{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:24:05Z","timestamp":1791217445170,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":3150,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuron"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1016\/j.neuron.2004.11.023","type":"journal-article","created":{"date-parts":[[2004,12,16]],"date-time":"2004-12-16T15:34:26Z","timestamp":1103211266000},"page":"769-778","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":155,"title":["Functional Recovery in a Primate Model of Parkinson's Disease following Motor Cortex Stimulation"],"prefix":"10.1016","volume":"44","author":[{"given":"Xavier","family":"Drouot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Oshino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bechir","family":"Jarraya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Besret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Kishima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Remy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Dauguet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Pascal","family":"Lefaucheur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Doll\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Cond\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Bottlaender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Peschanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"K\u00e9ravel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Hantraye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Palfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuron.2004.11.023_BIB1","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1523\/JNEUROSCI.22-02-00592.2002","article-title":"Effects of transient focal inactivation of the basal ganglia in parkinsonian primates","volume":"22","author":"Baron","year":"2002","journal-title":"J. Neurosci"},{"key":"10.1016\/j.neuron.2004.11.023_BIB2","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1056\/NEJM199905133401905","article-title":"Transient acute depression induced by high-frequency deep-brain stimulation","volume":"340","author":"Bejjani","year":"1999","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.neuron.2004.11.023_BIB3","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1460-9568.1993.tb00505.x","article-title":"Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys","volume":"5","author":"Benazzouz","year":"1993","journal-title":"Eur. J. Neurosci"},{"key":"10.1016\/j.neuron.2004.11.023_BIB4","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0166-2236(02)02235-X","article-title":"Move to the rhythm","volume":"25","author":"Bevan","year":"2002","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuron.2004.11.023_BIB5","first-page":"1092","article-title":"Structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of Parkinson's disease","volume":"15","author":"Bezard","year":"2001","journal-title":"FASEB J"},{"key":"10.1016\/j.neuron.2004.11.023_BIB6","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0166-2236(90)90110-V","article-title":"Primate models of movement disorders of basal ganglia origin","volume":"13","author":"DeLong","year":"1990","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuron.2004.11.023_BIB7","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1152\/jn.2000.84.1.570","article-title":"Microstimulation-induced inhibition of neuronal firing in human globus pallidus","volume":"84","author":"Dostrovsky","year":"2000","journal-title":"J. Neurophysiol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/brain\/awg004","article-title":"Disruption of information processing in the supplementary motor area of the MPTP-treated monkey","volume":"126","author":"Escola","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.neuron.2004.11.023_BIB9","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/1531-8249(20010201)49:2<155::AID-ANA35>3.0.CO;2-9","article-title":"Functional correlates of pallidal stimulation for Parkinson's disease","volume":"49","author":"Fukuda","year":"2001","journal-title":"Ann. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB10","doi-asserted-by":"crossref","first-page":"4639","DOI":"10.1523\/JNEUROSCI.22-11-04639.2002","article-title":"Enhanced synchrony among primary motor cortex neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of Parkinson's disease","volume":"22","author":"Goldberg","year":"2002","journal-title":"J. Neurosci"},{"key":"10.1016\/j.neuron.2004.11.023_BIB11","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1002\/ana.410370611","article-title":"Pallidotomy increases activity of motor association cortex in Parkinson's disease","volume":"37","author":"Grafton","year":"1995","journal-title":"Ann. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB12","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/nm0996-1017","article-title":"Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons","volume":"2","author":"Hantraye","year":"1996","journal-title":"Nat. Med"},{"key":"10.1016\/j.neuron.2004.11.023_BIB13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0165-0270(01)00491-5","article-title":"A template subtraction method for stimulus artifact removal in high-frequency deep brain stimulation","volume":"113","author":"Hashimoto","year":"2002","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.neuron.2004.11.023_BIB14","doi-asserted-by":"crossref","first-page":"7850","DOI":"10.1523\/JNEUROSCI.22-18-07850.2002","article-title":"Dopamine replacement therapy reverses abnormal synchronization of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of parkinsonism","volume":"22","author":"Heimer","year":"2002","journal-title":"J. Neurosci"},{"key":"10.1016\/j.neuron.2004.11.023_BIB15","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1136\/jnnp.72.6.701","article-title":"Behavioural disorders, Parkinson's disease and subthalamic stimulation","volume":"72","author":"Houeto","year":"2002","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neuron.2004.11.023_BIB16","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1002\/ana.410320608","article-title":"Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine","volume":"32","author":"Jenkins","year":"1992","journal-title":"Ann. