{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T08:14:50Z","timestamp":1793952890419,"version":"4.8.0"},"reference-count":80,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1016\/j.neuropharm.2008.01.012","type":"journal-article","created":{"date-parts":[[2008,2,14]],"date-time":"2008-02-14T09:20:02Z","timestamp":1202980802000},"page":"353-362","source":"Crossref","is-referenced-by-count":121,"title":["Plasticity and repair in the post-ischemic brain"],"prefix":"10.1016","volume":"55","author":[{"given":"Massimiliano","family":"Di Filippo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Tozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Belcastro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Tantucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Picconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Calabresi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2008.01.012_bib1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0006-8993(90)90184-D","article-title":"Anoxia reveals a vulnerable period in the development of long-term potentiation","volume":"511","author":"Arai","year":"1990","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib2","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.neuron.2007.07.035","article-title":"Rapid bidirectional switching of synaptic NMDA receptors","volume":"55","author":"Bellone","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib3","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1212\/01.wnl.0000242626.69666.e2","article-title":"A randomized, placebo-controlled study of donepezil in poststroke aphasia","volume":"67","author":"Berthier","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib4","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.expneurol.2006.11.008","article-title":"Transient ischemia increases neuronal nitric oxide synthase, argininosuccinate synthetase and argininosuccinate lyase co-expression in rat striatal neurons","volume":"204","author":"Bizzoco","year":"2007","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib5","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/361031a0","article-title":"A synaptic model of memory: long-term potentiation in the hippocampus","volume":"361","author":"Bliss","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib6","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1126\/science.7909958","article-title":"Postsynaptic induction and presynaptic expression of hippocampal long-term depression","volume":"264","author":"Bolshakov","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib7","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1161\/01.STR.0000189996.71237.f7","article-title":"The role of protein kinase C in cerebral ischemic and reperfusion injury","volume":"36","author":"Bright","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib8","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/nrn2214","article-title":"Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity","volume":"8","author":"Calabrese","year":"2007","journal-title":"Nature Reviews Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib9","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1111\/j.1460-9568.1992.tb00119.x","article-title":"Long-term potentiation in the striatum is unmasked by removing the voltage-dependent magnesium block of NMDA receptor channels","volume":"4","author":"Calabresi","year":"1992","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib10","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1093\/brain\/awf073","article-title":"Post-ischaemic long-term synaptic potentiation in the striatum: a putative mechanism for cell type-specific vulnerability","volume":"125","author":"Calabresi","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib11","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S1474-4422(03)00532-5","article-title":"Synaptic plasticity in the ischaemic brain","volume":"2","author":"Calabresi","year":"2003","journal-title":"Lancet Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib80","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/S1474-4422(06)70600-7","article-title":"A convergent model for cognitive dysfunctions in Parkinson's disease: the critical dopamine-acetylcholine synaptic balance","volume":"5","author":"Calabresi","year":"2006","journal-title":"Lancet Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib12","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.tins.2007.03.001","article-title":"Dopamine-mediated regulation of corticostriatal synaptic plasticity","volume":"30","author":"Calabresi","year":"2007","journal-title":"Trends in Neurosciences"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib13","doi-asserted-by":"crossref","first-page":"9278","DOI":"10.1523\/JNEUROSCI.2826-07.2007","article-title":"Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury","volume":"27","author":"Cao","year":"2007","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib14","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1093\/brain\/awf091","article-title":"Analysis of fMRI and finger tracking training in subjects with chronic stroke","volume":"125","author":"Carey","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib15","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.tins.2005.06.005","article-title":"The many faces of CREB","volume":"28","author":"Carlezon","year":"2005","journal-title":"Trends in Neurosciences"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib16","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.nbd.2007.03.012","article-title":"Synaptic plasticity during recovery from permanent occlusion of the middle cerebral artery","volume":"27","author":"Centonze","year":"2007","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib17","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1152\/jn.1996.75.2.770","article-title":"Intracellular injection of a Ca2+ chelator prevents generation of anoxic LTP","volume":"75","author":"Crepel","year":"1996","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib18","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1152\/jn.1993.70.5.2045","article-title":"A