{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:52:20Z","timestamp":1791190340614,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1016\/j.neuropharm.2007.10.004","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T15:28:59Z","timestamp":1196177339000},"page":"344-354","source":"Crossref","is-referenced-by-count":54,"title":["Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous and evoked absence seizures"],"prefix":"10.1016","volume":"54","author":[{"given":"R.T.","family":"Ngomba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Ferraguti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Badura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Citraro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Santolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Battaglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Bruno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"De Sarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Simonyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"van Luijtelaar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Nicoletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2007.10.004_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.eplepsyres.2006.05.012","article-title":"Metabotropic glutamate receptors as a strategic target for the treatment of epilepsy","volume":"71","author":"Alexander","year":"2006","journal-title":"Epilepsy Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib2","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/0960-894X(96)00104-7","article-title":"A novel class of antagonist for metabotropic glutamate receptors, 7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxylates","volume":"6","author":"Annoura","year":"1996","journal-title":"Bioorganic & Medicinal Chemistry Letters"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib3","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0920-1211(96)00037-X","article-title":"Cortical versus thalamic mechanisms underlying spike and wave discharges in GAERS","volume":"26","author":"Avanzini","year":"1996","journal-title":"Epilepsy Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib4","doi-asserted-by":"crossref","first-page":"7222","DOI":"10.1523\/JNEUROSCI.1595-06.2006","article-title":"Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine","volume":"26","author":"Battaglia","year":"2006","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib5","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0306-4522(91)90332-I","article-title":"The thalamic clock: emergent network properties","volume":"41","author":"Buzsaki","year":"1991","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib6","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0014-2999(99)00014-X","article-title":"Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid)","volume":"26","author":"Chapman","year":"1999","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib7","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.neulet.2004.11.008","article-title":"Expression analysis of metabotropic glutamate receptors I and III in mouse strains with different susceptibility to experimental temporal lobe epilepsy","volume":"375","author":"Chen","year":"2005","journal-title":"Neuroscience Letters"},{"issue":"Suppl. 6","key":"10.1016\/j.neuropharm.2007.10.004_bib8","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1528-1157.2000.tb01567.x","article-title":"Plasticity of excitatory amino acid transporters in experimental epilepsy","volume":"41","author":"Claudio","year":"2000","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib9","doi-asserted-by":"crossref","first-page":"3629","DOI":"10.1046\/j.1460-9568.1998.00371.x","article-title":"Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8","volume":"10","author":"Corti","year":"1998","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib10","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0306-4522(01)00591-7","article-title":"Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS","volume":"110","author":"Corti","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib11","first-page":"8854","article-title":"Function of the thalamic reticular complex: the searchlight hypothesis. Proceedings of the National Academy of Science","volume":"94","author":"Crick","year":"1984","journal-title":"USA"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib12","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nrn811","article-title":"Childhood absence epilepsy: genes, channels, neurons and networks","volume":"3","author":"Crunelli","year":"2002","journal-title":"Nature Review Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib13","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/0006-8993(89)90399-5","article-title":"Suppressive effects of intranigral injection of muscimol in three models of generalized non-convulsive epilepsy induced by chemical agents","volume":"498","author":"Depaulis","year":"1989","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib14","doi-asserted-by":"crossref","first-page":"251","DOI":"10.2174\/1568007023339355","article-title":"The roles of metabotropic glutamate receptors in seizures and epilepsy. Current drug targets: CNS","volume":"1","author":"Doherty","year":"2002","journal-title":"Neurological Disorders"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib15","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0920-1211(91)90055-K","article-title":"Spike-wave discharges and sleep-wake states in rats with absence epilepsy","volume":"9","author":"Drinkenburg","year":"1991","journal-title":"Epilepsy Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-2999(95)00119-6","article-title":"Metabotropic glutamate receptor agonists inhibit endogenous glutamate release from rat striatal synaptosomes","volume":"277","author":"East","year":"1995","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib17","series-title":"The Mouse Brain in Stereotatic Coordinates","author":"Franklin","year":"1997"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib18","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.pneurobio.2005.01.002","article-title":"The reticular nucleus revisited: intrinsic and network properties of a thalamic pacemaker","volume":"75","author":"Fuentealba","year":"2005","journal-title":"Progress