{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T07:34:49Z","timestamp":1762673689281,"version":"3.35.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.neuropharm.2008.08.010","type":"journal-article","created":{"date-parts":[[2008,8,20]],"date-time":"2008-08-20T12:29:09Z","timestamp":1219235349000},"page":"161-173","source":"Crossref","is-referenced-by-count":16,"title":["Context-dependent modulation of \u03b1\u03b2\u03b3 and \u03b1\u03b2\u03b4 GABAA receptors by penicillin: Implications for phasic and tonic inhibition"],"prefix":"10.1016","volume":"56","author":[{"given":"Hua-Jun","family":"Feng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel J.","family":"Botzolakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Macdonald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2008.08.010_bib1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1113\/jphysiol.1977.sp011858","article-title":"Voltage jump analysis of procaine action at frog end-plate","volume":"268","author":"Adams","year":"1977","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib2","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1113\/jphysiol.1978.sp012299","article-title":"The mode of action of antagonists of the excitatory response to acetylcholine in Aplysia neurons","volume":"278","author":"Ascher","year":"1978","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1113\/jphysiol.1979.sp012958","article-title":"Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells","volume":"295","author":"Ascher","year":"1979","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib4","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/sj.bjp.0703063","article-title":"Modulation by bicuculline and penicillin of the block by t-butyl-bicyclo-phosphorothionate (TBPS) of GABAA-receptor mediated Cl\u2212-current responses in rat striatal neurones","volume":"129","author":"Behrends","year":"2000","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1113\/jphysiol.2002.020255","article-title":"Slow phases of GABAA receptor desensitization: structural determinants and possible relevance for synaptic function","volume":"544","author":"Bianchi","year":"2002","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib6","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1113\/jphysiol.2007.142364","article-title":"Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation","volume":"584","author":"Bianchi","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib7","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/cne.10102","article-title":"Intact sorting, targeting, and clustering of \u03b3-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro","volume":"443","author":"Brunig","year":"2002","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib8","doi-asserted-by":"crossref","first-page":"8454","DOI":"10.1523\/JNEUROSCI.2063-04.2004","article-title":"Selective enhancement of tonic GABAergic inhibition in murine hippocampal neurons by low concentrations of the volatile anesthetic isoflurane","volume":"24","author":"Caraiscos","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib9","doi-asserted-by":"crossref","first-page":"15230","DOI":"10.1073\/pnas.0604304103","article-title":"GABAA receptor \u03b14 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol","volume":"103","author":"Chandra","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib10","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1476-5381.1986.tb10234.x","article-title":"Convulsant doses of penicillin shorten the lifetime of GABA-induced channels in cultured central neurones","volume":"88","author":"Chow","year":"1986","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib11","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/2798","article-title":"Postsynaptic clustering of major GABAA receptor subtypes requires the \u03b32 subunit and gephyrin","volume":"1","author":"Essrich","year":"1998","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib12","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/nrn1625","article-title":"Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors","volume":"6","author":"Farrant","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib13","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1124\/mol.104.003426","article-title":"Multiple actions of propofol on \u03b1\u03b2\u03b3 and \u03b1\u03b2\u03b4 GABAA receptors","volume":"66","author":"Feng","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib14","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1124\/mol.104.002543","article-title":"Pentobarbital differentially modulates \u03b11\u03b23\u03b4 and \u03b11\u03b23\u03b32L GABAA receptor currents","volume":"66","author":"Feng","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib15","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1113\/jphysiol.2007.134460","article-title":"The main source of ambient GABA responsible for tonic inhibition in the mouse hippocampus","volume":"582","author":"Glykys","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib16","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/nn1813","article-title":"A new naturally occurring GABAA receptor subunit partnership with high sensitivity to ethanol","volume":"10","author":"Glykys","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib17","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0028-3908(96)00150-5","article-title":"Expression of functional GABAA receptors in transfected L929 cells isolated by immunomagnetic bead separation","volume":"36","author":"Greenfield","year":"1997","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2008.08.010_bib18","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1469-7793.1999.027af.x","article-title":"GABAA receptor subunit \u03b32 and \u03b4 subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts","volume":"514","author":"Haas","year":"1999","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib19","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/j.1476-5381.1992.tb14515.x","article-title":"The pharmacology of recombinant GABAA receptors containing bovine \u03b11, \u03b21, \u03b32L subunits stably transfected into mouse fibroblast L-cells","volume":"107","author":"Horne","year":"1992","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib20","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1152\/jn.00780.2002","article-title":"Neurosteroid effects of GABAergic synaptic plasticity in hippocampus","volume":"89","author":"Hsu","year":"2003","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0920-1211(99)00078-9","article-title":"Seizures induced by penicillin microinjections in the mesencephalic tegmentum","volume":"38","author":"Jimenez","year":"2000","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib22","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0896-6273(95)90075-6","article-title":"Desensitized