selective LTP of NMDA receptor-mediated currents induced by anoxia in CA1 hippocampal neurons","volume":"70","author":"Crepel","year":"1993","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib19","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1152\/jn.1993.69.5.1774","article-title":"Anoxia-induced LTP of isolated NMDA receptor-mediated synaptic responses","volume":"69","author":"Crepel","year":"1993","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib20","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0959-4388(00)00215-4","article-title":"NMDA receptor subunits: diversity, development and disease","volume":"11","author":"Cull-Candy","year":"2001","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib21","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0006-8993(90)90148-5","article-title":"Calpain inhibitors block long-term potentiation","volume":"534","author":"Denny","year":"1990","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib22","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.brainres.2004.07.059","article-title":"Ischemia-induced increase in long-term potentiation is warded off by specific calpain inhibitor PD150606","volume":"1024","author":"Farkas","year":"2004","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S1474-4422(03)00266-7","article-title":"Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century","volume":"2","author":"Feigin","year":"2003","journal-title":"Lancet Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib24","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1212\/01.wnl.0000172340.56307.5e","article-title":"Dopaminergic effects on encoding of a motor memory in chronic stroke","volume":"65","author":"Floel","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib25","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1212\/WNL.45.5.865","article-title":"Common drugs may influence motor recovery after stroke. The Sygen In Acute Stroke Study Investigators","volume":"45","author":"Goldstein","year":"1995","journal-title":"Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib26","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1152\/jn.1991.66.3.735","article-title":"Somatotopic mapping of the primary motor cortex in humans: activation studies with cerebral blood flow and positron emission tomography","volume":"66","author":"Grafton","year":"1991","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1097\/00004647-200102000-00001","article-title":"Programmed cell death in cerebral ischemia","volume":"21","author":"Graham","year":"2001","journal-title":"Journal of Cerebral Blood Flow and Metabolism"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib28","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/S0959-4388(99)00010-0","article-title":"Extracellular-signal-regulated kinase signalling in neurons","volume":"9","author":"Grewal","year":"1999","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib29","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.neuroscience.2006.11.039","article-title":"Different mechanisms account for extracellular-signal regulated kinase activation in distinct brain regions following global ischemia and reperfusion","volume":"145","author":"Ho","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib30","doi-asserted-by":"crossref","first-page":"11513","DOI":"10.1523\/JNEUROSCI.2259-06.2006","article-title":"Tonic and phasic nitric oxide signals in hippocampal long-term potentiation","volume":"26","author":"Hopper","year":"2006","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib31","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/ana.410360404","article-title":"Viability thresholds and the penumbra of focal ischemia","volume":"36","author":"Hossmann","year":"1994","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib32","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/sj.bjp.0701409","article-title":"Characterization of the anoxia-induced long-term synaptic potentiation in area CA1 of the rat hippocampus","volume":"122","author":"Hsu","year":"1997","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib33","doi-asserted-by":"crossref","first-page":"3525","DOI":"10.1097\/00001756-199810260-00035","article-title":"Protein kinase C inhibitors block generation of anoxia-induced long-term potentiation","volume":"9","author":"Hsu","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib34","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1111\/j.1460-9568.1997.tb01387.x","article-title":"Nitric oxide signalling is required for the generation of anoxia-induced long-term potentiation in the hippocampus","volume":"9","author":"Huang","year":"1997","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib35","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.neuron.2004.12.033","article-title":"Theta burst stimulation of the human motor cortex","volume":"45","author":"Huang","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib36","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1097\/01.wco.0000189876.37475.42","article-title":"Drivers of brain plasticity","volume":"18","author":"Hummel","year":"2005","journal-title":"Current Opinion in Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib37","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1161\/01.STR.22.5.648","article-title":"Amphetamine promotes recovery from sensory-motor integration deficit after thrombotic infarction of the primary somatosensory rat cortex","volume":"22","author":"Hurwitz","year":"1991","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib38","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1161\/01.STR.0000231875.96714.b1","article-title":"Temporal profiles of axon terminals, synapses and spines in the ischemic penumbra of the cerebral cortex: ultrastructure of neuronal remodeling","volume":"37","author":"Ito","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib39","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00004647-199801000-00010","article-title":"Oxygen deprivation produces delayed inhibition of long-term potentiation by activation of NMDA receptors and nitric oxide