{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T15:48:08Z","timestamp":1789832888369,"version":"4.0.1"},"reference-count":82,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T00:00:00Z","timestamp":1623888000000},"content-version":"vor","delay-in-days":381,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuron"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.neuron.2020.03.025","type":"journal-article","created":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T10:37:35Z","timestamp":1587465455000},"page":"992-1008.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":146,"title":["Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities"],"prefix":"10.1016","volume":"106","author":[{"given":"Anna Yu-Szu","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junsung","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debosmita","family":"Sardar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittney","family":"Lozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navish A.","family":"Bosquez Huerta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Ching John","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Felice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antrix","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Paulucci-Holthauzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Deneen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuron.2020.03.025_bib1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.neuron.2010.01.009","article-title":"Synaptic inhibition in the olfactory bulb accelerates odor discrimination in mice","volume":"65","author":"Abraham","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.cell.2018.05.002","article-title":"Astrocytic activation generates de novo neuronal potentiation and memory enhancement","volume":"174","author":"Adamsky","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.neuron.2020.03.025_bib3","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3389\/fncel.2013.00135","article-title":"Low micromolar Ba(2+) potentiates glutamate transporter current in hippocampal astrocytes","volume":"7","author":"Afzalov","year":"2013","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib4","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1126\/science.1184821","article-title":"Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling","volume":"327","author":"Agulhon","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.neuron.2020.03.025_bib5","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev-cellbio-100913-013053","article-title":"Astrocyte regulation of synaptic behavior","volume":"30","author":"Allen","year":"2014","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.neuron.2020.03.025_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/1098-1136(200010)32:1<1::AID-GLIA10>3.0.CO;2-W","article-title":"Astrocyte glutamate transport: review of properties, regulation, and physiological functions","volume":"32","author":"Anderson","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.neuron.2020.03.025_bib7","doi-asserted-by":"crossref","first-page":"16878","DOI":"10.1038\/s41598-017-17204-5","article-title":"QuPath: open source software for digital pathology image analysis","volume":"7","author":"Bankhead","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuron.2020.03.025_bib8","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/nn.4201","article-title":"Astrocyte calcium signaling: the third wave","volume":"19","author":"Bazargani","year":"2016","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib9","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrn.2016.159","article-title":"Functional diversity of astrocytes in neural circuit regulation","volume":"18","author":"Ben Haim","year":"2017","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib10","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12915-017-0377-3","article-title":"OptiMouse: a comprehensive open source program for reliable detection and analysis of mouse body and nose positions","volume":"15","author":"Ben-Shaul","year":"2017","journal-title":"BMC Biol."},{"key":"10.1016\/j.neuron.2020.03.025_bib11","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/S0896-6273(00)80420-1","article-title":"Synaptic activation of glutamate transporters in hippocampal astrocytes","volume":"19","author":"Bergles","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/361031a0","article-title":"A synaptic model of memory: long-term potentiation in the hippocampus","volume":"361","author":"Bliss","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.neuron.2020.03.025_bib13","doi-asserted-by":"crossref","first-page":"13572","DOI":"10.1038\/ncomms13572","article-title":"Astrocytic GABA transporter activity modulates excitatory neurotransmission","volume":"7","author":"Boddum","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neuron.2020.03.025_bib14","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.celrep.2017.12.039","article-title":"The aging astrocyte transcriptome from multiple regions of the mouse brain","volume":"22","author":"Boisvert","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.neuron.2020.03.025_bib15","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.pupt.2013.09.004","article-title":"Tiotropium bromide inhibits relapsing allergic asthma in BALB\/c mice","volume":"27","author":"Bosnjak","year":"2014","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.neuron.2020.03.025_bib16","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1523\/JNEUROSCI.22-01-00183.2002","article-title":"Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains","volume":"22","author":"Bushong","year":"2002","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib17","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1242\/dev.02847","article-title":"A crucial role for Olig2 in white matter astrocyte development","volume":"134","author":"Cai","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.neuron.2020.03.025_bib18","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.neuron.2017.06.029","article-title":"Neural