{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:18:03Z","timestamp":1791400683503,"version":"4.3.3"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,8]],"date-time":"2015-01-08T00:00:00Z","timestamp":1420675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"European Union's Seventh Framework Programme","award":["278850"],"award-info":[{"award-number":["278850"]}]},{"name":"Molecular Imaging of Brain Pathophysiology (BRAINPATH)","award":["612360"],"award-info":[{"award-number":["612360"]}]},{"name":"Institute for the Promotion of Innovation by Science and Technology (IWT)","award":["131060"],"award-info":[{"award-number":["131060"]}]},{"DOI":"10.13039\/501100007660","name":"University of Antwerp","doi-asserted-by":"crossref","award":["BOF-DOCPRO 2013"],"award-info":[{"award-number":["BOF-DOCPRO 2013"]}],"id":[{"id":"10.13039\/501100007660","id-type":"DOI","asserted-by":"crossref"}]},{"name":"FWO krediet aan navorser research","award":["1510514N"],"award-info":[{"award-number":["1510514N"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.neuroimage.2015.01.009","type":"journal-article","created":{"date-parts":[[2015,1,9]],"date-time":"2015-01-09T12:28:29Z","timestamp":1420806509000},"page":"151-159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"special_numbering":"C","title":["Acute modulation of the cholinergic system in the mouse brain detected by pharmacological resting-state functional MRI"],"prefix":"10.1016","volume":"109","author":[{"given":"Disha","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Blockx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter-Jan","family":"Guns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Paul","family":"De Deyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debby","family":"Van Dam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Jonckers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Delgado y Palacios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marleen","family":"Verhoye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemie","family":"Van der Linden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroimage.2015.01.009_bb0005","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1111\/j.1460-9568.2010.07251.x","article-title":"Hippocampal\u2013anterior thalamic pathways for memory: uncovering a network of direct and indirect actions","volume":"31","author":"Aggleton","year":"2010","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0010","doi-asserted-by":"crossref","first-page":"192","DOI":"10.4103\/0253-7613.56072","article-title":"Cholinergic influence on memory stages: a study on scopolamine amnesic mice","volume":"41","author":"Agrawal","year":"2009","journal-title":"Indian J. Pharmacol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0015","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1177\/0269881110379285","article-title":"Scopolamine disrupts hippocampal activity during allocentric spatial memory in humans: an fMRI study using a virtual reality analogue of the Morris Water Maze","volume":"25","author":"Antonova","year":"2011","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0020","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/0031-9384(72)90310-1","article-title":"Effects of epileptic foci in the visual cortex of the rat on passive avoidance learning","volume":"8","author":"Aquino-Cias","year":"1972","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0025","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0301-0082(02)00079-5","article-title":"Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies","volume":"68","author":"Auld","year":"2002","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0030","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1172\/JCI27120","article-title":"Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody","volume":"116","author":"Bales","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0035","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/mrm.1910340409","article-title":"Functional connectivity in the motor cortex of resting human brain using echo-planar MRI","volume":"34","author":"Biswal","year":"1995","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0040","doi-asserted-by":"crossref","first-page":"9166","DOI":"10.1523\/JNEUROSCI.22-21-09166.2002","article-title":"Correlations between visual recognition memory and neocortical and hippocampal glucose metabolism after bilateral rhinal cortex lesions in the baboon: implications for Alzheimer's disease","volume":"22","author":"Blaizot","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0050","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1523\/JNEUROSCI.23-02-00611.2003","article-title":"Muscarinic blockade slows and degrades the location-specific firing of hippocampal pyramidal cells","volume":"23","author":"Brazhnik","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0045","doi-asserted-by":"crossref","first-page":"9313","DOI":"10.1523\/JNEUROSCI.1618-04.2004","article-title":"The effects on place cells of local scopolamine dialysis are mimicked by a mixture of two specific muscarinic antagonists","volume":"24","author":"Brazhnik","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1440.011","article-title":"The brain's default network: anatomy, function, and relevance to disease","volume":"1124","author":"Buckner","year":"2008","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0060","doi-asserted-by":"crossref","first-page":"3826","DOI":"10.1523\/JNEUROSCI.0410-04.2004","article-title":"Corticohippocampal contributions to spatial and contextual learning","volume":"24","author":"Burwell","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0065","doi-asserted-by":"crossref","first-page":"10539","DOI":"10.1523\/JNEUROSCI.22-24-10539.2002","article-title":"Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation","volume":"22","author":"Buttini","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0070","doi-asserted-by":"crossref","first-page":"S366","DOI":"10.1038\/sj.jcbfm.9591524.0366","article-title":"Visualizing the effects of scopolamine in the rat brain using functional MRI","volume":"25","author":"Cash","year":"2005","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0075","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1046\/j.1365-2362.1998.00393.x","article-title":"Scopolamine model of dementia: electroencephalogram findings and cognitive performance","volume":"28","author":"Ebert","year":"1998","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0080","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0166-4328(99)00186-2","article-title":"Contextual fear, gestalt memories, and the hippocampus","volume":"110","author":"Fanselow","year":"2000","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0085","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.neulet.2006.07.074","article-title":"Rhinal\u2013hippocampal coupling during declarative memory formation: dependence on item characteristics","volume":"407","author":"Fell","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0090","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1093\/brain\/awh647","article-title":"Rhinal\u2013hippocampal connectivity determines memory formation during sleep","volume":"129","author":"Fell","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0095","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.tics.2006.06.003","article-title":"The rhinal cortex: \u2018gatekeeper\u2019 of the declarative memory