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study","volume":"11","author":"Majounie","year":"2012","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib11","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1136\/jnnp-2012-302532","article-title":"The differential diagnosis of Huntington's disease-like syndromes: \u2018red flags\u2019 for the clinician","volume":"84","author":"Martino","year":"2013","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib12","doi-asserted-by":"crossref","first-page":"1851.e1","DOI":"10.1016\/j.neurobiolaging.2012.02.021","article-title":"High frequency of the expanded C9ORF72 hexanucleotide repeat in familial and sporadic Greek ALS patients","volume":"33","author":"Mok","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib13","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.51.6.1546","article-title":"Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria","volume":"51","author":"Neary","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib14","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neuron.2011.09.010","article-title":"A\u00a0hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD","volume":"72","author":"Renton","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib15","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1750-1172-5-40","article-title":"Huntington's disease: a clinical review","volume":"5","author":"Roos","year":"2010","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib16","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/brain\/awr355","article-title":"Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations","volume":"135","author":"Snowden","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib17","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/mds.21915","article-title":"Huntington's disease phenocopies are clinically and genetically heterogeneous","volume":"23","author":"Wild","year":"2008","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neurobiolaging.2014.08.020_bib18","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1097\/WCO.0b013e3282f12074","article-title":"Huntington's disease phenocopy syndromes","volume":"20","author":"Wild","year":"2007","journal-title":"Curr. Opin. Neurol."}],"container-title":["Neurobiology of Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458014005338?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458014005338?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,30]],"date-time":"2018-09-30T03:57:10Z","timestamp":1538279830000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197458014005338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S0197458014005338"],"URL":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2014.08.020","relation":{},"ISSN":["0197-4580"],"issn-type":[{"value":"0197-4580","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"C9ORF72 hexanucleotide repeat expansions are a frequent cause of Huntington disease phenocopies in the Greek population","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Aging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2014.08.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}