states prolong GABAA channel responses to brief agonist pulses","volume":"15","author":"Jones","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2008.08.010_bib23","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0166-2236(96)80037-3","article-title":"The impact of receptor desensitization on fast synaptic transmission","volume":"19","author":"Jones","year":"1996","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib24","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0006-8993(92)91057-L","article-title":"Penicillin-induced triphasic modulation of GABAA receptor-operated chloride current in frog sensory neuron","volume":"595","author":"Katayama","year":"1992","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib25","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1113\/jphysiol.1957.sp005838","article-title":"A study of the desensitization produced by acetylcholine at the motor end-plate","volume":"138","author":"Katz","year":"1957","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib26","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/S0026-895X(25)08736-X","article-title":"Homomeric \u03b21 \u03b3-aminobutyric acid A receptor-ion channels: evaluation of pharmacological and physiological properties","volume":"49","author":"Krishek","year":"1996","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib27","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1113\/jphysiol.2006.122135","article-title":"Enhanced macroscopic desensitization shapes the response of \u03b14 subunit-containing GABAA receptors to synaptic and extrasynaptic GABA","volume":"578","author":"Lagrange","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib28","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1113\/jphysiol.2005.099093","article-title":"Modes and models of GABAA receptor gating","volume":"572","author":"Lema","year":"2006","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib29","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1523\/JNEUROSCI.4702-05.2006","article-title":"Chronic intermittent ethanol-induced switch of ethanol actions from extrasynaptic to synaptic hippocampal GABAA receptors","volume":"26","author":"Liang","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib30","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ejphar.2004.06.004","article-title":"Penicillin blocks human \u03b11\u03b21 and \u03b11\u03b21\u03b32S GABAA channels that open spontaneously","volume":"496","author":"Lindquist","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib31","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/nrd1958","article-title":"Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond","volume":"5","author":"Lipton","year":"2006","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib32","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.pharmthera.2004.04.003","article-title":"Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses","volume":"102","author":"Luscher","year":"2004","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib33","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/267720a0","article-title":"Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurons","volume":"267","author":"Macdonald","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2008.08.010_bib34","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S1054-3589(06)54007-4","article-title":"GABAA receptor mutations associated with generalized epilepsies","volume":"54","author":"Macdonald","year":"2006","journal-title":"Adv. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib35","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1113\/jphysiol.1978.sp012301","article-title":"Nose and relaxation studies of acetylcholine induced currents in the presence of procaine","volume":"278","author":"Marty","year":"1978","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib36","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0166-2236(96)80023-3","article-title":"Which GABAA-receptor subtypes really occur in the brain?","volume":"19","author":"McKernan","year":"1996","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib37","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.tins.2004.07.002","article-title":"Diversity of inhibitory neurotransmission through GABAA receptors","volume":"27","author":"Mody","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib38","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1152\/jn.00951.2002","article-title":"Binding sites, singly bound states, and conformation coupling shape GABA-evoked currents","volume":"89","author":"Mozrzymas","year":"2003","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib39","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.neuropharm.2004.07.003","article-title":"Dynamism of GABAA receptor activation shapes the \u201cpersonality\u201d of inhibitory synapses","volume":"47","author":"Mozrzymas","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2008.08.010_bib40","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1124\/mol.105.016683","article-title":"High-affinity, slowly desensitizing GABAA receptors mediate tonic inhibition in hippocampal dentate granule cells","volume":"69","author":"Mtchedlishvili","year":"2005","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib41","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1113\/jphysiol.1978.sp012267","article-title":"Local anesthetics transiently block currents through single acetylcholine-receptor channels","volume":"277","author":"Neher","year":"1978","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib42","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1523\/JNEUROSCI.18-05-01693.1998","article-title":"Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells","volume":"18","author":"Nusser","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib43","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1152\/jn.2002.87.5.2624","article-title":"Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells","volume":"87","author":"Nusser","year":"2002","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib44","series-title":"Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology","first-page":"202","article-title":"GABAA receptor complex: structure and function","author":"Olsen","year":"2002"},{"key":"10.1016\/j.neuropharm.2008.08.010_bib45","doi-asserted-by":"crossref","first-page":"8629","DOI":"10.1523\/JNEUROSCI.2877-04.2004","article-title":"Altered expression of the \u03b4 subunit of the GABAA receptor in a mouse model of temporal lobe epilepsy","volume":"24","author":"Peng","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib46","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1046\/j.1471-4159.2003.02135.x","article-title":"Subunit composition and quantitative importance of GABAA receptor subtypes in the cerebellum of mouse and rat","volume":"87","author":"Poltl","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib47","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1529\/biophysj.104.055814","article-title":"GABAA receptor kinetics in the cerebellar nuclei: evidence for detection of transmitter from distant release sites","volume":"88","author":"Pugh","year":"2005","journal-title":"Biophys. J."