{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:44:27Z","timestamp":1792813467975,"version":"4.5.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T00:00:00Z","timestamp":1722211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000957","name":"Alzheimer's Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["1 R01 AG074584-01"],"award-info":[{"award-number":["1 R01 AG074584-01"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["S10 RR025671"],"award-info":[{"award-number":["S10 RR025671"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DMR-1644779"],"award-info":[{"award-number":["DMR-1644779"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000090","name":"CDMRP","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000090","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007698","name":"University of Florida","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007698","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012892","name":"National High Magnetic Field Laboratory","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003187","name":"NSF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010935","name":"Niagara University","doi-asserted-by":"publisher","award":["1 R01 AG074584-01"],"award-info":[{"award-number":["1 R01 AG074584-01"]}],"id":[{"id":"10.13039\/100010935","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010935","name":"Niagara University","doi-asserted-by":"publisher","award":["S10 RR025671"],"award-info":[{"award-number":["S10 RR025671"]}],"id":[{"id":"10.13039\/100010935","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100023043","name":"State of Florida","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100023043","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019255","name":"Nihon Kohden America","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019255","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.neuroimage.2024.120764","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T07:29:18Z","timestamp":1722324558000},"page":"120764","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Age dictates brain functional connectivity and axonal integrity following repetitive mild traumatic brain injuries in mice"],"prefix":"10.1016","volume":"298","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8307-0183","authenticated-orcid":false,"given":"Marangelie","family":"Criado-Marrero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5159-6030","authenticated-orcid":false,"given":"Sakthivel","family":"Ravi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5389-3340","authenticated-orcid":false,"given":"Ekta","family":"Bhaskar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daylin","family":"Barroso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Pizzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4030-5947","authenticated-orcid":false,"given":"Lakiesha","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7014-039X","authenticated-orcid":false,"given":"Cheryl L.","family":"Wellington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Febo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6341-679X","authenticated-orcid":false,"given":"Jose Francisco","family":"Abisambra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroimage.2024.120764_bib0002","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3233\/JAD-131019","article-title":"Brain injury in the context of tauopathies","volume":"40","author":"Abisambra","year":"2014","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0003","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1089\/neu.2008.0765","article-title":"Impaired expression of neuroprotective molecules in the HIF-1alpha pathway following traumatic brain injury in aged mice","volume":"26","author":"Anderson","year":"2009","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113180","article-title":"The effects of mild closed head injuries on tauopathy and cognitive deficits in rodents: primary results in wild type and rTg4510 mice, and a systematic review","volume":"326","author":"Bachstetter","year":"2020","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0005","first-page":"13","article-title":"Loss of consciousness and righting reflex following traumatic brain injury: predictors of post-injury symptom development (A Narrative Review)","author":"Berman","year":"2023","journal-title":"Brain Sci."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0006","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s13195-021-00793-9","article-title":"Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury","volume":"13","author":"Button","year":"2021","journal-title":"Alzheimers Res. Ther."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2021.108765","article-title":"Better living through understanding the insula: why subregions can make all the difference","volume":"198","author":"Centanni","year":"2021","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0001","unstructured":"Centers for Disease Control and Prevention, http:\/\/wonder.cdc.gov\/ (2023)."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0008","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1089\/neu.2016.4870","article-title":"Repetitive closed-head impact model of engineered rotational acceleration induces long-term cognitive impairments with persistent astrogliosis and microgliosis in mice","volume":"34","author":"Chen","year":"2017","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0009","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13195-018-0461-0","article-title":"CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP\/PS1 mice","volume":"11","author":"Cheng","year":"2019","journal-title":"Alzheimers Res. Ther."