{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:47:02Z","timestamp":1759682822178,"version":"3.37.0"},"reference-count":46,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.neuropharm.2009.01.003","type":"journal-article","created":{"date-parts":[[2009,1,19]],"date-time":"2009-01-19T09:20:55Z","timestamp":1232356855000},"page":"798-807","source":"Crossref","is-referenced-by-count":7,"title":["Induction of Fos proteins in regions of the nucleus accumbens and ventrolateral striatum correlates with catalepsy and stereotypic behaviours induced by morphine"],"prefix":"10.1016","volume":"56","author":[{"given":"Adam S.","family":"Hamlin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavan P.","family":"McNally","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Fred Westbrook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peregrine B.","family":"Osborne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2009.01.003_bib1","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.1523\/JNEUROSCI.15-05-03328.1995","article-title":"Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord","volume":"15","author":"Arvidsson","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib2","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1046\/j.1460-9568.1999.00525.x","article-title":"Functional heterogeneity in dopamine release and in the expression of fos-like proteins within the rat striatal complex","volume":"11","author":"Barrot","year":"1999","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0091-3057(92)90438-L","article-title":"Lesions of the tegmental pedunculopontine nucleus: effects on the locomotor activity induced by morphine and amphetamine","volume":"42","author":"Bechara","year":"1992","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib4","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1523\/JNEUROSCI.12-06-02079.1992","article-title":"Compartmental distribution of ventral striatal neurons projecting to the mesencephalon in the rat","volume":"12","author":"Berendse","year":"1992","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib5","doi-asserted-by":"crossref","first-page":"8596","DOI":"10.1523\/JNEUROSCI.17-21-08596.1997","article-title":"Systemic morphine-induced fos protein in the rat striatum and nucleus accumbens is regulated by \u03bc opioid receptors in the substantia nigra and ventral tegmental area","volume":"17","author":"Bontempi","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib6","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0028-3908(83)90246-0","article-title":"Reversal of morphine-induced catalepsy in the rat by narcotic antagonists and their quaternary derivatives","volume":"22","author":"Brown","year":"1983","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib7","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0306-4522(98)00466-7","article-title":"Reciprocal changes in dopamine responsiveness in the nucleus accumbens shell and core and in the dorsal caudate-putamen in rats sensitized to morphine","volume":"90","author":"Cadoni","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib8","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/73949","article-title":"A measure of striatal function predicts motor stereotypy","volume":"3","author":"Canales","year":"2000","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib10","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1007\/BF02532384","article-title":"Psychomotor stimulant- and opiate-induced c-fos mRNA expression patterns in the rat forebrain: comparisons between acute drug treatment and a drug challenge in sensitized animals","volume":"21","author":"Curran","year":"1996","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib11","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0006-8993(02)02312-0","article-title":"Heroin sensitization as mapped by c-Fos immunoreactivity in the rat striatum","volume":"933","author":"D'Este","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib12","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0006-8993(80)90781-7","article-title":"Morphine versus haloperidol catalepsy in the rat: a behavioral analysis of postural support mechanisms","volume":"201","author":"De Ryck","year":"1980","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0169-328X(99)00184-9","article-title":"Long-lasting sensitization towards morphine in motoric and limbic areas as determined by c-fos expression in rat brain","volume":"72","author":"Erdtmann-Vourliotis","year":"1999","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib14","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/S0006-8993(99)01579-6","article-title":"Chronic administration of morphine alters immediate-early gene expression in the forebrain of post-dependent rats","volume":"835","author":"Frankel","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib15","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0306-4522(02)00312-3","article-title":"Preprodynorphin-, preproenkephalin-, preprotachykinin a- and preprotachykinin B-immunoreactive neurons in the accumbens nucleus and olfactory tubercle: double-immunofluorescence analysis","volume":"114","author":"Furuta","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib16","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0006-8993(95)00625-Z","article-title":"Alterations in immediate-early gene proteins in the rat forebrain induced by acute morphine injection","volume":"692","author":"Garcia","year":"1995","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib17","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1146\/annurev.ne.15.030192.001441","article-title":"The neostriatal mosaic: multiple levels of compartmental organization in the basal ganglia","volume":"15","author":"Gerfen","year":"1992","journal-title":"Ann. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib18","series-title":"Handbook of Chemical Neuroanatomy: Integrated Systems of the CNS. Part III","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0924-8196(96)80004-2","article-title":"The basal ganglia","author":"Gerfen","year":"1996"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib19","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/0304-3940(85)90463-X","article-title":"Lesions of ventral tegmental dopamine neurons delay the development of tolerance to morphine catalepsy","volume":"55","author":"Hand","year":"1985","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib20","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1046\/j.0953-816x.2001.01877.x","article-title":"The anabolic androgenic steroid, nandrolone decanoate, increases the density of fos-like immunoreactive neurons in limbic regions of guinea-pig brain","volume":"15","author":"Johansson-Steensland","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib21","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1007\/BF00172976","article-title":"Induction of oral stereotypy following amphetamine microinjection into a discrete subregion of the striatum","volume":"95","author":"Kelley","year":"1988","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib22","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0304-3940(01)02457-0","article-title":"Opiate-induced motor stimulation is regulated by gamma-aminobutyric acid type B receptors found in the ventral tegmental area in mice","volume":"317","author":"Leite-Morris","year":"2002","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib23","doi-asserted-by":"crossref","first-page":"8537","DOI":"10.1073\/pnas.91.18.8537","article-title":"Morphine induces c-fos and junB in striatum and nucleus accumbens via D1 and N-methyl-d-aspartate