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib48","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1113\/jphysiol.1977.sp011659","article-title":"A quantitative analysis of local anesthetic alteration of miniature end-plate currents and end-plate current fluctuations","volume":"264","author":"Ruff","year":"1977","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib49","doi-asserted-by":"crossref","first-page":"7077","DOI":"10.1523\/JNEUROSCI.14-11-07077.1994","article-title":"Assembly of GABAA receptor subunits: role of the \u03b4 subunit","volume":"14","author":"Saxena","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib50","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0306-4522(94)90594-0","article-title":"Hippocampal plasticity following epileptiform bursting produced by GABAA antagonists","volume":"59","author":"Schneiderman","year":"1994","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.08.010_bib51","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/S0306-4522(97)00209-1","article-title":"The role of long-term potentiation in persistent epileptiform burst-induced hyperexcitability following GABAA receptor blockade","volume":"81","author":"Schneiderman","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2008.08.010_bib52","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.tins.2004.03.005","article-title":"Tonically active GABAA receptors: modulating gain and maintaining the tone","volume":"27","author":"Semyanov","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib53","first-page":"313","article-title":"In vivo microdialysis study of excitatory and inhibitory amino acid levels in the hippocampus following penicillin-induced seizures in mature rats","volume":"43","author":"Shen","year":"2002","journal-title":"Acta Paediatr. Taiwan."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1523\/JNEUROSCI.22-10-j0003.2002","article-title":"Receptors with different affinities mediate phasic and tonic GABAA conductances in hippocampal neurons","volume":"22","author":"Stell","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib55","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/sj.bjp.0704496","article-title":"The \u03b2-lactam antibiotics, penicillin-G and cefoselis have different mechanisms and sites of action at GABAA receptors","volume":"135","author":"Sugimoto","year":"2002","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib56","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.brainres.2004.09.056","article-title":"Distribution of \u03b11, \u03b14, \u03b32, and \u03b4 subunits of GABAA receptors in hippocampal granule cells","volume":"1029","author":"Sun","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib57","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1124\/mol.56.1.110","article-title":"Preferential coassembly of \u03b14 and \u03b4 subunits of the \u03b3-aminobutyric acidA receptor in rat thalamus","volume":"56","author":"Sur","year":"1999","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib58","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s002329900128","article-title":"Effects of mutating leucine to threonine in the M2 segment of \u03b11 and \u03b21 subunits of GABAA \u03b11\u03b21 receptors","volume":"154","author":"Tierney","year":"1996","journal-title":"J. Membr. Biol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00966719","article-title":"Effect of penicillin on GABA-gated chloride ion influx","volume":"19","author":"Tsuda","year":"1994","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib60","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1113\/jphysiol.1992.sp018914","article-title":"Kinetics of open channel block by penicillin of single GABAA receptor channels from mouse spinal cord neurones in culture","volume":"445","author":"Twyman","year":"1992","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib61","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0920-1211(96)00078-2","article-title":"Antiseizure activity of insulin: insulin inhibits pentylenetetrazole, penicillin and kainic acid-induced seizures in rats","volume":"25","author":"Uysal","year":"1996","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib62","doi-asserted-by":"crossref","first-page":"10650","DOI":"10.1523\/JNEUROSCI.23-33-10650.2003","article-title":"Perisynaptic localization of \u03b4 subunit-containing GABAA receptors and their activation by GABA spillover in the mouse dentate gyrus","volume":"23","author":"Wei","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib63","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1523\/JNEUROSCI.12-03-01040.1992","article-title":"The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon","volume":"12","author":"Wisden","year":"1992","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib64","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1523\/JNEUROSCI.22-05-01541.2002","article-title":"Enhanced neurosteroid potentiation of ternary GABAA receptors containing the \u03b4 subunit","volume":"22","author":"Wohlfarth","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib65","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1124\/mol.63.1.2","article-title":"Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA","volume":"63","author":"Yeung","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2008.08.010_bib66","doi-asserted-by":"crossref","first-page":"7520","DOI":"10.1523\/JNEUROSCI.1555-07.2007","article-title":"Altered localization of GABAA receptor subunits on dentate granule cell dendrites influences tonic and phasic inhibition in a mouse model of epilepsy","volume":"27","author":"Zhang","year":"2007","journal-title":"J. Neurosci."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390808003742?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390808003742?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T15:58:28Z","timestamp":1738339108000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390808003742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":66,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0028390808003742"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2008.08.010","relation":{},"ISSN":["0028-3908"],"issn-type":[{"type":"print","value":"0028-3908"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}