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0010","doi-asserted-by":"crossref","first-page":"4517","DOI":"10.1038\/s41598-021-83983-7","article-title":"Signatures of white-matter microstructure degradation during aging and its association with cognitive status","volume":"11","author":"Coelho","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116138","article-title":"Neurite orientation dispersion and density imaging reveals white matter and hippocampal microstructure changes produced by Interleukin-6 in the TgCRND8 mouse model of amyloidosis","volume":"202","author":"Colon-Perez","year":"2019","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0012","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/cbmr.1996.0014","article-title":"AFNI: software for analysis and visualization of functional magnetic resonance neuroimages","volume":"29","author":"Cox","year":"1996","journal-title":"Comput. Biomed. Res."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0013","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.neuroimage.2014.10.026","article-title":"Accelerated microstructure imaging via convex optimization (AMICO) from diffusion MRI data","volume":"105","author":"Daducci","year":"2015","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0014","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1177\/1971400920901706","article-title":"Alterations of connectivity patterns in functional brain networks in patients with mild traumatic brain injury: a longitudinal resting-state functional magnetic resonance imaging study","volume":"33","author":"D\u2019Souza","year":"2020","journal-title":"Neuroradiol. J."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0197346","article-title":"Optic tract injury after closed head traumatic brain injury in mice: a model of indirect traumatic optic neuropathy","volume":"13","author":"Evanson","year":"2018","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0016","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1089\/neu.2020.7195","article-title":"Repetitive mild traumatic brain injuries in mice during adolescence cause sexually dimorphic behavioral deficits and neuroinflammatory dynamics","volume":"37","author":"Eyolfson","year":"2020","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0017","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1089\/neu.2017.5371","article-title":"Geriatric traumatic brain injury: epidemiology, outcomes, knowledge gaps, and future directions","volume":"35","author":"Gardner","year":"2018","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0018","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3389\/fneur.2020.00112","article-title":"The increasing age of TBI patients at a single level 1 trauma center and the discordance between GCS and CT Rotterdam scores in the elderly","volume":"11","author":"Garza","year":"2020","journal-title":"Front. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0019","first-page":"9","article-title":"A whole-brain connectivity map of mouse insular cortex","author":"Gehrlach","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0020","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/j.brs.2020.09.004","article-title":"Age-related differences of motor cortex plasticity in adults: a transcranial direct current stimulation study","volume":"13","author":"Ghasemian-Shirvan","year":"2020","journal-title":"Brain Stimul."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0021","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.neurobiolaging.2016.02.020","article-title":"Age differences in the functional interactions among the default, frontoparietal control, and dorsal attention networks","volume":"41","author":"Grady","year":"2016","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0022","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2023-075049","article-title":"Global, regional and national burden of traumatic brain injury and spinal cord injury, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"13","author":"Guan","year":"2023","journal-title":"BMJ Open"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2023.103392","article-title":"Structural brain network deviations predict recovery after traumatic brain injury","volume":"38","author":"Gugger","year":"2023","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0024","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/s41582-019-0244-7","article-title":"Ageing as a risk factor for neurodegenerative disease","volume":"15","author":"Hou","year":"2019","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0025","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.neuroimage.2012.07.043","article-title":"Regional changes in thalamic shape and volume with increasing age","volume":"63","author":"Hughes","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0026","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.cell.2022.02.006","article-title":"A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement","volume":"185","author":"Inagaki","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0027","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s00424-021-02520-7","article-title":"Resting-state networks in the course of aging-differential insights from studies across the lifespan vs. amongst the old","volume":"473","author":"Jockwitz","year":"2021","journal-title":"Pflugers. Arch."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0028","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3389\/fneur.2016.00156","article-title":"Diffusion tensor imaging findings in post-concussion syndrome patients after mild traumatic brain injury: a systematic review","volume":"7","author":"Khong","year":"2016","journal-title":"Front. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0029","doi-asserted-by":"crossref","first-page":"e2735","DOI":"10.1002\/brb3.2735","article-title":"An exploratory study on functional connectivity after mild traumatic brain injury: preserved global but altered local organization","volume":"12","author":"Kim","year":"2022","journal-title":"Brain Behav."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0030","doi-asserted-by":"crossref","first-page":"3932","DOI":"10.21037\/qims-21-915","article-title":"Rich-club reorganization of functional brain networks in acute mild traumatic brain injury with cognitive impairment","volume":"12","author":"Li","year":"2022","journal-title":"Quant. ImAging Med. Surg."