system","volume":"10","author":"Fernandez","year":"2006","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0100","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/S0022-3565(25)10482-5","article-title":"Quantitative autoradiography of muscarinic cholinergic receptor binding in the rat brain: distinction of receptor subtypes in antagonist competition assays","volume":"263","author":"Frey","year":"1992","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0105","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1046\/j.1365-2125.1997.00606.x","article-title":"Comparison of the effects of a selective muscarinic receptor antagonist and hyoscine (scopolamine) on motion sickness, skin conductance and heart rate","volume":"43","author":"Golding","year":"1997","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0110","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0022-3565(25)33549-4","article-title":"Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response","volume":"225","author":"Harvey","year":"1983","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0115","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.conb.2006.09.002","article-title":"The role of acetylcholine in learning and memory","volume":"16","author":"Hasselmo","year":"2006","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0120","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1055\/s-2007-996315","article-title":"Pharmacotherapy of Alzheimer dementia: therapy of cognitive symptoms\u2014new results of clinical studies","volume":"65","author":"Heidrich","year":"1997","journal-title":"Fortschr. Neurol. Psychiatr."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0125","doi-asserted-by":"crossref","first-page":"e18876","DOI":"10.1371\/journal.pone.0018876","article-title":"Functional connectivity fMRI of the rodent brain: comparison of functional connectivity networks in rat and mouse","volume":"6","author":"Jonckers","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0130","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1159\/000026588","article-title":"EEG changes following scopolamine administration in healthy subjects. Quantitative analysis during rest and photic stimulation","volume":"39","author":"Kikuchi","year":"1999","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0135","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.neubiorev.2010.04.001","article-title":"The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies","volume":"34","author":"Klinkenberg","year":"2010","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0140","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/jcbfm.2014.47","article-title":"Vascular action as the primary mechanism of cognitive effects of cholinergic, CNS-acting drugs, a rat phMRI BOLD study","volume":"34","author":"Kocsis","year":"2014","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0145","doi-asserted-by":"crossref","first-page":"6749","DOI":"10.2174\/13816128113199990711","article-title":"beta-Amyloid, cholinergic transmission, and cerebrovascular system \u2013 a developmental study in a mouse model of Alzheimer's disease","volume":"19","author":"Kuznetsova","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0150","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1037\/a0029698","article-title":"The anterior thalamus is critical for overcoming interference in a context-dependent odor discrimination task","volume":"126","author":"Law","year":"2012","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0155","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/brain\/awt162","article-title":"The role of the posterior cingulate cortex in cognition and disease","volume":"137","author":"Leech","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0160","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nature05453","article-title":"Genome-wide atlas of gene expression in the adult mouse brain","volume":"445","author":"Lein","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0165","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1162\/0898929054475127","article-title":"The role of anterior cingulate cortex in working memory is shaped by functional connectivity","volume":"17","author":"Lenartowicz","year":"2005","journal-title":"J. Cogn. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0170","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.1523\/JNEUROSCI.11-10-03218.1991","article-title":"Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies","volume":"11","author":"Levey","year":"1991","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0175","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.neuroimage.2011.12.077","article-title":"Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment","volume":"60","author":"Li","year":"2012","journal-title":"NeuroImage"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0180","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.1073\/pnas.1200506109","article-title":"Rat brains also have a default mode network","volume":"109","author":"Lu","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0185","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1007\/s00429-013-0586-7","article-title":"A role for anterior thalamic nuclei in contextual fear memory","volume":"219","author":"Marchand","year":"2013","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0190","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0079-6123(03)45004-8","article-title":"The cholinergic innervation of the human cerebral cortex","volume":"145","author":"Mesulam","year":"2004","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0195","first-page":"423","article-title":"Synthesis, rodent biodistribution, dosimetry, metabolism, and monkey images of carbon-11-labeled (+)-2 alpha-tropanyl benzilate: a central muscarinic receptor imaging agent","volume":"33","author":"Mulholland","year":"1992","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0200","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0896-6273(03)00810-9","article-title":"BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease","volume":"41","author":"Ohno","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0205","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.2353\/ajpath.2010.100339","article-title":"Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease","volume":"177","author":"Ongali","year":"2010","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0210","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/ana.23874","article-title":"Cholinergic enhancement of functional networks in older adults with mild cognitive impairment","volume":"73","author":"Pa","year":"2013","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0215","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/jnc.12261","article-title":"Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders","volume":"126","author":"Penzes","year":"2013","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0220","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1101\/lm.68104","article-title":"Changes in acetylcholine extracellular levels during cognitive processes","volume":"11","author":"Pepeu","year":"2004","journal-title":"Learn. Mem."