{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:53:40Z","timestamp":1773100420753,"version":"3.50.1"},"reference-count":49,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["neuromodulationjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuromodulation: Technology at the Neural Interface"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.neurom.2022.01.004","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T17:01:52Z","timestamp":1645722112000},"page":"394-402","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Energy Delivered by Subthalamic Deep Brain Stimulation for Parkinson Disease Correlates With Depressive Personality Trait Shift"],"prefix":"10.1016","volume":"26","author":[{"given":"Francesca","family":"Mameli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana","family":"Ruggiero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelangelo","family":"Dini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Marceglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Prenassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Borellini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Cogiamanian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Pirola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi Gianmaria","family":"Remore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Fiore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Rita","family":"Reitano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natale","family":"Maiorana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Poletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Locatelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Barbieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Priori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5109-9483","authenticated-orcid":false,"given":"Roberta","family":"Ferrucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurom.2022.01.004_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0178984","article-title":"Adverse events in deep brain stimulation: a retrospective long-term analysis of neurological, psychiatric and other occurrences","volume":"12","author":"Buhmann","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.neurom.2022.01.004_bib2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/mds.26468","article-title":"Psychiatric and social outcome after deep brain stimulation for advanced Parkinson\u2019s disease","volume":"31","author":"Boel","year":"2016","journal-title":"Mov Disord"},{"key":"10.1016\/j.neurom.2022.01.004_bib3","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3389\/fneur.2019.00617","article-title":"Mood effects after deep brain stimulation for Parkinson\u2019s disease: an update","volume":"10","author":"Accolla","year":"2019","journal-title":"Front Neurol"},{"key":"10.1016\/j.neurom.2022.01.004_bib4","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1001\/jama.2008.929","article-title":"Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial","volume":"301","author":"Weaver","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.neurom.2022.01.004_bib5","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1056\/NEJMoa0907083","article-title":"Pallidal versus subthalamic deep-brain stimulation for Parkinson\u2019s disease","volume":"362","author":"Follett","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.neurom.2022.01.004_bib6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s11065-020-09467-z","article-title":"Deep brain stimulation of the subthalamic nucleus in Parkinson\u2019s disease: a meta-analysis of mood effects","volume":"31","author":"Cartmill","year":"2021","journal-title":"Neuropsychol Rev"},{"key":"10.1016\/j.neurom.2022.01.004_bib7","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S1474-4422(13)70294-1","article-title":"Mood and behavioural effects of subthalamic stimulation in Parkinson\u2019s disease","volume":"13","author":"Castrioto","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neurom.2022.01.004_bib8","first-page":"490507","article-title":"Personality changes after deep brain stimulation in Parkinson\u2019s disease","volume":"2015","author":"Pham","year":"2015","journal-title":"Parkinsons Dis"},{"key":"10.1016\/j.neurom.2022.01.004_bib9","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s12152-019-09419-2","article-title":"Changes in personality associated with deep brain stimulation: a qualitative evaluation of clinician perspectives","volume":"14","author":"Thomson","year":"2021","journal-title":"Neuroethics"},{"key":"10.1016\/j.neurom.2022.01.004_bib10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/mds.26049","article-title":"Parkinson\u2019s disease, the subthalamic nucleus, inhibition, and impulsivity","volume":"30","author":"Jahanshahi","year":"2015","journal-title":"Mov Disord"},{"key":"10.1016\/j.neurom.2022.01.004_bib11","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s12152-017-9334-7","article-title":"Deep brain stimulation: inducing self-estrangement","volume":"11","author":"Gilbert","year":"2018","journal-title":"Neuroethics"},{"key":"10.1016\/j.neurom.2022.01.004_bib12","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.parkreldis.2013.07.026","article-title":"Relationship between sleep disorders and other non-motor symptoms in Parkinson\u2019s disease","volume":"19","author":"Kurtis","year":"2013","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.neurom.2022.01.004_bib13","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3390\/brainsci6030040","article-title":"Deep brain stimulation: in search of reliable instruments for assessing complex personality-related changes","volume":"6","author":"Ineichen","year":"2016","journal-title":"Brain Sci"},{"key":"10.1016\/j.neurom.2022.01.004_bib14","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1136\/jnnp.72.6.701","article-title":"Behavioural disorders, Parkinson\u2019s disease and subthalamic