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0031","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/ggi.12013","article-title":"Functional aging impairs the role of feedback in motor learning","volume":"13","author":"Liu","year":"2013","journal-title":"Geriatr. Gerontol. Int."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0032","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1097\/01.ta.0000196002.03681.18","article-title":"Recovery at one year following isolated traumatic brain injury: a Western Trauma Association prospective multicenter trial","volume":"59","author":"Livingston","year":"2005","journal-title":"J. Trauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0033","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1017\/S0033291721004724","article-title":"Depressive symptoms following traumatic brain injury are associated with resting-state functional connectivity","volume":"53","author":"Luo","year":"2023","journal-title":"Psychol. Med."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113409","article-title":"The closed-head impact model of engineered rotational acceleration (CHIMERA) as an application for traumatic brain injury pre-clinical research: a status report","volume":"333","author":"McNamara","year":"2020","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0035","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1089\/neu.2020.7063","article-title":"Alterations in network connectivity after traumatic brain injury in mice","volume":"37","author":"Meningher","year":"2020","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0036","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00429-010-0262-0","article-title":"Saliency, switching, attention and control: a network model of insula function","volume":"214","author":"Menon","year":"2010","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0037","first-page":"1100","article-title":"White matter alterations are associated with cognitive dysfunction decades after moderate-to-severe traumatic brain injury and\/or posttraumatic stress disorder","volume":"6","author":"Mohamed","year":"2021","journal-title":"Biol. Psychiatry Cogn. Neurosci. NeuroimAging"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0038","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3389\/fneur.2020.00369","article-title":"Investigating brain network changes and their association with cognitive recovery after traumatic brain injury: a longitudinal analysis","volume":"11","author":"Moreira da Silva","year":"2020","journal-title":"Front. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0039","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/acn3.510","article-title":"Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury","volume":"5","author":"Mouzon","year":"2018","journal-title":"Ann. Clin. Transl. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0040","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1750-1326-9-55","article-title":"Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury","volume":"9","author":"Namjoshi","year":"2014","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0041","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.expneurol.2017.03.003","article-title":"Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration)","volume":"292","author":"Namjoshi","year":"2017","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0042","doi-asserted-by":"crossref","first-page":"22682","DOI":"10.1073\/pnas.1012651108","article-title":"Longitudinal evidence for diminished frontal cortex function in aging","volume":"107","author":"Nyberg","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0043","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1089\/neu.2007.0430","article-title":"Detrimental effects of aging on outcome from traumatic brain injury: a behavioral, magnetic resonance imaging, and histological study in mice","volume":"25","author":"Onyszchuk","year":"2008","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0044","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1089\/neu.2016.4752","article-title":"Resting-state functional connectivity alterations associated with six-month outcomes in mild traumatic brain injury","volume":"34","author":"Palacios","year":"2017","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0045","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1080\/02699052.2019.1629022","article-title":"Mild traumatic brain injury in the United States: demographics, brain imaging procedures, health-care utilization and costs","volume":"33","author":"Pavlov","year":"2019","journal-title":"Brain Inj."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0046","doi-asserted-by":"crossref","first-page":"19843","DOI":"10.1038\/s41598-020-76935-0","article-title":"Contextual experience modifies functional connectome indices of topological strength and efficiency","volume":"10","author":"Pompilus","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0047","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.apmr.2007.12.035","article-title":"Accuracy of mild traumatic brain injury diagnosis","volume":"89","author":"Powell","year":"2008","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0048","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1089\/neu.2014.3847","article-title":"Is traumatic brain injury associated with reduced inter-hemispheric functional connectivity? A study of large-scale resting state networks following traumatic brain injury","volume":"33","author":"Rigon","year":"2016","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0049","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1089\/neu.2022.0464","article-title":"Fixed time-point analysis reveals repetitive mild traumatic brain injury effects on resting state functional magnetic resonance imaging connectivity and neuro-spatial protein profiles","volume":"40","author":"Sakthivel","year":"2023","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0050","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1001\/jamasurg.2014.13","article-title":"The effect of age on Glasgow Coma Scale score in patients with traumatic brain injury","volume":"149","author":"Salottolo","year":"2014","journal-title":"JAMa Surg."