{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:28:33Z","timestamp":1759336113766,"version":"build-2065373602"},"reference-count":4,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Aging"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.neurobiolaging.2020.10.026","type":"journal-article","created":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T11:36:54Z","timestamp":1605181014000},"page":"104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Reply: MELAS can be delineated from CADASIL by genotype and phenotype"],"prefix":"10.1016","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1036-1956","authenticated-orcid":false,"given":"Nai-Yi","family":"Liao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwong-Kum","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Chu","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Chung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurobiolaging.2020.10.026_bib1","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1001\/archneur.62.7.1154","article-title":"Deep white matter pathologic features in watershed regions: a novel pattern of central nervous system involvement in MELAS","volume":"62","author":"Apostolova","year":"2005","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neurobiolaging.2020.10.026_bib2","first-page":"233","article-title":"MELAS syndrome: imaging and proton MR spectroscopic findings","volume":"1995","author":"Castillo","year":"1995","journal-title":"AJNR. Am. J. Neuroradiol."},{"key":"10.1016\/j.neurobiolaging.2020.10.026_bib3","article-title":"Mitochondrial DNA m. 3243A> G mutation rarely causes CADASIL-like phenotype","author":"Liao","year":"2020","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neurobiolaging.2020.10.026_bib4","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/ene.14183","article-title":"Monogenic cerebral small-vessel diseases: diagnosis and therapy. Consensus recommendations of the European Academy of Neurology","volume":"27","author":"Mancuso","year":"2020","journal-title":"Eur. J. Neurol."}],"container-title":["Neurobiology of Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458020303389?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197458020303389?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T11:37:09Z","timestamp":1759318629000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197458020303389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":4,"alternative-id":["S0197458020303389"],"URL":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2020.10.026","relation":{},"ISSN":["0197-4580"],"issn-type":[{"type":"print","value":"0197-4580"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reply: MELAS can be delineated from CADASIL by genotype and phenotype","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Aging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2020.10.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}