circuit-specialized astrocytes: transcriptomic, proteomic, morphological, and functional evidence","volume":"95","author":"Chai","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib19","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1016\/j.celrep.2018.04.090","article-title":"Trpv4 mediates hypotonic inhibition of central osmosensory neurons via taurine gliotransmission","volume":"23","author":"Ciura","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.neuron.2020.03.025_bib20","doi-asserted-by":"crossref","first-page":"11946","DOI":"10.1073\/pnas.96.21.11946","article-title":"Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of the corpus callosum","volume":"96","author":"das Neves","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuron.2020.03.025_bib21","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.neuron.2006.11.019","article-title":"The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord","volume":"52","author":"Deneen","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.neuron.2020.03.025_bib23","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1093\/bioinformatics\/btw354","article-title":"MultiQC: summarize analysis results for multiple tools and samples in a single report","volume":"32","author":"Ewels","year":"2016","journal-title":"Bioinformatics"},{"key":"10.1016\/j.neuron.2020.03.025_bib24","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1126\/science.aab3103","article-title":"Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling","volume":"351","author":"Farmer","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.neuron.2020.03.025_bib25","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1523\/JNEUROSCI.2859-03.2004","article-title":"Intracellular astrocyte calcium waves in\u00a0situ increase the frequency of spontaneous AMPA receptor currents in CA1 pyramidal neurons","volume":"24","author":"Fiacco","year":"2004","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3389\/fnbeh.2014.00081","article-title":"Olfactory tubercle stimulation alters odor preference behavior and recruits forebrain reward and motivational centers","volume":"8","author":"Fitzgerald","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib27","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature10959","article-title":"Local generation of glia is a major astrocyte source in postnatal cortex","volume":"484","author":"Ge","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.neuron.2020.03.025_bib28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.cimid.2015.01.003","article-title":"Comparison of experimental respiratory tularemia in three nonhuman primate species","volume":"39","author":"Glynn","year":"2015","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"10.1016\/j.neuron.2020.03.025_bib29","doi-asserted-by":"crossref","first-page":"2702","DOI":"10.1016\/S0006-3495(98)77976-7","article-title":"Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy","volume":"74","author":"Gordon","year":"1998","journal-title":"Biophys. J."},{"key":"10.1016\/j.neuron.2020.03.025_bib30","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/nature11775","article-title":"LTP requires a reserve pool of glutamate receptors independent of subunit type","volume":"493","author":"Granger","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.neuron.2020.03.025_bib31","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3389\/fncel.2017.00427","article-title":"Functional roles of astrocyte calcium elevations: from synapses to behavior","volume":"11","author":"Guerra-Gomes","year":"2018","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib32","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1165\/rcmb.2009-0355OC","article-title":"Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-\u03b3-mediated airway hyperreactivity in a murine model of natural rubber latex allergy","volume":"44","author":"Haapakoski","year":"2011","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.neuron.2020.03.025_bib33","doi-asserted-by":"crossref","first-page":"6473","DOI":"10.1523\/JNEUROSCI.1419-07.2007","article-title":"Synaptic islands defined by the territory of a single astrocyte","volume":"27","author":"Halassa","year":"2007","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib34","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.bbrc.2007.06.132","article-title":"Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading","volume":"361","author":"Hamaguchi","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.neuron.2020.03.025_bib35","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.neuron.2014.02.041","article-title":"Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway","volume":"82","author":"Haustein","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib36","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.molcel.2010.05.004","article-title":"Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities","volume":"38","author":"Heinz","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.neuron.2020.03.025_bib37","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/nature08673","article-title":"Long-term potentiation depends on release of D-serine from astrocytes","volume":"463","author":"Henneberger","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.neuron.2020.03.025_bib38","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.cell.2008.02.046","article-title":"Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code","volume":"133","author":"Hochstim","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.neuron.2020.03.025_bib39","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1523\/JNEUROSCI.3693-15.2016","article-title":"Dysfunctional calcium and glutamate signaling in striatal astrocytes from Huntington\u2019s disease model mice","volume":"36","author":"Jiang","year":"2016","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib40","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nn.4493","article-title":"Identification of diverse