{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:29:05Z","timestamp":1790339345694,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,10]],"date-time":"2019-10-10T00:00:00Z","timestamp":1570665600000},"content-version":"vor","delay-in-days":374,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100009706","name":"EU","doi-asserted-by":"publisher","award":["FET 611687"],"award-info":[{"award-number":["FET 611687"]}],"id":[{"id":"10.13039\/501100009706","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Competence Center in Research (NCCR) in Robotics"},{"DOI":"10.13039\/100009152","name":"Bertarelli Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009152","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuron"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.neuron.2018.08.033","type":"journal-article","created":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T10:43:33Z","timestamp":1537440213000},"page":"37-45.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":355,"title":["Biomimetic Intraneural Sensory Feedback Enhances Sensation Naturalness, Tactile Sensitivity, and Manual Dexterity in a Bidirectional Prosthesis"],"prefix":"10.1016","volume":"100","author":[{"given":"Giacomo","family":"Valle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Mazzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Iberite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"D\u2019Anna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Granata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Controzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Clemente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Rognini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Cipriani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Stieglitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco Maria","family":"Petrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo Maria","family":"Rossini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvestro","family":"Micera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuron.2018.08.033_bib1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.bios.2010.05.010","article-title":"A transverse intrafascicular multichannel electrode (TIME) to interface with the peripheral nerve","volume":"26","author":"Boretius","year":"2010","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.neuron.2018.08.033_bib2","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/35784","article-title":"Rubber hands \u2018feel\u2019 touch that eyes see","volume":"391","author":"Botvinick","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.neuron.2018.08.033_bib3","doi-asserted-by":"crossref","first-page":"056009","DOI":"10.1088\/1741-2560\/8\/5\/056009","article-title":"A computational model for estimating recruitment of primary afferent fibers by intraneural stimulation in the dorsal root ganglia","volume":"8","author":"Bourbeau","year":"2011","journal-title":"J.\u00a0Neural Eng."},{"key":"10.1016\/j.neuron.2018.08.033_bib4","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/nmat4671","article-title":"Pursuing prosthetic electronic skin","volume":"15","author":"Chortos","year":"2016","journal-title":"Nat. Mater."},{"key":"10.1016\/j.neuron.2018.08.033_bib5","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1109\/TNSRE.2015.2500586","article-title":"Non-invasive, temporally discrete feedback of object contact and release improves grasp control of closed-loop myoelectric transradial prostheses","volume":"24","author":"Clemente","year":"2016","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"10.1016\/j.neuron.2018.08.033_bib6","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1109\/TNSRE.2014.2337952","article-title":"Vibrotactile stimulation promotes embodiment of an alien hand in amputees with phantom sensations","volume":"23","author":"D\u2019Alonzo","year":"2015","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"10.1016\/j.neuron.2018.08.033_bib7","doi-asserted-by":"crossref","first-page":"15379","DOI":"10.1038\/s41598-017-15619-8","article-title":"Low perceptual sensitivity to altered video speed in viewing a soccer match","volume":"7","author":"de\u2019Sperati","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuron.2018.08.033_bib8","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3389\/fnins.2016.00286","article-title":"Fascicular topography of the human median nerve for neuroprosthetic surgery","volume":"10","author":"Delgado-Mart\u00ednez","year":"2016","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.neuron.2018.08.033_bib9","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3389\/fnbeh.2012.00037","article-title":"Texture-induced vibrations in the forearm during tactile exploration","volume":"6","author":"Delhaye","year":"2012","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.neuron.2018.08.033_bib10","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1093\/brain\/awn297","article-title":"Upper limb amputees can be induced to experience a rubber hand as their own","volume":"131","author":"Ehrsson","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.neuron.2018.08.033_bib11","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/415429a","article-title":"Humans integrate visual and haptic information in a statistically optimal fashion","volume":"415","author":"Ernst","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neuron.2018.08.033_bib12","doi-asserted-by":"crossref","first-page":"361ra141","DOI":"10.1126\/scitranslmed.aaf8083","article-title":"Intracortical microstimulation of human somatosensory cortex","volume":"8","author":"Flesher","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.neuron.2018.08.033_bib13","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1348\/000712610X492558","article-title":"Corporeal awareness and proprioceptive sense of the phantom","volume":"101","author":"Giummarra","year":"2010","journal-title":"Br. J. Psychol."