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0225","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/BF00401415","article-title":"Comparative behavioral effects of several anticholinergic agents in rats","volume":"12","author":"Pradhan","year":"1968","journal-title":"Psychopharmacologia"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0230","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0006-8993(95)00422-M","article-title":"Effects of scopolamine infusions into the anterior and posterior cingulate on passive avoidance and water maze navigation","volume":"685","author":"Riekkinen","year":"1995","journal-title":"Brain Res."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0235","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3389\/fpsyt.2013.00105","article-title":"Cholinergic enhancement of brain activation in mild cognitive impairment during episodic memory encoding","volume":"4","author":"Risacher","year":"2013","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0240","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0163-1047(88)90938-7","article-title":"Scopolamine amnesia of passive avoidance: a deficit of information acquisition","volume":"50","author":"Rush","year":"1988","journal-title":"Behav. Neural Biol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0245","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/00002093-199505000-00007","article-title":"Cholinergic neural regulation of regional cerebral blood flow","volume":"9","author":"Sato","year":"1995","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0250","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/joim.12191","article-title":"Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014","volume":"275","author":"Schneider","year":"2014","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0255","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/S0022-3565(24)35171-7","article-title":"Milameline (CI-979\/RU35926): a muscarinic receptor agonist with cognition-activating properties: biochemical and in vivo characterization","volume":"291","author":"Schwarz","year":"1999","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0260","doi-asserted-by":"crossref","first-page":"e84241","DOI":"10.1371\/journal.pone.0084241","article-title":"Resting state FMRI reveals diminished functional connectivity in a mouse model of amyloidosis","volume":"8","author":"Shah","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0265","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.biopsych.2012.11.028","article-title":"Resting state functional connectivity in preclinical Alzheimer's disease","volume":"74","author":"Sheline","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0270","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.clinph.2010.01.008","article-title":"The use of EEG in Alzheimer's disease, with and without scopolamine\u2014a pilot study","volume":"121","author":"Snaedal","year":"2010","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0275","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1073\/pnas.012467899","article-title":"Functional MRI detection of pharmacologically induced memory impairment","volume":"99","author":"Sperling","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0280","doi-asserted-by":"crossref","first-page":"319836","DOI":"10.1155\/2012\/319836","article-title":"Spines, plasticity, and cognition in Alzheimer's model mice","volume":"2012","author":"Spires-Jones","year":"2012","journal-title":"Neural Plast."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0285","doi-asserted-by":"crossref","first-page":"7555","DOI":"10.1523\/JNEUROSCI.1068-06.2006","article-title":"Involvement of the anterior cingulate cortex in the expression of remote spatial memory","volume":"26","author":"Teixeira","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0290","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0165-3806(95)01515-9","article-title":"Distribution of muscarinic receptor subtypes in rat brain from postnatal to old age","volume":"92","author":"Tice","year":"1996","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0295","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.bbr.2009.12.047","article-title":"The cerebrovascular role of the cholinergic neural system in Alzheimer's disease","volume":"221","author":"van Beek","year":"2011","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0300","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.euroneuro.2010.03.008","article-title":"Exploring the brain network: a review on resting-state fMRI functional connectivity","volume":"20","author":"van den Heuvel","year":"2010","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0305","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s11910-010-0104-8","article-title":"Synapse pathology in psychiatric and neurologic disease","volume":"10","author":"van Spronsen","year":"2010","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0310","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.brainres.2008.10.029","article-title":"Decreased acetylcholine release is correlated to memory impairment in the Tg2576 transgenic mouse model of Alzheimer's disease","volume":"1249","author":"Watanabe","year":"2009","journal-title":"Brain Res."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0315","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1146\/annurev.pharmtox.44.101802.121622","article-title":"Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications","volume":"44","author":"Wess","year":"2004","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0320","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-23274-9_6","article-title":"Novel muscarinic receptor mutant mouse models","volume":"95\u2013117","author":"Wess","year":"2012","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0325","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/j.neurobiolaging.2005.08.011","article-title":"Age and cholinergic effects on hemodynamics and functional coherence of human hippocampus","volume":"27","author":"Wink","year":"2006","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0335","doi-asserted-by":"crossref","first-page":"14096","DOI":"10.1073\/pnas.251542998","article-title":"Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice","volume":"98","author":"Yamada","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0330","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.lfs.2003.09.022","article-title":"Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology","volume":"74","author":"Yamada","year":"2003","journal-title":"Life Sci."},{"key":"10.1016\/j.neuroimage.2015.01.009_bb0340","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2174\/1567205043331992","article-title":"Alzheimer's disease: interactions between cholinergic functions and beta-amyloid","volume":"1","author":"Yan","year":"2004","journal-title":"Curr. Alzheimer Res."}],"container-title":["NeuroImage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811915000154?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811915000154?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T12:33:58Z","timestamp":1747398838000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053811915000154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":68,"alternative-id":["S1053811915000154"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroimage.2015.01.009","relation":{},"ISSN":["1053-8119"],"issn-type":[{"value":"1053-8119","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute modulation of the cholinergic system in the mouse brain detected by pharmacological resting-state functional MRI","name":"articletitle","label":"Article Title"},{"value":"NeuroImage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroimage.2015.01.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}