astrocyte populations and their malignant analogs","volume":"20","author":"John Lin","year":"2017","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib41","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1016\/j.neurobiolaging.2015.08.024","article-title":"Aging causes morphological alterations in astrocytes and microglia in human substantia nigra pars compacta","volume":"36","author":"Jyothi","year":"2015","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neuron.2020.03.025_bib42","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neuron.2012.01.024","article-title":"Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis","volume":"74","author":"Kang","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib43","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.tins.2019.06.003","article-title":"Astrocyte-neuron interactions in the striatum: insights on identity, form, and function","volume":"42","author":"Khakh","year":"2019","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib44","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1038\/nn.4043","article-title":"Diversity of astrocyte functions and phenotypes in neural circuits","volume":"18","author":"Khakh","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib45","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neuron.2020.03.025_bib46","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1038\/s41467-018-03940-3","article-title":"Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers","volume":"9","author":"Lanjakornsiripan","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neuron.2020.03.025_bib47","doi-asserted-by":"crossref","first-page":"e1003118","DOI":"10.1371\/journal.pcbi.1003118","article-title":"Software for computing and annotating genomic ranges","volume":"9","author":"Lawrence","year":"2013","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.neuron.2020.03.025_bib48","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1021\/jm00108a002","article-title":"Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor","volume":"34","author":"Leeson","year":"1991","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.neuron.2020.03.025_bib49","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The Sequence Alignment\/Map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.neuron.2020.03.025_bib50","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.neuron.2020.03.025_bib51","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3389\/fnins.2020.00061","article-title":"Regionally distinct astrocytes display unique transcription factor profiles in the adult brain","volume":"14","author":"Lozzi","year":"2020","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib52","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1152\/physrev.00014.2003","article-title":"Long-term potentiation and memory","volume":"84","author":"Lynch","year":"2004","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.neuron.2020.03.025_bib53","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1002\/glia.22836","article-title":"Astrocyte development: a guide for the perplexed","volume":"63","author":"Molofsky","year":"2015","journal-title":"Glia"},{"key":"10.1016\/j.neuron.2020.03.025_bib54","doi-asserted-by":"crossref","first-page":"8706","DOI":"10.1523\/JNEUROSCI.3956-16.2017","article-title":"Molecular and functional properties of regional astrocytes in the adult brain","volume":"37","author":"Morel","year":"2017","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib55","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.neuron.2018.03.003","article-title":"An optical neuron-astrocyte proximity assay at synaptic distance scales","volume":"98","author":"Octeau","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib56","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.tins.2015.07.006","article-title":"Do stars govern our actions? Astrocyte involvement in rodent behavior","volume":"38","author":"Oliveira","year":"2015","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib58","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.cell.2011.07.022","article-title":"Astrocytes are endogenous regulators of basal transmission at central synapses","volume":"146","author":"Panatier","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.neuron.2020.03.025_bib59","doi-asserted-by":"crossref","first-page":"20160154","DOI":"10.1098\/rstb.2016.0154","article-title":"Astrocytic control of synaptic function","volume":"372","author":"Papouin","year":"2017","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.neuron.2020.03.025_bib60","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/369744a0","article-title":"Glutamate-mediated astrocyte-neuron signalling","volume":"369","author":"Parpura","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.neuron.2020.03.025_bib61","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1126\/science.1116916","article-title":"Astrocytic purinergic signaling coordinates synaptic networks","volume":"310","author":"Pascual","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.neuron.2020.03.025_bib62","doi-asserted-by":"crossref","first-page":"5956","DOI":"10.1074\/jbc.M805606200","article-title":"Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc","volume":"284","author":"Paulucci-Holthauzen","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neuron.2020.03.025_bib63","doi-asserted-by":"crossref","first-page":"378","DOI":"10.3389\/fncel.2014.00378","article-title":"Neuron-glia networks: integral gear of brain function","volume":"8","author":"Perea","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib64","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1037\/0735-7044.106.2.274","article-title":"Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning","volume":"106","author":"Phillips","year":"1992","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib65","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1172\/JCI79422","article-title":"Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation","volume":"125","author":"Rajavelu","year":"2015","journal-title":"J.