stimulation","volume":"72","author":"Houeto","year":"2002","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.neurom.2022.01.004_bib15","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000093213","article-title":"Chronic deep brain stimulation of the subthalamic nucleus for Parkinson\u2019s disease: effects on cognition, mood, anxiety and personality traits","volume":"55","author":"Castelli","year":"2006","journal-title":"Eur Neurol"},{"key":"10.1016\/j.neurom.2022.01.004_bib16","doi-asserted-by":"crossref","first-page":"643277","DOI":"10.3389\/fpsyg.2021.643277","article-title":"Does personality change follow deep brain stimulation in Parkinson\u2019s disease patients?","volume":"12","author":"Wilt","year":"2021","journal-title":"Front Psychol"},{"key":"10.1016\/j.neurom.2022.01.004_bib17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jad.2017.05.019","article-title":"Clinical predictors of acute response to transcranial direct current stimulation (tDCS) in major depression","volume":"219","author":"D'Urso","year":"2017","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.neurom.2022.01.004_bib18","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.mehy.2008.07.065","article-title":"The subthalamic nucleus is a key-structure of limbic basal ganglia functions","volume":"72","author":"Haegelen","year":"2009","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.neurom.2022.01.004_bib19","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/ner.12183","article-title":"Predictors of the emergence of apathy after bilateral stimulation of the subthalamic nucleus in patients with Parkinson\u2019s disease","volume":"18","author":"Higuchi","year":"2015","journal-title":"Neuromodulation"},{"key":"10.1016\/j.neurom.2022.01.004_bib20","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1136\/jnnp-2019-321140","article-title":"Subthalamic suppression defines therapeutic threshold of deep brain stimulation in Parkinson\u2019s disease","volume":"90","author":"Milosevic","year":"2019","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.neurom.2022.01.004_bib21","first-page":"14572","article-title":"Core assessment program for surgical interventional therapies in Parkinson\u2019s disease (CAPSIT-PD)","author":"Defer","year":"1999","journal-title":"Mov Disord"},{"key":"10.1016\/j.neurom.2022.01.004_bib22","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s12877-015-0112-2","article-title":"Short term surgical complications after subthalamic deep brain stimulation for Parkinson\u2019s disease: does old age matter?","volume":"15","author":"Levi","year":"2015","journal-title":"BMC Geriatr"},{"key":"10.1016\/j.neurom.2022.01.004_bib23","series-title":"Parkinson\u2019s Disease and Movement Disorders","first-page":"225","article-title":"Clinical rating scale for tremor","author":"Fahn","year":"1998"},{"key":"10.1016\/j.neurom.2022.01.004_bib24","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A\u00a0new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.neurom.2022.01.004_bib25","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1002\/1099-1166(200007)15:7<644::AID-GPS167>3.0.CO;2-L","article-title":"The validity of the Hamilton and Montgomery-Asberg depression rating scales as screening and diagnostic tools for depression in Parkinson\u2019s disease","volume":"15","author":"Leentjens","year":"2000","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.neurom.2022.01.004_bib26","series-title":"The Corsini Encyclopedia of Psychology","article-title":"Minnesota Multiphasic Personality Inventory","author":"Butcher","year":"2010"},{"key":"10.1016\/j.neurom.2022.01.004_bib27","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.parkreldis.2006.06.006","article-title":"Cross-cultural evaluation of the short form 8-item Parkinson\u2019s Disease Questionnaire (PDQ-8): results from America, Canada, Japan, Italy and Spain","volume":"13","author":"Jenkinson","year":"2007","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.neurom.2022.01.004_bib28","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/ana.20525","article-title":"Calculating total electrical energy delivered by deep brain stimulation systems","volume":"58","author":"Koss","year":"2005","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neurom.2022.01.004_bib29","doi-asserted-by":"crossref","first-page":"643841","DOI":"10.3389\/fneur.2021.643841","article-title":"The relationship between electrical energy delivered by deep brain stimulation and levodopa-induced dyskinesias in Parkinson\u2019s disease: a retrospective preliminary analysis","volume":"12","author":"Prenassi","year":"2021","journal-title":"Front Neurol"},{"key":"10.1016\/j.neurom.2022.01.004_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000455863","article-title":"Changes in quality of life in Parkinson\u2019s disease: how large must they be to be relevant?","volume":"48","author":"Horv\u00e1th","year":"2017","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.neurom.2022.01.004_bib31","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1176\/appi.neuropsych.16010004","article-title":"Depression symptoms in chronic left hemisphere stroke are related to dorsolateral prefrontal cortex damage","volume":"28","author":"Grajny","year":"2016","journal-title":"J\u00a0Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.neurom.2022.01.004_bib32","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.biopsych.2007.05.033","article-title":"Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: an fMRI study in severe major depressive disorder","volume":"63","author":"Grimm","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neurom.2022.01.004_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0925-4927(02)00032-X","article-title":"Correlation of cerebral blood flow and treatment effects of repetitive transcranial magnetic stimulation in depressed