in Neurobiology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib19","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.1152\/jn.1994.71.6.2576","article-title":"Clonazepam suppresses GABAB-mediated inhibition in thalamic relay neurons through effects in nucleus reticularis","volume":"71","author":"Huguenard","year":"1994","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib20","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1126\/science.283.5401.541","article-title":"Reciprocal inhibitory connections and network synchrony in the mammalian thalamus","volume":"283","author":"Huntsman","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0006-8993(93)91641-5","article-title":"Thalamic multiple-unit activity underlying spike-wave discharges in anesthetized rats","volume":"612","author":"Inoue","year":"1993","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib22","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/1531-8249(200001)47:1<26::AID-ANA7>3.0.CO;2-P","article-title":"Up-regulation of the metabotropic glutamate vulnerability","volume":"47","author":"Lie","year":"2000","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/(SICI)1096-9861(19991108)414:1<67::AID-CNE6>3.0.CO;2-Z","article-title":"Predominance of corticothalamic synaptic inputs to thalamic reticular nucleus neurons in the rat","volume":"414","author":"Liu","year":"1999","journal-title":"The Journal of Comparative Neurology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib24","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0306-4522(92)90340-8","article-title":"Involvement of intrathalamic GABAB neurotransmission in the control of absence seizures in the rat","volume":"48","author":"Liu","year":"1992","journal-title":"Neuroscience"},{"issue":"Supplementum","key":"10.1016\/j.neuropharm.2007.10.004_bib25","first-page":"1","article-title":"Human absence epilepsies","volume":"35","author":"Loiseau","year":"1992","journal-title":"Journal of Neural Transmission"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0006-8993(99)02326-4","article-title":"Differential distribution of metabotropic glutamate receptor subtype mRNAs in the thalamus of the rat","volume":"854","author":"Lourenco Neto","year":"2000","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib27","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0028-3908(03)00271-5","article-title":"(\u2212)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection","volume":"45","author":"Maj","year":"2003","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib28","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0169-328X(95)00321-I","article-title":"Molecular characterization and localization of human metabotropic glutamate receptor type 4","volume":"37","author":"Makoff","year":"1996","journal-title":"Brain Research Molecular Brain Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib29","doi-asserted-by":"crossref","first-page":"13668","DOI":"10.1073\/pnas.1835724100","article-title":"Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment","volume":"11","author":"Marino","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib30","doi-asserted-by":"crossref","first-page":"885","DOI":"10.2174\/1568026054750263","article-title":"Targeting the metabotropic glutamate receptor mGluR4 for the treatment of diseases of the central nervous system","volume":"5","author":"Marino","year":"2005","journal-title":"Current Topics in Medicinal Chemistry"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib31","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev.neuro.20.1.185","article-title":"Sleep and arousal: thalamocortical mechanisms","volume":"20","author":"McCormick","year":"1997","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib32","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1523\/JNEUROSCI.22-04-01480.2002","article-title":"Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats","volume":"22","author":"Meeren","year":"2002","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib33","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1001\/archneur.62.3.371","article-title":"Evolving concepts on the pathophysiology of absence seizures: the cortical focus theory","volume":"62","author":"Meeren","year":"2005","journal-title":"Archives of Neurology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib34","doi-asserted-by":"crossref","first-page":"18712","DOI":"10.1073\/pnas.0508063102","article-title":"A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo. Proceedings of the National Academy of Science","volume":"102","author":"Mitsukawa","year":"2005","journal-title":"USA"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib35","doi-asserted-by":"crossref","first-page":"109","DOI":"10.2174\/1568007033482922","article-title":"Emerging signalling and protein interactions mediated via metabotropic glutamate receptors","volume":"2","author":"Moldrich","year":"2003","journal-title":"Current Drug Targets-CNS Neurological Disorders"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0014-2999(03)02149-6","article-title":"Glutamate metabotropic receptors as targets for drug therapy in epilepsy","volume":"476","author":"Moldrich","year":"2003","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib37","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/BF01217752","article-title":"The thalamic reticular nucleus of the adult rat: experimental anatomical studies","volume":"14","author":"Ohara","year":"1985","journal-title":"Journal of Neurocytology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib38","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/cne.903600402","article-title":"Distributions of the mRNAs for L-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain","volume":"360","author":"Ohishi","year":"1995","journal-title":"The Journal of Comparative Neurology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib39","series-title":"The Rat Brain in the Stereotaxic Coordinates","author":"Paxinos","year":"2005"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0028-3908(94)00129-G","article-title":"The metabotropic glutamate receptors: structure and