},{"key":"10.1016\/j.neuron.2018.08.033_bib14","doi-asserted-by":"crossref","first-page":"362ra142","DOI":"10.1126\/scitranslmed.aaf5187","article-title":"The neural basis of perceived intensity in natural and artificial touch","volume":"8","author":"Graczyk","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.neuron.2018.08.033_bib15","first-page":"14","article-title":"The neural signal for skin indentation depth","volume":"3","author":"Horch","year":"1983","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2018.08.033_bib16","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1109\/TNSRE.2011.2162635","article-title":"Object discrimination with an artificial hand using electrical stimulation of peripheral tactile and proprioceptive pathways with intrafascicular electrodes","volume":"19","author":"Horch","year":"2011","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"10.1016\/j.neuron.2018.08.033_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0363-5023(80)80035-9","article-title":"Internal topography of major nerves of the forearm and hand: a current view","volume":"5","author":"Jabaley","year":"1980","journal-title":"J.\u00a0Hand Surg. Am."},{"key":"10.1016\/j.neuron.2018.08.033_bib18","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/nrn2621","article-title":"Coding and use of tactile signals from the fingertips in object manipulation tasks","volume":"10","author":"Johansson","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuron.2018.08.033_bib19","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1152\/jn.1974.37.1.48","article-title":"Reconstruction of population response to a vibratory stimulus in quickly adapting mechanoreceptive afferent fiber population innervating glabrous skin of the monkey","volume":"37","author":"Johnson","year":"1974","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.neuron.2018.08.033_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1109\/HAPTIC.2010.5444670","article-title":"Perceptual thresholds for single vs. multi-finger haptic interaction","author":"King","year":"2010","journal-title":"In 2010 IEEE Haptics Symposium"},{"key":"10.1016\/j.neuron.2018.08.033_bib21","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1152\/jn.1993.70.1.200","article-title":"Thermal and pain sensations evoked by microstimulation in the area of human ventrocaudal nucleus","volume":"70","author":"Lenz","year":"1993","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.neuron.2018.08.033_bib22","doi-asserted-by":"crossref","first-page":"e31203","DOI":"10.1371\/journal.pone.0031203","article-title":"The effect of surface wave propagation on neural responses to vibration in primate glabrous skin","volume":"7","author":"Manfredi","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuron.2018.08.033_bib23","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/brain\/awq361","article-title":"Robotic touch shifts perception of embodiment to a prosthesis in targeted reinnervation amputees","volume":"134","author":"Marasco","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.neuron.2018.08.033_bib24","doi-asserted-by":"crossref","first-page":"386","DOI":"10.5014\/ajot.39.6.386","article-title":"Adult norms for the Box and Block Test of manual dexterity","volume":"39","author":"Mathiowetz","year":"1985","journal-title":"Am. J. Occup. Ther."},{"key":"10.1016\/j.neuron.2018.08.033_bib25","doi-asserted-by":"crossref","first-page":"11687","DOI":"10.1523\/JNEUROSCI.1486-07.2007","article-title":"The neural coding of stimulus intensity: linking the population response of mechanoreceptive afferents with psychophysical behavior","volume":"27","author":"Muniak","year":"2007","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2018.08.033_bib26","doi-asserted-by":"crossref","first-page":"e09148","DOI":"10.7554\/eLife.09148","article-title":"Intraneural stimulation elicits discrimination of textural features by artificial fingertip in intact and amputee humans","volume":"5","author":"Oddo","year":"2016","journal-title":"eLife"},{"key":"10.1016\/j.neuron.2018.08.033_bib27","doi-asserted-by":"crossref","first-page":"257re6","DOI":"10.1126\/scitranslmed.3008933","article-title":"An osseointegrated human-machine gateway for long-term sensory feedback and motor control of artificial limbs","volume":"6","author":"Ortiz-Catalan","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.neuron.2018.08.033_bib28","doi-asserted-by":"crossref","first-page":"eaat3818","DOI":"10.1126\/scirobotics.aat3818","article-title":"Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain","volume":"3","author":"Osborn","year":"2018","journal-title":"Sci. Robot."},{"key":"10.1016\/j.neuron.2018.08.033_bib29","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.clinph.2017.12.027","article-title":"Paradigms for restoration of somatosensory feedback via stimulation of the peripheral nervous system","volume":"129","author":"Pasluosta","year":"2018","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.neuron.2018.08.033_bib30","first-page":"167","article-title":"Sensory control of normal movement and of movement aided by neural prostheses","volume":"227","author":"Prochazka","year":"2015","journal-title":"J.