patients","volume":"115","author":"Mottaghy","year":"2002","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.neurom.2022.01.004_bib34","first-page":"246","article-title":"Comparative benefits of transcranial direct current stimulation (tDCS) treatment in patients with mild\/moderate vs. severe depression","volume":"6","author":"Ferrucci","year":"2009","journal-title":"Clin Neuropsychiatry"},{"key":"10.1016\/j.neurom.2022.01.004_bib35","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.biopsych.2008.05.034","article-title":"Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression","volume":"64","author":"Lozano","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neurom.2022.01.004_bib36","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/0166-2236(90)90107-L","article-title":"Functional architecture of basal ganglia circuits: neural substrates of parallel processing","volume":"13","author":"Alexander","year":"1990","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neurom.2022.01.004_bib37","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1002\/ana.25734","article-title":"Left prefrontal connectivity links subthalamic stimulation with depressive symptoms","volume":"87","author":"Irmen","year":"2020","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neurom.2022.01.004_bib38","doi-asserted-by":"crossref","first-page":"10661","DOI":"10.1073\/pnas.0610849104","article-title":"Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior","volume":"104","author":"Mallet","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neurom.2022.01.004_bib39","doi-asserted-by":"crossref","first-page":"19924","DOI":"10.1038\/s41598-019-56260-x","article-title":"Topography of emotional valence and arousal within the motor part of the subthalamic nucleus in Parkinson\u2019s disease","volume":"9","author":"Serranov\u00e1","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.neurom.2022.01.004_bib40","doi-asserted-by":"crossref","first-page":"3592","DOI":"10.1093\/brain\/awz285","article-title":"Non-motor outcomes depend on location of neurostimulation in Parkinson\u2019s disease","volume":"142","author":"Petry-Schmelzer","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.neurom.2022.01.004_bib41","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1212\/01.WNL.0000032756.14298.18","article-title":"Effect on mood of subthalamic DBS for Parkinson\u2019s disease: a consecutive series of 24 patients","volume":"59","author":"Berney","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.neurom.2022.01.004_bib42","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1093\/brain\/aww020","article-title":"Tractography patterns of subthalamic nucleus deep brain stimulation","volume":"139","author":"Vanegas-Arroyave","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.neurom.2022.01.004_bib43","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1093\/brain\/awaa148","article-title":"The structural connectivity of subthalamic deep brain stimulation correlates with impulsivity in Parkinson\u2019s disease","volume":"143","author":"Mosley","year":"2020","journal-title":"Brain"},{"key":"10.1016\/j.neurom.2022.01.004_bib44","first-page":"409","article-title":"Neurosurgery in Parkinson\u2019s disease: the doctor is happy, the patient less so?","volume":"70","author":"Agid","year":"2006","journal-title":"J\u00a0Neural Transm Suppl"},{"key":"10.1016\/j.neurom.2022.01.004_bib45","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1212\/01.wnl.0000234880.51322.16","article-title":"Neurosurgery in Parkinson disease: a distressed mind in a repaired body?","volume":"66","author":"Sch\u00fcpbach","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.neurom.2022.01.004_bib46","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1002\/da.21993","article-title":"Self-report and clinician-rated measures of depression severity: can one replace the other?","volume":"29","author":"Uher","year":"2012","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.neurom.2022.01.004_bib47","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1177\/0891988713481269","article-title":"Barriers to mental health care utilization in Parkinson\u2019s disease","volume":"26","author":"Dobkin","year":"2013","journal-title":"J\u00a0Geriatr Psychiatry Neurol"},{"key":"10.1016\/j.neurom.2022.01.004_bib48","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S1353-8020(01)00015-3","article-title":"Non-recognition of depression and other non-motor symptoms in Parkinson\u2019s disease","volume":"8","author":"Shulman","year":"2002","journal-title":"Parkinsonism Relat Disord"},{"issue":"suppl 14","key":"10.1016\/j.neurom.2022.01.004_bib49","doi-asserted-by":"crossref","first-page":"S305","DOI":"10.1002\/mds.20963","article-title":"Deep brain stimulation: neuropsychological and neuropsychiatric issues","volume":"21","author":"Voon","year":"2006","journal-title":"Mov Disord"}],"container-title":["Neuromodulation: Technology at the Neural Interface"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094715922000241?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094715922000241?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T10:06:50Z","timestamp":1675418810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1094715922000241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S1094715922000241"],"URL":"https:\/\/doi.org\/10.1016\/j.neurom.2022.01.004","relation":{},"ISSN":["1094-7159"],"issn-type":[{"value":"1094-7159","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Energy Delivered by Subthalamic Deep Brain Stimulation for Parkinson Disease Correlates With Depressive Personality Trait Shift","name":"articletitle","label":"Article Title"},{"value":"Neuromodulation: Technology at the Neural Interface","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurom.2022.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 International Neuromodulation Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}