functions","volume":"34","author":"Pin","year":"1995","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib41","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.nbd.2007.03.003","article-title":"Functional role of mGluR1 and mGluR4 in pilocarpine-induced temporal lobe epilepsy","volume":"26","author":"Pitsch","year":"2007","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib42","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0197-0186(95)00146-8","article-title":"Characterization of the metabotropic glutamate receptors (mGluRs) which modulate GABA-mediated inhibition in the ventrobasal thalamus","volume":"29","author":"Salt","year":"1996","journal-title":"Neurochemistry International"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib43","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1124\/mol.51.1.119","article-title":"Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile","volume":"51","author":"Saugstad","year":"1997","journal-title":"Molecular Pharmacology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib44","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/S0028-3908(99)00092-1","article-title":"Pharmacological agents acting at subtypes of metabotropic glutamate receptors","volume":"38","author":"Schoepp","year":"1999","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib45","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0924-8196(00)80044-5","article-title":"Metabotropic glutamate receptors immunocytochemical and in situ hybridization analyses","volume":"18","author":"Shigemoto","year":"2000","journal-title":"Handbook of Chemical Neuroanatomy"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib46","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0169-328X(00)00189-3","article-title":"Region-specific decline in the expression of metabotropic glutamate receptor 7 mRNA in rat brain during aging","volume":"82","author":"Simonyi","year":"2000","journal-title":"Brain Research Molecular Brain Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib47","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1097\/01.ALC.0000139825.35438.A4","article-title":"Chronic ethanol-induced subtype- and subregion-specific decrease in the mRNA expression of metabotropic glutamate receptors in rat hippocampus","volume":"28","author":"Simonyi","year":"2004","journal-title":"Alcoholism, Clinical and Experimental Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib48","first-page":"253","article-title":"Absence epilepsy: advances in experimental animal models","volume":"79","author":"Snead","year":"1999","journal-title":"Advances in Neurology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib49","doi-asserted-by":"crossref","first-page":"6218","DOI":"10.1523\/JNEUROSCI.20-16-06218.2000","article-title":"Modulation of absence seizures by the GABAA receptor: a critical role for metabotropic glutamate receptor 4 (mGluR4)","volume":"20","author":"Snead","year":"2000","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib50","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/hipo.10133","article-title":"Expression of plasma membrane GABA transporters but not of the vesicular GABA transporter in dentate granule cells after kainic acid seizures","volume":"13","author":"Sperk","year":"2003","journal-title":"Hippocampus"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0173(84)90017-1","article-title":"The thalamus as a neuronal oscillator","volume":"320","author":"Steriade","year":"1984","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib52","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1523\/JNEUROSCI.06-01-00068.1986","article-title":"Reticularis thalami neurons revisited: activity changes during shifts in states of vigilance","volume":"6","author":"Steriade","year":"1986","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib53","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1046\/j.1471-4159.1999.0720835.x","article-title":"Contribution of metabotropic glutamate receptor mGluR4 to L-2-[3H]amino-4-phosphonobutyrate binding in mouse brain","volume":"72","author":"Thomsen","year":"1999","journal-title":"Journal of Neurochemistry"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib54","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1152\/jn.1997.78.3.1748","article-title":"GABA(A)-receptor-mediated rebound burst firing and burst shunting in thalamus","volume":"78","author":"Ulrich","year":"1997","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib55","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0304-3940(86)90586-0","article-title":"Two types of electrocortical paroxysms in an inbred strain of rats","volume":"70","author":"van Luijtelaar","year":"1986","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib56","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0920-1211(88)90042-3","article-title":"Circadian rhythmicity in absence epilepsy in rats","volume":"2","author":"van Luijtelaar","year":"1988","journal-title":"Epilepsy Research"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib57","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.neubiorev.2006.03.002","article-title":"Global and focal aspects of absence epilepsy: the contribution of genetic models","volume":"30","author":"van Luijtelaar","year":"2006","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib58","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.neuroscience.2005.05.033","article-title":"Altered glutamate and GABA release within thalamocortical circuitry in metabotropic glutamate receptor 4 knockout mice","volume":"134","author":"Wang","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2007.10.004_bib59","first-page":"209","article-title":"Diagnosis and treatment of epilepsy","volume":"79","author":"Williams","year":"1953","journal-title":"Medical World"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390807003231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390807003231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,5]],"date-time":"2019-05-05T07:14:37Z","timestamp":1557040477000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390807003231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":59,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S0028390807003231"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2007.10.004","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2]]}}}