\u00a0Clin. Invest."},{"issue":"W1","key":"10.1016\/j.neuron.2020.03.025_bib66","doi-asserted-by":"crossref","first-page":"W160","DOI":"10.1093\/nar\/gkw257","article-title":"deepTools2: a next generation web server for deep-sequencing data analysis","volume":"44","author":"Ram\u00edrez","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.neuron.2020.03.025_bib67","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1093\/beheco\/ark016","article-title":"The unequal variance t-test is an underused alternative to Student\u2019s t-test and the Mann\u2013Whitney U test","volume":"17","author":"Ruxton","year":"2006","journal-title":"Behav. Ecol."},{"key":"10.1016\/j.neuron.2020.03.025_bib68","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.neuron.2011.02.003","article-title":"TNF\u03b1 controls glutamatergic gliotransmission in the hippocampal dentate gyrus","volume":"69","author":"Santello","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib69","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1523\/JNEUROSCI.0017-17.2017","article-title":"Gliotransmission: beyond black-and-white","volume":"38","author":"Savtchouk","year":"2018","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib83","doi-asserted-by":"crossref","first-page":"3811","DOI":"10.1016\/j.celrep.2018.11.078","article-title":"Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.","volume":"25","author":"Scavuzzo","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.neuron.2020.03.025_bib70","doi-asserted-by":"crossref","first-page":"10143","DOI":"10.1523\/JNEUROSCI.5779-12.2013","article-title":"TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release","volume":"33","author":"Shigetomi","year":"2013","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib71","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.tins.2012.11.004","article-title":"Brainstem respiratory networks: building blocks and microcircuits","volume":"36","author":"Smith","year":"2013","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib72","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/nn.4001","article-title":"Ca(2+) signaling in astrocytes from Ip3r2(-\/-) mice in brain slices and during startle responses in\u00a0vivo","volume":"18","author":"Srinivasan","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib73","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.neuron.2016.11.030","article-title":"New transgenic mouse lines for selectively targeting astrocytes and studying calcium signals in astrocyte processes in\u00a0situ and in\u00a0vivo","volume":"92","author":"Srinivasan","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib74","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1101\/gad.215802","article-title":"Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10","volume":"16","author":"Stolt","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.neuron.2020.03.025_bib75","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0006-3495(84)84240-X","article-title":"Flow cytometric measurement of fluorescence resonance energy transfer on cell surfaces. Quantitative evaluation of the transfer efficiency on a cell-by-cell basis","volume":"45","author":"Tr\u00f3n","year":"1984","journal-title":"Biophys. J."},{"key":"10.1016\/j.neuron.2020.03.025_bib76","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1126\/science.1222381","article-title":"Regional astrocyte allocation regulates CNS synaptogenesis and repair","volume":"337","author":"Tsai","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.neuron.2020.03.025_bib77","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1016\/S0006-3495(04)74307-6","article-title":"Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission","volume":"86","author":"van Rheenen","year":"2004","journal-title":"Biophys. J."},{"key":"10.1016\/j.neuron.2020.03.025_bib78","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/nn1703","article-title":"Astrocytic Ca2+ signaling evoked by sensory stimulation in\u00a0vivo","volume":"9","author":"Wang","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib79","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cell.2012.09.005","article-title":"TREK-1 and Best1 channels mediate fast and slow glutamate release in astrocytes upon GPCR activation","volume":"151","author":"Woo","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.neuron.2020.03.025_bib80","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1038\/nn.4008","article-title":"Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair","volume":"18","author":"Yu","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuron.2020.03.025_bib81","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.neuron.2018.08.015","article-title":"Reducing astrocyte calcium signaling in\u00a0vivo alters striatal microcircuits and causes repetitive behavior","volume":"99","author":"Yu","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.neuron.2020.03.025_bib82","doi-asserted-by":"crossref","first-page":"11.18.1","DOI":"10.1002\/0471140856.tx1118s63","article-title":"Methods to measure olfactory behavior in mice.","volume":"63","author":"Zou","year":"2015","journal-title":"Curr. Protoc. Toxicol."}],"container-title":["Neuron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627320302324?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627320302324?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T07:26:16Z","timestamp":1760253976000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896627320302324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":82,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["S0896627320302324"],"URL":"https:\/\/doi.org\/10.1016\/j.neuron.2020.03.025","relation":{},"ISSN":["0896-6273"],"issn-type":[{"value":"0896-6273","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities","name":"articletitle","label":"Article Title"},{"value":"Neuron","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuron.2020.03.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}