receptors","volume":"91","author":"Liu","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib24","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0891-0618(95)00055-C","article-title":"Immunohistochemical localization of the cloned mu opioid receptor in the rat CNS","volume":"8","author":"Mansour","year":"1995","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0896-6273(00)80288-3","article-title":"Network-level changes in expression of inducible Fos\u2013Jun proteins in the striatum during chronic cocaine treatment and withdrawal","volume":"17","author":"Moratalla","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0006-8993(98)01191-3","article-title":"DeltaFosB: a molecular mediator of long-term neural and behavioral plasticity","volume":"835","author":"Nestler","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib26","doi-asserted-by":"crossref","first-page":"11042","DOI":"10.1073\/pnas.191352698","article-title":"DeltaFosB: a sustained molecular switch for addiction","volume":"98","author":"Nestler","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib29","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1177\/002215540004801108","article-title":"Localization of transcription factor AP-1 family proteins in ameloblast nuclei of the rat incisor","volume":"48","author":"Nishikawa","year":"2000","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib28","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/S0026-895X(25)08777-2","article-title":"Induction of chronic Fos-related antigens in rat brain by chronic morphine administration","volume":"49","author":"Nye","year":"1996","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib30","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0006-8993(94)90805-2","article-title":"Lesions of the pedunculopontine tegmental nucleus abolish catalepsy and locomotor depression induced by morphine","volume":"662","author":"Olmstead","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib31","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.neuroscience.2004.11.043","article-title":"Localization of immunoreactivity for DCC, the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents","volume":"131","author":"Osborne","year":"2005","journal-title":"Neuroscience"},{"year":"1997","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","key":"10.1016\/j.neuropharm.2009.01.003_bib32"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib33","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0278-5846(88)90038-3","article-title":"Regional specialization of motor functions in the rat striatum: implications for the treatment of parkinsonism","volume":"12","author":"Pisa","year":"1988","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatr."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib34","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0376-8716(00)00167-8","article-title":"Parametric evaluation of the development of sensitization to the effects of morphine on locomotor activity","volume":"62","author":"Powell","year":"2001","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib35","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/s002130000480","article-title":"Morphine and amphetamine sensitization in rats demonstrated under moderate- and high-dose NMDA receptor blockade with MK-801 (dizocilpine)","volume":"151","author":"Ranaldi","year":"2000","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib36","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/1098-2396(200102)39:2<122::AID-SYN3>3.0.CO;2-R","article-title":"FosB in rat striatum: normal regional distribution and enhanced expression after 6-month haloperidol administration","volume":"39","author":"Rodriguez","year":"2001","journal-title":"Synapse"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib37","doi-asserted-by":"crossref","first-page":"4049","DOI":"10.1038\/sj.onc.1210193","article-title":"Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo","volume":"26","author":"Schwartz","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib38","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0166-4328(94)00146-7","article-title":"NMDA and D1 receptors mediate induction of c-fos and junB genes in striatum following morphine administration: implications for studies of memory","volume":"66","author":"Sharp","year":"1995","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib39","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0014-2999(98)00298-2","article-title":"Metamizol potentiates morphine effects on visceral pain and evoked c-Fos immunoreactivity in spinal cord","volume":"351","author":"Taylor","year":"1998","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib42","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s002130050273","article-title":"Morphine-induced long-term sensitization to the locomotor effects of morphine and amphetamine depends on the temporal pattern of the pretreatment regimen","volume":"131","author":"Vanderschuren","year":"1997","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib40","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1046\/j.0953-816x.2001.01775.x","article-title":"A single exposure to morphine induces long-lasting behavioural and neurochemical sensitization in rats","volume":"14","author":"Vanderschuren","year":"2001","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib41","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1046\/j.1460-9568.2002.02308.x","article-title":"Compartment-specific changes in striatal neuronal activity during expression of amphetamine sensitization are the result of drug hypersensitivity","volume":"16","author":"Vanderschuren","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib43","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S0022-3565(25)31487-4","article-title":"Tolerance development to the biphasic effects of morphine on locomotor activity and brain acetylcholine in the rat","volume":"207","author":"Vasko","year":"1978","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib44","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/0006-8993(89)91140-2","article-title":"The effect of dopamine receptor blockade on the development of sensitization to the locomotor activating effects of amphetamine and morphine","volume":"499","author":"Vezina","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib45","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0306-4522(02)00153-7","article-title":"Endomorphin-2 immunoreactivity in the cervical dorsal horn of the rat spinal cord at the electron microscopic level","volume":"113","author":"Wang","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2009.01.003_bib46","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0091-3057(83)90250-2","article-title":"Reversal of morphine-induced catalepsy by naloxone microinjections into brain regions with high opiate receptor binding: a preliminary report","volume":"18","author":"Wilcox","year":"1983","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2009.01.003_bib47","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1615\/CritRevNeurobiol.v11.i4.10","article-title":"On the relationships between the striatum and the pedunculopontine tegmental nucleus","volume":"11","author":"Winn","year":"1997","journal-title":"Crit. Rev. Neurobiol."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390809000045?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390809000045?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T01:35:29Z","timestamp":1738892129000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390809000045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0028390809000045"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2009.01.003","relation":{},"ISSN":["0028-3908"],"issn-type":[{"type":"print","value":"0028-3908"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}