synthase","volume":"18","author":"Izumi","year":"1998","journal-title":"Journal of Cerebral Blood Flow and Metabolism"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib40","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1126\/science.286.5445.1745","article-title":"Building neural representations of habits","volume":"286","author":"Jog","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib41","doi-asserted-by":"crossref","first-page":"14518","DOI":"10.1073\/pnas.222536799","article-title":"The role of ipsilateral premotor cortex in hand movement after stroke","volume":"99","author":"Johansen-Berg","year":"2002","journal-title":"Proceedings of the National Academy of Science USA"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib42","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00004647-199803000-00007","article-title":"Preconditioning in vivo ischemia inhibits anoxic long-term potentiation and functionally protects CA1 neurons in the gerbil","volume":"18","author":"Kawai","year":"1998","journal-title":"Journal of Cerebral Blood Flow and Metabolism"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib43","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1038\/nn1747","article-title":"Spine growth precedes synapse formation in the adult neocortex in vivo","volume":"9","author":"Knott","year":"2006","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib44","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.1523\/JNEUROSCI.0116-07.2007","article-title":"NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo","volume":"27","author":"Liu","year":"2007","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib45","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nrn1867","article-title":"Adult neurogenesis and functional plasticity in neuronal circuits","volume":"7","author":"Lledo","year":"2006","journal-title":"Nature Reviews Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib46","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1161\/01.STR.0000153069.96296.fd","article-title":"Exciting, radical, suicidal: how brain cells die after stroke","volume":"36","author":"Lo","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib47","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/75714","article-title":"Synaptic plasticity and dynamic modulation of the postsynaptic membrane","volume":"3","author":"Luscher","year":"2000","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib48","doi-asserted-by":"crossref","first-page":"9204","DOI":"10.1523\/JNEUROSCI.21-23-09204.2001","article-title":"Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo","volume":"21","author":"Mabuchi","year":"2001","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib49","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.neuron.2004.09.012","article-title":"LTP and LTD: an embarrassment of riches","volume":"44","author":"Malenka","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib50","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1126\/science.285.5435.1870","article-title":"Long-term potentiation\u2014a decade of progress?","volume":"285","author":"Malenka","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib51","first-page":"CD002090","article-title":"Amphetamines for improving recovery after stroke","volume":"1","author":"Martinsson","year":"2007","journal-title":"Cochrane database of systematic reviews"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib52","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0304-3940(02)00961-8","article-title":"Autophosphorylated calcium\/calmodulin-dependent protein kinase II alpha induced by cerebral ischemia immediately targets and phosphorylates N-methyl-d-aspartate receptor subunit 2B (NR2B) in hippocampus of rats","volume":"333","author":"Meng","year":"2002","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib53","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/S0165-6147(00)89070-7","article-title":"NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release","volume":"16","author":"Mody","year":"1995","journal-title":"Trends in Pharmacological Sciences"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib54","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1682\/JRRD.2003.07.0108","article-title":"Donepezil as an adjuvant to constraint-induced therapy for upper-limb dysfunction after stroke: an exploratory randomized clinical trial","volume":"41","author":"Nadeau","year":"2004","journal-title":"Journal of rehabilitation research and development"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib55","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1161\/01.STR.0000247943.12887.d2","article-title":"Postinfarct cortical plasticity and behavioral recovery","volume":"38","author":"Nudo","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib56","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1126\/science.272.5269.1791","article-title":"Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct","volume":"272","author":"Nudo","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib57","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.brainres.2004.10.063","article-title":"Acquisition of ischemic tolerance by repetitive transcranial magnetic stimulation in the rat hippocampus","volume":"1037","author":"Ogiue-Ikeda","year":"2005","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib58","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.neuron.2005.01.008","article-title":"Toward establishing a therapeutic window for rTMS by theta burst stimulation","volume":"45","author":"Paulus","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib59","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1161\/01.STR.0000226981.57777.b0","article-title":"NR2B subunit exerts a critical role in postischemic synaptic plasticity","volume":"37","author":"Picconi","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib60","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.brainres.2007.02.065","article-title":"Exercise intensity influences the temporal profile of growth factors involved in neuronal plasticity following focal