{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:02:35Z","timestamp":1769040155393,"version":"3.49.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"gs1:Ministerio de Ciencia e Innovaci\u00f3n","award":["SAF2014-52582-R"],"award-info":[{"award-number":["SAF2014-52582-R"]}]},{"name":"Instituto de Salud Carlos III\u2013Fondos FEDER","award":["PI14\/00757"],"award-info":[{"award-number":["PI14\/00757"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Aging"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.neurobiolaging.2016.08.027","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T16:13:24Z","timestamp":1473437604000},"page":"52-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"special_numbering":"C","title":["Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by Alzheimer's and Parkinson's diseases"],"prefix":"10.1016","volume":"49","author":[{"given":"Raquel","family":"Marin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noem\u00ed","family":"Fabelo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Garcia-Esparcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isidre","family":"Ferrer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Quinto-Alemany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5692-8906","authenticated-orcid":false,"given":"Mario","family":"D\u00edaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib1","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1083\/jcb.200404149","article-title":"Neuronal membrane cholesterol loss enhances amyloid peptide generation","volume":"167","author":"Abad-Rodriguez","year":"2004","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib2","doi-asserted-by":"crossref","first-page":"10858","DOI":"10.1073\/pnas.0502903102","article-title":"Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival","volume":"102","author":"Akbar","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib3","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s00401-009-0523-2","article-title":"Staging\/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium","volume":"117","author":"Alafuzoff","year":"2009","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib4","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/nrn2059","article-title":"Lipid raft microdomains and neurotransmitter signalling","volume":"8","author":"Allen","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib5","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.neuint.2004.08.006","article-title":"Amyloid-beta deposition in the cerebral cortex in Dementia with Lewy bodies is accompanied by a relative increase in A\u03b2PP mRNA isoforms containing the Kunitz protease inhibitor","volume":"46","author":"Barrachina","year":"2005","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.molbrainres.2004.08.006","article-title":"Upregulation of amyloid precursor protein isoforms containing Kunitz protease inhibitor in dementia with Lewy bodies","volume":"131","author":"Beyer","year":"2004","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib7","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.bbalip.2003.12.010","article-title":"Functions and biosynthesis of plasmalogens in health and disease","volume":"1636","author":"Brites","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib8","doi-asserted-by":"crossref","first-page":"17221","DOI":"10.1074\/jbc.R000005200","article-title":"Structure and function of sphingolipid- and cholesterol-rich membrane rafts","volume":"275","author":"Brown","year":"2000","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib9","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.plefa.2007.10.019","article-title":"Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies","volume":"77","author":"Calon","year":"2007","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib10","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/j.1471-4159.2009.06335.x","article-title":"Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function","volume":"111","author":"Cao","year":"2009","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib11","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.bbamem.2007.11.003","article-title":"Docosahexaenoic acid alters the size and distribution of cell surface microdomains","volume":"1778","author":"Chapkin","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib12","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1021\/tx100305b","article-title":"Lysophosphatidylcholine is generated by spontaneous deacylation of oxidized phospholipids","volume":"24","author":"Choi","year":"2011","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib13","series-title":"Lipid Analysis","author":"Christie","year":"2003"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib14","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/09687860500496417","article-title":"The involvement of lipid rafts in Alzheimer\u2019s disease","volume":"23","author":"Cordy","year":"2006","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib15","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1750-3639.2004.tb00082.x","article-title":"Abnormal metabotropic glutamate receptor expression and signaling in the cerebral cortex in diffuse Lewy body disease is associated with irregular alpha-synuclein\/phospholipase C (PLC\u03b21) interactions","volume":"14","author":"Dalf\u00f3","year":"2004","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib16","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1097\/01.jnen.0000179050.54522.5a","article-title":"Evidence of oxidative stress in the neocortex in incidental Lewy body disease","volume":"64","author":"Dalf\u00f3","year":"2005","journal-title":"J.\u00a0Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib17","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.neuron.2013.05.035","article-title":"Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway","volume":"79","author":"Das","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib18","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0140-6736(86)92471-2","article-title":"Lipid peroxidation as a cause of nigral death in Parkinson\u2019s disease","volume":"2","author":"Dexter","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib19","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1471-4159.1989.tb09133.x","article-title":"Basal lipid peroxidation in substantia nigra is increased in Parkinson\u2019s disease","volume":"52","author":"Dexter","year":"1989","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib20","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/ana.410350107","article-title":"Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease","volume":"35","author":"Dexter","year":"1994","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib21","doi-asserted-by":"crossref","first-page":"454","DOI":"10.3389\/fphys.2012.00454","article-title":"Genotype-induced changes in biophysical properties of frontal cortex lipid raft from APP\/PS1 transgenic