{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:45:04Z","timestamp":1791189904097,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.neuropharm.2006.11.002","type":"journal-article","created":{"date-parts":[[2006,12,28]],"date-time":"2006-12-28T12:06:58Z","timestamp":1167307618000},"page":"1065-1070","source":"Crossref","is-referenced-by-count":30,"title":["Isolation and characterization of rufoxin, a novel protein exhibiting neurotoxicity from venom of the psammophiine, Rhamphiophis oxyrhynchus (Rufous beaked snake)"],"prefix":"10.1016","volume":"52","author":[{"given":"Natalie G.","family":"Lumsden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajnavalka","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Manjunatha","family":"Kini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjaya","family":"Kuruppu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne C.","family":"Hodgson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2006.11.002_bib1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0041-0101(01)00232-X","article-title":"Ophidian envenomation strategies and the role of purines","volume":"40","author":"Aird","year":"2002","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib2","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0041-0101(92)90539-H","article-title":"Hemorrhagic, fibrinogenolytic and edema-forming activities of the venom of the colubrid snake Philodryas olfersii (green snake)","volume":"30","author":"Assakura","year":"1992","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib3","first-page":"155","article-title":"Partial purification of acetylcholine receptor binding components from the Duvernoy's secretions of Blanding's tree snake (Boiga blandingi) and the Mangrove snake (Boiga dendrophila)","volume":"8","author":"Broaders","year":"1999","journal-title":"J. Nat. Toxins"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib4","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0014-2999(99)00550-6","article-title":"The assessment of antagonist potency under conditions of transient response kinetics","volume":"382","author":"Christopoulos","year":"1999","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0041-0101(98)00125-1","article-title":"Structure-function properties of venom components from Australian elapids","volume":"37","author":"Fry","year":"1999","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib6","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s00239-003-2497-3","article-title":"Isolation of a neurotoxin (\u03b1-colubritoxin) from a \u2018non-venomous\u2019 colubrid: evidence for early origin of venom in snakes","volume":"57","author":"Fry","year":"2003","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/rcm.1148","article-title":"Analysis of Colubroidea snake venoms by liquid chromatography with mass spectrometry: evolutionary and toxinological implications","volume":"17","author":"Fry","year":"2003","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib23","doi-asserted-by":"crossref","unstructured":"Greene, H.W., 1997. Snakes: the evolution of mystery in nature. University of California Press, Berkeley, CA.","DOI":"10.1525\/9780520935433"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib8","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0041-0101(94)90078-7","article-title":"Screening of snake venoms for neurotoxic and myotoxic effects using simple in vitro preparations from rodents and chicks","volume":"32","author":"Harvey","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib9","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1046\/j.1440-1681.2002.03740.x","article-title":"The in vitro neuromuscular activity of snake venoms","volume":"29","author":"Hodgson","year":"2002","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib10","unstructured":"Hodgson, W.C., Wickramaratna, J.C., 2004. Pharmacological characterisation of toxins from Death Adder (Acanthophis) venoms. In: Symposium of the Pan American Section of the International Society on Toxinology, Angra dos Reis\/Brazil, P225."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib11","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/S0041-0101(00)00089-1","article-title":"Mass spectrophotometric evidence for P-III\/P-IV metalloproteinases in the venom of the Boomslang (Dispholidus typus)","volume":"38","author":"Kamiguti","year":"2000","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib24","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1096-3642.1998.tb02159.x","article-title":"Phylogenetic relationships of colubroid snakes based on mitochondrial DNA sequences","volume":"122","author":"Kraus","year":"1998","journal-title":"Zool. J. Linn. Soc."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib25","unstructured":"Lumsden, N.G., 2005. A pharmacological and biochemical examination of colubrid venoms. Doctoral dissertation, Monash University, Australia."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib12","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.toxicon.2004.03.012","article-title":"In vitro neuromuscular activity of \u2018colubrid\u2019 venoms: clinical and evolutionary implications","volume":"43","author":"Lumsden","year":"2004","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib13","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.toxicon.2004.11.003","article-title":"Pharmacological characterisation of a neurotoxin from the venom of Boiga dendrophila (Mangrove catsnake)","volume":"45","author":"Lumsden","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib14","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.toxicon.2004.10.010","article-title":"A biochemical and pharmacological examination of Rhamphiophis oxyrhynchus (Rufous beaked snake) venom","volume":"45","author":"Lumsden","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib16","doi-asserted-by":"crossref","first-page":"17811","DOI":"10.1074\/jbc.M111152200","article-title":"Candoxin, a novel toxin from Bungarus candidus, is a reversible antagonist of muscle (\u03b1\u03b2\u03b3\u03b4) but a poorly reversible antagonist of neuronal \u03b17 nicotinic acetylcholine receptors","volume":"277","author":"Nirthanan","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib17","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0041-0101(02)00388-4","article-title":"Non-conventional toxins from Elapid venoms","volume":"41","author":"Nirthanan","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib18","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.toxicon.2004.09.014","article-title":"Weak neurotoxin from Naja kaouthia cobra venom affects haemodynamic regulation by acting on acetylcholine receptors","volume":"45","author":"Ogay","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.neuropharm.2006.11.002_bib19","doi-asserted-by":"crossref","first-page":"29030","DOI":"10.1074\/jbc.M605850200","article-title":"Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity","volume":"281","author":"Pawlak","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib20","doi-asserted-by":"crossref","first-page":"15810","DOI":"10.1074\/jbc.M100788200","article-title":"\u2018Weak toxin\u2019 from Naja kaouthia is a nontoxic antagonist of \u03b1 7 and muscle-type nicotinic acetylcholine receptors","volume":"276","author":"Utkin","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib26","unstructured":"Wickramaratna, J.C., 2003. A pharmacological characterisation of death adder (Acanthophis Spp.) venoms and toxins. Doctoral dissertation. Monash University, Australia."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib21","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.bcp.2004.03.033","article-title":"Isolation and characterisation at cholinergic nicotinic receptors of a neurotoxin from the venom of the Acanthophis sp. Seram death adder","volume":"68","author":"Wickramaratna","year":"2004","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.neuropharm.2006.11.002_bib22","doi-asserted-by":"crossref","first-page":"7910","DOI":"10.1021\/bi9600761","article-title":"Two novel \u03b1-neurotoxins isolated from the Taipan Snake, Oxyuranus scutellatus, exhibit reduced affinity for nicotinic acetylcholine receptors in brain and skeletal muscle","volume":"35","author":"Zamudio","year":"1996","journal-title":"Biochem."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390806003893?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390806003893?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,7]],"date-time":"2021-08-07T03:21:35Z","timestamp":1628306495000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390806003893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0028390806003893"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2006.11.002","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}