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0051","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.expneurol.2008.06.013","article-title":"Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury","volume":"213","author":"Sandhir","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0052","doi-asserted-by":"crossref","first-page":"S208","DOI":"10.1016\/j.neuroimage.2004.07.051","article-title":"Advances in functional and structural MR image analysis and implementation as FSL","volume":"23 Suppl 1","author":"Smith","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0053","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2023.1259405","article-title":"Traumatic brain injury-associated epigenetic changes and the risk for neurodegenerative diseases","volume":"17","author":"Smolen","year":"2023","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0054","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1089\/brain.2014.0286","article-title":"Age-related reorganizational changes in modularity and functional connectivity of human brain networks","volume":"4","author":"Song","year":"2014","journal-title":"Brain Connect."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0055","doi-asserted-by":"crossref","first-page":"e43829","DOI":"10.1371\/journal.pone.0043829","article-title":"Influence of age on brain edema formation, secondary brain damage and inflammatory response after brain trauma in mice","volume":"7","author":"Timaru-Kast","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0056","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116137","article-title":"MRtrix3: a fast, flexible and open software framework for medical image processing and visualisation","volume":"202","author":"Tournier","year":"2019","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0057","doi-asserted-by":"crossref","first-page":"234","DOI":"10.3389\/fnagi.2019.00234","article-title":"The effect of aging on resting state connectivity of predefined networks in the brain","volume":"11","author":"Varangis","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0058","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.cell.2020.04.007","article-title":"The allen mouse brain common coordinate framework: a 3D reference atlas","volume":"181","author":"Wang","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0059","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3389\/fneur.2018.00092","article-title":"Understanding the physiopathology behind axial and radial diffusivity changes-what do we know?","volume":"9","author":"Winklewski","year":"2018","journal-title":"Front. Neurol."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0060","doi-asserted-by":"crossref","first-page":"eabk0231","DOI":"10.1126\/sciadv.abk0231","article-title":"Distinct roles for motor cortical and thalamic inputs to striatum during motor skill learning and execution","volume":"8","author":"Wolff","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0061","doi-asserted-by":"crossref","first-page":"3484","DOI":"10.1093\/brain\/awad056","article-title":"Acute thalamic connectivity precedes chronic post-concussive symptoms in mild traumatic brain injury","volume":"146","author":"Woodrow","year":"2023","journal-title":"Brain"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0062","doi-asserted-by":"crossref","first-page":"e68910","DOI":"10.1371\/journal.pone.0068910","article-title":"BrainNet Viewer: a network visualization tool for human brain connectomics","volume":"8","author":"Xia","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroimage.2024.120764_bib0063","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s40478-021-01161-2","article-title":"Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes","volume":"9","author":"Xu","year":"2021","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0064","doi-asserted-by":"crossref","first-page":"11178","DOI":"10.1038\/srep11178","article-title":"Temporal MRI characterization, neurobiochemical and neurobehavioral changes in a mouse repetitive concussive head injury model","volume":"5","author":"Yang","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0065","doi-asserted-by":"crossref","first-page":"fcab244","DOI":"10.1093\/braincomms\/fcab244","article-title":"Compensatory functional connectome changes in a rat model of traumatic brain injury","volume":"3","author":"Yang","year":"2021","journal-title":"Brain Commun."},{"key":"10.1016\/j.neuroimage.2024.120764_bib0066","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.neuroimage.2006.01.015","article-title":"User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability","volume":"31","author":"Yushkevich","year":"2006","journal-title":"Neuroimage"}],"container-title":["NeuroImage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811924002611?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811924002611?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T19:31:35Z","timestamp":1742239895000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053811924002611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":66,"alternative-id":["S1053811924002611"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroimage.2024.120764","relation":{},"ISSN":["1053-8119"],"issn-type":[{"value":"1053-8119","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Age dictates brain functional connectivity and axonal integrity following repetitive mild traumatic brain injuries in mice","name":"articletitle","label":"Article Title"},{"value":"NeuroImage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroimage.2024.120764","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120764"}}