mice","volume":"3","author":"D\u00edaz","year":"2012","journal-title":"Front. Physiol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib22","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.3233\/JAD-141146","article-title":"Biophysical alterations in lipid rafts from human cerebral cortex associate with increased BACE1\/A\u03b2PP interaction in early stages of Alzheimer\u2019s disease","volume":"43","author":"D\u00edaz","year":"2015","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib23","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1016\/j.neurobiolaging.2014.02.005","article-title":"Altered lipid composition in cortical lipid rafts occurs at early stages of sporadic Alzheimer\u2019s disease and facilitates APP\/BACE1 interactions","volume":"35","author":"Fabelo","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib24","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.2119\/molmed.2011.00119","article-title":"Severe alterations in lipid composition of frontal cortex lipid rafts from Parkinson\u2019s disease and incidental Parkinson\u2019s disease","volume":"17","author":"Fabelo","year":"2011","journal-title":"Mol. Med."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib25","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.neuroscience.2014.07.079","article-title":"Ab promotes VDAC1 channel dephosphorylation in neuronal lipid rafts. Relevance to the mechanisms of neurotoxicity in Alzheimer\u2019s Disease","volume":"278","author":"Fernandez-Echevarr\u00eda","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib26","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s10863-009-9243-5","article-title":"Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer\u2019s disease","volume":"41","author":"Ferrer","year":"2009","journal-title":"J.\u00a0Bioenerg. Biomembr."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib27","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.pneurobio.2009.02.004","article-title":"Early involvement of the cerebral cortex in Parkinson\u2019s disease: convergence of multiple metabolic defects","volume":"88","author":"Ferrer","year":"2009","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib28","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1073\/pnas.86.10.3479","article-title":"Plasmenylethanolamine is the major storage depot for arachidonic acid in rabbit vascular smooth muscle and is rapidly hydrolyzed after angiotensin II stimulation","volume":"86","author":"Ford","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib29","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1002\/jnr.21904","article-title":"Increased oxidation of certain glycolysis and energy metabolism enzymes in the frontal cortex in Lewy body diseases","volume":"87","author":"G\u00f3mez","year":"2009","journal-title":"J.\u00a0Neurosci. Res."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib30","doi-asserted-by":"crossref","first-page":"11370","DOI":"10.1073\/pnas.0904835106","article-title":"Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid","volume":"106","author":"He","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib31","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0005-2736(89)90510-5","article-title":"Influence of plasmalogen deficiency on membrane fluidity of human skin fibroblasts: a fluorescence anisotropy study","volume":"978","author":"Hermetter","year":"1989","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib32","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1111\/j.1471-4159.2010.06987.x","article-title":"Voltage-dependent anion channel as a resident protein of lipid rafts: post-transductional regulation by estrogens and involvement in neuronal preservation against Alzheimer\u2019s disease","volume":"116","author":"Herrera","year":"2011","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib33","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3389\/fphys.2012.00189","article-title":"Lipid rafts and Alzheimer\u2019s disease: protein-lipid interactions and perturbation of signalling","volume":"3","author":"Hicks","year":"2012","journal-title":"Front. Physiol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib34","series-title":"Applied Discriminant Analysis","author":"Huberty","year":"1994"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib35","series-title":"Neurodegeneration, the Molecular Pathology of Dementia and Movement Disorders","first-page":"224","article-title":"Dementia with Lewy bodies and Parkinson\u2019s disease with dementia","author":"Ince","year":"2011"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib36","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1083\/jcb.200410090","article-title":"A\u00a0lipid boundary separates APP and secretases and limits amyloid beta-peptide generation","volume":"167","author":"Kaether","year":"2004","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib37","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1385\/JMN:20:2:83","article-title":"Alpha-synuclein: its biological function and role in neurodegenerative diseases","volume":"20","author":"Kaplan","year":"2003","journal-title":"J.\u00a0Mol. Neurosci."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib38","first-page":"502","article-title":"Parkinson\u2019s disease as multifactorial oxidative neurodegeneration: implications for integrative management","volume":"5","author":"Kidd","year":"2000","journal-title":"Altern. Med. Rev."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib39","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.plefa.2010.02.025","article-title":"Phosphatidylserine-dependent neuroprotective signaling promoted by docosahexaenoic acid","volume":"82","author":"Kim","year":"2010","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib40","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1523\/JNEUROSCI.4564-06.2007","article-title":"Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies","volume":"27","author":"Kramer","year":"2007","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib41","doi-asserted-by":"crossref","first-page":"31664","DOI":"10.1074\/jbc.M504894200","article-title":"A\u00a0combinatorial code for the interaction of alpha-synuclein with membranes","volume":"280","author":"Kubo","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib42","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.1172\/JCI25420","article-title":"A\u00a0role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease","volume":"115","author":"Lukiw","year":"2005","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib43","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.steroids.2007.12.007","article-title":"Modulation of Ab-induced neurotoxicity by estrogen receptor alpha and other associated proteins in lipid rafts","volume":"73","author":"Mar\u00edn","year":"2008","journal-title":"Steroids"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib44","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1080\/09687860601055559","article-title":"Voltage-dependent anion channel (VDAC) participates in amyloid beta-induced toxicity and interacts with plasma membrane estrogen receptor \u03b1 in septal and hippocampal neurons","volume":"24","author":"Mar\u00edn","year":"2007","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib45","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.jneumeth.2005.10.019","article-title":"Selective enrichment in polyunsaturated fatty acids in phospholipids from neuronal-derived cell lines","volume":"153","author":"Mart\u00edn","year":"2006","journal-title":"J.