\u00a0Anat."},{"key":"10.1016\/j.neuron.2018.08.033_bib31","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1093\/brain\/121.9.1603","article-title":"The perception of phantom limbs. The D. O. Hebb lecture","volume":"121","author":"Ramachandran","year":"1998","journal-title":"Brain"},{"key":"10.1016\/j.neuron.2018.08.033_bib32","doi-asserted-by":"crossref","first-page":"222ra19","DOI":"10.1126\/scitranslmed.3006820","article-title":"Restoring natural sensory feedback in real-time bidirectional hand prostheses","volume":"6","author":"Raspopovic","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.neuron.2018.08.033_bib33","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1109\/JPROC.2016.2600560","article-title":"Framework for the development of neuroprostheses: from basic understanding by sciatic and median nerves models to bionic legs and hands","volume":"105","author":"Raspopovic","year":"2017","journal-title":"Proc. IEEE"},{"key":"10.1016\/j.neuron.2018.08.033_bib34","article-title":"Multisensory bionic limb to achieve prosthesis embodiment and reduce distorted phantom limb perceptions","author":"Rognini","year":"2018","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"issue":"Pt B","key":"10.1016\/j.neuron.2018.08.033_bib35","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.neuropsychologia.2015.06.010","article-title":"Biomimetic approaches to bionic touch\u00a0through a peripheral nerve interface","volume":"79","author":"Saal","year":"2015","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.neuron.2018.08.033_bib36","doi-asserted-by":"crossref","first-page":"E5693","DOI":"10.1073\/pnas.1704856114","article-title":"Simulating tactile signals from the whole hand with millisecond precision","volume":"114","author":"Saal","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuron.2018.08.033_bib37","doi-asserted-by":"crossref","first-page":"016001","DOI":"10.1088\/1741-2560\/13\/1\/016001","article-title":"Sensory feedback by peripheral nerve stimulation improves task performance in individuals with upper limb loss using a myoelectric prosthesis","volume":"13","author":"Schiefer","year":"2016","journal-title":"J.\u00a0Neural Eng."},{"key":"10.1016\/j.neuron.2018.08.033_bib38","doi-asserted-by":"crossref","first-page":"257ra138","DOI":"10.1126\/scitranslmed.3008669","article-title":"A neural interface provides long-term stable natural touch perception","volume":"6","author":"Tan","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.neuron.2018.08.033_bib39","doi-asserted-by":"crossref","first-page":"026002","DOI":"10.1088\/1741-2560\/12\/2\/026002","article-title":"Stability and selectivity of a chronic, multi-contact cuff electrode for sensory stimulation in human amputees","volume":"12","author":"Tan","year":"2015","journal-title":"J.\u00a0Neural Eng."},{"key":"10.1016\/j.neuron.2018.08.033_bib40","first-page":"8","article-title":"The neural signal for the intensity of a tactile stimulus","volume":"3","author":"Tuckett","year":"1983","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2018.08.033_bib41","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1097\/WCO.0000000000000266","article-title":"Neural interfaces for somatosensory feedback: bringing life to a prosthesis","volume":"28","author":"Tyler","year":"2015","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.neuron.2018.08.033_bib42","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1037\/h0074515","article-title":"The method of constant stimuli and its generalizations","volume":"17","author":"Urban","year":"1910","journal-title":"Psychol. Rev."},{"key":"10.1016\/j.neuron.2018.08.033_bib43","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.cognition.2013.11.020","article-title":"Affective touch modulates the rubber hand illusion","volume":"131","author":"van Stralen","year":"2014","journal-title":"Cognition"},{"key":"10.1016\/j.neuron.2018.08.033_bib44","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s12984-017-0320-4","article-title":"Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves","volume":"14","author":"Wendelken","year":"2017","journal-title":"J.\u00a0Neuroeng. Rehabil."},{"key":"10.1016\/j.neuron.2018.08.033_bib45","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jht.2015.01.013","article-title":"Forearm amputees\u2019 views of prosthesis use and sensory feedback","volume":"28","author":"Wijk","year":"2015","journal-title":"J.\u00a0Hand Ther."}],"container-title":["Neuron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627318307384?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627318307384?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T20:57:21Z","timestamp":1570654641000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896627318307384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0896627318307384"],"URL":"https:\/\/doi.org\/10.1016\/j.neuron.2018.08.033","relation":{},"ISSN":["0896-6273"],"issn-type":[{"value":"0896-6273","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biomimetic Intraneural Sensory Feedback Enhances Sensation Naturalness, Tactile Sensitivity, and Manual Dexterity in a Bidirectional Prosthesis","name":"articletitle","label":"Article Title"},{"value":"Neuron","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuron.2018.08.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}