ischemia","volume":"1150","author":"Ploughman","year":"2007","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib61","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.brainres.2006.06.063","article-title":"Axonal plasticity is associated with motor recovery following amphetamine treatment combined with rehabilitation after brain injury in the adult rat","volume":"1111","author":"Ramic","year":"2006","journal-title":"Brain Research"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib62","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S1474-4422(03)00485-X","article-title":"Post-stroke plastic reorganisation in the adult brain","volume":"2","author":"Rossini","year":"2003","journal-title":"Lancet Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib63","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1161\/01.STR.28.6.1283","article-title":"Nitric oxide synthase in models of focal ischemia","volume":"6","author":"Samdani","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib64","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nrn1588","article-title":"Choline transporters, cholinergic transmission and cognition","volume":"6","author":"Sarter","year":"2005","journal-title":"Nature Reviews Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib65","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.1161\/01.STR.0000038093.42512.0F","article-title":"Endogenous dopamine amplifies ischemic long-term potentiation via D1 receptors","volume":"33","author":"Saulle","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib66","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1038\/jcbfm.1995.56","article-title":"Effect of cerebral ischemia on calcium\/calmodulin-dependent protein kinase II activity and phosphorylation","volume":"15","author":"Shackelford","year":"1995","journal-title":"Journal of cerebral blood flow and metabolism"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib67","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/WCO.0b013e32801080d1","article-title":"Does brain stimulation after stroke have a future?","volume":"19","author":"Talelli","year":"2006","journal-title":"Current Opinion in Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib68","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0306-4522(00)00289-X","article-title":"Activated phosphorylation of cyclic AMP response element binding protein is associated with preservation of striatal neurons after focal cerebral ischemia in the rat","volume":"100","author":"Tanaka","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib69","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.expneurol.2007.06.008","article-title":"Memantine reduces neuronal dysfunctions triggered by in vitro ischemia and 3-nitropropionic acid","volume":"207","author":"Tozzi","year":"2007","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib70","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/6368","article-title":"Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus","volume":"2","author":"van Praag","year":"1999","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib71","doi-asserted-by":"crossref","first-page":"13427","DOI":"10.1073\/pnas.96.23.13427","article-title":"Running enhances neurogenesis, learning, and long-term potentiation in mice","volume":"96","author":"van Praag","year":"1999","journal-title":"Proceedings of the National Academy of Science USA"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib72","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1007\/s00415-004-0583-0","article-title":"Long-term prognosis of ischemic stroke in young adults. Study of 272 cases","volume":"251","author":"Varona","year":"2004","journal-title":"Journal of Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib73","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/ana.410310502","article-title":"Functional reorganization of the brain in recovery from striatocapsular infarction in man","volume":"31","author":"Weiller","year":"1992","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib74","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/ana.410330208","article-title":"Individual patterns of functional reorganization in the human cerebral cortex after capsular infarction","volume":"33","author":"Weiller","year":"1993","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib75","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1126\/science.1128134","article-title":"Learning induces long-term potentiation in the hippocampus","volume":"313","author":"Whitlock","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib76","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/nrn1406","article-title":"Dopamine, learning and motivation","volume":"5","author":"Wise","year":"2004","journal-title":"Nature Reviews Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib77","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1385\/MN:33:3:215","article-title":"Calpain and synaptic function","volume":"33","author":"Wu","year":"2006","journal-title":"Molecular Neurobiology"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib78","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.cell.2004.08.026","article-title":"Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels","volume":"118","author":"Xiong","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.neuropharm.2008.01.012_bib79","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0006-8993(01)02594-X","article-title":"Long-term potentiation protects rat hippocampal slices from the effects of acute hypoxia","volume":"907","author":"Youssef","year":"2001","journal-title":"Brain Research"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390808000373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390808000373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T22:19:13Z","timestamp":1557267553000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390808000373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":80,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S0028390808000373"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2008.01.012","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}