{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T11:40:48Z","timestamp":1792237248848,"version":"4.4.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010327","name":"Cincinnati Children\u2019s Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010327","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["UL1TR001425"],"award-info":[{"award-number":["UL1TR001425"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007172","name":"Cincinnati Children's Hospital Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007172","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.neuroimage.2026.122218","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:03:35Z","timestamp":1789052615000},"page":"122218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Atlas-based electrical source imaging for mouse EEG: Application to an Fmr1 knockout model"],"prefix":"10.1016","volume":"340","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7380-2843","authenticated-orcid":false,"given":"Alex D.","family":"Edmondson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Gaulden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Lacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Westerkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaleel","family":"Razak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie R.","family":"Jonak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devin","family":"Binder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Ethridge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Gross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig A.","family":"Erickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest V.","family":"Pedapati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"100","key":"10.1016\/j.neuroimage.2026.122218_bib0001","doi-asserted-by":"crossref","DOI":"10.3791\/52700","article-title":"Brain source imaging in preclinical rat models of focal epilepsy using high-resolution EEG recordings","author":"Bae","year":"2015","journal-title":"J. Visual. Exp."},{"issue":"7247","key":"10.1016\/j.neuroimage.2026.122218_bib0002","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/nature08002","article-title":"Driving fast-spiking cells induces gamma rhythm and controls sensory responses","volume":"459","author":"Cardin","year":"2009","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.neuroimage.2026.122218_bib0003","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.neuron.2015.06.017","article-title":"Altered neuronal and circuit excitability in fragile X syndrome","volume":"87","author":"Contractor","year":"2015","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.neuroimage.2026.122218_bib0004","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0896-6273(00)81138-1","article-title":"Dynamic statistical parametric mapping: combining fMRI and MEG for high-resolution imaging of cortical activity","volume":"26","author":"Dale","year":"2000","journal-title":"Neuron"},{"issue":"12","key":"10.1016\/j.neuroimage.2026.122218_bib0005","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1038\/s41593-020-00744-x","article-title":"Parameterizing neural power spectra into periodic and aperiodic components","volume":"23","author":"Donoghue","year":"2020","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0006","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s13229-017-0140-1","article-title":"Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome","volume":"8","author":"Ethridge","year":"2017","journal-title":"Mol. Autism."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0007","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.neuroimage.2017.06.078","article-title":"Inferring synaptic excitation\/inhibition balance from field potentials","volume":"158","author":"Gao","year":"2017","journal-title":"Neuroimage"},{"issue":"5","key":"10.1016\/j.neuroimage.2026.122218_bib0008","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1152\/jn.90752.2008","article-title":"Imbalance of neocortical excitation and inhibition and altered UP states reflect network hyperexcitability in the mouse model of fragile X syndrome","volume":"100","author":"Gibson","year":"2008","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0009","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3389\/fnins.2013.00267","article-title":"MEG and EEG data analysis with MNE-Python","volume":"7","author":"Gramfort","year":"2013","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.neuroimage.2026.122218_bib0010","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1743-0003-5-25","article-title":"Review on solving the inverse problem in EEG source analysis","volume":"5","author":"Grech","year":"2008","journal-title":"J. Neuroeng. Rehabil."},{"issue":"1","key":"10.1016\/j.neuroimage.2026.122218_bib0011","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF02512476","article-title":"Interpreting magnetic fields of the brain: minimum norm estimates","volume":"32","author":"H\u00e4m\u00e4l\u00e4inen","year":"1994","journal-title":"Med. Biol. Eng. Comput."},{"issue":"3","key":"10.1016\/j.neuroimage.2026.122218_bib0012","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.neuron.2010.01.024","article-title":"Critical period plasticity is disrupted in the barrel cortex of Fmr1 knockout mice","volume":"65","author":"Harlow","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.neuroimage.2026.122218_bib0013","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.neuroimage.2012.09.036","article-title":"A critical assessment of connectivity measures for EEG data: a simulation study","volume":"64","author":"Haufe","year":"2013","journal-title":"Neuroimage"},{"issue":"4","key":"10.1016\/j.neuroimage.2026.122218_bib0014","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1002\/hbm.22279","article-title":"A framework for the design of flexible cross-talk functions for spatial filtering of EEG\/MEG data: DeFleCT","volume":"35","author":"Hauk","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0015","series-title":"Statistical Methods for Meta-Analysis","author":"Hedges","year":"1985"},{"key":"10.1016\/j.neuroimage.2026.122218_bib0016","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3389\/neuro.09.031.2009","article-title":"The human brain in numbers: a linearly scaled-up primate brain","volume":"3","author":"Herculano-Houzel","year":"2009","journal-title":"Front. Hum. Neurosci."},{"issue":"6","key":"10.1016\/j.neuroimage.2026.122218_bib0017","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/nn.3101","article-title":"Large-scale cortical correlation structure of spontaneous oscillatory activity","volume":"15","author":"Hipp","year":"2012","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2024.110182","article-title":"Clinically-probed mechanisms of action in fragile X syndrome fail to normalize translational EEG phenotypes in Fmr1 knockout mice","volume":"262","author":"Janz","year":"2025","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroimage.2026.122218_bib0019","doi-asserted-by":"crossref","DOI":"10.3389\/fninf.2020.589228","article-title":"Electrical source imaging in freely moving rats: evaluation of a 12-electrode cortical electroencephalography system","volume":"14","author":"Jiricek","year":"2021","journal-title":"Front. Neuroinform."