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB17","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1093\/brain\/121.3.451","article-title":"Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease","volume":"121","author":"Krack","year":"1998","journal-title":"Brain"},{"key":"10.1016\/j.neuron.2004.11.023_BIB18","doi-asserted-by":"crossref","first-page":"S188","DOI":"10.1002\/mds.10163","article-title":"Postoperative management of subthalamic nucleus stimulation for Parkinson's disease","volume":"17","author":"Krack","year":"2002","journal-title":"Mov. Disord. Suppl"},{"key":"10.1016\/j.neuron.2004.11.023_BIB19","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1093\/brain\/awf128","article-title":"Dependence of subthalamic nucleus oscillations on movement and dopamine in Parkinson's disease","volume":"125","author":"Levy","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.neuron.2004.11.023_BIB20","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/ana.410420303","article-title":"Changes in cerebral activity pattern due to subthalamic nucleus or internal pallidum stimulation in Parkinson's disease","volume":"42","author":"Limousin","year":"1997","journal-title":"Ann. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB21","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1056\/NEJM199810153391603","article-title":"Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease","volume":"339","author":"Limousin","year":"1998","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.neuron.2004.11.023_BIB22","doi-asserted-by":"crossref","first-page":"15222","DOI":"10.1073\/pnas.96.26.15222","article-title":"Thalamocortical dysrhythmia","volume":"96","author":"Llinas","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuron.2004.11.023_BIB23","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0306-4522(01)00281-0","article-title":"Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus network","volume":"106","author":"Magill","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuron.2004.11.023_BIB24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0262-8856(00)00052-4","article-title":"Reconstructing a 3D structure from serial histological sections","volume":"19","author":"Ourselin","year":"2001","journal-title":"Image Vis. Comput"},{"key":"10.1016\/j.neuron.2004.11.023_BIB25","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/ana.410390505","article-title":"Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys","volume":"39","author":"Papa","year":"1996","journal-title":"Ann. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB26","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/jcbfm.1985.87","article-title":"Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data","volume":"5","author":"Patlak","year":"1985","journal-title":"Generalizations. J. Cereb. Blood Flow Metab"},{"key":"10.1016\/j.neuron.2004.11.023_BIB27","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/ana.410320206","article-title":"Impaired mesial frontal and putamen activation in Parkinson's disease","volume":"32","author":"Playford","year":"1992","journal-title":"Ann. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB28","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1097\/00004647-200107000-00003","article-title":"Anatomic and biochemical correlates of the dopamine transporter ligand 11C-PE2I in normal and parkinsonian primates","volume":"21","author":"Poyot","year":"2001","journal-title":"J. Cereb. Blood Flow Metab"},{"key":"10.1016\/j.neuron.2004.11.023_BIB29","doi-asserted-by":"crossref","first-page":"8559","DOI":"10.1523\/JNEUROSCI.20-22-08559.2000","article-title":"Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and the tremulous 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine vervet model of parkinsonism","volume":"20","author":"Raz","year":"2000","journal-title":"J. Neurosci"},{"key":"10.1016\/j.neuron.2004.11.023_BIB30","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1001\/archneur.59.4.580","article-title":"Dopaminergic function and dopamine transporter binding assessed with positron emission tomography in Parkinson disease","volume":"59","author":"Ribeiro","year":"2002","journal-title":"Arch. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB31","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1096\/fj.03-0163com","article-title":"Electrophysiological and metabolic evidence that high-frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata","volume":"17","author":"Tai","year":"2003","journal-title":"FASEB J"},{"key":"10.1016\/j.neuron.2004.11.023_BIB32","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1212\/WNL.60.1.78","article-title":"How do parkinsonian signs return after discontinuation of subthalamic DBS?","volume":"60","author":"Temperli","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.neuron.2004.11.023_BIB33","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1001\/archneur.61.1.89","article-title":"Effects of high-frequency stimulation on subthalamic neuronal activity in parkinsonian patients","volume":"61","author":"Welter","year":"2004","journal-title":"Arch. Neurol"},{"key":"10.1016\/j.neuron.2004.11.023_BIB34","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/23148","article-title":"Oscillations in the basal ganglia","volume":"400","author":"Wichmann","year":"1999","journal-title":"Nature"}],"container-title":["Neuron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627304007573?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627304007573?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T06:32:59Z","timestamp":1760250779000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896627304007573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["S0896627304007573"],"URL":"https:\/\/doi.org\/10.1016\/j.neuron.2004.11.023","relation":{},"ISSN":["0896-6273"],"issn-type":[{"value":"0896-6273","type":"print"}],"subject":[],"published":{"date-parts":[[2004,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional Recovery in a Primate Model of Parkinson's Disease following Motor Cortex Stimulation","name":"articletitle","label":"Article Title"},{"value":"Neuron","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuron.2004.11.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Cell Press. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}