\u00a0Neurosci. Meth."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib46","doi-asserted-by":"crossref","first-page":"489","DOI":"10.3233\/JAD-2010-1242","article-title":"Lipid alterations in lipid rafts from Alzheimer\u2019s disease human brain cortex","volume":"19","author":"Mart\u00edn","year":"2010","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib48","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S1474-4422(03)00619-7","article-title":"Dementia with Lewy bodies","volume":"3","author":"McKeith","year":"2004","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib49","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.mad.2005.09.014","article-title":"Pathophysiology of synuclein aggregation in Lewy body disease","volume":"127","author":"Mukaetova-Ladinska","year":"2006","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib50","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1016\/j.febslet.2013.05.010","article-title":"The amyloid precursor protein: a biochemical enigma in brain development, function and disease","volume":"587","author":"Nalivaeva","year":"2013","journal-title":"FEBS Lett."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib51","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.bbalip.2010.02.011","article-title":"Docosahexaenoic acid and synaptic protection in Alzheimer's disease mice","volume":"1801","author":"Oster","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib52","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.bcp.2014.01.015","article-title":"Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease","volume":"88","author":"Overk","year":"2014","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib53","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1471-4159.2009.06150.x","article-title":"On the mechanism of internalization of alpha-synuclein into microglia: roles of ganglioside GM1 and lipid raft","volume":"110","author":"Park","year":"2009","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib54","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1042\/bj20031672","article-title":"Lipid rafts: heterogeneity on the high seas","volume":"378","author":"Pike","year":"2004","journal-title":"Biochem. J."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib55","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.mcn.2009.07.001","article-title":"VDAC and Er\u03b1 interaction in caveolae from human cortex is altered in Alzheimer\u2019s disease","volume":"42","author":"Ram\u00edrez","year":"2009","journal-title":"Mol. Cell Neurosci."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/369808","article-title":"Alzheimer\u2019s disease and the amyloid cascade hypothesis: a critical review","volume":"2012","author":"Reitz","year":"2012","journal-title":"Int. J. Alzheimers Dis."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib57","doi-asserted-by":"crossref","first-page":"e718","DOI":"10.1038\/tp.2015.214","article-title":"Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns","volume":"6","author":"Sanchez-Mut","year":"2016","journal-title":"Trans. Psychiatr."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib58","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.plipres.2007.12.004","article-title":"The opposing effects of n\u22123 and n\u22126 fatty acids","volume":"47","author":"Schmitz","year":"2008","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib59","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00401-010-0711-0","article-title":"The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson\u2019s disease and Parkinson\u2019s disease with Lewy bodies, Parkinson's disease and Parkinson's disease dementia","volume":"120","author":"Schulz-Schaeffer","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib60","doi-asserted-by":"crossref","first-page":"8083","DOI":"10.1523\/JNEUROSCI.1091-10.2010","article-title":"A\u00a0pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration","volume":"30","author":"Scott","year":"2010","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib61","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1529\/biophysj.104.044552","article-title":"Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study","volume":"87","author":"Shaikh","year":"2004","journal-title":"Biophys. J."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0009-3084(03)00101-4","article-title":"Docosahexaenoic acid: membrane properties of a unique fatty acid","volume":"126","author":"Stillwell","year":"2003","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib63","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.jnutbio.2009.11.003","article-title":"Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance","volume":"21","author":"Su","year":"2010","journal-title":"J.\u00a0Nutr. Biochem."},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib64","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.bbalip.2010.03.007","article-title":"Membrane rafts in Alzheimer\u2019s disease beta-amyloid production","volume":"1801","author":"Vetrivel","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib65","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1093\/brain\/awu119","article-title":"Convergence of pathology in dementia with Lewy bodies and Alzheimer\u2019s disease: a role for the novel interaction of \u03b1-synuclein and presenilin 1 in disease","volume":"137","author":"Winslow","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.neurobiolaging.2016.08.027_bib66","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0736-5748(00)00013-7","article-title":"Essential fatty acids and the brain: possible health implications","volume":"18","author":"Youdim","year":"2000","journal-title":"Int. J. Dev. Neurosci."}],"container-title":["Neurobiology of Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458016302056?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458016302056?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,6,26]],"date-time":"2018-06-26T12:36:19Z","timestamp":1530016579000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197458016302056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":65,"alternative-id":["S0197458016302056"],"URL":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2016.08.027","relation":{},"ISSN":["0197-4580"],"issn-type":[{"value":"0197-4580","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by Alzheimer's and Parkinson's diseases","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Aging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2016.08.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}