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2024.106496","article-title":"Phenotypic analysis of multielectrode array EEG biomarkers in developing and adult male Fmr1 KO mice","volume":"195","author":"Jonak","year":"2024","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2020.104794","article-title":"Multielectrode array analysis of EEG biomarkers in a mouse model of fragile X syndrome","volume":"138","author":"Jonak","year":"2020","journal-title":"Neurobiol. Dis."},{"issue":"9","key":"10.1016\/j.neuroimage.2026.122218_bib0022","doi-asserted-by":"crossref","first-page":"3519","DOI":"10.1002\/hbm.26295","article-title":"Brain-wide network analysis of resting-state neuromagnetic data","volume":"44","author":"Kida","year":"2023","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0023","doi-asserted-by":"crossref","DOI":"10.1038\/s41434-026-00630-4","article-title":"FMR1 gene therapy restores translationally relevant phenotypes in a mouse model for fragile X syndrome","author":"Lacher","year":"2026","journal-title":"Gene Ther."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0024","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.nbd.2018.03.012","article-title":"Translation-relevant EEG phenotypes in a mouse model of fragile X syndrome","volume":"115","author":"Lovelace","year":"2018","journal-title":"Neurobiol. Dis."},{"issue":"5","key":"10.1016\/j.neuroimage.2026.122218_bib0025","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s10548-019-00710-2","article-title":"Variation in reported human head tissue electrical conductivity values","volume":"32","author":"McCann","year":"2019","journal-title":"Brain Topogr."},{"issue":"2","key":"10.1016\/j.neuroimage.2026.122218_bib0026","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.neuroimage.2008.05.016","article-title":"A mouse model for studying large-scale neuronal networks using EEG mapping techniques","volume":"42","author":"M\u00e9gevand","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2026.122218_bib0027","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3389\/fneur.2019.00325","article-title":"EEG source imaging: a practical review of the analysis steps","volume":"10","author":"Michel","year":"2019","journal-title":"Front. Neurol."},{"issue":"10","key":"10.1016\/j.neuroimage.2026.122218_bib0028","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1016\/j.clinph.2004.06.001","article-title":"EEG source imaging","volume":"115","author":"Michel","year":"2004","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0029","series-title":"Electric Fields of the Brain: The Neurophysics of EEG","author":"Nunez","year":"2006"},{"issue":"3","key":"10.1016\/j.neuroimage.2026.122218_bib0030","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/hbm.10061","article-title":"Validating the boundary element method for forward and inverse EEG computations in the presence of a hole in the skull","volume":"17","author":"Oostenveld","year":"2002","journal-title":"Hum. Brain Mapp."},{"issue":"Suppl D","key":"10.1016\/j.neuroimage.2026.122218_bib0031","first-page":"5","article-title":"Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details","volume":"24","author":"Pascual-Marqui","year":"2002","journal-title":"Methods Find. Exp. Clin. Pharmacol."},{"issue":"6","key":"10.1016\/j.neuroimage.2026.122218_bib0032","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1523\/JNEUROSCI.2447-12.2013","article-title":"A target cell-specific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons","volume":"33","author":"Patel","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0033","series-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2012"},{"issue":"1","key":"10.1016\/j.neuroimage.2026.122218_bib0034","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/s42003-022-03395-9","article-title":"Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to fragile X syndrome","volume":"5","author":"Pedapati","year":"2022","journal-title":"Commun. Biol."},{"issue":"1","key":"10.1016\/j.neuroimage.2026.122218_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13195-017-0329-8","article-title":"Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-\u03b2\u2013induced pathology","volume":"10","author":"Praet","year":"2018","journal-title":"Alzheimer\u2019s Res. Therapy"},{"key":"10.1016\/j.neuroimage.2026.122218_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneumeth.2020.108991","article-title":"High-dimensional brain-wide functional connectivity mapping in magnetoencephalography","volume":"348","author":"Sanchez-Bornot","year":"2021","journal-title":"J. Neurosci. Methods"},{"issue":"6","key":"10.1016\/j.neuroimage.2026.122218_bib0037","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1002\/hbm.20745","article-title":"Source connectivity analysis with MEG and EEG","volume":"30","author":"Schoffelen","year":"2009","journal-title":"Hum. Brain Mapp."},{"issue":"3","key":"10.1016\/j.neuroimage.2026.122218_bib0038","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.neulet.2006.11.062","article-title":"Major defects in neocortical GABAergic inhibitory circuits in mice lacking the fragile X mental retardation protein","volume":"412","author":"Selby","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuroimage.2026.122218_bib0039","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.neuroimage.2014.06.040","article-title":"A guideline for head volume conductor modeling in EEG and MEG","volume":"100","author":"Vorwerk","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2026.122218_bib0040","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s11689-017-9191-z","article-title":"A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome","volume":"9","author":"Wang","year":"2017","journal-title":"J. Neurodev. Disord."},{"issue":"4","key":"10.1016\/j.neuroimage.2026.122218_bib0041","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.cell.2020.04.007","article-title":"The Allen mouse brain common coordinate framework: a 3D reference atlas","volume":"181","author":"Wang","year":"2020","journal-title":"Cell"}],"container-title":["NeuroImage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811926005331?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811926005331?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:49:49Z","timestamp":1792234189000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053811926005331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":41,"alternative-id":["S1053811926005331"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroimage.2026.122218","relation":{},"ISSN":["1053-8119"],"issn-type":[{"value":"1053-8119","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Atlas-based electrical source imaging for mouse EEG: Application to an Fmr1 knockout model","name":"articletitle","label":"Article Title"},{"value":"NeuroImage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroimage.2026.122218","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"122218"}}